Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype
…, P Sauvanet, C Darcha, P Déchelotte, M Bonnet… - Gut, 2014 - gut.bmj.com
Background Escherichia coli strains harbouring the pks island (pks+ E. coli) are often seen
in human colorectal tumours and have a carcinogenic effect independent of inflammation in …
in human colorectal tumours and have a carcinogenic effect independent of inflammation in …
Detection of Epstein-Barr virus in invasive breast cancers
M Bonnet, JM Guinebretiere, E Kremmer… - Journal of the …, 1999 - academic.oup.com
BACKGROUND: Epstein-Barr virus (EBV) may be a cofactor in the development of different
malignancies, including several types of carcinomas. In this study, we investigated the …
malignancies, including several types of carcinomas. In this study, we investigated the …
[HTML][HTML] Microbial markers in colorectal cancer detection and/or prognosis
…, N Barnich, E Billard, D Boucher, M Bonnet - World journal of …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the second leading cause of cancer worldwide. CRC is still
associated with a poor prognosis among patients with advanced disease. On the contrary, due to …
associated with a poor prognosis among patients with advanced disease. On the contrary, due to …
[HTML][HTML] Gut microbiota imbalance and colorectal cancer
…, J Raisch, J Veziant, N Barnich, R Bonnet… - World journal of …, 2016 - ncbi.nlm.nih.gov
The gut microbiota acts as a real organ. The symbiotic interactions between resident micro-organisms
and the digestive tract highly contribute to maintain the gut homeostasis. However, …
and the digestive tract highly contribute to maintain the gut homeostasis. However, …
Colonization of the Human Gut by E. coli and Colorectal Cancer Risk
M Bonnet, E Buc, P Sauvanet, C Darcha, D Dubois… - Clinical Cancer …, 2014 - AACR
Purpose: The intestinal microbiota is potentially involved in the development of colorectal
carcinoma via various mechanisms. Escherichia coli are commensal bacteria of the human gut …
carcinoma via various mechanisms. Escherichia coli are commensal bacteria of the human gut …
Intestinal microbiota: a novel target to improve anti-tumor treatment?
…, N Barnich, J Gagnière, E Vazeille, M Bonnet - International journal of …, 2019 - mdpi.com
Recently, preclinical and clinical studies targeting several types of cancer strongly
supported the key role of the gut microbiota in the modulation of host response to anti-tumoral …
supported the key role of the gut microbiota in the modulation of host response to anti-tumoral …
[HTML][HTML] Colon cancer-associated B2 Escherichia coli colonize gut mucosa and promote cell proliferation
J Raisch, E Buc, M Bonnet, P Sauvanet… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To provide further insight into the characterization of mucosa-associated Escherichia coli
(E. coli) isolated from the colonic mucosa of cancer patients. METHODS: Phylogroups and …
(E. coli) isolated from the colonic mucosa of cancer patients. METHODS: Phylogroups and …
Colibactin‐positive Escherichia coli induce a procarcinogenic immune environment leading to immunotherapy resistance in colorectal cancer
…, N Barnich, B Dumas, M Bonnet - … Journal of Cancer, 2020 - Wiley Online Library
Colibactin‐producing E. coli (CoPEC) are frequently detected in colorectal cancer (CRC) and
exhibit procarcinogenic properties. Because increasing evidence show the role of immune …
exhibit procarcinogenic properties. Because increasing evidence show the role of immune …
Autophagy of intestinal epithelial cells inhibits colorectal carcinogenesis induced by colibactin-producing Escherichia coli in ApcMin/+ mice
Background & Aims Colibactin-producing Escherichia coli (CoPEC) colonize the colonic
mucosa of a higher proportion of patients with vs without colorectal cancer (CRC) and promote …
mucosa of a higher proportion of patients with vs without colorectal cancer (CRC) and promote …
AhR/IL-22 pathway as new target for the treatment of post-infectious irritable bowel syndrome symptoms
…, JM Chatel, P Langella, V Livrelli, M Bonnet… - Gut …, 2022 - Taylor & Francis
Alterations in brain/gut/microbiota axis are linked to Irritable Bowel Syndrome (IBS)
physiopathology. Upon gastrointestinal infection, chronic abdominal pain and anxio-depressive …
physiopathology. Upon gastrointestinal infection, chronic abdominal pain and anxio-depressive …