Voltage-gated Ca e+ channels control the entry of Ca e+ ions across the surface membrane
of neurons and other cells and thereby influence electrical activity and diverse cellular …

A curious property of excitatory synapses in the hippocampus and some other neural tissues
is that when they are heavily used, they undergo a long lasting increase in their efficacy …

The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries
out diverse signaling tasks in both the central and peripheral nervous systems. Whereas …

Long-term potentiation (LTP) of synaptic transmission is a widely studied model of neuronal
plasticity. The induction of LTP is known to require processes in the postsynaptic neuron …

Experiments using intracellular recording techniques were performed on rat hippocampal
neurones in vitro, to study the discharge properties of these cells. When CA 1 pyramidal …

The hippocampus, as well as a variety of other brain regions, is known to receive a diffuse
projection of noradrenaline (NA) containing fibres which originates in the brain stem1–4 …

Long-term potentiation (LTP) of synaptic transmission in the hippocampus is a much-studied
example of synaptic plasticity1, 2. Although the role of N-methyl-D-aspartate (NMDA) …

The long-lasting increase in synaptic strength known as long-term potentiation has been
advanced as a potential physiological mechanism for many forms of both developmental …

A slow muscarinic EPSP, accompanied by an increase in membrane input resistance, can
be elicited in hippocampal CA1 pyramidal cells in vitro by electrical stimulation of cholinergic …

Protein kinase C (PKC), a calcium-dependent phospholipid-sensitive kinase which is
selectively activated by phorbol esters, is thought to play an important role in several cellular …