Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Affiliations

• ¹ Department of Biological Sciences, Columbia University, 550 West 120(th) Street, MC 4846, New York, NY 10027, USA; Department of Chemistry, Columbia University, 550 West 120(th) Street, MC 4846, New York, NY 10027, USA. Electronic address: [email protected].
• ² Institute of Developmental Genetics, Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH), München, Germany.
• ³ Department of Critical Care Medicine, Safar Center for Resuscitation Research and Center for Free Radical and Antioxidant Health, University of Pittsburgh and Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
• ⁴ The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
• ⁵ Department of Biology, Stanford University, Stanford, CA, USA.
• ⁶ Institute for Experimental Cancer Research in Pediatrics, Goethe-University Frankfurt, German Cancer Consortium (DKTK), partner site Frankfurt, German Cancer Research Center (DKFZ), Heidelberg, Germany.
• ⁷ Ludwig-Maximilians University of Munich, Physiological Genomics, Biomedical Center (BMC), Planegg-Martinsried, Germany; Institute for Stem Cell Research, Helmholtz Center Munich at the Biomedical Center (BMC), Grosshaderner Strasse 9, 82152 Planegg-Martinsried, Germany.
• ⁸ Department of Molecular, Cellular and Developmental Biology and Department of Chemistry, Yale University, New Haven, CT 06511, USA; Microbial Sciences Institute, Yale University, West Haven, CT 06516, USA.
• ⁹ Center for Free Radical and Antioxidant Health, Departments of Environmental Health, Pharmacology and Chemical Biology, Chemistry, Radiation Oncology, University of Pittsburgh, Pittsburgh, PA, USA.
• ¹⁰ Collaborative Medicinal Development, LLC, Sausalito, CA, USA.
• ¹¹ Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• ¹² Department of Internal Medicine III, Division of Nephrology, University Hospital Carl Gustav Carus at Technische Universität Dresden, Dresden, Germany.
• ¹³ Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA, USA.
• ¹⁴ Ono Pharma USA, Lawrenceville, NJ 08648, USA.
• ¹⁵ Instituto de Investigaciones Biológicas, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Mar del Plata, 7600 Mar del Plata, Argentina.
• ¹⁶ Flagship Pioneering, Cambridge, MA, USA.
• ¹⁷ Department of Cell Systems and Anatomy, University of Texas Health Science Center, San Antonio, TX, USA.
• ¹⁸ Division of Cancer Biology, National Cancer Institute, NIH, Rockville, MD 20850, USA.
• ¹⁹ The Third Affiliated Hospital, Center for DAMP Biology, Key Laboratory for Major Obstetric Diseases of Guangdong Province, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Protein Modification and Degradation Laboratory, Guangzhou Medical University, Guangzhou, Guangdong, China; Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
• ²⁰ Department of Medicine, University of Connecticut Health Center, Farmington, CT, USA.
• ²¹ Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT, USA.
• ²² Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya, Japan.
• ²³ Department of Chemistry, New York University, New York, NY, USA.
• ²⁴ Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ, USA.