Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus
…, JH Livingston, SA Lynch, RF Massey, JF Meritet… - Nature …, 2006 - nature.com
Aicardi-Goutières syndrome (AGS) presents as a severe neurological brain disease and is
a genetic mimic of the sequelae of transplacentally acquired viral infection 1 , 2 . Evidence …
a genetic mimic of the sequelae of transplacentally acquired viral infection 1 , 2 . Evidence …
Gene therapy in patients with transfusion-dependent β-thalassemia
…, C Poirot, C Brouzes, JF Meritet… - … England Journal of …, 2018 - Mass Medical Soc
Background Donor availability and transplantation-related risks limit the broad use of
allogeneic hematopoietic-cell transplantation in patients with transfusion-dependent β-thalassemia…
allogeneic hematopoietic-cell transplantation in patients with transfusion-dependent β-thalassemia…
[HTML][HTML] Gene therapy in a patient with sickle cell disease
<p id="p001">Sickle cell disease results from a homozygous missense mutation in the β-globin
gene that causes polymerization of hemoglobin S. Gene therapy for patients with this …
gene that causes polymerization of hemoglobin S. Gene therapy for patients with this …
Genetic diversity within human erythroviruses: identification of three genotypes
…, V Marinho, G De Saint Maur, JF Meritet… - Journal of …, 2002 - Am Soc Microbiol
B19 virus is a human virus belonging to the genus Erythrovirus. The genetic diversity
among B19 virus isolates has been reported to be very low, with less than 2% nucleotide …
among B19 virus isolates has been reported to be very low, with less than 2% nucleotide …
Janus kinase inhibition in the Aicardi–Goutières syndrome
…, A Collins, SR Keller, P Lebon, JF Meritet… - … England Journal of …, 2020 - Mass Medical Soc
JAK Inhibition in the Aicardi–Goutières Syndrome Patients with the Aicardi–Goutières
syndrome, an autosomal recessive disorder that affects the central nervous system, immune …
syndrome, an autosomal recessive disorder that affects the central nervous system, immune …
Production of infectious hepatitis C virus in primary cultures of human adult hepatocytes
P Podevin, A Carpentier, V Pène, L Aoudjehane… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Although hepatitis C virus (HCV) can be grown in the
hepatocarcinoma-derived cell line Huh-7, a cell-culture model is needed that supports its complete, …
hepatocarcinoma-derived cell line Huh-7, a cell-culture model is needed that supports its complete, …
[HTML][HTML] Clinical, virological and imaging profile in patients with prolonged forms of COVID-19: a cross-sectional study
…, D Batisse, G Spiridon, V Le Baut, JF Meritet… - The Journal of …, 2021 - ncbi.nlm.nih.gov
… Dominique Salmon-Ceron, a, b, 1, ⁎ Dorsaf Slama, a, 1 Thomas De Broucker, c Marina
Karmochkine, a Juliette Pavie, a Emmanuel Sorbets, d, b Nicolas Etienne, a, b Dominique …
Karmochkine, a Juliette Pavie, a Emmanuel Sorbets, d, b Nicolas Etienne, a, b Dominique …
TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice
…, R Kratzer, K Lelu-Santolaria, A Evlachev, JF Meritet… - Gut, 2015 - gut.bmj.com
Objective To assess a new adenovirus-based immunotherapy as a novel treatment approach
to chronic hepatitis B (CHB). Methods TG1050 is a non-replicative adenovirus serotype 5 …
to chronic hepatitis B (CHB). Methods TG1050 is a non-replicative adenovirus serotype 5 …
PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator–dependent autoimmunity
AL Mathieu, E Verronese, GI Rice, F Fouyssac… - Journal of Allergy and …, 2015 - Elsevier
Background PRKDC encodes for DNA-dependent protein kinase catalytic subunit (DNA-PKcs),
a kinase that forms part of a complex (DNA-dependent protein kinase [DNA-PK]) crucial …
a kinase that forms part of a complex (DNA-dependent protein kinase [DNA-PK]) crucial …
Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus
…, R Firth, E Harrison, AR Rosenberg, JF Meritet… - Gut, 2018 - gut.bmj.com
Objective Recently approved direct acting antivirals provide transformative therapies for
chronic hepatitis C virus (HCV) infection. The major clinical challenge remains to identify the …
chronic hepatitis C virus (HCV) infection. The major clinical challenge remains to identify the …