Overexpression of lysophosphatidylcholine acyltransferase 1 and concomitant lipid alterations in gastric cancer

…, I Iino, T Setoguchi, Y Hiramatsu, M Ohta… - Annals of surgical …, 2016 - Springer
Background The involvement of lipids in carcinogenic and developmental processes has been
reported in some malignancies, but their roles in gastric cancer remain to be analyzed. In …

TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche

M Yamamoto, H Kikuchi, M Ohta, T Kawabata… - Cancer …, 2008 - aacrjournals.org
The aim of this study was to investigate the inhibitory effect of TSU68 [(Z)-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic
acid; SU6668], an …

Effect of mi R‐122 and its target gene cationic amino acid transporter 1 on colorectal liver metastasis

…, H Kikuchi, S Miyazaki, Y Hiramatsu, M Ohta… - Cancer …, 2013 - Wiley Online Library
Control of liver metastasis is an important issue in the treatment of colorectal cancer ( CRC ).
Micro RNA s have been shown to be involved in the development of many cancers, but little …

Quantitative assessment of the free jejunal graft perfusion

…, M Sano, H Kikuchi, Y Hiramatsu, M Ohta… - Journal of Surgical …, 2015 - Elsevier
Background Reconstruction with free jejunal graft (FJG) is often performed for patients with
hypopharyngeal or cervical esophageal cancer. During reconstruction with an FJG after …

Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury

M Ohta, Y Higashi, T Yawata, M Kitahara, A Nobumoto… - Brain research, 2013 - Elsevier
Traumatic axonal injury (TAI), a feature of traumatic brain injury (TBI), progressively evolves
over hours through impaired axonal transport and is thought to be a major contributor to …

Tenascin C in colorectal cancer stroma is a predictive marker for liver metastasis and is a potent target of miR-198 as identified by microRNA analysis

…, Y Ozaki, T Kawabata, Y Hiramatsu, M Ohta… - British journal of …, 2017 - nature.com
Background: Tumour stroma has important roles in the development of colorectal cancer (CRC)
metastasis. We aimed to clarify the roles of microRNAs (miRNAs) and their target genes …

The role of circulating IL‐8 and VEGF protein in the progression of gastric cancer

H Konno, M Ohta, M Baba, S Suzuki… - Cancer …, 2003 - Wiley Online Library
Both vascular endothelial growth factor (VEGF) and interleukin 8 (IL‐8) play an important role
in the progression of gastric cancer (GC). In this study, we investigated whether circulating …

Anti‐VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts

…, T Fujita, Y Hiramatsu, M Ohta… - … journal of cancer, 2014 - Wiley Online Library
Tumor angiogenesis plays a critical role in colorectal cancer progression. Recent randomized
clinical trials have revealed the additive effect of bevacizumab, a humanized monoclonal …

Peritoneal metastasis as a predictive factor for nab-paclitaxel in patients with pretreated advanced gastric cancer: an exploratory analysis of the phase III ABSOLUTE …

…, M Goto, N Fukushima, T Hara, N Machida, M Ohta… - Gastric Cancer, 2019 - Springer
Background In the ABSOLUTE trial, weekly nanoparticle albumin-bound paclitaxel (w-nab-PTX)
showed non-inferiority to weekly solvent-based paclitaxel (w-sb-PTX) for overall survival …

The significance of circulating vascular endothelial growth factor (VEGF) protein in gastric cancer

M Ohta, H Konno, T Tanaka, M Baba, K Kamiya… - Cancer letters, 2003 - Elsevier
We examined the vascular endothelial growth factor (VEGF) levels in peripheral blood and
drainage vein (plasma and serum), and then these were compared with local VEGF …