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Integrated epigenomic exposure signature discovery. Epigenomics. 2024 Sep 03; 1-17.
Schuetter J, Minard-Smith A, Hill B, Beare JL, Vornholt A, Burke TW, Murugan V, Smith AK, Chandrasekaran T, Shamma HJ, Kahaian SC, Fillinger KL, S Amper MA, Cheng WS, Ge Y, George MC, Guevara K, Lovette-Okwara N, Mahajan A, Marjanovic N, Mendelev N, Fowler VG, McClain MT, Miller CM, Mofsowitz S, Nair VD, Nudelman G, Evans TG, Castellino F, Ramos I, Rirak S, Ruf-Zamojski F, Seenarine N, Soares-Shanoski A, Vangeti S, Vasoya M, Yu X, Zaslavsky E, Ndhlovu LC, Corley MJ, Bowler S, Deeks SG, Letizia AG, Sealfon SC, Woods CW, Spurbeck RR. PMID: 39225561.
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PubMed Mentions:
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Early biological markers of post-acute sequelae of SARS-CoV-2 infection. Nat Commun. 2024 Aug 29; 15(1):7466.
Lu S, Peluso MJ, Glidden DV, Davidson MC, Lugtu K, Pineda-Ramirez J, Tassetto M, Garcia-Knight M, Zhang A, Goldberg SA, Chen JY, Fortes-Cobby M, Park S, Martinez A, So M, Donovan A, Viswanathan B, Hoh R, Donohue K, McIlwain DR, Gaudiliere B, Anglin K, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deeks SG, Briggs-Hagen M, Andino R, Midgley CM, Martin JN, Saydah S, Kelly JD. PMID: 39198441; PMCID: PMC11358427.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Galectin-9 Levels as a Potential Predictor of Intact HIV Reservoir Decay. J Infect Dis. 2024 Aug 28.
Serrano-Villar S, Gala A, Bacchetti P, Hoh R, di Germanio C, Cohn LB, Henrich TJ, Hunt PW, Laird GM, Pillai SK, Deeks SG, Peluso MJ. PMID: 39207259.
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PubMed Mentions:
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HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA. Proc Natl Acad Sci U S A. 2024 Sep 03; 121(36):e2405210121.
Capoferri AA, Wiegand A, Hong F, Jacobs JL, Spindler J, Musick A, Bale MJ, Shao W, Sobolewski MD, Cillo AR, Luke BT, Fennessey CM, Gorelick RJ, Hoh R, Halvas EK, Deeks SG, Coffin JM, Mellors JW, Kearney MF. PMID: 39190360.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Mechanisms and efficacy of small molecule "latency promoting agents" to inhibit HIV reactivation ex vivo. JCI Insight. 2024 Aug 20.
Janssens J, Kim P, Kim SJ, Wedrychowski A, Kadiyala GN, Hunt PW, Deeks SG, Wong JK, Yukl SA. PMID: 39163135.
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PubMed Mentions: Fields:
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Prediction of differential Gag versus Env responses to a mosaic HIV-1 vaccine regimen by HLA class I alleles. J Virol. 2024 Jul 24; e0028124.
Nelson GW, van Duijn J, Yuki Y, Pau MG, Tomaka F, Lavreys L, DeRosa SC, McElrath MJ, Kirk GD, Michael NL, Haas DW, Deeks SG, Wolinsky S, Walker B, Barouch DH, Stieh D, Carrington M. PMID: 39046263.
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PubMed Mentions: Fields:
Translation:
HumansCellsCTClinical Trials
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Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection. Sci Transl Med. 2024 Jul 03; 16(754):eadk3295.
Peluso MJ, Ryder D, Flavell RR, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez AE, Buitrago M, Tai V, Shrestha U, Lu S, Goldberg SA, Dalhuisen T, Vasquez JJ, Durstenfeld MS, Hsue PY, Kelly JD, Kumar N, Martin JN, Gambhir A, Somsouk M, Seo Y, Deeks SG, Laszik ZG, VanBrocklin HF, Henrich TJ. PMID: 38959327; PMCID: PMC11337933.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Circulating immune and plasma biomarkers of time to HIV rebound in HIV controllers treated with vesatolimod. Front Immunol. 2024; 15:1405348.
Abdel-Mohsen M, Deeks S, Giron L, Hong KY, Goldman A, Zhang L, Huang SSY, Verrill D, Guo S, Selzer L, de Vries CR, Vendrame E, SenGupta D, Wallin JJ, Cai Y. PMID: 38979421; PMCID: PMC11229794.
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PubMed Mentions: Fields:
Translation:
HumansCellsCTClinical Trials
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HIV rebound in HIV controllers is associated with a specific fecal microbiome profile. Eur J Immunol. 2024 Aug; 54(8):e2350809.
Cai Y, Podlaha O, Deeks SG, Brinson C, Ramgopal MN, DeJesus E, Mills A, Shalit P, Abdel-Mohsen M, Zhang L, de Vries CR, Vendrame E, SenGupta D, Wallin JJ. PMID: 38727191.
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Translation:
HumansCells
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AMPLON: Amplifying DNA with Multiarm Priming and Looping Optimization of Nucleic Acid. Adv Mater. 2024 Jul; 36(28):e2311634.
Doganay MT, Roman E, Hujer AM, Bonomo RA, Deeks SG, Kuritzkes DR, Draz MS. PMID: 38657970; PMCID: PMC11239297.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Autologous neutralizing antibody responses after antiretroviral therapy in acute and early HIV-1. J Clin Invest. 2024 Apr 23; 134(11).
Whitehill GD, Joy J, Marino FE, Krause R, Mallick S, Courtney H, Park K, Carey J, Hoh R, Hartig H, Pae V, Sarvadhavabhatla S, Donaire S, Deeks SG, Lynch RM, Lee SA, Bar KJ. PMID: 38652564; PMCID: PMC11142743.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsCTClinical Trials
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Differential susceptibility of cells infected with defective and intact HIV proviruses to killing by obatoclax and other small molecules. AIDS. 2024 07 15; 38(9):1281-1291.
Kadiyala GN, Telwatte S, Wedrychowski A, Janssens J, Kim SJ, Kim P, Deeks S, Wong JK, Yukl SA. PMID: 38626436; PMCID: PMC11216394.
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PubMed Mentions: Fields:
Translation:
HumansCells
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High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen. Front Immunol. 2024; 15:1378040.
Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. PMID: 38698866; PMCID: PMC11064812.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Long COVID and post-acute sequelae of SARS-CoV-2 pathogenesis and treatment: A Keystone Symposia report. Ann N Y Acad Sci. 2024 May; 1535(1):31-41.
Durstenfeld MS, Weiman S, Holtzman M, Blish C, Pretorius R, Deeks SG. PMID: 38593220.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Plasma-based antigen persistence in the post-acute phase of COVID-19. Lancet Infect Dis. 2024 Jun; 24(6):e345-e347.
Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Chang Song C, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli MA, Glidden DV, Henrich TJ, Kelly JD, Deeks SG, Walt DR, Martin JN. PMID: 38604216.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Rapid Biphasic Decay of Intact and Defective HIV DNA Reservoir During Acute Treated HIV Disease. medRxiv. 2024 Mar 28.
Barbehenn A, Shi L, Shao J, Hoh R, Hartig HM, Pae V, Sarvadhavabhatla S, Donaire S, Sheikhzadeh C, Milush J, Laird GM, Mathias M, Ritter K, Peluso M, Martin J, Hecht F, Pilcher C, Cohen SE, Buchbinder S, Havlir D, Gandhi M, Henrich TJ, Hatano H, Wang J, Deeks SG, Lee SA. PMID: 38585951; PMCID: PMC10996734.
View in:
PubMed Mentions:
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Author Correction: Exploring synergies between B- and T-cell vaccine approaches to optimize immune responses against HIV-workshop report. NPJ Vaccines. 2024 Mar 14; 9(1):61.
Maciel M, Amara RR, Bar KJ, Crotty S, Deeks SG, Duplessis C, Gaiha G, McElrath MJ, McMichael A, Palin A, Rutishauser R, Shapiro S, Smiley ST, D'Souza MP. PMID: 38485736; PMCID: PMC10940590.
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PubMed Mentions:
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Advancing HIV cure research in low- and middle-income countries requires empowerment of the next generation of scientists. J Virus Erad. 2024 Mar; 10(1):100364.
