Discovery of BI 224436, a noncatalytic site integrase inhibitor (NCINI) of HIV-1
…, M Amad, P Edwards, M Garneau, J Duan… - ACS medicinal …, 2014 - ACS Publications
An assay recapitulating the 3′ processing activity of HIV-1 integrase (IN) was used to
screen the Boehringer Ingelheim compound collection. Hit-to-lead and lead optimization …
screen the Boehringer Ingelheim compound collection. Hit-to-lead and lead optimization …
Preclinical profile of BI 224436, a novel HIV-1 non-catalytic-site integrase inhibitor
…, M Cordingley, R Coulombe, J Duan… - Antimicrobial agents …, 2014 - Am Soc Microbiol
BI 224436 is an HIV-1 integrase inhibitor with effective antiviral activity that acts through a
mechanism that is distinct from that of integrase strand transfer inhibitors (INSTIs). This 3-…
mechanism that is distinct from that of integrase strand transfer inhibitors (INSTIs). This 3-…
Preclinical characterization of BI 201335, a C-terminal carboxylic acid inhibitor of the hepatitis C virus NS3-NS4A protease
…, G Bolger, MG Cordingley, J Duan… - Antimicrobial agents …, 2010 - Am Soc Microbiol
BI 201335 is a hepatitis C virus (HCV) NS3-NS4A (NS3 coexpressed with NS4A) protease
inhibitor that has been shown to have potent clinical antiviral activity. It is a highly optimized …
inhibitor that has been shown to have potent clinical antiviral activity. It is a highly optimized …
Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb
W Kuang, J Tan, Y Duan, J Duan, W Wang, F Jin… - Biochemical and …, 2009 - Elsevier
Proliferation and differentiation of muscle stem cells must be tightly regulated by intrinsic and
extrinsic signals for effective regeneration and adaptive response. MicroRNAs have been …
extrinsic signals for effective regeneration and adaptive response. MicroRNAs have been …
Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux and interactions
Purpose Membrane transporters mediate many biological effects of chemicals and play a
major role in pharmacokinetics and drug resistance. The selection of viable drug candidates …
major role in pharmacokinetics and drug resistance. The selection of viable drug candidates …
The survival rates and risk factors of implants in the early stage: a retrospective study
Y Yang, H Hu, M Zeng, H Chu, Z Gan, J Duan, M Rong - BMC Oral Health, 2021 - Springer
Background Few large-sample studies in China have focused on the early survival of dental
implants. The present study aimed to report the early survival rates of implants and …
implants. The present study aimed to report the early survival rates of implants and …
[HTML][HTML] Long noncoding RNA SChLAP1 accelerates the proliferation and metastasis of prostate cancer via targeting miR-198 and promoting the MAPK1 pathway
Y Li, H Luo, N Xiao, J Duan, Z Wang, S Wang - Oncology research, 2018 - ncbi.nlm.nih.gov
Prostate cancer has become the most commonly diagnosed and the second leading cause
of cancer-related deaths in males. The long noncoding RNA second chromosome locus …
of cancer-related deaths in males. The long noncoding RNA second chromosome locus …
Evaluation of antiurolithic effect and the possible mechanisms of Desmodium styracifolium and Pyrrosiae petiolosa in rats
J Mi, J Duan, J Zhang, J Lu, H Wang, Z Wang - Urological research, 2012 - Springer
Chinese herbs Desmodium styracifolium (Ds) and Pyrrosiae petiolosa (Pp) have been widely
used to treat urolithiasis with few side effects in traditional Chinese medicine (TCM). In vitro …
used to treat urolithiasis with few side effects in traditional Chinese medicine (TCM). In vitro …
Discovery of the first thumb pocket 1 NS5B polymerase inhibitor (BILB 1941) with demonstrated antiviral activity in patients chronically infected with genotype 1 …
…, MA Poupart, YS Tsantrizos, J Duan… - Journal of Medicinal …, 2012 - ACS Publications
Combinations of direct acting antivirals (DAAs) that have the potential to suppress
emergence of resistant virus and that can be used in interferon-sparing regimens represent a …
emergence of resistant virus and that can be used in interferon-sparing regimens represent a …
A strong tracking square root central difference FastSLAM for unmanned intelligent vehicle with adaptive partial systematic resampling
D Liu, J Duan, H Shi - IEEE Transactions on Intelligent …, 2016 - ieeexplore.ieee.org
An improved fast simultaneous localization and mapping (FastSLAM) algorithm based on
the strong tracking square root central difference Kalman filter (STSRCDKF) with adaptive …
the strong tracking square root central difference Kalman filter (STSRCDKF) with adaptive …