Comprehensive and integrative genomic characterization of hepatocellular carcinoma
Liver cancer has the second highest worldwide cancer mortality rate and has limited
therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole-exome …
therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole-exome …
Potential Sites of Bioactive Gibberellin Production during Reproductive Growth in Arabidopsis
J Hu, MG Mitchum, N Barnaby, BT Ayele… - The Plant …, 2008 - academic.oup.com
Gibberellin 3-oxidase (GA3ox) catalyzes the final step in the synthesis of bioactive gibberellins
(GAs). We examined the expression patterns of all four GA3ox genes in Arabidopsis …
(GAs). We examined the expression patterns of all four GA3ox genes in Arabidopsis …
The Arabidopsis F-box protein SLEEPY1 targets gibberellin signaling repressors for gibberellin-induced degradation
The nuclear DELLA proteins are highly conserved repressors of hormone gibberellin (GA)
signaling in plants. In Arabidopsis thaliana, GA derepresses its signaling pathway by inducing …
signaling in plants. In Arabidopsis thaliana, GA derepresses its signaling pathway by inducing …
DELLA proteins and gibberellin-regulated seed germination and floral development in Arabidopsis
L Tyler, SG Thomas, J Hu, A Dill, JM Alonso… - Plant …, 2004 - academic.oup.com
RGA (repressor of ga1-3) and GAI (gibberellin insensitive) are negative regulators of plant
hormone gibberellin (GA) signaling in Arabidopsis. The GA-deficient mutant ga1-3 is a …
hormone gibberellin (GA) signaling in Arabidopsis. The GA-deficient mutant ga1-3 is a …
[HTML][HTML] Comprehensive pan-genomic characterization of adrenocortical carcinoma
…, J Drummond, R Gibbs, W Hale, Y Han, A Hawes, J Hu… - Cancer cell, 2016 - cell.com
We describe a comprehensive genomic characterization of adrenocortical carcinoma (ACC).
Using this dataset, we expand the catalogue of known ACC driver genes to include …
Using this dataset, we expand the catalogue of known ACC driver genes to include …
Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus
MA Samols, J Hu, RL Skalsky, R Renne - Journal of virology, 2005 - Am Soc Microbiol
MicroRNAs (miRNAs) are small, noncoding regulatory RNA molecules that bind to 3′
untranslated regions (UTRs) of mRNAs to either prevent their translation or induce their …
untranslated regions (UTRs) of mRNAs to either prevent their translation or induce their …
PIL5, a Phytochrome-Interacting bHLH Protein, Regulates Gibberellin Responsiveness by Binding Directly to the GAI and RGA Promoters in Arabidopsis Seeds
E Oh, S Yamaguchi, J Hu, J Yusuke, B Jung… - The Plant …, 2007 - academic.oup.com
Previous work showed that PHYTOCHROME-INTERACTING FACTOR3-LIKE5 (PIL5), a light-labile
basic helix-loop-helix protein, inhibits seed germination by repressing GIBBERELLIN …
basic helix-loop-helix protein, inhibits seed germination by repressing GIBBERELLIN …
Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis
…, DM Muzny, H Doddapaneni, J Hu… - Blood, The Journal …, 2014 - ashpublications.org
Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by
lesions composed of pathological CD207 + dendritic cells with an inflammatory infiltrate. …
lesions composed of pathological CD207 + dendritic cells with an inflammatory infiltrate. …
Use of exome sequencing for infants in intensive care units: ascertainment of severe single-gene disorders and effect on medical management
…, MF Wangler, D Scott, C Brown, J Hu… - JAMA …, 2017 - jamanetwork.com
Importance While congenital malformations and genetic diseases are a leading cause of
early infant death, to our knowledge, the contribution of single-gene disorders in this group is …
early infant death, to our knowledge, the contribution of single-gene disorders in this group is …
Integrated molecular characterization of testicular germ cell tumors
…, JC Jayaseelan, V Korchina, L Lewis, J Hu… - Cell reports, 2018 - cell.com
We studied 137 primary testicular germ cell tumors (TGCTs) using high-dimensional assays
of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited …
of genomic, epigenomic, transcriptomic, and proteomic features. These tumors exhibited …