A statistical method for correlating tRNA sequence with amino acid specificity

T Atilgan, HB Nicholas Jr, WH McClain - Nucleic acids research, 1986 - academic.oup.com
A statistical method for finding the nucleotide positions in tRNA sequences that correlate
with amino acid specificity has been developed. The procedure involves finding the subset
of nucleotide positions and groups of positions where the marginal density of one amino
acid tRNA class does not overlap that of any other amino acid class. The procedure is an
application of a statistical method known as the Expectation Maximization algorithm.

[PDF][PDF] A statistical method for correlating tRNA sequence with amino add specificity

HBN Taskin Atilgan Jr, WH McCIain - Citeseer
ABSTRACT A statistical method for finding the nucleotide positions in tRNA sequences that
correlate with amino acid specificity has been developed. The procedure involves finding
the subset of nucleotide positions and groups of positions where the marginal density of one
amino acid tRNA class does not overlap that of any other amino acid class. The procedure is
an application of a statistical method known as the Expectation Maximization algorithm.
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