Tatoud R, Jones RB, Dong K, Ndung'u T, Deeks S, Tiemessen CT. PMID: 38559321; PMCID: PMC10979089.
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PubMed Mentions:
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High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen. bioRxiv. 2024 Mar 06.
Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. PMID: 36711855; PMCID: PMC9881994.
View in:
PubMed Mentions:
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Exploring synergies between B- and T-cell vaccine approaches to optimize immune responses against HIV-workshop report. NPJ Vaccines. 2024 Feb 21; 9(1):39.
Maciel M, Amara RR, Bar KJ, Crotty S, Deeks SG, Duplessis C, Gaiha G, McElrath MJ, McMichael A, Palin A, Rutishauser R, Shapiro S, Smiley ST, D'Souza MP. PMID: 38383616; PMCID: PMC10881492.
View in:
PubMed Mentions:
1
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Mild HIV-specific selective forces overlaying natural CD4+ T cell dynamics explain the clonality and decay dynamics of HIV reservoir cells. medRxiv. 2024 Feb 15.
Reeves DB, Rigau DN, Romero A, Zhang H, Simonetti FR, Varriale J, Hoh R, Zhang L, Smith KN, Montaner LJ, Rubin LH, Gange SJ, Roan NR, Tien PC, Margolick JB, Peluso MJ, Deeks SG, Schiffer JT, Siliciano JD, Siliciano RF, Antar AAR. PMID: 38405967; PMCID: PMC10888981.
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PubMed Mentions:
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Predictors of HIV rebound differ by timing of antiretroviral therapy initiation. JCI Insight. 2024 Feb 08; 9(3).
Li JZ, Melberg M, Kittilson A, Abdel-Mohsen M, Li Y, Aga E, Bosch RJ, Wonderlich ER, Kinslow J, Giron LB, Di Germanio C, Pilkinton M, MacLaren L, Keefer M, Fox L, Barr L, Acosta E, Ananworanich J, Coombs R, Mellors J, Deeks S, Gandhi RT, Busch M, Landay A, Macatangay B, Smith DM, AIDS Clinical Trials Group A5345 Study Team. PMID: 38329130; PMCID: PMC10967395.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells. Nat Immunol. 2024 Mar; 25(3):462-470.
Board NL, Yuan Z, Wu F, Moskovljevic M, Ravi M, Sengupta S, Mun SS, Simonetti FR, Lai J, Tebas P, Lynn K, Hoh R, Deeks SG, Siliciano JD, Montaner LJ, Siliciano RF. PMID: 38278966; PMCID: PMC10907297.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Impact of HLA class I functional divergence on HIV control. Science. 2024 01 19; 383(6680):319-325.
Viard M, O'hUigin C, Yuki Y, Bashirova AA, Collins DR, Urbach JM, Wolinsky S, Buchbinder S, Kirk GD, Goedert JJ, Michael NL, Haas DW, Deeks SG, Walker BD, Yu X, Carrington M. PMID: 38236978.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2. Nat Immunol. 2024 Feb; 25(2):218-225.
Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young KC, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. PMID: 38212464; PMCID: PMC10834368.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Association of nirmatrelvir for acute SARS-CoV-2 infection with subsequent Long COVID symptoms in an observational cohort study. J Med Virol. 2024 01; 96(1):e29333.
Durstenfeld MS, Peluso MJ, Lin F, Peyser ND, Isasi C, Carton TW, Henrich TJ, Deeks SG, Olgin JE, Pletcher MJ, Beatty AL, Marcus GM, Hsue PY. PMID: 38175151; PMCID: PMC10786003.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Plasma-based antigen persistence in the post-acute phase of SARS-CoV-2 infection. medRxiv. 2023 Dec 29.
Peluso MJ, Swank ZN, Goldberg SA, Lu S, Dalhuisen T, Borberg E, Senussi Y, Luna MA, Song CC, Clark A, Zamora A, Lew M, Viswanathan B, Huang B, Anglin K, Hoh R, Hsue PY, Durstenfeld MS, Spinelli MA, Glidden DV, Henrich TJ, Daniel Kelly J, Deeks SG, Walt DR, Martin JN. PMID: 37961239; PMCID: PMC10635183.
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PubMed Mentions:
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A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size. PLoS Pathog. 2023 Nov; 19(11):e1011114.
Dwivedi AK, Gornalusse GG, Siegel DA, Barbehenn A, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Reppetti J, Vo PM, Levy CN, Roychoudhury P, Jerome KR, Hladik F, Henrich TJ, Deeks SG, Lee SA. PMID: 38019897; PMCID: PMC10712869.
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Translation:
HumansCells
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Viral and host mediators of non-suppressible HIV-1 viremia. Nat Med. 2023 Dec; 29(12):3212-3223.
Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Crain CR, Traunbauer AK, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, Giguel F, Lian X, Deo R, Gillespie E, Chishti R, Abrha S, Adams T, Siagian A, Dorazio D, Anderson PL, Deeks SG, Lederman MM, Yawetz S, Kuritzkes DR, Lichterfeld MD, Sieg S, Tsibris A, Carrington M, Brumme ZL, Castillo-Mancilla JR, Engelman AN, Gaiha GD, Li JZ. PMID: 37957382; PMCID: PMC10719098.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The breadth of the neutralizing antibody response to original SARS-CoV-2 infection is linked to the presence of Long COVID symptoms. J Med Virol. 2023 11; 95(11):e29216.
Buck AM, Deitchman AN, Takahashi S, Lu S, Goldberg SA, Bodansky A, Kung A, Hoh R, Williams MC, Kerbleski M, Maison DP, Deveau TM, Munter SE, Lombardo J, Wrin T, Petropoulos CJ, Durstenfeld MS, Hsue PY, Kelly JD, Greenhouse B, Martin JN, Deeks SG, Peluso MJ, Henrich TJ. PMID: 37988251; PMCID: PMC10754238.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency. Cell Rep. 2023 11 28; 42(11):113285.
Sperber HS, Raymond KA, Bouzidi MS, Ma T, Valdebenito S, Eugenin EA, Roan NR, Deeks SG, Winning S, Fandrey J, Schwarzer R, Pillai SK. PMID: 37910505; PMCID: PMC10838153.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Serotonin reduction in post-acute sequelae of viral infection. Cell. 2023 10 26; 186(22):4851-4867.e20.
Wong AC, Devason AS, Umana IC, Cox TO, Dohnalová L, Litichevskiy L, Perla J, Lundgren P, Etwebi Z, Izzo LT, Kim J, Tetlak M, Descamps HC, Park SL, Wisser S, McKnight AD, Pardy RD, Kim J, Blank N, Patel S, Thum K, Mason S, Beltra JC, Michieletto MF, Ngiow SF, Miller BM, Liou MJ, Madhu B, Dmitrieva-Posocco O, Huber AS, Hewins P, Petucci C, Chu CP, Baraniecki-Zwil G, Giron LB, Baxter AE, Greenplate AR, Kearns C, Montone K, Litzky LA, Feldman M, Henao-Mejia J, Striepen B, Ramage H, Jurado KA, Wellen KE, O'Doherty U, Abdel-Mohsen M, Landay AL, Keshavarzian A, Henrich TJ, Deeks SG, Peluso MJ, Meyer NJ, Wherry EJ, Abramoff BA, Cherry S, Thaiss CA, Levy M. PMID: 37848036; PMCID: PMC11227373.
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PubMed Mentions:
47 Fields:
Translation:
Humans
-
Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV. J Am Heart Assoc. 2023 10 17; 12(20):e030896.
Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Chenna A, Yee B, Winslow J, Petropoulos C, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. PMID: 37830367; PMCID: PMC10757521.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence. Nat Commun. 2023 10 02; 14(1):6145.
Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW. PMID: 37783718; PMCID: PMC10545742.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Nat Immunol. 2023 Oct; 24(10):1778.
Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. PMID: 37723351.
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PubMed Mentions: Fields:
-
Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1. Cell Rep. 2023 Sep 26; 42(9):113055.
Li Z, Deeks SG, Ott M, Greene WC. PMID: 37682714; PMCID: PMC10591912.
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PubMed Mentions: Fields:
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SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Nat Immunol. 2023 10; 24(10):1616-1627.
Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. PMID: 37667052.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
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The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy. J Clin Invest. 2023 09 01; 133(17).
