User profiles for Filipe Liu

Filipe Liu

Argonne National Laboratory
Verified email at anl.gov
Cited by 640

MEMOTE for standardized genome-scale metabolic model testing

…, DY Lee, SY Lee, S Lee, NE Lewis, F Liu… - Nature …, 2020 - nature.com
To the Editor—Reconstructing metabolic reaction networks enables the development of
testable hypotheses of an organism’s metabolism under different conditions 1. State-of-the-art …

The ModelSEED Biochemistry Database for the integration of metabolic annotations and the reconstruction, comparison and analysis of metabolic models for plants …

SMD Seaver, F Liu, Q Zhang, J Jeffryes… - Nucleic acids …, 2021 - academic.oup.com
For over 10 years, ModelSEED has been a primary resource for the construction of draft
genome-scale metabolic models based on annotated microbial or plant genomes. Now being …

ModelSEED v2: High-throughput genome-scale metabolic model reconstruction with enhanced energy biosynthesis pathway prediction

JP Faria, F Liu, JN Edirisinghe, N Gupta, SMD Seaver… - bioRxiv, 2023 - biorxiv.org
Since the release of ModelSEED in 2010, the systems biology research community has
used the ModelSEED genome-scale metabolic model reconstruction pipeline to build over …

Discovery and implementation of a novel pathway for n-butanol production via 2-oxoglutarate

S Ferreira, R Pereira, F Liu, P Vilaça, I Rocha - Biotechnology for biofuels, 2019 - Springer
Background One of the European Union directives indicates that 10% of all fuels must be bio-synthesized
by 2020. In this regard, biobutanol—natively produced by clostridial strains—…

Chemical-damage MINE: A database of curated and predicted spontaneous metabolic reactions

JG Jeffryes, C Lerma-Ortiz, F Liu, A Golubev… - Metabolic …, 2022 - Elsevier
Spontaneous reactions between metabolites are often neglected in favor of emphasizing
enzyme-catalyzed chemistry because spontaneous reaction rates are assumed to be …

A KBase case study on genome-wide transcriptomics and plant primary metabolism in response to drought stress in Sorghum.

…, P Dehal, T Gu, M Joachimiak, C Lerma-Ortiz, F Liu… - Current plant …, 2021 - Elsevier
A better understanding of the genetic and metabolic mechanisms that confer stress resistance
and tolerance in plants is key to engineering new crops through advanced breeding …

TranSyT, an innovative framework for identifying transport systems

E Cunha, D Lagoa, JP Faria, F Liu, CS Henry… - …, 2023 - academic.oup.com
Motivation The importance and rate of development of genome-scale metabolic models
have been growing for the last few years, increasing the demand for software solutions that …

TranSyT, an innovative framework for identifying transport systems

D Lagoa, JP Faria, F Liu, E Cunha, CS Henry, O Dias - biorxiv, 2021 - biorxiv.org
The importance and rate of development of genome-scale metabolic models have been
growing for the last years, increasing the demand for software solutions that automate several …

Development and application of efficient pathway enumeration algorithms for metabolic engineering applications

F Liu, P Vilaça, I Rocha, M Rocha - Computer methods and programs in …, 2015 - Elsevier
Metabolic Engineering (ME) aims to design microbial cell factories towards the production of
valuable compounds. In this endeavor, one important task relates to the search for the most …

Computational tools for pathway optimization towards metabolic engineering applications

FAW Liu - 2013 - search.proquest.com
Metabolic Engineering targets the microorganism's cellular metabolism to design new
strains with an industrial purpose. Applications of these metabolic manipulations in …