US Imaging of Tumor Angiogenesis with Microbubbles Targeted to Vascular Endothelial Growth Factor Receptor Type 2 in Mice1
…, K Chen, O Gheysens, M Rodriguez-Porcel, AM Lutz… - Radiology, 2008 - pubs.rsna.org
Purpose: To prospectively evaluate contrast material–enhanced ultrasonography (US) with
microbubbles targeted to vascular endothelial growth factor receptor type 2 (VEGFR2) for …
microbubbles targeted to vascular endothelial growth factor receptor type 2 (VEGFR2) for …
Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo
JK Willmann, AM Lutz, R Paulmurugan, MR Patel… - Radiology, 2008 - pubs.rsna.org
Purpose To develop and validate a dual-targeted ultrasonographic (US) imaging agent with
microbubbles (MBs) that attaches to both vascular endothelial growth factor (VEGF) receptor …
microbubbles (MBs) that attaches to both vascular endothelial growth factor (VEGF) receptor …
Ultrasound molecular imaging with BR55 in patients with breast and ovarian lesions: first-in-human results
Purpose We performed a first-in-human clinical trial on ultrasound molecular imaging (USMI)
in patients with breast and ovarian lesions using a clinical-grade contrast agent (kinase …
in patients with breast and ovarian lesions using a clinical-grade contrast agent (kinase …
Ultrasound and microbubble mediated therapeutic delivery: Underlying mechanisms and future outlook
Beyond the emerging field of oncological ultrasound molecular imaging, the recent significant
advancements in ultrasound and contrast agent technology have paved the way for …
advancements in ultrasound and contrast agent technology have paved the way for …
Targeted Microbubbles for Imaging Tumor Angiogenesis: Assessment of Whole-Body Biodistribution with Dynamic Micro-PET in Mice1
JK Willmann, Z Cheng, C Davis, AM Lutz, ML Schipper… - Radiology, 2008 - pubs.rsna.org
Purpose: To evaluate in vivo whole-body biodistribution of microbubbles (MBs) targeted to
tumor angiogenesis–related vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) …
tumor angiogenesis–related vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) …
Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides
…, RH Kimura, N Deshpande, AM Lutz… - Journal of Nuclear …, 2010 - jnm.snmjournals.org
Targeted contrast-enhanced ultrasound imaging is increasingly being recognized as a powerful
imaging tool for the detection and quantification of tumor angiogenesis at the molecular …
imaging tool for the detection and quantification of tumor angiogenesis at the molecular …
Early diagnosis of ovarian carcinoma: is a solution in sight?
AM Lutz, JK Willmann, CW Drescher, P Ray… - Radiology, 2011 - pubs.rsna.org
Ovarian cancer is the most lethal of the gynecologic malignancies. Because ovarian cancer
symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well …
symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well …
Breast cancer detection by B7-H3–targeted ultrasound molecular imaging
Ultrasound complements mammography as an imaging modality for breast cancer detection,
especially in patients with dense breast tissue, but its utility is limited by low diagnostic …
especially in patients with dense breast tissue, but its utility is limited by low diagnostic …
Cancer screening: a mathematical model relating secreted blood biomarker levels to tumor sizes
AM Lutz, JK Willmann, FV Cochran, P Ray… - PLoS …, 2008 - journals.plos.org
Background Increasing efforts and financial resources are being invested in early cancer
detection research. Blood assays detecting tumor biomarkers promise noninvasive and …
detection research. Blood assays detecting tumor biomarkers promise noninvasive and …
Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from …
…, B Weber, S Scheidegger, A Lutz… - Journal of Nuclear …, 2004 - jnm.snmjournals.org
Differentiation between posttherapy radiation necrosis and recurrent tumor in humans with
brain tumor is still a difficult diagnostic task. The new PET tracers 18 F-fluoro-ethyl-l-tyrosine (…
brain tumor is still a difficult diagnostic task. The new PET tracers 18 F-fluoro-ethyl-l-tyrosine (…