Extracorporeal membrane oxygenation support for complex tracheo-bronchial procedures

G Lang, B Ghanim, K Hötzenecker… - European Journal of …, 2015 - academic.oup.com
OBJECTIVES The published experience with advanced broncho-plastic procedures
performed with extracorporeal membrane oxygenation (ECMO) support is very limited. We …

The serine proteases dipeptidyl-peptidase 4 and urokinase are key molecules in human and mouse scar formation

…, C Radtke, E Tschachler, K Hötzenecker… - Nature …, 2021 - nature.com
Despite recent advances in understanding skin scarring, mechanisms triggering hypertrophic
scar formation are still poorly understood. In the present study, we investigate mature …

Tumour immune microenvironment in resected thymic carcinomas as a predictor of clinical outcome

…, C Veraar, W Klepetko, K Hötzenecker… - British Journal of …, 2022 - nature.com
Background The spatial distribution of tumour-infiltrating lymphocytes (TILs) is a novel descriptor
characterising the tumour immune microenvironment (TIME). The aim of our study was …

Lungs preserved on ice or in a refrigerator? Prolonged static lung storage at 10° C

M Cypel, K Hötzenecker… - The Annals of …, 2023 - annalsthoracicsurgery.org
The lung transplant (LTx) community was excited by reports from the University of Toronto of
successful LTxs with seemingly improved perioperative outcomes, compared with standard-…

[HTML][HTML] Real-World Treatment Patterns and Timeliness of Clinical Care Pathway for Non-Small Cell Lung Cancer Patients in Austria: The PRATER Retrospective …

…, B Baumgartner, P Schenk, M Rauter, K Hötzenecker - Cancers, 2024 - mdpi.com
Simple Summary Non-small cell lung cancer (NSCLC) is the most common form of lung
cancer. Treatments and outcomes for NSCLC are evolving as a result of multiple approvals for …

Donation after cardiac death, a possibility to expand the donor pool: review and the hungarian experience

…, G Lang, S Taghavi, K Hötzenecker… - Transplantation …, 2019 - Elsevier
Introduction Lung transplantation is the only successful treatment option for patients
experiencing end-stage lung disease. Results have improved significantly in the last decade; …

Use of Recombinant Activated Factor VII in Bleeding Lung Transplant Patients Undergoing Perioperative ECMO Therapy

…, E Schaden, M Wiegele, K Hötzenecker… - Journal of Clinical …, 2023 - mdpi.com
Background: Hemostasis in critically ill patients represents a fragile balance between
hypocoagulation and hypercoagulation, and is influenced by various factors. Perioperative use of …

[HTML][HTML] Lipidomics for diagnosis and prognosis of pulmonary hypertension

…, BA Maron, S Ulrich, TJ Lange, K Hötzenecker… - medRxiv, 2023 - ncbi.nlm.nih.gov
Background Pulmonary hypertension (PH) poses a significant health threat with high
morbidity and mortality, necessitating improved diagnostic tools for enhanced management. …

Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in ex vivo precision cut lung slices from patients with Idiopathic …

…, AL Coelho, M Espindola, C Ruppert, K Hötzenecker… - bioRxiv, 2024 - biorxiv.org
Rationale: While rodent lung fibrosis models are routinely used to evaluate novel antifibrotics,
these models have largely failed to predict clinical efficacy of novel drug candidates for …

Lung surgery and extracorporeal membrane oxygenation

S Taghavi, A Benazzo, K Hötzenecker… - Cardiopulmonary …, 2023 - Elsevier
Extracorporeal life support (ECLS) has revolutionized thoracic surgery since its first use in
clinical practice half a century ago. Thanks to ECLS, complex resections and reconstructions …