McMyn NF, Varriale J, Fray EJ, Zitzmann C, MacLeod H, Lai J, Singhal A, Moskovljevic M, Garcia MA, Lopez BM, Hariharan V, Rhodehouse K, Lynn K, Tebas P, Mounzer K, Montaner LJ, Benko E, Kovacs C, Hoh R, Simonetti FR, Laird GM, Deeks SG, Ribeiro RM, Perelson AS, Siliciano RF, Siliciano JM. PMID: 37463049; PMCID: PMC10471168.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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SARS-CoV-2 Serology Across Scales: A Framework for Unbiased Estimation of Cumulative Incidence Incorporating Antibody Kinetics and Epidemic Recency. Am J Epidemiol. 2023 09 01; 192(9):1562-1575.
Takahashi S, Peluso MJ, Hakim J, Turcios K, Janson O, Routledge I, Busch MP, Hoh R, Tai V, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Greenhouse B, Rodríguez-Barraquer I. PMID: 37119030; PMCID: PMC10472487.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Reduced Exercise Capacity, Chronotropic Incompetence, and Early Systemic Inflammation in Cardiopulmonary Phenotype Long Coronavirus Disease 2019. J Infect Dis. 2023 08 31; 228(5):542-554.
Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, Martin JN, Lee YJ, Aras MA, Long CS, Grandis DJ, Deeks SG, Hsue PY. PMID: 37166076; PMCID: PMC10686699.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2. bioRxiv. 2023 Aug 04.
Yin K, Peluso MJ, Luo X, Thomas R, Shin MG, Neidleman J, Andrew A, Young K, Ma T, Hoh R, Anglin K, Huang B, Argueta U, Lopez M, Valdivieso D, Asare K, Deveau TM, Munter SE, Ibrahim R, Ständker L, Lu S, Goldberg SA, Lee SA, Lynch KL, Kelly JD, Martin JN, Münch J, Deeks SG, Henrich TJ, Roan NR. PMID: 36798286; PMCID: PMC9934605.
View in:
PubMed Mentions:
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Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19. medRxiv. 2023 Jul 31.
Peluso MJ, Ryder D, Flavell R, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez A, Buitrago M, Tai V, Shrestha U, Lu S, Goldberg SA, Dalhuisen T, Durstenfeld MS, Hsue PY, Kelly JD, Kumar N, Martin JN, Gambir A, Somsouk M, Seo Y, Deeks SG, Laszik ZG, VanBrocklin HF, Henrich TJ. PMID: 37577714; PMCID: PMC10418298.
View in:
PubMed Mentions:
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Adaptation of Droplet Digital PCR-Based HIV Transcription Profiling to Digital PCR and Association of HIV Transcription and Total or Intact HIV DNA. Viruses. 2023 07 22; 15(7).
Tumpach C, Rhodes A, Kim Y, Ong J, Liu H, Chibo D, Druce J, Williamson D, Hoh R, Deeks SG, Yukl SA, Roche M, Lewin SR, Telwatte S. PMID: 37515292; PMCID: PMC10384802.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection. Nature. 2023 Aug; 620(7972):128-136.
Augusto DG, Murdolo LD, Chatzileontiadou DSM, Sabatino JJ, Yusufali T, Peyser ND, Butcher X, Kizer K, Guthrie K, Murray VW, Pae V, Sarvadhavabhatla S, Beltran F, Gill GS, Lynch KL, Yun C, Maguire CT, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Vierra-Green CA, Spellman SR, Langton DJ, Dewar-Oldis MJ, Smith C, Barnard PJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Maiers M, Gras S, Hollenbach JA. PMID: 37468623; PMCID: PMC10396966.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Impact of misclassified defective proviruses on HIV reservoir measurements. Nat Commun. 2023 07 13; 14(1):4186.
Reeves DB, Gaebler C, Oliveira TY, Peluso MJ, Schiffer JT, Cohn LB, Deeks SG, Nussenzweig MC. PMID: 37443365; PMCID: PMC10345136.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis. EMBO J. 2023 08 15; 42(16):e114153.
Wang Y, Lifshitz L, Silverstein NJ, Mintzer E, Luk K, StLouis P, Brehm MA, Wolfe SA, Deeks SG, Luban J. PMID: 37382276; PMCID: PMC10425848.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Effect of Immune-Modulatory Interventions on Asymptomatic Cytomegalovirus Shedding During Suppressive Antiretroviral Therapy. J Infect Dis. 2023 06 28; 228(1):64-69.
Hastie E, Moser C, Sun X, Lennox J, Hsue PY, Bosch RJ, Deeks S, Meneses MV, Lederman MM, Hunt P, Henrich TJ, Marconi VC, Gianella S. PMID: 36881933; PMCID: PMC10490531.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design. PLoS One. 2023; 18(6):e0286297.
Horwitz LI, Thaweethai T, Brosnahan SB, Cicek MS, Fitzgerald ML, Goldman JD, Hess R, Hodder SL, Jacoby VL, Jordan MR, Krishnan JA, Laiyemo AO, Metz TD, Nichols L, Patzer RE, Sekar A, Singer NG, Stiles LE, Taylor BS, Ahmed S, Algren HA, Anglin K, Aponte-Soto L, Ashktorab H, Bassett IV, Bedi B, Bhadelia N, Bime C, Bind MC, Black LJ, Blomkalns AL, Brim H, Castro M, Chan J, Charney AW, Chen BK, Chen LQ, Chen P, Chestek D, Chibnik LB, Chow DC, Chu HY, Clifton RG, Collins S, Costantine MM, Cribbs SK, Deeks SG, Dickinson JD, Donohue SE, Durstenfeld MS, Emery IF, Erlandson KM, Facelli JC, Farah-Abraham R, Finn AV, Fischer MS, Flaherman VJ, Fleurimont J, Fonseca V, Gallagher EJ, Gander JC, Gennaro ML, Gibson KS, Go M, Goodman SN, Granger JP, Greenway FL, Hafner JW, Han JE, Harkins MS, Hauser KSP, Heath JR, Hernandez CR, Ho O, Hoffman MK, Hoover SE, Horowitz CR, Hsu H, Hsue PY, Hughes BL, Jagannathan P, James JA, John J, Jolley S, Judd SE, Juskowich JJ, Kanjilal DG, Karlson EW, Katz SD, Kelly JD, Kelly SW, Kim AY, Kirwan JP, Knox KS, Kumar A, Lamendola-Essel MF, Lanca M, Lee-Lannotti JK, Lefebvre RC, Levy BD, Lin JY, Logarbo BP, Logue JK, Longo MT, Luciano CA, Lutrick K, Malakooti SK, Mallett G, Maranga G, Marathe JG, Marconi VC, Marshall GD, Martin CF, Martin JN, May HT, McComsey GA, McDonald D, Mendez-Figueroa H, Miele L, Mittleman MA, Mohandas S, Mouchati C, Mullington JM, Nadkarni GN, Nahin ER, Neuman RB, Newman LT, Nguyen A, Nikolich JZ, Ofotokun I, Ogbogu PU, Palatnik A, Palomares KTS, Parimon T, Parry S, Parthasarathy S, Patterson TF, Pearman A, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Porterfield JZ, Quigley JG, Quinn DK, Raissy H, Rebello CJ, Reddy UM, Reece R, Reeder HT, Rischard FP, Rosas JM, Rosen CJ, Rouphael NG, Rouse DJ, Ruff AM, Saint Jean C, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Selvaggi C, Seshadri S, Sesso HD, Shah DP, Shemesh E, Sherif ZA, Shinnick DJ, Simhan HN, Singh U, Sowles A, Subbian V, Sun J, Suthar MS, Teunis LJ, Thorp JM, Ticotsky A, Tita ATN, Tragus R, Tuttle KR, Urdaneta AE, Utz PJ, VanWagoner TM, Vasey A, Vernon SD, Vidal C, Walker T, Ward HD, Warren DE, Weeks RM, Weiner SJ, Weyer JC, Wheeler JL, Whiteheart SW, Wiley Z, Williams NJ, Wisnivesky JP, Wood JC, Yee LM, Young NM, Zisis SN, Foulkes AS. PMID: 37352211; PMCID: PMC10289397.
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6 Fields:
Translation:
HumansCellsCTClinical Trials
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Prevention, treatment and cure of HIV infection. Nat Rev Microbiol. 2023 10; 21(10):657-670.
