Overview: The Ongoing Threat of Antimicrobial Resistance

Richard R Watkins; Robert A Bonomo

doi:10.1016/j.idc.2020.04.002

Overview: The Ongoing Threat of Antimicrobial Resistance

Infect Dis Clin North Am. 2020 Dec;34(4):649-658. doi: 10.1016/j.idc.2020.04.002. Epub 2020 Sep 30.

Authors

Richard R Watkins¹, Robert A Bonomo²

Affiliations

¹ Division of Infectious Diseases, Cleveland Clinic Akron General, Akron, OH, USA; Department of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA. Electronic address: [email protected].
² Medical Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA; Case VA Center for Antimicrobial Resistance and Epidemiology (Case VA-CARES), Case Western Reserve University, Cleveland, OH, USA.

PMID: 33011053
DOI: 10.1016/j.idc.2020.04.002

Abstract

The effectiveness of antibiotics continues to erode because of the relentless spread of antimicrobial resistance (AMR). Public and private foundations, professional organizations, and international health agencies recognize the threat posed by AMR and have issued calls for action. One of the main drivers of AMR is overprescription of antibiotics, both in human and in veterinary medicine. The One Health concept is a response from a broad group of stakeholders to counter the global health threat posed by AMR. In this article, we discuss current trends in AMR and suggest strategies to mitigate its ongoing dissemination.

Keywords: Antibiotics; Antimicrobial resistance; Public health.

Publication types

Review

MeSH terms

Animals
Anti-Infective Agents / economics*
Antimicrobial Stewardship
Centers for Disease Control and Prevention, U.S.
Drug Prescriptions
Drug Resistance, Microbial*
Global Health
Gross Domestic Product
Humans
One Health*
United States

Substances

Anti-Infective Agents