[HTML][HTML] A stem cell niche dominance theorem
O Wolkenhauer, DK Shibata, MD Mesarović - BMC Systems Biology, 2011 - Springer
Background Multilevelness is a defining characteristic of complex systems. For example, in
the intestinal tissue the epithelial lining is organized into crypts that are maintained by a
niche of stem cells. The behavior of the system'as a whole'is considered to emerge from the
functioning and interactions of its parts. What we are seeking here is a conceptual
framework to demonstrate how the" fate" of intestinal crypts is an emergent property that
inherently arises from the complex yet robust underlying biology of stem cells. Results We …
the intestinal tissue the epithelial lining is organized into crypts that are maintained by a
niche of stem cells. The behavior of the system'as a whole'is considered to emerge from the
functioning and interactions of its parts. What we are seeking here is a conceptual
framework to demonstrate how the" fate" of intestinal crypts is an emergent property that
inherently arises from the complex yet robust underlying biology of stem cells. Results We …
[CITATION][C] A stem cell niche dominance theorem.
O Wolkenhauer, D Shibata… - Journal of Stem Cells & …, 2010 - europepmc.org
A stem cell niche dominance theorem. - Abstract - Europe PMC … A stem cell niche
dominance theorem. … Journal of Stem Cells & Regenerative Medicine, 23 Oct 2010, 6(2):98 …
dominance theorem. … Journal of Stem Cells & Regenerative Medicine, 23 Oct 2010, 6(2):98 …
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