rMATS: robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
Ultra-deep RNA sequencing (RNA-Seq) has become a powerful approach for genome-wide
analysis of pre-mRNA alternative splicing. We previously developed multivariate analysis of …
analysis of pre-mRNA alternative splicing. We previously developed multivariate analysis of …
MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data
Ultra-deep RNA sequencing has become a powerful approach for genome-wide analysis of
pre-mRNA alternative splicing. We develop MATS (multivariate analysis of transcript splicing…
pre-mRNA alternative splicing. We develop MATS (multivariate analysis of transcript splicing…
Dytanvo: Joint refinement of visual odometry and motion segmentation in dynamic environments
Learning-based visual odometry (VO) algorithms achieve remarkable performance on
common static scenes, benefiting from high-capacity models and massive annotated data, but …
common static scenes, benefiting from high-capacity models and massive annotated data, but …
An ESRP‐regulated splicing programme is abrogated during the epithelial–mesenchymal transition
…, P Jiang, K Amirikian, KA Dittmar, H Lu, S Shen… - The EMBO …, 2010 - embopress.org
Alternative splicing achieves coordinated changes in post‐transcriptional gene expression
programmes through the activities of diverse RNA‐binding proteins. Epithelial splicing …
programmes through the activities of diverse RNA‐binding proteins. Epithelial splicing …
Computation offloading with multiple agents in edge-computing–supported IoT
With the development of the Internet of Things (IoT) and the birth of various new IoT devices,
the capacity of massive IoT devices is facing challenges. Fortunately, edge computing can …
the capacity of massive IoT devices is facing challenges. Fortunately, edge computing can …
Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice
Huntington's disease (HD) is a fatal neurodegenerative disease caused by mutant huntingtin
(htt) protein, and there are currently no effective treatments. Recently, we and others …
(htt) protein, and there are currently no effective treatments. Recently, we and others …
The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events
CC Warzecha, S Shen, Y Xing, RP Carstens - RNA biology, 2009 - Taylor & Francis
Cell-type and tissue-specific alternative splicing events are regulated by combinatorial
control involving both abundant RNA binding proteins as well as those with more discrete …
control involving both abundant RNA binding proteins as well as those with more discrete …
Widespread establishment and regulatory impact of Alu exons in human genes
The Alu element has been a major source of new exons during primate evolution. Thousands
of human genes contain spliced exons derived from Alu elements. However, identifying …
of human genes contain spliced exons derived from Alu elements. However, identifying …
SURVIV for survival analysis of mRNA isoform variation
The rapid accumulation of clinical RNA-seq data sets has provided the opportunity to
associate mRNA isoform variations to clinical outcomes. Here we report a statistical method …
associate mRNA isoform variations to clinical outcomes. Here we report a statistical method …
Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing
…, JW Park, K Amirikian, J Wan, S Shen… - … and cellular biology, 2012 - Taylor & Francis
Tissue-specific alternative splicing is achieved through the coordinated assembly of RNA
binding proteins at specific sites to enhance or silence splicing at nearby splice sites. We used …
binding proteins at specific sites to enhance or silence splicing at nearby splice sites. We used …
