Data on comprehensive population-based surveillance of antimicrobial resistance is lacking.
In low-and middle-income countries, the challenges are high due to weak laboratory …

The OXA β-lactamases were among the earliest β-lactamases detected; however, these
molecular class D β-lactamases were originally relatively rare and always plasmid …

Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

Acinetobacter baumannii is a leading cause of nosocomial infections due to its increased
antibiotic resistance and virulence. The ability of A. baumannii to form biofilms contributes to …

The rapid expansion of Acinetobacter baumannii clinical isolates exhibiting resistance to
carbapenems and most or all available antibiotics during the last decade is a worrying …

Over recent decades, the pipeline of antibiotics acting against Gram‐negative bacteria is
running dry, as most discovered candidate antibiotics suffer from insufficient potency …

Antibiotic resistance is a major global public health concern. Acinetobacter baumannii is a
nosocomial pathogen that has emerged as a global threat because of its high levels of …

Macrolide resistance mechanisms can be target-based with a change in a 23S ribosomal
RNA (rRNA) residue or a mutation in ribosomal protein L4 or L22 affecting the ribosome's …

Acinetobacter spp. are Gram-negative bacteria that have become one of the most difficult
pathogens to treat. The species A. baumannii, largely unknown 30 years ago, has risen to …

Acinetobacter baumannii is an opportunistic pathogen, especially in intensive care units,
and multidrug-resistant isolates have increasingly been reported during the last decade …