The plasma membrane is considered to be the primary site of injury when plant cells are
subjected to extracellular freezing. In order for plants or plant cells to acquire freezing …

Pericytes are unique, multi-functional mural cells localized at the abluminal side of the
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …

The stereotypical spread of pathological protein inclusions and clinicopathological
heterogeneity are well described in neurodegenerative diseases. Accumulating evidence …

Although the chromosomal localization (9q34) of the gene encoding the human form of
ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13) …

Prostate cancer often relapses during androgen‐depletion therapy, even under conditions in
which a drastic reduction of circulating androgens is observed. There is some evidence that …

Maximum freezing tolerance of Arabidopsis thaliana L. Heyn (Columbia) was attained after 1
week of cold acclimation at 2 [deg] C. During this time, there were significant changes in …

Background In a single-group, phase 1b trial, avelumab plus axitinib resulted in objective
responses in patients with advanced renal-cell carcinoma. This phase 3 trial involving …

Background Darolutamide is a potent androgen-receptor inhibitor that has been associated
with increased overall survival among patients with nonmetastatic, castration-resistant …

Background A phase 2 trial showed improved progression-free survival for atezolizumab
plus bevacizumab versus sunitinib in patients with metastatic renal cell carcinoma who …

Background Survival outcomes are poor for patients with metastatic urothelial carcinoma
who receive standard, first-line, platinum-based chemotherapy. We assessed the overall …