User profiles for Jiyang Yu

Jiyang Yu, PhD

- Verified email at stjude.org - Cited by 4537

Jiyang Yu

- Verified email at google.com - Cited by 426

Learning video stabilization using optical flow

J Yu, R Ramamoorthi - … of the IEEE/CVF conference on …, 2020 - openaccess.thecvf.com
We propose a novel neural network that infers the per-pixel warp fields for video stabilization
from the optical flow fields of the input video. While previous learning based video …

CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer's disease pathology

…, P Vogel, X Liu, GE Serrano, TG Beach, J Yu… - Nature …, 2023 - nature.com
Neurodegenerative diseases, including Alzheimer’s disease (AD), are characterized by
innate immune-mediated inflammation, but functional and mechanistic effects of the adaptive …

[HTML][HTML] G3BP1 is a tunable switch that triggers phase separation to assemble stress granules

…, U Yurtsever, Z Yang, J Wu, Y Li, Q Pan, J Yu… - Cell, 2020 - cell.com
The mechanisms underlying ribonucleoprotein (RNP) granule assembly, including the basis
for establishing and maintaining RNP granules with distinct composition, are unknown. One …

Adaptive spot-guided transformer for consistent local feature matching

J Yu, J Chang, J He, T Zhang… - Proceedings of the …, 2023 - openaccess.thecvf.com
Local feature matching aims at finding correspondences between a pair of images. Although
current detector-free methods leverage Transformer architecture to obtain an impressive …

Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy

…, C Qian, B Xu, A Kc, J Saravia, H Huang, J Yu… - Nature, 2019 - nature.com
Adoptive cell therapy represents a new paradigm in cancer immunotherapy, but it can be
limited by the poor persistence and function of transferred T cells 1 . Here we use an in vivo …

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

E Piovan, J Yu, V Tosello, D Herranz… - Cancer cell, 2013 - cell.com
Glucocorticoid resistance is a major driver of therapeutic failure in T cell acute lymphoblastic
leukemia (T-ALL). Here, we identify the AKT1 kinase as a major negative regulator of the …

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells

…, TLM Nguyen, Y Dhungana, G Neale, J Peng, J Yu… - Nature, 2018 - nature.com
Dendritic cells orchestrate the crosstalk between innate and adaptive immunity. CD8α +
dendritic cells present antigens to CD8 + T cells and elicit cytotoxic T cell responses to viruses, …

Network-based assessment of HDAC6 activity predicts preclinical and clinical responses to the HDAC6 inhibitor ricolinostat in breast cancer

…, S Jones, A High, J Peng, A Califano, K Kalinsky, J Yu… - Nature cancer, 2023 - nature.com
Inhibiting individual histone deacetylase (HDAC) is emerging as well-tolerated anticancer
strategy compared with pan-HDAC inhibitors. Through preclinical studies, we demonstrated …

Cross-cohort analysis identifies a TEAD4–MYCN positive feedback loop as the core regulatory element of high-risk neuroblastoma

…, G Lopez, C Capdevila, B Salvatori, J Yu… - Cancer …, 2018 - aacrjournals.org
High-risk neuroblastomas show a paucity of recurrent somatic mutations at diagnosis. As a
result, the molecular basis for this aggressive phenotype remains elusive. Recent progress in …

[HTML][HTML] Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia

…, M Konopleva, CH Pui, E Paietta, W Evans, J Yu… - Cancer cell, 2024 - cell.com
Leukemia can arise at various stages of the hematopoietic differentiation hierarchy, but the
impact of developmental arrest on drug sensitivity is unclear. Applying network-based …