Sequential therapy with supercharged NK cells with either chemotherapy drug cisplatin or anti-PD-1 antibody decreases the tumor size and significantly enhances the …
Introduction and methods In this study we report that sequential treatment of supercharged
NK (sNK) cells with either chemotherapeutic drugs or check-point inhibitors eliminate both …
NK (sNK) cells with either chemotherapeutic drugs or check-point inhibitors eliminate both …
[PDF][PDF] Anaemia 'a silent killer'among women in India: Present scenario
K Kaur - European Journal of Zoological Research, 2014 - academia.edu
Anaemia is the most prevalent nutritional deficiency disorder in the world. It affects all age
groups but the most vulnerable are preschool-age children, pregnant women, and non-…
groups but the most vulnerable are preschool-age children, pregnant women, and non-…
Osteoclasts and probiotics mediate significant expansion, functional activation and supercharging in NK, γδ T, and CD3+ T cells: use in cancer immunotherapy
Our previous studies have introduced osteoclasts (OCs) as major activators of NK cells. It was
found that OCs exhibit the capabilities of inducing cell expansion as well as increasing the …
found that OCs exhibit the capabilities of inducing cell expansion as well as increasing the …
Microplastic-associated pathogens and antimicrobial resistance in environment
The ubiquitous use of microplastics and their release into the environment especially the
water bodies by anthropogenic/industrial activities are the major resources for microplastic …
water bodies by anthropogenic/industrial activities are the major resources for microplastic …
The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro
The RNA-binding protein Hu antigen R (HuR) binds to AU-rich elements (ARE) in the 3’-untranslated
region (UTR) of target mRNAs. The HuR-ARE interactions stabilize many …
region (UTR) of target mRNAs. The HuR-ARE interactions stabilize many …
Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells
Osteoclasts (OCs) and much less dendritic cells (DCs) induce significant expansion and
functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially …
functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially …
Structure and biophysics of type III secretion in bacteria
Many plant and animal bacterial pathogens assemble a needle-like nanomachine, the type
III secretion system (T3SS), to inject virulence proteins directly into eukaryotic cells to initiate …
III secretion system (T3SS), to inject virulence proteins directly into eukaryotic cells to initiate …
Probiotic-treated super-charged NK cells efficiently clear poorly differentiated pancreatic tumors in Hu-BLT mice
Background and Aims: We have previously demonstrated that the stage of differentiation of
tumors has profound effect on the function of NK cells, and that stem-like/poorly differentiated …
tumors has profound effect on the function of NK cells, and that stem-like/poorly differentiated …
Novel strategy to expand super-charged NK cells with significant potential to lyse and differentiate cancer stem cells: differences in NK expansion and function …
K Kaur, J Cook, SH Park, P Topchyan… - Frontiers in …, 2017 - frontiersin.org
Natural killer (NK) cells are known to target cancer stem cells and undifferentiated tumors. In
this paper, we provide a novel strategy for expanding large numbers of super-charged NK …
this paper, we provide a novel strategy for expanding large numbers of super-charged NK …
ADCC against MICA/B is mediated against differentiated oral and pancreatic and not stem-like/poorly differentiated tumors by the NK cells; loss in cancer patients due …
Simple Summary Natural Killer cells are known to eliminate tumors directly or via antibody
dependent cellular cytotoxicity. The complete modes and mechanisms of such killings are yet …
dependent cellular cytotoxicity. The complete modes and mechanisms of such killings are yet …