User profiles for Laura M. Cox

Laura Cox

Harvard Medical School
Verified email at bwh.harvard.edu
Cited by 12254

[HTML][HTML] Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences

LM Cox, S Yamanishi, J Sohn, AV Alekseyenko… - Cell, 2014 - cell.com
Acquisition of the intestinal microbiota begins at birth, and a stable microbial community
develops from a succession of key organisms. Disruption of the microbiota during maturation by …

Pathways in microbe-induced obesity

LM Cox, MJ Blaser - Cell metabolism, 2013 - cell.com
Diet, host gene composition, and alterations in the intestinal microbiota can contribute to
obesity. In microbe-induced obesity, metabolic changes stem from primary perturbation of the …

Antibiotics in early life and obesity

LM Cox, MJ Blaser - Nature Reviews Endocrinology, 2015 - nature.com
The intestinal microbiota can influence host metabolism. When given early in life, agents that
disrupt microbiota composition, and consequently the metabolic activity of the microbiota, …

Gut microbiome in progressive multiple sclerosis

LM Cox, AH Maghzi, S Liu, SK Tankou… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to investigate the gut microbiome in progressive
multiple sclerosis (MS) and how it relates to clinical disease. Methods We sequenced the …

Alterations of the human gut microbiome in multiple sclerosis

S Jangi, R Gandhi, LM Cox, N Li, F Von Glehn… - Nature …, 2016 - nature.com
The gut microbiome plays an important role in immune function and has been implicated in
several autoimmune disorders. Here we use 16S rRNA sequencing to investigate the gut …

Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer

…, KM De Jesus-Laboy, N Shen, LM Cox… - Nature medicine, 2016 - nature.com
Exposure of newborns to the maternal vaginal microbiota is interrupted with cesarean birthing.
Babies delivered by cesarean section (C-section) acquire a microbiota that differs from …

Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course

…, X Gao, M Mendoza, S Singh, IK Sand, Z Xia, LM Cox… - Cell, 2022 - cell.com
Changes in gut microbiota have been associated with several diseases. Here, the International
Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of 576 MS …

Helminth colonization is associated with increased diversity of the gut microbiota

…, YAL Lim, SH Choy, ZD Kurtz, LM Cox… - PLoS neglected …, 2014 - journals.plos.org
Soil-transmitted helminths colonize more than 1.5 billion people worldwide, yet little is known
about how they interact with bacterial communities in the gut microbiota. Differences in the …

Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment

YR Nobel, LM Cox, FF Kirigin, NA Bokulich… - Nature …, 2015 - nature.com
Mammalian species have co-evolved with intestinal microbial communities that can shape
development and adapt to environmental changes, including antibiotic perturbation or …

[HTML][HTML] Microbiota signaling pathways that influence neurologic disease

LM Cox, HL Weiner - Neurotherapeutics, 2018 - Elsevier
Though seemingly distinct and autonomous, emerging evidence suggests there is a bidirectional
interaction between the intestinal microbiota and the brain. This crosstalk may play a …