[HTML][HTML] The Evolving Role of Bruton's Tyrosine Kinase Inhibitors in B Cell Lymphomas

S Mehra, M Nicholls, J Taylor - International Journal of Molecular …, 2024 - mdpi.com
Bruton’s tyrosine kinase (BTK), a non-receptor tyrosine kinase crucial for B cell development
and function, acts downstream of the B cell receptor (BCR) in the BCR pathway. Other …

Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition

…, AK Sondhi, S Noudali, AM Cornista, M Nicholls… - Leukemia, 2024 - nature.com
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of
XPO1 inhibitors, selinexor and eltanexor, in high-risk myelodysplastic neoplasms (MDS) …

Potent, Selective, and Orally Bioavailable Quinazoline-Based STK17A/B Dual Inhibitors

…, J Afaghani, R Khurshid, M Nicholls… - ACS medicinal …, 2024 - ACS Publications
STK17A is a novel uncharacterized member of the death-associated protein family of serine
and threonine kinases. Overexpression of STK17A is observed in many cancers. We …

[PDF][PDF] The effects of helicopter noise on perceived tranquillity in New Zealand national parks.

H Nicholls - 2017 - ir.canterbury.ac.nz
This study aimed to review methods of subjective tranquillity testing, which were then
applied to the New Zealand population. This was done in order to determine the relationship …

[BOOK][B] Help to the Reading of the Bible

BE Nicholls - 1853 - books.google.com
… The present work was written by the late Benjamin Elliot Nicholls, MA, of Queen's College,
Cambridge, (Eng.,) and was originally published by the (London) "Society for Promoting …

SARS-CoV-2 within-host diversity and transmission

…, R Williams, G Vernet, A Justice, A Green, SM Nicholls… - Science, 2021 - science.org
INTRODUCTION Genome sequencing at an unprecedented scale during the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is helping to track spread of the …

Targeting reactive oxygen species (ROS) to combat the age-related loss of muscle mass and function

A Thoma, T Akter-Miah, RL Reade, AP Lightfoot - Biogerontology, 2020 - Springer
The loss of muscle mass and function with age, termed sarcopenia, is an inevitable process,
which has a significant impact on quality of life. During ageing we observe a progressive …

[BOOK][B] Dictionary of national biography

ET Williams, CS Nicholls, R Blake, HM Palmer… - 1903 - books.google.com
THIS Volume was designed by the late Mr. George Smith, the proprietor and publisher of the'Dictionary
of National Biography,'in consultation with the present Editor, when the great …

Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic

…, V Hill, A Lucaci, JT McCrone, SM Nicholls… - Cell, 2021 - cell.com
We present evidence for multiple independent origins of recombinant SARS-CoV-2 viruses
sampled from late 2020 and early 2021 in the United Kingdom. Their genomes carry single-…

Relationships between human disturbance and wildlife land use in urban habitat fragments

L Markovchick‐Nicholls, HM Regan… - Conservation …, 2008 - Wiley Online Library
Habitat remnants in urbanized areas typically conserve biodiversity and serve the recreation
and urban open‐space needs of human populations. Nevertheless, these goals can be in …