Small-molecule inhibitor BMS-777607 induces breast cancer cell polyploidy with increased resistance to cytotoxic chemotherapy agents
S Sharma, JY Zeng, CM Zhuang, YQ Zhou… - Molecular cancer …, 2013 - aacrjournals.org
The RON receptor tyrosine kinase is a therapeutic target for cancer treatment. Here, we
report therapeutic effect and phenotypic change of breast cancer cells in response to BMS-…
report therapeutic effect and phenotypic change of breast cancer cells in response to BMS-…
Synergistic cementing efficiencies of nano-silica and micro-silica in carbonation resistance and sorptivity of concrete
Nano-silica (NS) and micro-silica (MS) are both effective in improving the strength and
durability of concrete, but their combined effect on a particular performance attribute may not be …
durability of concrete, but their combined effect on a particular performance attribute may not be …
Synergistic activities of MET/RON inhibitor BMS-777607 and mTOR inhibitor AZD8055 to polyploid cells derived from pancreatic cancer and cancer stem cells
JY Zeng, S Sharma, YQ Zhou, HP Yao… - Molecular cancer …, 2014 - aacrjournals.org
Tyrosine kinase inhibitor BMS-777067 is an inhibitor of RON/MET receptor tyrosine kinases
currently under clinical trials. Here, we report the synergistic activity of BMS-777607 in …
currently under clinical trials. Here, we report the synergistic activity of BMS-777607 in …
Physiological emotion analysis using support vector regression
Physical and mental diseases were deeply affected by stress and negative emotions. In
general, emotions can be roughly recognized by facial expressions. Since facial expressions …
general, emotions can be roughly recognized by facial expressions. Since facial expressions …
A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized to the medial Golgi cisternae
JY Zheng, T Koda, T Fujiwara, M Kishi… - Journal of Cell …, 1998 - journals.biologists.com
Small GTP-binding proteins of the Rab family play important roles at defined steps of vesicular
transport in protein secretion and the endocytosis pathway. In mammals, more than 30 …
transport in protein secretion and the endocytosis pathway. In mammals, more than 30 …
Oncogenic variant RON160 expression in breast cancer and its potential as a therapeutic target by small molecule tyrosine kinase inhibitor
HP Yao, CM Zhuang, YQ Zhou, JY Zeng… - Current Cancer Drug …, 2013 - ingentaconnect.com
Aberrant expression of the RON receptor tyrosine kinase contributes to breast cancer
malignancy. Although clinical trials of RON targeting are underway, the intriguing issue is the …
malignancy. Although clinical trials of RON targeting are underway, the intriguing issue is the …
Regression of prostate cancer xenografts by a lentiviral vector specifically expressing diphtheria toxin A
J Zheng, D Chen, J Chan, D Yu, E Ko, S Pang - Cancer gene therapy, 2003 - nature.com
We have constructed a prostate-specific lentiviral vector based on the promoter of the
prostate-specific antigen (PSA). The PSA promoter-based lentiviral vector has been used to deliver …
prostate-specific antigen (PSA). The PSA promoter-based lentiviral vector has been used to deliver …
p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells
MS Veena, R Wilken, JY Zheng, A Gholkar… - Journal of Biological …, 2014 - jbc.org
The molecular mechanism of p16-mediated senescence in cisplatin-treated cancer cells is
not fully understood. Here we show that cisplatin treatment of head and neck cancer cells …
not fully understood. Here we show that cisplatin treatment of head and neck cancer cells …
Changing El Niño–Southern oscillation in a warming climate
…, B Ng, F Jia, Y Yang, J Ying, XT Zheng… - Nature Reviews Earth & …, 2021 - nature.com
Originating in the equatorial Pacific, the El Niño–Southern Oscillation (ENSO) has highly
consequential global impacts, motivating the need to understand its responses to …
consequential global impacts, motivating the need to understand its responses to …
Based on support vector regression for emotion recognition using physiological signals
Facial expression are widely used for emotion recognition. Facial expressions may be
expressed differently by different people subjectively, inaccurate results are unavoidable. …
expressed differently by different people subjectively, inaccurate results are unavoidable. …