Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease
Activation of microglia by classical inflammatory mediators can convert astrocytes into a
neurotoxic A1 phenotype in a variety of neurological diseases 1 , 2 . Development of agents that …
neurotoxic A1 phenotype in a variety of neurological diseases 1 , 2 . Development of agents that …
Injectable chitosan hyaluronic acid hydrogels for cartilage tissue engineering
Injectable cartilaginous constructs that can form gels in tissue defects have many advantages
in tissue engineering applications. In this study we created an injectable hydrogel …
in tissue engineering applications. In this study we created an injectable hydrogel …
Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
INTRODUCTION Parkinson’s disease (PD) is the second most common neurodegenerative
disorder and leads to slowness of movement, tremor, rigidity, and, in the later stages of PD, …
disorder and leads to slowness of movement, tremor, rigidity, and, in the later stages of PD, …
Poly (ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease
INTRODUCTION Parkinson’s disease (PD) is the second most common neurodegenerative
disorder. Intracellular protein aggregates composed primarily of α-synuclein lead to …
disorder. Intracellular protein aggregates composed primarily of α-synuclein lead to …
A nuclease that mediates cell death induced by DNA damage and poly (ADP-ribose) polymerase-1
Y Wang, R An, GK Umanah, H Park, K Nambiar… - Science, 2016 - science.org
INTRODUCTION Poly(ADP-ribose) (PAR) polymerase-1 (PARP-1) is a nuclear enzyme
responding to oxidative stress and DNA damage. Excessive activation of PARP-1 causes an …
responding to oxidative stress and DNA damage. Excessive activation of PARP-1 causes an …
Roll-to-roll gravure printed electrochemical sensors for wearable and medical devices
As recent developments in noninvasive biosensors spearhead the thrust toward personalized
health and fitness monitoring, there is a need for high throughput, cost-effective fabrication …
health and fitness monitoring, there is a need for high throughput, cost-effective fabrication …
Cancer drug response profile scan (CDRscan): a deep learning model that predicts drug effectiveness from cancer genomic signature
Y Chang, H Park, HJ Yang, S Lee, KY Lee, TS Kim… - Scientific reports, 2018 - nature.com
In the era of precision medicine, cancer therapy can be tailored to an individual patient
based on the genomic profile of a tumour. Despite the ever-increasing abundance of cancer …
based on the genomic profile of a tumour. Despite the ever-increasing abundance of cancer …
[PDF][PDF] A scientometric study of digital literacy, ICT literacy, information literacy, and media literacy.
Purpose: Digital literacy and related fields have received interests from scholars and
practitioners for more than 20 years; nonetheless, academic communities need to systematically …
practitioners for more than 20 years; nonetheless, academic communities need to systematically …
Thermo-sensitive injectable hydrogel based on the physical mixing of hyaluronic acid and Pluronic F-127 for sustained NSAID delivery
The aim of this research is the development of a new type of intra-articularly injectable
thermo-sensitive hydrogels for the long-term delivery of Piroxicam (PX). The thermo-sensitive …
thermo-sensitive hydrogels for the long-term delivery of Piroxicam (PX). The thermo-sensitive …
Methylxanthine drug monitoring with wearable sweat sensors
Drug monitoring plays crucial roles in doping control and precision medicine. It helps physicians
tailor drug dosage for optimal benefits, track patients' compliance to prescriptions, and …
tailor drug dosage for optimal benefits, track patients' compliance to prescriptions, and …