Landovitz RJ, Scott H, Deeks SG. PMID: 37344551.
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17 Fields:
Translation:
Humans
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Association of Culturable-Virus Detection and Household Transmission of SARS-CoV-2, California and Tennessee, 2020-2022. J Infect Dis. 2023 06 15; 227(12):1343-1347.
Deyoe JE, Kelly JD, Grijalva CG, Bonenfant G, Lu S, Anglin K, Garcia-Knight M, Pineda-Ramirez J, Hagen MB, Saydah S, Abedi GR, Goldberg SA, Tassetto M, Zhang A, Donohue KC, Davidson MC, Sanchez RD, Djomaleu M, Mathur S, Shak JR, Deeks SG, Peluso MJ, Chiu CY, Zhu Y, Halasa NB, Chappell JD, Mellis A, Reed C, Andino R, Martin JN, Zhou B, Talbot HK, Midgley CM, Rolfes MA. PMID: 36705269; PMCID: PMC10266938.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. JAMA. 2023 06 13; 329(22):1934-1946.
Thaweethai T, Jolley SE, Karlson EW, Levitan EB, Levy B, McComsey GA, McCorkell L, Nadkarni GN, Parthasarathy S, Singh U, Walker TA, Selvaggi CA, Shinnick DJ, Schulte CCM, Atchley-Challenner R, Alba GA, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett IV, Bateman L, Bedi B, Bhattacharyya S, Bind MA, Blomkalns AL, Bonilla H, Brim H, Bush PA, Castro M, Chan J, Charney AW, Chen P, Chibnik LB, Chu HY, Clifton RG, Costantine MM, Cribbs SK, Davila Nieves SI, Deeks SG, Duven A, Emery IF, Erdmann N, Erlandson KM, Ernst KC, Farah-Abraham R, Farner CE, Feuerriegel EM, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander JC, Gardner EM, Geng LN, Gibson KS, Go M, Goldman JD, Grebe H, Greenway FL, Habli M, Hafner J, Han JE, Hanson KA, Heath J, Hernandez C, Hess R, Hodder SL, Hoffman MK, Hoover SE, Huang B, Hughes BL, Jagannathan P, John J, Jordan MR, Katz SD, Kaufman ES, Kelly JD, Kelly SW, Kemp MM, Kirwan JP, Klein JD, Knox KS, Krishnan JA, Kumar A, Laiyemo AO, Lambert AA, Lanca M, Lee-Iannotti JK, Logarbo BP, Longo MT, Luciano CA, Lutrick K, Maley JH, Mallett G, Marathe JG, Marconi V, Marshall GD, Martin CF, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz TD, Morse R, Mosier J, Mouchati C, Mullington J, Murphy SN, Neuman RB, Nikolich JZ, Ofotokun I, Ojemakinde E, Palatnik A, Palomares K, Parimon T, Parry S, Patterson JE, Patterson TF, Patzer RE, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Quigley JG, Reddy U, Reece R, Reeder H, Reeves WB, Reiman EM, Rischard F, Rosand J, Rouse DJ, Ruff A, Saade G, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Shepherd F, Sherif ZA, Simhan H, Singer NG, Skupski DW, Sowles A, Sparks JA, Sukhera FI, Taylor BS, Teunis L, Thomas RJ, Thorp JM, Thuluvath P, Ticotsky A, Tita AT, Tuttle KR, Urdaneta AE, Valdivieso D, VanWagoner TM, Vasey A, Verduzco-Gutierrez M, Wallace ZS, Ward HD, Warren DE, Weiner SJ, Welch S, Whiteheart SW, Wiley Z, Wisnivesky JP, Yee LM, Zisis S, Horwitz LI, Foulkes AS, RECOVER Consortium. PMID: 37278994; PMCID: PMC10214179.
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145 Fields:
Translation:
HumansCells
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Autoantigen profiling reveals a shared post-COVID signature in fully recovered and long COVID patients. JCI Insight. 2023 06 08; 8(11).
Bodansky A, Wang CY, Saxena A, Mitchell A, Kung AF, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, Kelly JD, Martin JN, Anderson MS, Deeks SG, Henrich TJ, DeRisi JL, Peluso MJ. PMID: 37288661; PMCID: PMC10393220.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Association of SARS-CoV-2 Infection and Cardiopulmonary Long COVID with Exercise Capacity and Chronotropic Incompetence among People with HIV. medRxiv. 2023 May 02.
Durstenfeld MS, Peluso MJ, Spinelli MA, Li D, Hoh R, Gandhi M, Henrich TJ, Aras MA, Long CS, Deeks SG, Hsue PY. PMID: 37205522; PMCID: PMC10187359.
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MultiSero: An Open-Source Multiplex-ELISA Platform for Measuring Antibody Responses to Infection. Pathogens. 2023 May 02; 12(5).
Byrum JR, Waltari E, Janson O, Guo SM, Folkesson J, Chhun BB, Vinden J, Ivanov IE, Forst ML, Li H, Larson AG, Blackmon L, Liu Z, Wu W, Ahyong V, Tato CM, McCutcheon KM, Hoh R, Kelly JD, Martin JN, Peluso MJ, Henrich TJ, Deeks SG, Prakash M, Greenhouse B, Mehta SB, Pak JE. PMID: 37242341; PMCID: PMC10221076.
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PubMed Mentions:
4
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SIV clearance from neonatal macaques following transient CCR5 depletion. bioRxiv. 2023 May 01.
Deere JD, Merriam D, Leggat KM, Chang WW, Méndez-Lagares G, Kieu H, Dutra J, Fontaine J, Lu W, Chin N, Chen C, Tran BC, Salinas J, Miller CN, Deeks SG, Lifson JD, Engelman K, Magnani D, Reimann K, Stevenson M, Hartigan-O'Connor DJ. PMID: 37205470; PMCID: PMC10187202.
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A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design. J Exp Med. 2023 07 03; 220(7).
Sengupta S, Zhang J, Reed MC, Yu J, Kim A, Boronina TN, Board NL, Wrabl JO, Shenderov K, Welsh RA, Yang W, Timmons AE, Hoh R, Cole RN, Deeks SG, Siliciano JD, Siliciano RF, Sadegh-Nasseri S. PMID: 37058141; PMCID: PMC10114365.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Correction: Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI). Gene Ther. 2023 Apr; 30(3-4):405.
Adair JE, Androski L, Bayigga L, Bazira D, Brandon E, Dee L, Deeks S, Draz M, Dubé K, Dybul M, Gurkan U, Harlow E, Kityo C, Louella M, Malik P, Mathews V, McKemey A, Mugerwa H, Muyanja D, Olayiwola O, Orentas RJ, Popovski A, Sheehy J, Ssali F, Nsubuga MS, Tisdale JF, Verhoeyen E, Dropulic B. PMID: 34584245; PMCID: PMC10300648.
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PubMed Mentions: Fields:
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Viral and Host Mediators of Non-Suppressible HIV-1 Viremia. medRxiv. 2023 Mar 31.
Mohammadi A, Etemad B, Zhang X, Li Y, Bedwell GJ, Sharaf R, Kittilson A, Melberg M, Wong C, Fajnzylber J, Worrall DP, Rosenthal A, Jordan H, Jilg N, Kaseke C, Giguel F, Lian X, Deo R, Gillespie E, Chishti R, Abrha S, Adams T, Siagian A, Anderson PL, Deeks SG, Lederman MM, Yawetz S, Kuritzkes DR, Lichterfeld MD, Tsibris A, Carrington M, Brumme ZL, Castillo-Mancilla JR, Engelman AN, Gaiha GD, Li JZ. PMID: 37034605; PMCID: PMC10081408.
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The Breadth of the Neutralizing Antibody Response to Original SARS-CoV-2 Infection is Linked to the Presence of Long COVID Symptoms. medRxiv. 2023 Mar 31.
Buck AM, Deitchman AN, Takahashi S, Lu S, Goldberg SA, Hoh R, Williams MC, Kerbleski M, Deveau TM, Munter SE, Lombardo J, Wrin T, Petropoulos CJ, Durstenfeld MS, Hsue PY, Kelly JD, Greenhouse B, Martin JN, Deeks SG, Peluso MJ, Henrich TJ. PMID: 37034660; PMCID: PMC10081395.
