User profiles for Hao Ge

Hao Ge

- Verified email at pku.edu.cn - Cited by 3683

Hao Ge

- Verified email at smail.nju.edu.cn - Cited by 2095

Hao Ge (葛昊)

- Verified email at mail.tsinghua.edu.cn - Cited by 955

A drug-likeness toolbox facilitates ADMET study in drug discovery

CY Jia, JY Li, GF Hao, GF Yang - Drug discovery today, 2020 - Elsevier
Highlights • Online resources facilitate in silico drug-likeness study. • Databases gathering
high quality and up to date data are essential for drug-likeness evaluation. • Web servers for …

Stochastic theory of nonequilibrium steady states. Part II: Applications in chemical biophysics

H Ge, M Qian, H Qian - Physics Reports, 2012 - Elsevier
The mathematical theory of nonequilibrium steady state (NESS) has a natural application in
open biochemical systems which have sustained source(s) and sink(s) in terms of a …

Chemical manipulation of abscisic acid signaling: a new approach to abiotic and biotic stress management in agriculture

KAH Hewage, JF Yang, D Wang, GF Hao… - Advanced …, 2020 - Wiley Online Library
The phytohormone abscisic acid (ABA) is the best‐known stress signaling molecule in
plants. ABA protects sessile land plants from biotic and abiotic stresses. The conserved …

Acoustic topological insulator and robust one-way sound transport

C He, X Ni, H Ge, XC Sun, YB Chen, MH Lu, XP Liu… - Nature physics, 2016 - nature.com
Topological design of materials enables topological symmetries and facilitates unique
backscattering-immune wave transport 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , …

[HTML][HTML] Mechanism of transcriptional bursting in bacteria

S Chong, C Chen, H Ge, XS Xie - Cell, 2014 - cell.com
Transcription of highly expressed genes has been shown to occur in stochastic bursts. But
the origin of such ubiquitous phenomenon has not been understood. Here, we present the …

Enhanced efflux activity facilitates drug tolerance in dormant bacterial cells

…, Q Ma, Y Zhao, Y Ke, Y Zhu, H Chen, MAB Baker, H Ge… - Molecular cell, 2016 - cell.com
Natural variations in gene expression provide a mechanism for multiple phenotypes to arise
in an isogenic bacterial population. In particular, a sub-group termed persisters show high …

Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta

…, X Lu, YL Dang, H Wang, HY Lin, C Zhu, H Ge… - Cell research, 2018 - nature.com
The placenta is crucial for a successful pregnancy and the health of both the fetus and the
pregnant woman. However, how the human trophoblast lineage is regulated, including the …

The enhanced photoreduction of Cr (VI) to Cr (III) using carbon dots coupled TiO2 mesocrystals

Y Zhang, M Xu, H Li, H Ge, Z Bian - Applied Catalysis B: Environmental, 2018 - Elsevier
The photocatalytic reduction efficiency of hexavalent chromium (Cr 2 O 7 2− (Cr(VI)) is
suffering from high recombination of photoinduced charges, poor adsorption capacity of Cr(VI), …

Probing allostery through DNA

S Kim, E Broströmer, D Xing, J Jin, S Chong, H Ge… - Science, 2013 - science.org
Allostery is well documented for proteins but less recognized for DNA-protein interactions.
Here, we report that specific binding of a protein on DNA is substantially stabilized or …

Physical origins of entropy production, free energy dissipation, and their mathematical representations

H Ge, H Qian - Physical Review E—Statistical, Nonlinear, and Soft …, 2010 - APS
A unifying mathematical theory of nonequilibrium thermodynamics of stochastic systems in
terms of master equations is presented. As generalizations of isothermal entropy and free …