Patient-derived xenografts (PDX) are an increasingly valuable tool in oncology, providing
biologically faithful models of many different cancer types, and potential platforms for the …

The chick chorioallantoic membrane (CAM) begins to develop by day 7 after fertilization and
matures by day 12. The CAM is naturally immunodeficient and highly vascularized, making …

The genome-wide role of heterotrimeric G-proteins in abiotic stress response in rice has not
been examined from a functional genomics perspective, despite the availability of mutants …

Gaucher disease (GD) is an autosomal recessive inherited lysosomal storage disease that
often presents in early childhood and is associated with damage to multiple organ systems. …

Autologous cell transplantation holds enormous promise to restore organ and tissue
functions in the treatment of various pathologies including endocrine, cardiovascular, and …

The biochemical landscape of lysine acetylation has expanded from a small number of proteins
in the nucleus to a multitude of proteins in the cytoplasm. Since the first report confirming …

The controversy over the existence or the need for G-protein coupled receptors (GPCRs) in
plant G-protein signalling has overshadowed a more fundamental quest for the role of …

Tumor immune microenvironment and tumor metabolism are major determinants of
chemoradiotherapy response. The interdependency and prognostic significance of specific immune …

Objectives/Hypothesis Characterization of the localized adaptive immune response in the
airway scar of patients with idiopathic subglottic stenosis (iSGS). Study Design Basic Science. …

Mucopolysaccharidosis type II (MPS II; Hunter syndrome) is a rare, X-linked disorder caused
by deficient activity of the enzyme iduronate-2-sulfatase. Signs and symptoms typically …