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Soluble immune checkpoints as correlates for HIV persistence and T cell function in people with HIV on antiretroviral therapy. Front Immunol. 2023; 14:1123342.
Chiu CY, Schou MD, McMahon JH, Deeks SG, Fromentin R, Chomont N, Wykes MN, Rasmussen TA, Lewin SR. PMID: 37056754; PMCID: PMC10086427.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Reduced exercise capacity, chronotropic incompetence, and early systemic inflammation in cardiopulmonary phenotype Long COVID. medRxiv. 2023 Mar 21.
Durstenfeld MS, Peluso MJ, Kaveti P, Hill C, Li D, Sander E, Swaminathan S, Arechiga VM, Lu S, Goldberg SA, Hoh R, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kelly JD, Glidden DV, Henrich TJ, Martin JN, Lee YJ, Aras MA, Long CS, Grandis DJ, Deeks SG, Hsue PY. PMID: 35677073; PMCID: PMC9176659.
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PubMed Mentions:
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Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients. medRxiv. 2023 Feb 09.
Bodansky A, Wang CY, Saxena A, Mitchell A, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, Kelly JD, Martin JN, Anderson MS, Deeks SG, Henrich TJ, DeRisi JL, Peluso MJ. PMID: 36798288; PMCID: PMC9934805.
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PubMed Mentions:
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Chronic viral coinfections differentially affect the likelihood of developing long COVID. J Clin Invest. 2023 02 01; 133(3).
Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deitchman AN, Hellmuth J, Spinelli MA, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Deeks SG, Hunt PW, Henrich TJ. PMID: 36454631; PMCID: PMC9888380.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus. Nat Microbiol. 2023 02; 8(2):260-271.
Kincer LP, Joseph SB, Gilleece MM, Hauser BM, Sizemore S, Zhou S, Di Germanio C, Zetterberg H, Fuchs D, Deeks SG, Spudich S, Gisslen M, Price RW, Swanstrom R. PMID: 36717718; PMCID: PMC10201410.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4. Front Immunol. 2023; 14:1064346.
Fisher K, Schlub TE, Boyer Z, Rasmussen TA, Rhodes A, Hoh R, Hecht FM, Deeks SG, Lewin SR, Palmer S. PMID: 36776833; PMCID: PMC9909745.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Differences in expression of tumor suppressor, innate immune, inflammasome, and potassium/gap junction channel host genes significantly predict viral reservoir size during treated HIV infection. bioRxiv. 2023 Jan 12.
Dwivedi AK, Siegel DA, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Levy CN, Roychoudhury P, Hladik F, Jerome KR, Henrich TJ, Deeks SG, Lee SA. PMID: 36712077; PMCID: PMC9882059.
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Low Prevalence of Interferon α Autoantibodies in People Experiencing Symptoms of Post-Coronavirus Disease 2019 (COVID-19) Conditions, or Long COVID. J Infect Dis. 2023 01 11; 227(2):246-250.
Peluso MJ, Mitchell A, Wang CY, Takahashi S, Hoh R, Tai V, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Wilson MR, Greenhouse B, Deeks SG, DeRisi JL, Henrich TJ. PMID: 36089700; PMCID: PMC9494362.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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HIV silencing and cell survival signatures in infected T cell reservoirs. Nature. 2023 02; 614(7947):318-325.
Clark IC, Mudvari P, Thaploo S, Smith S, Abu-Laban M, Hamouda M, Theberge M, Shah S, Ko SH, Pérez L, Bunis DG, Lee JS, Kilam D, Zakaria S, Choi S, Darko S, Henry AR, Wheeler MA, Hoh R, Butrus S, Deeks SG, Quintana FJ, Douek DC, Abate AR, Boritz EA. PMID: 36599978; PMCID: PMC9908556.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy. Cell Host Microbe. 2023 01 11; 31(1):83-96.e5.
Lian X, Seiger KW, Parsons EM, Gao C, Sun W, Gladkov GT, Roseto IC, Einkauf KB, Osborn MR, Chevalier JM, Jiang C, Blackmer J, Carrington M, Rosenberg ES, Lederman MM, McMahon DK, Bosch RJ, Jacobson JM, Gandhi RT, Peluso MJ, Chun TW, Deeks SG, Yu XG, Lichterfeld M. PMID: 36596305; PMCID: PMC9839361.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Transcriptomic Signatures of Human Immunodeficiency Virus Post-Treatment Control. J Virol. 2023 01 31; 97(1):e0125422.
Wedrychowski A, Martin HA, Li Y, Telwatte S, Kadiyala GN, Melberg M, Etemad B, Connick E, Jacobson JM, Margolis DM, Skiest D, Volberding P, Hecht F, Deeks S, Wong JK, Li JZ, Yukl SA. PMID: 36541802; PMCID: PMC9888280.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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New Assay Reveals Vast Excess of Defective over Intact HIV-1 Transcripts in Antiretroviral Therapy-Suppressed Individuals. J Virol. 2022 12 21; 96(24):e0160522.
Martin HA, Kadiyala GN, Telwatte S, Wedrychowski A, Chen TH, Moron-Lopez S, Arneson D, Hoh R, Deeks S, Wong J, Yukl SA. PMID: 36448806; PMCID: PMC9769383.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Host variation in type I interferon signaling genes (MX1), C-C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers predict viral reservoir size. AIDS. 2023 03 01; 37(3):477-488.
Siegel DA, Thanh C, Wan E, Hoh R, Hobbs K, Pan T, Gibson EA, Kroetz DL, Martin J, Hecht F, Pilcher C, Martin M, Carrington M, Pillai S, Busch MP, Stone M, Levy CN, Huang ML, Roychoudhury P, Hladik F, Jerome KR, Kiem HP, Henrich TJ, Deeks SG, Lee SA. PMID: 36695358; PMCID: PMC9894159.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Persistence of envelopes in different CD4+ T-cell subsets in antiretroviral therapy-suppressed people with HIV. AIDS. 2023 02 01; 37(2):247-257.
Gartner MJ, Tumpach C, Dantanarayana A, Stern J, Zerbato JM, Chang JJ, Angelovich TA, Anderson JL, Symons J, Deeks SG, Flynn JK, Lewin SR, Churchill MJ, Gorry PR, Roche M. PMID: 36541637; PMCID: PMC9794144.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Willingness of Racially Diverse Young Adults Living with HIV to Participate in HIV Cure Research: A Cross-Sectional Survey in the United States. AIDS Res Hum Retroviruses. 2023 08; 39(8):381-399.
Dubé K, Campbell CK, Eskaf S, Sauceda JA, Ndukwe S, Henley L, Persaud D, Deeks SG, Auerbach JD, Saberi P. PMID: 36226414; PMCID: PMC10387162.
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Translation:
Humans
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In vivo killing of primary HIV-infected cells by peripheral-injected early memory-enriched anti-HIV duoCAR T cells. JCI Insight. 2022 11 08; 7(21).
Anthony-Gonda K, Ray A, Su H, Wang Y, Xiong Y, Lee D, Block A, Chilunda V, Weiselberg J, Zemelko L, Wang YY, Kleinsorge-Block S, Reese JS, de Lima M, Ochsenbauer C, Kappes JC, Dimitrov DS, Orentas R, Deeks SG, Rutishauser RL, Berman JW, Goldstein H, Dropulic B. PMID: 36345941; PMCID: PMC9675454.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Antigen in the Blood as a Diagnostic Test for Infection and Infectious Viral Shedding. Open Forum Infect Dis. 2022 Nov; 9(11):ofac563.
Mathur S, Davidson MC, Anglin K, Lu S, Goldberg SA, Garcia-Knight M, Tassetto M, Zhang A, Romero M, Pineda-Ramirez J, Diaz-Sanchez R, Rugart P, Chen JY, Donohue K, Shak JR, Chenna A, Winslow JW, Petropoulos CJ, Yee BC, Lambert J, Glidden DV, Rutherford GW, Deeks SG, Peluso MJ, Andino R, Martin JN, Kelly JD. PMID: 36381627; PMCID: PMC9620332.
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4
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Impact of Tamoxifen on Vorinostat-Induced Human Immunodeficiency Virus Expression in Women on Antiretroviral Therapy: AIDS Clinical Trials Group A5366, The MOXIE Trial. Clin Infect Dis. 2022 10 12; 75(8):1389-1396.
