User profiles for Andrea Gambotto
![]() | Andrea GambottoUniversity of Pittsburgh Verified email at upmc.edu Cited by 10138 |
Human infection with highly pathogenic H5N1 influenza virus
A Gambotto, SM Barratt-Boyes, MD de Jong… - The Lancet, 2008 - thelancet.com
Highly pathogenic H5N1 influenza A viruses have spread relentlessly across the globe since
2003, and they are associated with widespread death in poultry, substantial economic loss …
2003, and they are associated with widespread death in poultry, substantial economic loss …
Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
…, BL Haagmans, E Korkmaz, LD Falo, A Gambotto - …, 2020 - thelancet.com
Background Coronaviruses pose a serious threat to global health as evidenced by Severe
Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and COVID…
Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and COVID…
Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis
…, J Nash, Z Mi, SC Watkins, A Gambotto… - The Journal of …, 2005 - journals.aai.org
We have demonstrated previously that local, adenoviral-mediated gene transfer of viral IL-10
to a single joint of rabbits and mice with experimental arthritis can suppress disease in both …
to a single joint of rabbits and mice with experimental arthritis can suppress disease in both …
Dendritic cells acquire antigens from live cells for cross-presentation to CTL
Dendritic cells (DC) can readily capture Ag from dead and dying cells for presentation to
MHC class I-restricted CTL. We now show by using a primate model that DC also acquire Ag …
MHC class I-restricted CTL. We now show by using a primate model that DC also acquire Ag …
Effects of a SARS-associated coronavirus vaccine in monkeys
…, PD Robbins, WJ Bellini, S Barratt-Boyes, A Gambotto - The Lancet, 2003 - thelancet.com
The causative agent of severe acute respiratory syndrome (SARS) has been identified as a
new type of coronavirus. Here, we have investigated the ability of adenoviral delivery of …
new type of coronavirus. Here, we have investigated the ability of adenoviral delivery of …
Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the adult populations of The Gambia, South Africa, and the United States
…, D Rowe, PD Robbins, A Gambotto - Clinical and Vaccine …, 2004 - Am Soc Microbiol
One of the major limitations of the use of adenoviruses as gene therapy vectors is the
existence of preformed immunity in various populations. Recent studies have linked failure of …
existence of preformed immunity in various populations. Recent studies have linked failure of …
Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization
…, JM Katz, SM Barratt-Boyes, A Gambotto - Journal of …, 2006 - Am Soc Microbiol
The recent emergence of highly pathogenic avian influenza virus (HPAI) strains in poultry
and their subsequent transmission to humans in Southeast Asia have raised concerns about …
and their subsequent transmission to humans in Southeast Asia have raised concerns about …
Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-γ production
…, GF Scott, JC Lee, FJ Lynch, W Gao, A Gambotto… - Cytokine, 2002 - Elsevier
We have recently reported the identification of four novel members of the interleukin-1 (IL-1)
family which we designated as IL-1 homologue 1–4 (IL-1H1–4). These proteins exhibit …
family which we designated as IL-1 homologue 1–4 (IL-1H1–4). These proteins exhibit …
Role of toll-like receptors in changes in gene expression and NF-κB activation in mouse hepatocytes stimulated with lipopolysaccharide
…, X Gong, RA Shapiro, AA Gambotto… - Infection and …, 2002 - Am Soc Microbiol
The liver is an important site of host-microbe interaction. Although hepatocytes have been
reported to be responsive to lipopolysaccharide (LPS), the global gene expression changes …
reported to be responsive to lipopolysaccharide (LPS), the global gene expression changes …
Cisplatin-induced immune modulation in ovarian cancer mouse models with distinct inflammation profiles
The backbone of ovarian cancer treatment is platinum-based chemotherapy and aggressive
surgical debulking. New therapeutic approaches using immunotherapy via immune …
surgical debulking. New therapeutic approaches using immunotherapy via immune …