Simple Summary Immunotherapies have revolutionized the field of cancer therapeutics, yet
a substantial subset of patients fail to respond. Recent efforts have focused on identifying …

Tertiary lymphoid structures (TLS), also known as ectopic lymphoid structures (ELS) or
tertiary lymphoid organs (TLO), represent a unique subset of lymphoid tissues noted for their …

Tumor-infiltrating lymphocytes (TILs) contain substantial numbers of CD4 + T cells mediating
pro- and antitumor functions. While CD4 + Tregs are well characterized and known to …

Background Stimulator of Interferon Genes (STING) is a dsDNA sensor that triggers type I
inflammatory responses. Recent data from our group and others support the therapeutic …

Original research: Dendritic cell vaccines targeting tumor blood vessel antigens in
combination with dasatinib induce therapeutic immune responses in patients with checkpoint-…

… Jessica N Filderman … Jessica N Filderman and Walter J Storkus contributed equally to
this work. … Jessica N Filderman and Walter J Storkus contributed equally to this work. …

We previously reported that dendritic cell (DC)-based vaccines targeting antigens expressed
by tumor-associated vascular endothelial cells (VECs) and pericytes effectively control …

For students with persistent reading difficulties, research suggests one of the most effective
ways to intensify interventions is to individualize instruction through use of performance data…

… The Dissertation Committee for Marissa Jenette Filderman Certifies that this is the approved
… A majority of the interventions reported in the meta-analysis conducted by Filderman et al. (…

For students who show inadequate response to research-based intervention, intensification
of intervention using data-based decision making (DBDM) is recommended. There is a …