Scully EP, Aga E, Tsibris A, Archin N, Starr K, Ma Q, Morse GD, Squires KE, Howell BJ, Wu G, Hosey L, Sieg SF, Ehui L, Giguel F, Coxen K, Dobrowolski C, Gandhi M, Deeks S, Chomont N, Connick E, Godfrey C, Karn J, Kuritzkes DR, Bosch RJ, Gandhi RT. PMID: 35176755; PMCID: PMC9555843.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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A common allele of HLA mediates asymptomatic SARS-CoV-2 infection. medRxiv. 2022 Oct 12.
Augusto DG, Yusufali T, Sabatino JJ, Peyser ND, Murdolo LD, Butcher X, Murray V, Pae V, Sarvadhavabhatla S, Beltran F, Gill G, Lynch K, Yun C, Maguire C, Peluso MJ, Hoh R, Henrich TJ, Deeks SG, Davidson M, Lu S, Goldberg SA, Kelly JD, Martin JN, Viera-Green CA, Spellman SR, Langton DJ, Lee S, Marcus GM, Olgin JE, Pletcher MJ, Gras S, Maiers M, Hollenbach JA. PMID: 34031661; PMCID: PMC8142661.
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Memory CD4+ T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency. Cell Rep Med. 2022 10 18; 3(10):100766.
Rasmussen TA, Zerbato JM, Rhodes A, Tumpach C, Dantanarayana A, McMahon JH, Lau JSY, Chang JJ, Gubser C, Brown W, Hoh R, Krone M, Pascoe R, Chiu CY, Bramhall M, Lee HJ, Haque A, Fromentin R, Chomont N, Milush J, Van der Sluis RM, Palmer S, Deeks SG, Cameron PU, Evans V, Lewin SR. PMID: 36198308; PMCID: PMC9589005.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Magnitude and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Household Transmission: A Longitudinal Cohort Study. Clin Infect Dis. 2022 10 03; 75(Suppl 2):S193-S204.
Kelly JD, Lu S, Anglin K, Garcia-Knight M, Pineda-Ramirez J, Goldberg SA, Tassetto M, Zhang A, Donohue K, Davidson MC, Romero M, Diaz Sanchez R, Djomaleu M, Mathur S, Chen JY, Forman CA, Servellita V, Montejano RD, Shak JR, Rutherford GW, Deeks SG, Abedi GR, Rolfes MA, Saydah S, Briggs-Hagen M, Peluso MJ, Chiu C, Midgley CM, Andino R, Martin JN. PMID: 35788827; PMCID: PMC9278251.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling. JCI Insight. 2022 Sep 22; 7(18).
Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Bishehsari F, Balk RA, Moy JN, Hoh R, Lu S, Goldman AR, Tang HY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Kelly JD, Wasse H, Martin JN, Liu Q, Keshavarzian A, Landay A, Deeks SG, Henrich TJ, Abdel-Mohsen M. PMID: 36134654; PMCID: PMC9675436.
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PubMed Mentions:
6 Fields:
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Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study. PLoS Pathog. 2022 09; 18(9):e1010802.
Garcia-Knight M, Anglin K, Tassetto M, Lu S, Zhang A, Goldberg SA, Catching A, Davidson MC, Shak JR, Romero M, Pineda-Ramirez J, Diaz-Sanchez R, Rugart P, Donohue K, Massachi J, Sans HM, Djomaleu M, Mathur S, Servellita V, McIlwain D, Gaudiliere B, Chen J, Martinez EO, Tavs JM, Bronstone G, Weiss J, Watson JT, Briggs-Hagen M, Abedi GR, Rutherford GW, Deeks SG, Chiu C, Saydah S, Peluso MJ, Midgley CM, Martin JN, Andino R, Kelly JD. PMID: 36095030; PMCID: PMC9499220.
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PubMed Mentions:
22 Fields:
Translation:
HumansCellsPHPublic Health
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CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. mBio. 2022 10 26; 13(5):e0189122.
Packard TA, Schwarzer R, Herzig E, Rao D, Luo X, Egedal JH, Hsiao F, Widera M, Hultquist JF, Grimmett ZW, Messer RJ, Krogan NJ, Deeks SG, Roan NR, Dittmer U, Hasenkrug KJ, Greene WC. PMID: 36073812; PMCID: PMC9600577.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Differences in Post-mRNA Vaccination Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunoglobulin G (IgG) Concentrations and Surrogate Virus Neutralization Test Response by Human Immunodeficiency Virus (HIV) Status and Type of Vaccine: A Matched Case-Control Observational Study. Clin Infect Dis. 2022 08 24; 75(1):e916-e919.
Spinelli MA, Peluso MJ, Lynch KL, Yun C, Glidden DV, Henrich TJ, Deeks SG, Gandhi M. PMID: 34864962; PMCID: PMC8689738.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCellsPHPublic Health
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Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling. JCI Insight. 2022 08 08; 7(15).
Giron LB, Peluso MJ, Ding J, Kenny G, Zilberstein NF, Koshy J, Hong KY, Rasmussen H, Miller GE, Bishehsari F, Balk RA, Moy JN, Hoh R, Lu S, Goldman AR, Tang HY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Kelly JD, Wasse H, Martin JN, Liu Q, Keshavarzian A, Landay A, Deeks SG, Henrich TJ, Abdel-Mohsen M. PMID: 35727635; PMCID: PMC9462470.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
Methotrexate Inhibits T Cell Proliferation but Not Inflammatory Cytokine Expression to Modulate Immunity in People Living With HIV. Front Immunol. 2022; 13:924718.
Freeman ML, Clagett BM, Moisi D, Yeh E, Morris CD, Ryu A, Rodriguez B, Stein JH, Deeks SG, Currier JS, Hsue PY, Anthony DD, Calabrese LH, Ribaudo HJ, Lederman MM. PMID: 35967371; PMCID: PMC9374564.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques. Front Immunol. 2022; 13:945706.
Valentin A, Bergamaschi C, Rosati M, Angel M, Burns R, Agarwal M, Gergen J, Petsch B, Oostvogels L, Loeliger E, Chew KW, Deeks SG, Mullins JI, Pavlakis GN, Felber BK. PMID: 35935984; PMCID: PMC9355630.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Impact of Pre-Existing Chronic Viral Infection and Reactivation on the Development of Long COVID. medRxiv. 2022 Jul 22.
Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Beck-Engeser G, Chan F, Lu S, Goldberg SA, Hoh R, Tai V, Torres L, Iyer NS, Deswal M, Ngo LH, Buitrago M, Rodriguez A, Chen JY, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Deitchman AN, Hellmuth J, Spinelli MA, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Deeks SG, Hunt PW, Henrich TJ. PMID: 35898346; PMCID: PMC9327632.
View in:
PubMed Mentions:
-
Postacute sequelae and adaptive immune responses in people with HIV recovering from SARS-COV-2 infection. AIDS. 2022 10 01; 36(12):F7-F16.
Peluso MJ, Spinelli MA, Deveau TM, Forman CA, Munter SE, Mathur S, Tang AF, Lu S, Goldberg SA, Arreguin MI, Hoh R, Tai V, Chen JY, Martinez EO, Yee BC, Chenna A, Winslow JW, Petropoulos CJ, Sette A, Weiskopf D, Kumar N, Lynch KL, Hunt PW, Durstenfeld MS, Hsue PY, Kelly JD, Martin JN, Glidden DV, Gandhi M, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 35866847; PMCID: PMC9444925.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
-
LOXL-2 and TNC-C are markers of liver fibrogenesis in HCV/HIV-, HIV- and HCV-infected patients. Biomark Med. 2022 08; 16(11):839-846.
Altinbas A, Holmes JA, Salloum S, Lidofsky A, Alatrakchi N, Somsouk M, Hunt P, Deeks S, Chew KW, Lauer G, Kruger A, Lin W, Chung RT. PMID: 35786977; PMCID: PMC9437769.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
21
-
View in:
PubMed Mentions:
-
Plasma Markers of Neurologic Injury and Inflammation in People With Self-Reported Neurologic Postacute Sequelae of SARS-CoV-2 Infection. Neurol Neuroimmunol Neuroinflamm. 2022 09; 9(5).
