Next-generation probiotics for inflammatory bowel disease

…, A Del Re, J Lu, I Palenca, C Corpetti, S Rurgo… - International Journal of …, 2022 - mdpi.com
Engineered probiotics represent a cutting-edge therapy in intestinal inflammatory disease (IBD).
Genetically modified bacteria have provided a new strategy to release therapeutically …

Cannabidiol inhibits SARS‐Cov‐2 spike (S) protein‐induced cytotoxicity and inflammation through a PPARγ‐dependent TLR4/NLRP3/Caspase‐1 signaling …

…, A Del Re, L Seguella, I Palenca, S Rurgo… - Phytotherapy …, 2021 - Wiley Online Library
Given the abundancy of angiotensin converting enzyme 2 (ACE‐2) receptors density, beyond
the lung, the intestine is considered as an alternative site of infection and replication for …

Nutraceuticals and diet supplements in Crohn's disease: A general overview of the most promising approaches in the clinic

…, M Pesce, M Chiurazzi, M Andreozzi, S Rurgo… - Foods, 2022 - mdpi.com
Crohn’s disease (CD) is a chronic inflammatory gastrointestinal disorder requiring lifelong
medications. The currently approved drugs for CD are associated with relevant side effects …

Ultramicronized palmitoylethanolamide inhibits NLRP3 inflammasome expression and pro-inflammatory response activated by SARS-CoV-2 spike protein in cultured …

…, M Pesce, L Seguella, L Steardo, I Palenca, S Rurgo… - Metabolites, 2021 - mdpi.com
Despite its possible therapeutic potential against COVID-19, the exact mechanism(s) by
which palmitoylethanolamide (PEA) exerts its beneficial activity is still unclear. PEA has …

Sleeve gastrectomy-induced body mass index reduction increases the intensity of taste perception's and reduces bitter-induced pleasantness in severe obesity

S Rurgo, E Cantone, M Pesce, E Efficie… - Journal of Clinical …, 2022 - mdpi.com
Background: The sense of taste is involved in food behavior and may drive food choices,
likely contributing to obesity. Differences in taste preferences have been reported in normal-…

N-palmitoyl-D-glucosamine inhibits TLR-4/NLRP3 and improves DNBS-induced colon inflammation through a PPAR-α-dependent mechanism

…, A Del Re, SB Franzin, C Corpetti, M Pesce, S Rurgo… - Biomolecules, 2022 - mdpi.com
Similar to canine inflammatory enteropathy, inflammatory bowel disease (IBD) is a chronic
idiopathic condition characterized by remission periods and recurrent flares in which diarrhea, …

Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice

…, S Basili Franzin, L Seguella, I Palenca, S Rurgo… - Biomolecules, 2023 - mdpi.com
As of October 2022, the COVID-19 pandemic continues to pose a major public health
conundrum, with increased rates of symptomatic infections in vaccinated individuals. An ideal …

Predictors of abdominal pain severity in patients with constipation-prevalent irritable bowel syndrome

S Rurgo, V Vaino, M Andreozzi, M Pagliaro… - Journal of Basic and …, 2022 - degruyter.com
Background Symptoms of irritable bowel syndrome (IBS) have been associated to altered
colonic motility and sensation. Smoking affects pain perception and is a risk factor in the …

Laparoscopic Heller-Dor myotomy in elderly achalasia patients: a single center experience with PSM analysis

…, F Pegoraro, R Basile, M Pesce, S Rurgo… - … Invasive Therapy & …, 2024 - Taylor & Francis
Introduction Achalasia is a rare esophageal motility disorder of unknown etiology. With the
ageing of the general population, treatment in elderly patients has become increasingly …

Patients with Diverticular Disease Have Different Dietary Habits Compared to Control Subjects: Results from an Observational Italian Study

B Polese, M Carabotti, S Rurgo, C Ritieni, G Sarnelli… - Nutrients, 2023 - mdpi.com
The role of dietary habits as risk factor for the development of diverticular complications has
strongly emerged in the last years. We aimed to evaluate possible differences in dietary …