User profiles for "author:He Y"

Yudong He

- Verified email at alleninstitute.org - Cited by 33586

Yuchen HE

- Verified email at illinois.edu - Cited by 3747

[PDF][PDF] Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal… - Autophagy, 2008 - Taylor & Francis
Research in autophagy continues to accelerate, 1 and as a result many new scientists are
entering the field. Accordingly, it is important to establish a standard set of criteria for …

The NLRP3 inflammasome: an overview of mechanisms of activation and regulation

N Kelley, D Jeltema, Y Duan, Y He - International journal of molecular …, 2019 - mdpi.com
The NLRP3 inflammasome is a critical component of the innate immune system that
mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in …

Comparison of next‐generation sequencing systems

L Liu, Y Li, S Li, N Hu, Y He, R Pong… - BioMed research …, 2012 - Wiley Online Library
With fast development and wide applications of next‐generation sequencing (NGS)
technologies, genomic sequence information is within reach to aid the achievement of goals …

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

YF He, BZ Li, Z Li, P Liu, Y Wang, Q Tang, J Ding, Y Jia… - Science, 2011 - science.org
The prevalent DNA modification in higher organisms is the methylation of cytosine to 5-
methylcytosine (5mC), which is partially converted to 5-hydroxymethylcytosine (5hmC) by …

Changing cancer survival in China during 2003–15: a pooled analysis of 17 population-based cancer registries

H Zeng, W Chen, R Zheng, S Zhang, JS Ji… - The Lancet Global …, 2018 - thelancet.com
Summary Background From 2003 to 2005, standardised 5-year cancer survival in China
was much lower than in developed countries and varied substantially by geographical area …

TBtools: an integrative toolkit developed for interactive analyses of big biological data

C Chen, H Chen, Y Zhang, HR Thomas, MH Frank… - Molecular plant, 2020 - cell.com
The rapid development of high-throughput sequencing techniques has led biology into the
big-data era. Data analyses using various bioinformatics tools rely on programming and …

Expression of elevated levels of pro‐inflammatory cytokines in SARS‐CoV‐infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis …

L He, Y Ding, Q Zhang, X Che, Y He… - The Journal of …, 2006 - Wiley Online Library
The authors have previously shown that acute lung injury (ALI) produces a wide spectrum of
pathological processes in patients who die of severe acute respiratory syndrome (SARS) …

Gpt-4 technical report

J Achiam, S Adler, S Agarwal, L Ahmad… - arXiv preprint arXiv …, 2023 - arxiv.org
We report the development of GPT-4, a large-scale, multimodal model which can accept
image and text inputs and produce text outputs. While less capable than humans in many …

Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China

Y Guan, BJ Zheng, YQ He, XL Liu, ZX Zhuang… - Science, 2003 - science.org
A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome
(SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal …

Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a …

TSK Mok, YL Wu, I Kudaba, DM Kowalski, BC Cho… - The Lancet, 2019 - thelancet.com
Background First-line pembrolizumab monotherapy improves overall and progression-free
survival in patients with untreated metastatic non-small-cell lung cancer with a programmed …