Peluso MJ, Sans HM, Forman CA, Nylander AN, Ho HE, Lu S, Goldberg SA, Hoh R, Tai V, Munter SE, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Martin JN, Kelly JD, Durstenfeld MS, Hsue PY, Hunt PW, Greene M, Chow FC, Hellmuth J, Henrich TJ, Glidden DV, Deeks SG. PMID: 35701186; PMCID: PMC9210548.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
Lack of Antinuclear Antibodies in Convalescent Coronavirus Disease 2019 Patients With Persistent Symptoms. Clin Infect Dis. 2022 06 10; 74(11):2083-2084.
Peluso MJ, Thomas IJ, Munter SE, Deeks SG, Henrich TJ. PMID: 34617982; PMCID: PMC9187313.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Predictive value of CD8+ T cell and CD4/CD8 ratio at two years of successful ART in the risk of AIDS and non-AIDS events. EBioMedicine. 2022 Jun; 80:104072.
Serrano-Villar S, Wu K, Hunt PW, Lok JJ, Ron R, Sainz T, Moreno S, Deeks SG, Bosch RJ. PMID: 35644125; PMCID: PMC9156990.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Role of antibodies, inflammatory markers, and echocardiographic findings in postacute cardiopulmonary symptoms after SARS-CoV-2 infection. JCI Insight. 2022 05 23; 7(10).
Durstenfeld MS, Peluso MJ, Kelly JD, Win S, Swaminathan S, Li D, Arechiga VM, Zepeda V, Sun K, Shao S, Hill C, Arreguin MI, Lu S, Hoh R, Tai V, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Kornak J, Henrich TJ, Martin JN, Deeks SG, Hsue PY. PMID: 35389890; PMCID: PMC9220849.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Cell-Associated Human Immunodeficiency Virus (HIV) Ribonucleic Acid Has a Circadian Cycle in Males With HIV on Antiretroviral Therapy. J Infect Dis. 2022 05 16; 225(10):1721-1730.
Stern J, Solomon A, Dantanarayana A, Pascoe R, Reynaldi A, Davenport MP, Milush J, Deeks SG, Hartogensis W, Hecht FM, Cockerham L, Roche M, Lewin SR. PMID: 34655216; PMCID: PMC9633724.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Gut-derived bacterial toxins impair memory CD4+ T cell mitochondrial function in HIV-1 infection. J Clin Invest. 2022 05 02; 132(9).
Ferrari B, Da Silva AC, Liu KH, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive C, Pacheco Sanchez G, Retuerto M, Sharma AA, Ghneim K, Noel-Romas L, Rodriguez B, Ghannoum MA, Hunt PP, Deeks SG, Burgener AD, Jones DP, Dobre MA, Marconi VC, Sekaly RP, Younes SA. PMID: 35316209; PMCID: PMC9057623.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Variation in blood microbial lipopolysaccharide (LPS) contributes to immune reconstitution in response to suppressive antiretroviral therapy in HIV. EBioMedicine. 2022 06; 80:104037.
Luo Z, Health SL, Li M, Yang H, Wu Y, Collins M, Deeks SG, Martin JN, Scott A, Jiang W. PMID: 35500539; PMCID: PMC9065923.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Participant Perspectives and Experiences Following an Intensively Monitored Antiretroviral Pause in the United States: Results from the AIDS Clinical Trials Group A5345 Biomarker Study. AIDS Res Hum Retroviruses. 2022 06; 38(6):510-517.
Dubé K, Eskaf S, Barr L, Palm D, Hogg E, Simoni JM, Sugarman J, Brown B, Sauceda JA, Henley L, Deeks S, Fox L, Gandhi RT, Smith D, Li JZ. PMID: 35323030; PMCID: PMC9225827.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Ethical and practical considerations for cell and gene therapy toward an HIV cure: findings from a qualitative in-depth interview study in the United States. BMC Med Ethics. 2022 04 09; 23(1):39.
Dubé K, Kanazawa J, Patel H, Louella M, Sylla L, Sheehy J, Dee L, Taylor J, Adair J, Anthony-Gonda K, Dropulic B, Sauceda JA, Peluso MJ, Deeks SG, Simoni J. PMID: 35397551; PMCID: PMC8994300.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection-study protocol for a two-stage randomised phase II trial. Trials. 2022 Apr 05; 23(1):263.
Lee MJ, Collins S, Babalis D, Johnson N, Falaschetti E, Prevost AT, Ashraf A, Jacob M, Cole T, Hurley L, Pace M, Ogbe A, Khan M, Zacharopoulou P, Brown H, Sutherland E, Box H, Fox J, Deeks S, Horowitz J, Nussenzweig MC, Caskey M, Frater J, Fidler S. PMID: 35382844; PMCID: PMC8981886.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsCTClinical Trials
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The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells. J Clin Invest. 2022 04 01; 132(7).
Duette G, Hiener B, Morgan H, Mazur FG, Mathivanan V, Horsburgh BA, Fisher K, Tong O, Lee E, Ahn H, Shaik A, Fromentin R, Hoh R, Bacchus-Souffan C, Nasr N, Cunningham AL, Hunt PW, Chomont N, Turville SG, Deeks SG, Kelleher AD, Schlub TE, Palmer S. PMID: 35133986; PMCID: PMC8970682.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Cellular Activation, Differentiation, and Proliferation Influence the Dynamics of Genetically Intact Proviruses Over Time. J Infect Dis. 2022 04 01; 225(7):1168-1178.
Horsburgh BA, Hiener B, Fisher K, Lee E, Morgan H, Eden JS, von Stockenstrom S, Odevall L, Milush JM, Hoh R, Fromentin R, Chomont N, Hecht FM, Schlub TE, Deeks SG, Palmer S. PMID: 34037766; PMCID: PMC8974828.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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SARS-CoV-2 and Mitochondrial Proteins in Neural-Derived Exosomes of COVID-19. Ann Neurol. 2022 06; 91(6):772-781.
Peluso MJ, Deeks SG, Mustapic M, Kapogiannis D, Henrich TJ, Lu S, Goldberg SA, Hoh R, Chen JY, Martinez EO, Kelly JD, Martin JN, Goetzl EJ. PMID: 35285072; PMCID: PMC9082480.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Plasma-Derived HIV-1 Virions Contain Considerable Levels of Defective Genomes. J Virol. 2022 03 23; 96(6):e0201121.
Fisher K, Wang XQ, Lee A, Morcilla V, de Vries A, Lee E, Eden JS, Deeks SG, Kelleher AD, Palmer S. PMID: 35201897; PMCID: PMC8941922.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody. Nat Commun. 2022 03 09; 13(1):1219.
Beckford-Vera DR, Flavell RR, Seo Y, Martinez-Ortiz E, Aslam M, Thanh C, Fehrman E, Pardons M, Kumar S, Deitchman AN, Ravanfar V, Schulte B, Wu IK, Pan T, Reeves JD, Nixon CC, Iyer NS, Torres L, Munter SE, Hyunh T, Petropoulos CJ, Hoh R, Franc BL, Gama L, Koup RA, Mascola JR, Chomont N, Deeks SG, VanBrocklin HF, Henrich TJ. PMID: 35264559; PMCID: PMC8907355.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCellsCTClinical Trials
-
Time to Viral Rebound After Interruption of Modern Antiretroviral Therapies. Clin Infect Dis. 2022 03 09; 74(5):865-870.
Li JZ, Aga E, Bosch RJ, Pilkinton M, Kroon E, MacLaren L, Keefer M, Fox L, Barr L, Acosta E, Ananworanich J, Coombs R, Mellors JW, Landay AL, Macatangay B, Deeks S, Gandhi RT, Smith DM. PMID: 34117753; PMCID: PMC8906742.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Early clues regarding the pathogenesis of long-COVID. Trends Immunol. 2022 04; 43(4):268-270.
Peluso MJ, Deeks SG. PMID: 35272932; PMCID: PMC8901423.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health. JCI Insight. 2022 03 08; 7(5).
Swainson LA, Sharma AA, Ghneim K, Ribeiro SP, Wilkinson P, Dunham RM, Albright RG, Wong S, Estes JD, Piatak M, Deeks SG, Hunt PW, Sekaly RP, McCune JM. PMID: 35104248; PMCID: PMC8983135.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
SARS-CoV-2 Booster Vaccination for Participants in "HIV Cure"-Related Clinical Trials. J Acquir Immune Defic Syndr. 2022 03 01; 89(3):e30.
