Chip floorplanning is the engineering task of designing the physical layout of a computer
chip. Despite five decades of research 1, chip floorplanning has defied automation, requiring …

Background and aims The COVID-19 spreads rapidly around the world which has brought a
global health crisis. The pathogen of COVID-19 is SARS-COV-2, and previous studies have …

The latest 5G mobile networks have enabled many exciting Internet of Things (IoT) applications
that employ unmanned aerial vehicles (UAVs/drones). The success of most UAV-based …

Over the past decade, 3D concrete printing has shown enormous application potential for
the industry. The new technology poses specific requirements on 3D printable concrete (3DPC)…

Proteins in the Bcl-2 family are central regulators of programmed cell death 1 , and members
that inhibit apoptosis, such as Bcl-X L and Bcl-2, are overexpressed in many cancers and …

Obesity and type II diabetes are closely linked metabolic syndromes that afflict >100 million
people worldwide. Although protein tyrosine phosphatase 1B (PTP1B) has emerged as a …

4D-QSAR analysis incorporates conformational and alignment freedom into the development
of 3D-QSAR models for training sets of structure−activity data by performing ensemble …

The antiapoptotic proteins Bcl-x L and Bcl-2 play key roles in the maintenance of normal
cellular homeostasis. However, their overexpression can lead to oncogenic transformation and …

The p38 mitogen-activated protein kinases (MAPK) are activated by cellular stresses and
play an important role in regulating gene expression. We have isolated a cDNA encoding a …

This paper describes a plate recognition system that can process images rapidly at high
accuracy rates. This system is designed to meet the requirements of performance, …