Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together
with polygenetic risk stratification can contribute towards planning of feasible and efficient …

The genetic basis of Lewy body dementia (LBD) is not well understood. Here, we performed
whole-genome sequencing in large cohorts of LBD cases and neurologically healthy …

Background: MicroRNAs have been postulated as potential biomarkers for Alzheimer’s
disease (AD). Exosomes are nanovesicles which transport microRNAs, proteins, and other …

Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF)
reflect core features of the pathogenesis of Alzheimer’s disease (AD) more directly than …

The genetic variant rs72824905-G (minor allele) in the PLCG2 gene was previously
associated with a reduced Alzheimer’s disease risk (AD). The role of PLCG2 in immune system …

Objective The aim of this research is to identify the stage of Alzheimer’s Disease (AD) patients
through the use of mobility data and deep learning models. This process facilitates the …

Oculomotor behavior can provide insight into the integrity of widespread cortical networks,
which may contribute to the differential diagnosis between Alzheimer's disease and …

Background The arrival of new disease-modifying treatments for Alzheimer’s disease (AD)
requires the identification of subjects at risk in a simple, inexpensive, and non-invasive way. …

Multiple system atrophy (MSA) is an adult-onset, sporadic synucleinopathy characterized by
parkinsonism, cerebellar ataxia, and dysautonomia. The genetic architecture of MSA is …

Introduction The objective of this study was to investigate and compare optic nerve and retinal
layers in eyes of patients with mild cognitive impairment (MCI) and Alzheimer's disease (…