Rigosertib induces mitotic arrest and apoptosis in RAS-mutated rhabdomyosarcoma and neuroblastoma
JT Kowalczyk, X Wan, ER Hernandez, R Luo… - Molecular cancer …, 2021 - AACR
Relapsed pediatric rhabdomyosarcomas (RMS) and neuroblastomas (NBs) have a poor
prognosis despite multimodality therapy. In addition, the current standard of care for these …
prognosis despite multimodality therapy. In addition, the current standard of care for these …
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma
…, JS Schneekloth Jr, R Chari, JT Kowalczyk… - Nature …, 2024 - nature.com
Fusion-positive rhabdomyosarcoma (FP-RMS) is an aggressive pediatric sarcoma driven
primarily by the PAX3-FOXO1 fusion oncogene, for which therapies targeting PAX3-FOXO1 …
primarily by the PAX3-FOXO1 fusion oncogene, for which therapies targeting PAX3-FOXO1 …
Dying of stress: chemotherapy, radiotherapy, and small-molecule inhibitors in immunogenic cell death and immunogenic modulation
Innovative strategies to re-establish the immune-mediated destruction of malignant cells is
paramount to the success of anti-cancer therapy. Accumulating evidence suggests that …
paramount to the success of anti-cancer therapy. Accumulating evidence suggests that …
[HTML][HTML] Exploiting the immunogenic potential of standard of care radiation or cisplatin therapy in preclinical models of HPV-associated malignancies
JT Kowalczyk, KP Fabian, MR Padget… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Original research: Exploiting the immunogenic potential of standard of care radiation or
cisplatin therapy in preclinical models of HPV-associated malignancies - PMC Back to Top Skip …
cisplatin therapy in preclinical models of HPV-associated malignancies - PMC Back to Top Skip …
Multi-spectral immunofluorescence evaluation of the myeloid, T cell, and natural killer cell tumor immune microenvironment in chordoma may guide …
DC Lopez, YL Robbins, JT Kowalczyk… - Frontiers in …, 2022 - frontiersin.org
Background Chordoma is a rare, invasive, and devastating bone malignancy of residual
notochord tissue that arises at the skull base, sacrum, or spine. In order to maximize …
notochord tissue that arises at the skull base, sacrum, or spine. In order to maximize …
Preclinical therapeutic efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR inhibition in Neuroblastoma
S Stauffer, JS Roth, ER Hernandez, JT Kowalczyk… - Cancers, 2024 - mdpi.com
Simple Summary The prognosis for patients with relapsed neuroblastoma is poor, and novel
treatment options for these patients are needed. Some relapsed neuroblastoma tumors …
treatment options for these patients are needed. Some relapsed neuroblastoma tumors …
Exploiting docetaxel-induced tumor cell necrosis with tumor targeted delivery of IL-12
…, PL Chariou, DH Hamilton, JT Kowalczyk… - Cancer Immunology …, 2023 - Springer
There is strong evidence that chemotherapy can induce tumor necrosis which can be exploited
for the targeted delivery of immuno-oncology agents into the tumor microenvironment (…
for the targeted delivery of immuno-oncology agents into the tumor microenvironment (…
Chordoma cancer stem cell subpopulation characterization may guide targeted immunotherapy approaches to reduce disease recurrence
…, KP Fabian, M Padget, Y Robbins, JT Kowalczyk… - Frontiers in …, 2024 - frontiersin.org
Cancer stem cells (CSCs), a group of tumor-initiating and tumor-maintaining cells, may be
major players in the treatment resistance and recurrence distinctive of chordoma. …
major players in the treatment resistance and recurrence distinctive of chordoma. …
[BOOK][B] The influence of typology and texts of the Old Testament on the redaction of Matthew's gospel
A Kowalczyk - 2008 - digital.fides.org.pl
… The similarities between Moses and Jesus as well as between Joshua and Jesus do not …
He clearly takes pattern of the Book of Joshua too. In the third chapter I prove how precise …
He clearly takes pattern of the Book of Joshua too. In the third chapter I prove how precise …
Stepwise approach for nerve sparing without countertraction during robot-assisted radical prostatectomy: technique and outcomes
KJ Kowalczyk, AC Huang, ND Hevelone, SR Lipsitz… - European urology, 2011 - Elsevier
… /affiliation, grants or funding, consultancies, honoraria, stock ownership or options, expert
testimony, royalties, or patents filed, received, or pending), are the following: Dr Kowalczyk …
testimony, royalties, or patents filed, received, or pending), are the following: Dr Kowalczyk …