Background Doxorubicin (Dox) is one of the most potent anticancer drugs, but its successful
use is hampered by high toxicity caused mainly by generation of reactive oxygen species. …

The main aim of this work was to evaluate the effect of doxorubicin in complex with C 60
fullerene (C 60 + Dox) on the growth and metastasis of Lewis lung carcinoma in mice and to …

Toxicity of the C 60 fullerene aqueous colloid solution in vitro and in vivo experiments was
studied. C 60 fullerene in the concentration range of 3.6–144 µg/mL demonstrated low toxicity …

The self-organization of C 60 fullerene and cisplatin in aqueous solution was investigated
using the computer simulation, dynamic light scattering and atomic force microscopy …

Cisplatin (Cis-Pt) is the cytotoxic agent widely used against tumors of various origin, but its
therapeutic efficiency is substantially limited by a non-selective effect and high toxicity. …

We formulated and analyzed a novel nanoformulation of the anticancer drug cisplatin (Cis)
with C 60 fullerene (C 60 +Cis complex) and showed its higher toxicity toward tumor cell lines …

Recent progress in nanobiotechnology has attracted interest to a biomedical application of
the carbon nanostructure C 60 fullerene since it possesses a unique structure and versatile …

A nanosized drug complex was explored to improve the efficiency of cancer chemotherapy,
complementing it with nanodelivery and photodynamic therapy. For this, nanomolar amounts …

Influence of C 60 fullerenes and C 60 containing composites on the basis of aminopropylaerosil
on erythrocytes resistance to the acid haemolysis and viability of thymocytes, Erlich …

Conventional anticancer chemotherapy is limited because of severe side effects as well as
a quickly evolving multidrug resistance of the tumor cells. To address this problem, we have …