Neurons are generally considered to communicate information by increasing or decreasing
their firing rate. However, in principle, they could in addition convey messages by using …

The inferior olive, which provides the climbing fibers to Purkinje cells in the cerebellar cortex,
has been implicated in various functions, such as learning and timing of movements, and …

The rodent whisker system is widely used as a model system for investigating sensorimotor
integration, neural mechanisms of complex cognitive tasks, neural development, and …

Absence of functional FMRP causes Fragile X syndrome. Abnormalities in synaptic
processes in the cerebral cortex and hippocampus contribute to cognitive deficits in Fragile …

Cerebellar long-term depression (LTD) is a model system for neuronal information storage
that has an absolute requirement for activation of protein kinase C (PKC). It has been …

OBJECTIVES: Evaluation of neurocognitive function of school-age children with HIV.
DESIGN: Cross-sectional observational study. METHODS: Twenty-two children (median age …

Lack of fragile X mental retardation protein (FMRP) causes Fragile X Syndrome, the most
common form of inherited mental retardation. FMRP is an RNA-binding protein and is a …

Highly sensitive techniques, such as PCR, have greatly improved the detection of respiratory
viruses. However, the sensitivity of PCR tests also complicates clinical interpretation, as the …

Mammals can be trained to make a conditioned movement at a precise time, which is
correlated to the interval between the conditioned stimulus and unconditioned stimulus …

Cerebellar motor learning is required to obtain procedural skills. Studies have provided
supportive evidence for a potential role of kinase-mediated long-term depression (LTD) at …