Due to the low performance of traditional virtual reality roaming systems, three-dimensional vision technology is used to optimize the design of interactive virtual reality indoor space roaming systems from the three aspects of hardware, software, and database. The optimization of the hardware system is mainly aimed at the connection structure of the rover and the interactive module. Collect all relevant data of indoor space and system operation, and store them in a certain format to get the design results of the system database. With the support of hardware equipment and database, the function of interactive virtual reality indoor space roaming is realized through the steps of creating virtual scene of indoor space, determining the roaming mode of 3D virtual reality and the path planning of indoor space roaming. Through the system test experiment, it is concluded that compared with the traditional roaming system, the designed interactive virtual reality indoor space roaming system has a higher success rate and better interactivity.