User profiles for Gourav Rakshit
 | Gourav RakshitBirla Institute of Technology, Mesra, Ranchi Verified email at bitmesra.ac.in Cited by 164 |
Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies
Cyclooxygenase (COX) and Lipoxygenase (LOX) are essential enzymes for arachidonic acid
(AA) to eicosanoids conversion. These AA-derived eicosanoids are essential for initiating …
(AA) to eicosanoids conversion. These AA-derived eicosanoids are essential for initiating …
In silico drug repurposing studies for the discovery of novel Salicyl-AMP ligase (MbtA) Inhibitors
Tuberculosis (TB) continues to pose a global health challenge, exacerbated by the rise of
drug-resistant strains. The development of new TB therapies is an arduous and time-…
drug-resistant strains. The development of new TB therapies is an arduous and time-…
Computational Simulations Reveal the Synergistic Action of Phytochemicals of Morus alba to Exert Anti-Alzheimer Activity via Inhibition of Acetylcholinesterase and …
Morus alba Linn. is a popular medium-sized tree with a potent neuroprotective activity such
as anti-Alzheimer. To date, it is not known which phytocompound of M. alba exerts anti-…
as anti-Alzheimer. To date, it is not known which phytocompound of M. alba exerts anti-…
Approaches for targeting the mycobactin biosynthesis pathway for novel anti-tubercular drug discovery: Where we stand
Introduction Several decades of antitubercular drug discovery efforts have focused on novel
antitubercular chemotherapies. However, recent efforts have greatly shifted toward …
antitubercular chemotherapies. However, recent efforts have greatly shifted toward …
Flavonoids as potential therapeutics against novel coronavirus disease-2019 (nCOVID-19)
Since time immemorial natural products have been a great source of medicine to mankind.
The anti-viral activities from several ayurvedic herbal medicines (in the form of crude extract …
The anti-viral activities from several ayurvedic herbal medicines (in the form of crude extract …
Tuberculosis and HIV responses threatened by nCOVID-19: A situation prompting an in silico investigation of reported MbtA inhibitors for combined inhibition of …
G Rakshit, V Jayaprakash - Structural Chemistry, 2023 - Springer
The menace of infectious diseases has constantly been a reason of concern for humankind
since time immemorial. As evident by the name, infectious diseases can infect a huge …
since time immemorial. As evident by the name, infectious diseases can infect a huge …
Dietary Polyphenols: Review on Chemistry/Sources, Bioavailability/Metabolism, Antioxidant Effects, and Their Role in Disease Management
Polyphenols, as secondary metabolites ubiquitous in plant sources, have emerged as pivotal
bioactive compounds with far-reaching implications for human health. Plant polyphenols …
bioactive compounds with far-reaching implications for human health. Plant polyphenols …
Molecular docking and molecular dynamics in natural products-based drug discovery
Natural products are unique compounds produced by the natural environment, including
plants, animals, and microorganisms. Plant-based medications have been used to treat various …
plants, animals, and microorganisms. Plant-based medications have been used to treat various …
Design, synthesis, biological and computational screening of novel pyridine-based thiadiazole derivatives as prospective anti-inflammatory agents
N Podila, NK Penddinti, M Rudrapal, G Rakshit… - Heliyon, 2024 - cell.com
In this study, a novel series of pyridine-based thiadiazole derivatives (NTD1-NTD5) were
synthesized as prospective anti-inflammatory agents by combining substituted carboxylic acid …
synthesized as prospective anti-inflammatory agents by combining substituted carboxylic acid …
New Benzimidazole-Triazole Derivatives as Topoisomerase I Inhibitors: Design, Synthesis, Anticancer Screening, and Molecular Modeling Studies
In this study, we designed, synthesized, and evaluated a series of 1,2,4-triazole benzimidazoles
for their cytotoxic effects against the A549, C6, and NIH3T3 cell lines. Additionally, these …
for their cytotoxic effects against the A549, C6, and NIH3T3 cell lines. Additionally, these …