Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort …

…, D Vallisa, M Martelli, E Derenzini, A Guarini… - The Lancet …, 2020 - thelancet.com
Background Several small studies on patients with COVID-19 and haematological
malignancies are available showing a high mortality in this population. The Italian Hematology …

High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial

…, AA Brandes, J Fajardo, H Gomez, A Guarini… - The Lancet, 2009 - thelancet.com
Background Chemotherapy with high-dose methotrexate is the conventional approach to
treat primary CNS lymphomas, but superiority of polychemotherapy compared with high-dose …

[HTML][HTML] Pharmacologic or genetic targeting of glutamine synthetase skews macrophages toward an M1-like phenotype and inhibits tumor metastasis

…, WH Lamers, B Ghesquière, DW McVicar, A Guarini… - Cell reports, 2017 - cell.com
Glutamine-synthetase (GS), the glutamine-synthesizing enzyme from glutamate, controls
important events, including the release of inflammatory mediators, mammalian target of …

Psychological distress in outpatients with lymphoma during the COVID-19 pandemic

…, G Opinto, E Silvestris, C Cormio, A Guarini… - Frontiers in …, 2020 - frontiersin.org
Cancer patients are a population at high risk of contracting COVID-19 and, also of
developing severe complications due to the infection, which is especially true when they are …

[HTML][HTML] An intelligent non-invasive system for automated diagnosis of anemia exploiting a novel dataset

…, MG Camporeale, F Clemente, A Guarini… - Artificial Intelligence in …, 2023 - Elsevier
Anemia is a condition in which the oxygen-carrying capacity of red blood cells is insufficient
to meet the body's physiological needs. It affects billions of people worldwide. An early …

Ovarian function after cancer treatment in young women affected by Hodgkin disease (HD)

L Giuseppe, G Attilio, DN Edoardo, G Loredana… - …, 2007 - Taylor & Francis
We have evaluated the best method to assess the ovarian reserve and the ovarian protective
effect of GnRH-analog (GnRH-a), in 29 women with Hodgkin's disease (HD) treated with …

Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma

…, M Mattioli, D Ronchetti, F Morabito, A Guarini… - Clinical Cancer …, 2009 - AACR
Purpose: To determine a “gene/molecular fingerprint” of multiple myeloma endothelial cells
and identify vascular mechanisms governing the malignant progression from quiescent …

[HTML][HTML] Multiple myeloma treatment in real-world clinical practice: results of a prospective, multinational, noninterventional study

…, C Califano, F Di Raimondo, A Guarini… - … Myeloma and Leukemia, 2018 - Elsevier
Background The present prospective, multinational, noninterventional study aimed to
document and describe real-world treatment regimens and disease progression in multiple …

[HTML][HTML] Anaemia detection based on sclera and blood vessel colour estimation

…, MG Camporeale, A Dipalma, A Guarini… - … Signal Processing and …, 2023 - Elsevier
Anaemia is a global public health problem with major consequences for human health.
Noninvasive methods must be investigated to determine a sick person's anaemic status or …

Hepatocellular carcinoma treatment over sorafenib: epigenetics, microRNAs and microenvironment. Is there a light at the end of the tunnel?

…, G Angarano, O Brunetti, A Guarini… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Sorafenib is currently the only approved therapy in hepatocellular carcinoma (HCC).
Alternative first- and second-line treatments are a significant unmet medical need, and …