Glioblastoma multiforme ( GBM ) is treated by surgical resection followed by radiochemotherapy.
Bevacizumab is commonly deployed for anti‐angiogenic therapy of recurrent GBM ; …

Background Autopsies are an important tool in medicine, dissecting disease pathophysiology
and causes of death. In COVID-19, autopsies revealed eg, the effects on pulmonary (micro…

The activation of immune cells by targeting checkpoint inhibitors showed promising results
with increased patient survival in distinct primary cancers. Since only limited data exist for …

Background Recent studies have reported mutations in the telomerase reverse transcriptase
promoter (TERTp) in meningiomas. We sought to determine the frequency, clonality and …

Our understanding of metastatic spread is limited and molecular mechanisms causing
particular characteristics of metastasis are largely unknown. Herein, transcriptome‐wide …

Glioblastoma (GBM) is a non-T-cell–inflamed cancer characterized by an immunosuppressive
microenvironment that impedes dendritic cell maturation and T-cell cytotoxicity. …

Escherichia coli hemolysin (HlyA) and Staphylococcus aureus alpha-toxin are membrane-perturbating
bacterial exotoxins that have been implicated as significant virulence factors in …

PURPOSE The HIT-2000-BIS4 trial aimed to avoid highly detrimental craniospinal irradiation
(CSI) in children < 4 years of age with nonmetastatic medulloblastoma by systemic …

Currently used clinicopathological parameters are insufficient for a reliable prediction of
metastatic risk and disease‐free survival (DFS) of patients with clear‐cell renal cell carcinoma (…

Progressive meningiomas that have failed surgery and radiation have a poor prognosis and
no standard therapy. While meningiomas are more common in females overall, progressive …