Hepatocellular carcinoma (HCC) is a highly malignant tumor with a poor prognosis. Treatment
of HCC is complicated by the fact that the disease is often diagnosed at an advanced …

Background: Severe acute respiratory syndrome (SARS) is an infectious disease which was
caused by a novel coronavirus (SARS-CoV). SARS has caused an outbreak in the world …

Simple Summary About 5–10% of breast cancers are related to heredity. Very often, affected
individuals will carry only a single mutation defect in any of the hereditary breast and …

Differences in the mutation spectrum across ethnicities suggest the importance of identifying
genes in addition to common high penetrant genes to estimate the associated breast cancer …

The germline carrier of the BRCA1 pathogenic mutation has been well proven to confer an
increased risk of breast and ovarian cancer. Despite BRCA1 biallelic pathogenic mutations …

Background Germline TP53 mutations are associated with Li-Fraumeni syndrome, a severe
and rare hereditary cancer syndrome. Despite the rarity of germline TP53 mutations, the …

Simple Summary Breast cancer is the most commonly diagnosed cancer in women globally.
BRCA1 and BRCA2 mutations are most prevalent in hereditary breast cancer and are …

Targeted therapeutic agents such as poly (ADP-ribose) polymerases (PARP) inhibitors have
emerged in treating cancers associated with germline BRCA mutations. Recently studies …

Simple Summary The NCCN Clinical Practice Guidelines are testing criteria used to identify
high-risk individuals associated with an increased risk of breast, ovarian, pancreatic, and …

This study evaluated the significance of circulating bone marrow‐derived endothelial
progenitor cells (EPCs) in patients with hepatocellular carcinoma (HCC), a solid tumor with rich …