User profiles for Lei Qu

Lei Qu

Anhui University
Verified email at ahu.edu.cn
Cited by 3041

BrainAligner: 3D registration atlases of Drosophila brains

H Peng, P Chung, F Long, L Qu, A Jenett, AM Seeds… - Nature …, 2011 - nature.com
Analyzing Drosophila melanogaster neural expression patterns in thousands of three-dimensional
image stacks of individual brains requires registering them into a canonical …

Direct Universal Access: Making Data Center Resources Available to {FPGA}

R Shu, P Cheng, G Chen, Z Guo, L Qu… - … USENIX Symposium on …, 2019 - usenix.org
FPGAs have been deployed at massive scale in data centers. The currently available
communication architectures, however, make FPGAs very difficult to utilize resources in data center…

LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling

J Yang, F Liu, Y Wang, L Qu, A Lin - Cancer Letters, 2022 - Elsevier
Evidence accumulated over the past decade has verified that long non-coding RNAs (lncRNAs)
exert important functions in multiple cell programs. As a novel class of cellular regulatory …

[HTML][HTML] A GAL4-driver line resource for Drosophila neurobiology

…, P Hulamm, SCB Lam, HH Li, TR Laverty, F Long, L Qu… - Cell reports, 2012 - cell.com
We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression
of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that …

Iron metabolism, ferroptosis, and lncRNA in cancer: knowns and unknowns

L Qu, X He, Q Tang, X Fan, J Liu, A Lin - Journal of Zhejiang University …, 2022 - Springer
Cancer cells undergo substantial metabolic alterations to sustain increased energy supply
and uncontrolled proliferation. As an essential trace element, iron is vital for many biological …

Morphological diversity of single neurons in molecularly defined cell types

H Peng, P Xie, L Liu, X Kuang, Y Wang, L Qu, H Gong… - Nature, 2021 - nature.com
Dendritic and axonal morphology reflects the input and output of neurons and is a defining
feature of neuronal types 1 , 2 , yet our knowledge of its diversity remains limited. Here, to …

LncRNAs: architectural scaffolds or more potential roles in phase separation

J Luo, L Qu, F Gao, J Lin, J Liu, A Lin - Frontiers in Genetics, 2021 - frontiersin.org
Biomolecules specifically aggregate in the cytoplasm and nucleus, driving liquid-liquid
phase separation (LLPS) formation and diverse biological processes. Extensive studies have …

3-D registration of biological images and models: registration of microscopic images and its uses in segmentation and annotation

L Qu, F Long, H Peng - IEEE Signal Processing Magazine, 2014 - ieeexplore.ieee.org
The registration, segmentation, and annotation of microscopy images and respective
biological objects (eg, cells) are distinct challenges often encountered in bioimage informatics. …

Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

X Wang, H Yu, A Lei, J Zhou, W Zeng, H Zhu, Z Dong… - Scientific reports, 2015 - nature.com
Recent advances in the study of the CRISPR/Cas9 system have provided a precise and
versatile approach for genome editing in various species. However, the applicability and …

Cross-modal coherent registration of whole mouse brains

L Qu, Y Li, P Xie, L Liu, Y Wang, J Wu, Y Liu, T Wang… - Nature …, 2022 - nature.com
Recent whole-brain mapping projects are collecting large-scale three-dimensional images
using modalities such as serial two-photon tomography, fluorescence micro-optical …