User profiles for Kenji Ohshima

Kenji Ohshima

Hyogo Medical University, Department of Molecular Pathology
Verified email at hyo-med.ac.jp
Cited by 1030

DWARF10, an RMS1/MAX4/DAD1 ortholog, controls lateral bud outgrowth in rice

T Arite, H Iwata, K Ohshima, M Maekawa… - The Plant …, 2007 - Wiley Online Library
Plant architecture is mostly determined by shoot branching patterns. Apical dominance is a
well‐known control mechanism in the development of branching patterns, but little is known …

[HTML][HTML] Metabolic reprogramming of cancer cells during tumor progression and metastasis

K Ohshima, E Morii - Metabolites, 2021 - mdpi.com
Cancer cells face various metabolic challenges during tumor progression, including growth
in the nutrient-altered and oxygen-deficient microenvironment of the primary site, …

Density and maturity of peritumoral tertiary lymphoid structures in oesophageal squamous cell carcinoma predicts patient survival and response to immune checkpoint …

Y Hayashi, T Makino, E Sato, K Ohshima… - British Journal of …, 2023 - nature.com
Background Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates in non-lymphoid
tissues, which are associated with improved prognosis in some cancer types. This …

CUBIC pathology: three-dimensional imaging for pathological diagnosis

…, K Takachi, Y Nakahara, S Tahara, K Ohshima… - Scientific reports, 2017 - nature.com
The examination of hematoxylin and eosin (H&E)-stained tissues on glass slides by
conventional light microscopy is the foundation for histopathological diagnosis. However, this …

Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling

K Moriwaki, K Noda, Y Furukawa, K Ohshima… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
promotes apoptosis in cancer cells, but not normal cells, and is critically involved in tumor …

Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine

K Ohshima, S Nojima, S Tahara, M Kurashige… - Nature …, 2020 - nature.com
Serine racemase (SRR) catalyses not only the racemization but also the dehydration of l-serine
and d-serine, resulting in the formation of pyruvate and ammonia. Although SRR activity …

FAM111B enhances proliferation of KRAS‐driven lung adenocarcinoma by degrading p16

…, S Nojima, S Hijiki, S Tahara, K Ohshima… - Cancer …, 2020 - Wiley Online Library
Lung cancer is a common type of cancer that represents a health problem worldwide; lung
adenocarcinoma (LUAD) is a major subtype of lung cancer. Although several treatments for …

Origin of cancer-associated fibroblasts and tumor-associated macrophages in humans after sex-mismatched bone marrow transplantation

M Kurashige, M Kohara, K Ohshima, S Tahara… - Communications …, 2018 - nature.com
Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) in tumor
stroma play a key role in disease progression. Recent studies using mice models suggest …

Immunoscore signatures in surgical specimens and tumor-infiltrating lymphocytes in pretreatment biopsy predict treatment efficacy and survival in esophageal cancer

T Noma, T Makino, K Ohshima, K Sugimura… - Annals of …, 2023 - journals.lww.com
Objectives: Tumor-infiltrating lymphocytes (TILs) have long been recognized as playing an
important role in tumor immune microenvironment. Lately, the Immunoscore (IS) has been …

Purification and Characterization of Exo-β-d-Glucosaminidase from a Cellulolytic Fungus,Trichoderma reesei PC-3-7

…, H Takahashi, A Kashiwagi, K Ohshima… - Applied and …, 1998 - journals.asm.org
Chitosan-degrading activities induced by glucosamine (GlcN) orN-acetylglucosamine (GlcNAc)
were found in a culture filtrate of Trichoderma reesei PC-3-7. One of the chitosan-…