User profiles for Adrian-Bogdan Tigu
Tigu Adrian BogdanMedFuture Research Center for Advanced Medicine, “Iuliu Hatieganu” UMPh, Cluj-Napoca … Verified email at umfcluj.ro Cited by 800 |
An emerging class of long non-coding RNA with oncogenic role arises from the snoRNA host genes
The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which
are reported in many studies as being overexpressed in various cancers. With very few …
are reported in many studies as being overexpressed in various cancers. With very few …
Molecular links between central obesity and breast cancer
Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development and …
incidence and mortality. In recent years, the negative role of obesity during BC development and …
Therapeutic advances of targeting receptor tyrosine kinases in cancer
Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained
significant clinical attention in oncology due to their central role in cancer pathogenesis. Genetic …
significant clinical attention in oncology due to their central role in cancer pathogenesis. Genetic …
The role of epigenetic modifier mutations in peripheral T-cell lymphomas
AB Tigu, A Bancos - Current Issues in Molecular Biology, 2023 - mdpi.com
Peripheral T-cell lymphomas (PTCLs) are a group of diseases with a low incidence, high
degree of heterogeneity, and a dismal prognosis in most cases. Because of the low incidence …
degree of heterogeneity, and a dismal prognosis in most cases. Because of the low incidence …
Design and preclinical testing of an anti‐CD41 CAR T cell for the treatment of acute megakaryoblastic leukaemia
AB Tigu, CS Constantinescu… - Journal of Cellular …, 2023 - Wiley Online Library
… Adrian Bogdan Tigu and Catalin Constantinescu contributed equally to the current manuscript.
Catalin Constantinescu is funded by an internal grant of the Iuliu Hatieganu University – …
Catalin Constantinescu is funded by an internal grant of the Iuliu Hatieganu University – …
Nanoscale delivery systems for microRNAs in cancer therapy
…, D Gulei, AA Zimta, A Onaciu, L Magdo, AB Tigu… - Cellular and Molecular …, 2020 - Springer
Concomitant with advances in research regarding the role of miRNAs in sustaining
carcinogenesis, major concerns about their delivery options for anticancer therapies have been …
carcinogenesis, major concerns about their delivery options for anticancer therapies have been …
Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells
C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today’s society, the study of compounds isolated from natural sources …
malignancy affects today’s society, the study of compounds isolated from natural sources …
Phytochemical Analysis and In Vitro Effects of Allium fistulosum L. and Allium sativum L. Extracts on Human Normal and Tumor Cell Lines: A Comparative Study
Allium sativum L. (garlic bulbs) and Allium fistulosum L. (Welsh onion leaves) showed
quantitative differences of identified compounds: allicin and alliin (380 µg/mL and 1410 µg/mL in …
quantitative differences of identified compounds: allicin and alliin (380 µg/mL and 1410 µg/mL in …
Inhibitory effect of CAPE and kaempferol in colon cancer cell lines—possible implications in new therapeutic strategies
…, A Barbat, A Moldovan, C Moldovan, AB Tigu… - International journal of …, 2019 - mdpi.com
Background: Phytochemicals are natural compounds synthesized as secondary metabolites
in plants and represent an important source of molecules with therapeutic applications. …
in plants and represent an important source of molecules with therapeutic applications. …
The synergistic antitumor effect of 5-fluorouracil combined with allicin against lung and colorectal carcinoma cells
5-fluorouracil (5-FU) is an anticancer drug used to inhibit the proliferation of many different
tumor cells. Since severe events are associated with this compound, its combination with …
tumor cells. Since severe events are associated with this compound, its combination with …