STING agonists as cancer therapeutics
A Amouzegar, M Chelvanambi, JN Filderman… - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapies have revolutionized the field of cancer therapeutics, yet
a substantial subset of patients fail to respond. Recent efforts have focused on identifying …
a substantial subset of patients fail to respond. Recent efforts have focused on identifying …
STINGing the tumor microenvironment to promote therapeutic tertiary lymphoid structure development
JN Filderman, M Appleman, M Chelvanambi… - Frontiers in …, 2021 - frontiersin.org
Tertiary lymphoid structures (TLS), also known as ectopic lymphoid structures (ELS) or
tertiary lymphoid organs (TLO), represent a unique subset of lymphoid tissues noted for their …
tertiary lymphoid organs (TLO), represent a unique subset of lymphoid tissues noted for their …
Finding the right help in the tumor microenvironment
JN Filderman, WJ Storkus - The Journal of Clinical …, 2022 - Am Soc Clin Investig
Tumor-infiltrating lymphocytes (TILs) contain substantial numbers of CD4 + T cells mediating
pro- and antitumor functions. While CD4 + Tregs are well characterized and known to …
pro- and antitumor functions. While CD4 + Tregs are well characterized and known to …
Antagonism of regulatory ISGs enhances the anti-melanoma efficacy of STING agonists
JN Filderman, JL Taylor, J Wang, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Background Stimulator of Interferon Genes (STING) is a dsDNA sensor that triggers type I
inflammatory responses. Recent data from our group and others support the therapeutic …
inflammatory responses. Recent data from our group and others support the therapeutic …
[HTML][HTML] Dendritic cell vaccines targeting tumor blood vessel antigens in combination with dasatinib induce therapeutic immune responses in patients with checkpoint …
…, M Chelvanambi, RJ Fecek, JN Filderman… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Original research: Dendritic cell vaccines targeting tumor blood vessel antigens in
combination with dasatinib induce therapeutic immune responses in patients with checkpoint-…
combination with dasatinib induce therapeutic immune responses in patients with checkpoint-…
Platelet STING agonism and venous thrombosis: translational implications for improved disease outcomes
JN Filderman, JJ Luke, WJ Storkus - 2023 - academic.oup.com
… Jessica N Filderman … Jessica N Filderman and Walter J Storkus contributed equally to
this work. … Jessica N Filderman and Walter J Storkus contributed equally to this work. …
this work. … Jessica N Filderman and Walter J Storkus contributed equally to this work. …
[HTML][HTML] Therapeutic Anti-Tumor Efficacy of DC-Based Vaccines Targeting TME-Associated Antigens Is Improved When Combined with a Chemokine-Modulating …
JL Taylor, KM Kokolus, PH Basse, JN Filderman… - Vaccines, 2024 - mdpi.com
We previously reported that dendritic cell (DC)-based vaccines targeting antigens expressed
by tumor-associated vascular endothelial cells (VECs) and pericytes effectively control …
by tumor-associated vascular endothelial cells (VECs) and pericytes effectively control …
Data-based decision making in reading interventions: A synthesis and meta-analysis of the effects for struggling readers
For students with persistent reading difficulties, research suggests one of the most effective
ways to intensify interventions is to individualize instruction through use of performance data…
ways to intensify interventions is to individualize instruction through use of performance data…
Using student data to improve response to a multisyllabic word reading intervention: the effects of varying levels of data use
MJ Filderman - 2020 - repositories.lib.utexas.edu
… The Dissertation Committee for Marissa Jenette Filderman Certifies that this is the approved
… A majority of the interventions reported in the meta-analysis conducted by Filderman et al. (…
… A majority of the interventions reported in the meta-analysis conducted by Filderman et al. (…
Effects of varying levels of data use to intensify a multisyllabic word reading intervention for upper elementary students with or at risk for reading disabilities
MJ Filderman, JR Toste - Journal of Learning Disabilities, 2022 - journals.sagepub.com
For students who show inadequate response to research-based intervention, intensification
of intervention using data-based decision making (DBDM) is recommended. There is a …
of intervention using data-based decision making (DBDM) is recommended. There is a …