[CITATION][C] Influenza infection exerts prominent inflammatory and thrombotic effects on atherosclerotic plaques of apo E-deficient mice
S Litovsky, P Wyde, M Madjid, A Akhtar… - Journal of the American …, 2002 - jacc.org
Influenza infection exerts prominent inflammatory and thrombotic effects on atherosclerotic
plaques of apo E- deficient mice | Journal of the American College of Cardiology …
plaques of apo E- deficient mice | Journal of the American College of Cardiology …
Influenza infection exerts prominent inflammatory and thrombotic effects on the atherosclerotic plaques of apolipoprotein E–deficient mice
Background—The role of infection in the development and complications of atherosclerosis
has been the focus of much attention. We reported previously that influenza vaccination was
associated with reduced risk of recurrent myocardial infarction. Here, we report the effect of
influenza A virus on the apolipoprotein E–deficient (apoE−/−) mouse, an animal model of
atherosclerosis. Methods and Results—Twenty-four apoE−/− mice> 24 months old were
injected with 1 LD50 (lethal dose 50) of influenza A virus. Ten wild-type C57BL/6 infected …
has been the focus of much attention. We reported previously that influenza vaccination was
associated with reduced risk of recurrent myocardial infarction. Here, we report the effect of
influenza A virus on the apolipoprotein E–deficient (apoE−/−) mouse, an animal model of
atherosclerosis. Methods and Results—Twenty-four apoE−/− mice> 24 months old were
injected with 1 LD50 (lethal dose 50) of influenza A virus. Ten wild-type C57BL/6 infected …
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