User profiles for Mithun Rudrapal

Mithun Rudrapal

Associate Professor, Vignan's Foundation for Science, Technology and Research
Verified email at vignan.ac.in
Cited by 3742

Dietary polyphenols and their role in oxidative stress-induced human diseases: Insights into protective effects, antioxidant potentials and mechanism (s) of action

M Rudrapal, SJ Khairnar, J Khan, AB Dukhyil… - Frontiers in …, 2022 - frontiersin.org
Dietary polyphenols including phenolic acids, flavonoids, catechins, tannins, lignans, stilbenes,
and anthocyanidins are widely found in grains, cereals, pulses, vegetables, spices, fruits, …

[HTML][HTML] Repurposing of phytomedicine-derived bioactive compounds with promising anti-SARS-CoV-2 potential: Molecular docking, MD simulation and drug-likeness …

M Rudrapal, N Gogoi, D Chetia, J Khan… - Saudi journal of …, 2022 - Elsevier
In view of the potential of traditional plant-based remedies (or phytomedicines) in the
management of COVID-19, the present investigation was aimed at finding novel anti-SARS-CoV-2 …

Dietary flavonoids: Cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns

…, S Priya, KD Medina, R Devi, SG Walode, M Rudrapal - Molecules, 2021 - mdpi.com
Flavonoids comprise a large group of structurally diverse polyphenolic compounds of plant
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …

Bioactive compounds effective against type 2 diabetes mellitus: a systematic review

…, CG Awuchi, G Kushwaha, M Rudrapal… - Current Topics in …, 2021 - ingentaconnect.com
Background: Type 2 diabetes (adult onset diabetes) is the most common type of diabetes,
accounting for around 90% of all diabetes cases with insulin resistance and insulin secretion …

Coronavirus disease-2019 (COVID-19): an updated review

M Rudrapal, SJ Khairnar, LB Borse… - Drug research, 2020 - thieme-connect.com
The current outbreak of novel Coronavirus Disease-2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major pandemic situation and a …

Chalcone scaffolds, bioprecursors of flavonoids: Chemistry, bioactivities, and pharmacokinetics

M Rudrapal, J Khan, AAB Dukhyil, RMII Alarousy… - Molecules, 2021 - mdpi.com
Chalcones are secondary metabolites belonging to the flavonoid (C 6 -C 3 -C 6 system)
family that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …

Drug repurposing (DR): an emerging approach in drug discovery

M Rudrapal, SJ Khairnar, AG Jadhav - … , molecular aspects and …, 2020 - books.google.com
Drug repurposing (DR)(also known as drug repositioning) is a process of identifying new
therapeutic use (s) for old/existing/available drugs. It is an effective strategy in discovering or …

Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies

M Rudrapal, WA Eltayeb, G Rakshit, AA El-Arabey… - Scientific Reports, 2023 - nature.com
Cyclooxygenase (COX) and Lipoxygenase (LOX) are essential enzymes for arachidonic acid
(AA) to eicosanoids conversion. These AA-derived eicosanoids are essential for initiating …

Nanodelivery of dietary polyphenols for therapeutic applications

M Rudrapal, AK Mishra, L Rani, KK Sarwa… - Molecules, 2022 - mdpi.com
Advancement in nanotechnology has unleashed the therapeutic potentials of dietary
polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific …

[HTML][HTML] Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through …

M Rudrapal, I Celik, J Khan, MA Ansari… - Journal of King Saud …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus
disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The …