Small-molecule inhibitor BMS-777607 induces breast cancer cell polyploidy with increased resistance to cytotoxic chemotherapy agents

S Sharma, JY Zeng, CM Zhuang, YQ Zhou… - Molecular cancer …, 2013 - aacrjournals.org
The RON receptor tyrosine kinase is a therapeutic target for cancer treatment. Here, we
report therapeutic effect and phenotypic change of breast cancer cells in response to BMS-…

Synergistic cementing efficiencies of nano-silica and micro-silica in carbonation resistance and sorptivity of concrete

LG Li, JY Zheng, PL Ng, AKH Kwan - Journal of Building Engineering, 2021 - Elsevier
Nano-silica (NS) and micro-silica (MS) are both effective in improving the strength and
durability of concrete, but their combined effect on a particular performance attribute may not be …

Synergistic activities of MET/RON inhibitor BMS-777607 and mTOR inhibitor AZD8055 to polyploid cells derived from pancreatic cancer and cancer stem cells

JY Zeng, S Sharma, YQ Zhou, HP Yao… - Molecular cancer …, 2014 - aacrjournals.org
Tyrosine kinase inhibitor BMS-777067 is an inhibitor of RON/MET receptor tyrosine kinases
currently under clinical trials. Here, we report the synergistic activity of BMS-777607 in …

Physiological emotion analysis using support vector regression

CY Chang, CW Chang, JY Zheng, PC Chung - Neurocomputing, 2013 - Elsevier
Physical and mental diseases were deeply affected by stress and negative emotions. In
general, emotions can be roughly recognized by facial expressions. Since facial expressions …

A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized to the medial Golgi cisternae

JY Zheng, T Koda, T Fujiwara, M Kishi… - Journal of Cell …, 1998 - journals.biologists.com
Small GTP-binding proteins of the Rab family play important roles at defined steps of vesicular
transport in protein secretion and the endocytosis pathway. In mammals, more than 30 …

Oncogenic variant RON160 expression in breast cancer and its potential as a therapeutic target by small molecule tyrosine kinase inhibitor

HP Yao, CM Zhuang, YQ Zhou, JY Zeng… - Current Cancer Drug …, 2013 - ingentaconnect.com
Aberrant expression of the RON receptor tyrosine kinase contributes to breast cancer
malignancy. Although clinical trials of RON targeting are underway, the intriguing issue is the …

Regression of prostate cancer xenografts by a lentiviral vector specifically expressing diphtheria toxin A

J Zheng, D Chen, J Chan, D Yu, E Ko, S Pang - Cancer gene therapy, 2003 - nature.com
We have constructed a prostate-specific lentiviral vector based on the promoter of the
prostate-specific antigen (PSA). The PSA promoter-based lentiviral vector has been used to deliver …

p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells

MS Veena, R Wilken, JY Zheng, A Gholkar… - Journal of Biological …, 2014 - jbc.org
The molecular mechanism of p16-mediated senescence in cisplatin-treated cancer cells is
not fully understood. Here we show that cisplatin treatment of head and neck cancer cells …

Changing El Niño–Southern oscillation in a warming climate

…, B Ng, F Jia, Y Yang, J Ying, XT Zheng… - Nature Reviews Earth & …, 2021 - nature.com
Originating in the equatorial Pacific, the El Niño–Southern Oscillation (ENSO) has highly
consequential global impacts, motivating the need to understand its responses to …

Based on support vector regression for emotion recognition using physiological signals

CY Chang, JY Zheng, CJ Wang - The 2010 international joint …, 2010 - ieeexplore.ieee.org
Facial expression are widely used for emotion recognition. Facial expressions may be
expressed differently by different people subjectively, inaccurate results are unavoidable. …