MicroRNAs—the micro steering wheel of tumour metastases
Recently, microRNAs (miRNAs) have been discovered to have a role in metastasis. Here
we describe how miRNAs are involved in advanced stages of tumour progression, stressing …
we describe how miRNAs are involved in advanced stages of tumour progression, stressing …
Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility
Single-nucleotide polymorphisms (SNP) associated with polygenetic disorders, such as
breast cancer (BC), can create, destroy, or modify microRNA (miRNA) binding sites; however, …
breast cancer (BC), can create, destroy, or modify microRNA (miRNA) binding sites; however, …
A microRNA DNA methylation signature for human cancer metastasis
…, S Rossi, MS Nicoloso… - Proceedings of the …, 2008 - National Acad Sciences
MicroRNAs (miRNAs) are small, noncoding RNAs that can contribute to cancer development
and progression by acting as oncogenes or tumor suppressor genes. Recent studies have …
and progression by acting as oncogenes or tumor suppressor genes. Recent studies have …
E2F1-regulated microRNAs impair TGFβ-dependent cell-cycle arrest and apoptosis in gastric cancer
…, R Visone, MR Onelli, MH Shah, MS Nicoloso… - Cancer cell, 2008 - cell.com
Deregulation of E2F1 activity and resistance to TGFβ are hallmarks of gastric cancer. MicroRNAs
(miRNAs) are small noncoding RNAs frequently misregulated in human malignancies. …
(miRNAs) are small noncoding RNAs frequently misregulated in human malignancies. …
MicroRNA Fingerprints Identify miR-150 as a Plasma Prognostic Marker in Patients with Sepsis
Background The physiopathology of sepsis continues to be poorly understood, and despite
recent advances in its management, sepsis is still a life-threatening condition with a poor …
recent advances in its management, sepsis is still a life-threatening condition with a poor …
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia
Context Chromosomal abnormalities (namely 13q, 17p, and 11q deletions) have prognostic
implications and are recurrent in chronic lymphocytic leukemia (CLL), suggesting that they …
implications and are recurrent in chronic lymphocytic leukemia (CLL), suggesting that they …
SnapShot: microRNAs in cancer
SNP in K-RAS 3′ UTR (let-7a binding site) increases NSCLC risk (cancer predisposition).
Low expression of let-7a-2 in lung and ovarian cancer and of let-7b in uveal melanoma (poor …
Low expression of let-7a-2 in lung and ovarian cancer and of let-7b in uveal melanoma (poor …
p27Kip1-stathmin interaction influences sarcoma cell migration and invasion
G Baldassarre, B Belletti, MS Nicoloso… - Cancer cell, 2005 - cell.com
Emerging evidences suggest that cyclin-dependent kinase inhibitors (CKIs) can regulate
cellular functions other than cell cycle progression, such as differentiation and migration. Here, …
cellular functions other than cell cycle progression, such as differentiation and migration. Here, …
Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells
BACKGROUND & AIMS: MicroRNAs (miRNAs) can promote or inhibit tumor growth and are
therefore being developed as targets for cancer therapies. They are diverse not only in the …
therefore being developed as targets for cancer therapies. They are diverse not only in the …
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival
…, M Shimizu, E Barbarotto, MS Nicoloso… - Blood, The Journal …, 2010 - ashpublications.org
Aberrant expression of microRNAs (miRNAs) has been associated with clinical outcome in
patients with chronic lymphocytic leukemia (CLL). To identify a powerful and easily …
patients with chronic lymphocytic leukemia (CLL). To identify a powerful and easily …