Peluso MJ, Williams MC, Campbell DM, Dee L, Taylor J, Ngo LH, Hoh R, Dubé K, Sauceda JA, Deeks SG. PMID: 35147584; PMCID: PMC8851852.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Findings From Mayo Clinic's Post-COVID Clinic: PASC Phenotypes Vary by Sex and Degree of IL-6 Elevation. Mayo Clin Proc. 2022 03; 97(3):430-432.
Durstenfeld MS, Hsue PY, Peluso MJ, Deeks SG. PMID: 35246280; PMCID: PMC8886352.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses. Nat Immunol. 2022 03; 23(3):360-370.
Tomalka JA, Suthar MS, Deeks SG, Sekaly RP. PMID: 35210622.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCellsPHPublic Health
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Mitigation strategies to safely conduct HIV treatment research in the context of COVID-19. J Int AIDS Soc. 2022 02; 25(2):e25882.
Henderson M, Fidler S, Mothe B, Grinsztejn B, Haire B, Collins S, Lau JSY, Luba M, Sanne I, Tatoud R, Deeks S, Lewin SR. PMID: 35138683; PMCID: PMC8826545.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
-
Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals. Front Immunol. 2022; 13:803417.
George AF, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, Shin MG, Lee MJ, Blish CA, Deeks SG, Greene WC, Lee SA, Roan NR. PMID: 35154118; PMCID: PMC8829545.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy. Sci Transl Med. 2022 01 26; 14(629):eabl3836.
Uldrick TS, Adams SV, Fromentin R, Roche M, Fling SP, Gonçalves PH, Lurain K, Ramaswami R, Wang CJ, Gorelick RJ, Welker JL, O'Donoghue L, Choudhary H, Lifson JD, Rasmussen TA, Rhodes A, Tumpach C, Yarchoan R, Maldarelli F, Cheever MA, Sékaly R, Chomont N, Deeks SG, Lewin SR. PMID: 35080914; PMCID: PMC9014398.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
-
Risk factors and abnormal cerebrospinal fluid associate with cognitive symptoms after mild COVID-19. Ann Clin Transl Neurol. 2022 02; 9(2):221-226.
Apple AC, Oddi A, Peluso MJ, Asken BM, Henrich TJ, Kelly JD, Pleasure SJ, Deeks SG, Allen IE, Martin JN, Ndhlovu LC, Miller BL, Stephens ML, Hellmuth J. PMID: 35043593; PMCID: PMC8862406.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults With Human Immunodeficiency Virus. Clin Infect Dis. 2022 01 07; 74(1):95-104.
Marconi VC, Moser C, Gavegnano C, Deeks SG, Lederman MM, Overton ET, Tsibris A, Hunt PW, Kantor A, Sekaly RP, Tressler R, Flexner C, Hurwitz SJ, Moisi D, Clagett B, Hardin WR, Del Rio C, Schinazi RF, Lennox JJ. PMID: 33693561; PMCID: PMC8752257.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement. Open Forum Infect Dis. 2022 Feb; 9(2):ofab640.
Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger MA, Assenzio MT, Yuan Y, Krone MR, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Scheffler AW, Hsue PY, Henrich TJ, Deeks SG, Martin JN. PMID: 35106317; PMCID: PMC8755302.
View in:
PubMed Mentions:
40
-
Characterizing the COVID-19 Illness Experience to Inform the Study of Post-acute Sequelae and Recovery. Int J Behav Med. 2022 Oct; 29(5):610-623.
Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA. PMID: 34918211; PMCID: PMC8675303.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers. Sci Transl Med. 2021 12 15; 13(624):eabl4097.
Lian X, Gao C, Sun X, Jiang C, Einkauf KB, Seiger KW, Chevalier JM, Yuki Y, Martin M, Hoh R, Peluso MJ, Carrington M, Ruiz-Mateos E, Deeks SG, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. PMID: 34910552; PMCID: PMC9202005.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021. Nat Med. 2021 12; 27(12):2085-2098.
Deeks SG, Archin N, Cannon P, Collins S, Jones RB, de Jong MAWP, Lambotte O, Lamplough R, Ndung'u T, Sugarman J, Tiemessen CT, Vandekerckhove L, Lewin SR, International AIDS Society (IAS) Global Scientific Strategy working group. PMID: 34848888.
View in:
PubMed Mentions:
99 Fields:
Translation:
Humans
-
Markers of Immune Activation and Inflammation in Individuals With Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection. J Infect Dis. 2021 12 01; 224(11):1839-1848.
Peluso MJ, Lu S, Tang AF, Durstenfeld MS, Ho HE, Goldberg SA, Forman CA, Munter SE, Hoh R, Tai V, Chenna A, Yee BC, Winslow JW, Petropoulos CJ, Greenhouse B, Hunt PW, Hsue PY, Martin JN, Daniel Kelly J, Glidden DV, Deeks SG, Henrich TJ. PMID: 34677601; PMCID: PMC8643408.
View in:
PubMed Mentions:
104 Fields:
Translation:
Humans
-
Identification and Characterization of Antigen-Specific CD8+ T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing. J Immunol. 2021 12 15; 207(12):2913-2921.
Abdulhaqq S, Ventura AB, Reed JS, Bashirova AA, Bateman KB, McDonald E, Wu HL, Greene JM, Schell JB, Morrow D, Wisskirchen K, Martin JN, Deeks SG, Carrington M, Protzer U, Früh K, Hansen SG, Picker LJ, Sacha JB, Bimber BN. PMID: 34810222; PMCID: PMC9124229.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response. J Infect Dis. 2021 11 16; 224(9):1593-1598.
Wu G, Zuck P, Goh SL, Milush JM, Vohra P, Wong JK, Somsouk M, Yukl SA, Shacklett BL, Chomont N, Haase AT, Hatano H, Schacker TW, Deeks SG, Hazuda DJ, Hunt PW, Howell BJ. PMID: 33693750; PMCID: PMC8599810.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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A High Percentage of People With Human Immunodeficiency Virus (HIV) on Antiretroviral Therapy Experience Detectable Low-Level Plasma HIV-1 RNA Following Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2021 11 02; 73(9):e2845-e2846.
Peluso MJ, Bakkour S, Busch MP, Deeks SG, Henrich TJ. PMID: 33211091; PMCID: PMC7717237.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Effect of HIV-1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction. J Am Heart Assoc. 2021 11 16; 10(22):e021397.
Thakkar AB, Ma Y, Dela Cruz M, Wu Y, Arechiga V, Swaminathan S, Ganz P, Wu AHB, Scherzer R, Deeks S, Hsue PY. PMID: 34726064; PMCID: PMC8751943.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Frequency of post treatment control varies by antiretroviral therapy restart and viral load criteria. AIDS. 2021 11 01; 35(13):2225-2227.
Fajnzylber J, Sharaf R, Hutchinson JN, Aga E, Bosch RJ, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest DJ, Margolis D, Sneller MC, Little SJ, Gulick RM, Mellors JW, Gandhi RT, Schooley RT, Henry K, Tebas P, Deeks S, Chun TW, Collier AC, Hecht FM, Li JZ, CHAMP study team. PMID: 34127579; PMCID: PMC8490281.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Considerations for designing and implementing combination HIV cure trials: findings from a qualitative in-depth interview study in the United States. AIDS Res Ther. 2021 10 18; 18(1):75.
Dubé K, Kanazawa J, Dee L, Taylor J, Sauceda JA, Gianella S, Smith D, Deeks SG, Peluso MJ. PMID: 34663375; PMCID: PMC8522863.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size. J Infect Dis. 2021 10 13; 224(7):1209-1218.
Stone M, Rosenbloom DIS, Bacchetti P, Deng X, Dimapasoc M, Keating S, Bakkour S, Richman DD, Mellors JW, Deeks SG, Lai J, Beg S, Siliciano JD, Pagliuzza A, Chomont N, Lackman-Smith C, Ptak RG, Busch MP. PMID: 32147687; PMCID: PMC8514180.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Impact of Anti-PD-1 and Anti-CTLA-4 on the Human Immunodeficiency Virus (HIV) Reservoir in People Living With HIV With Cancer on Antiretroviral Therapy: The AIDS Malignancy Consortium 095 Study. Clin Infect Dis. 2021 10 05; 73(7):e1973-e1981.
Rasmussen TA, Rajdev L, Rhodes A, Dantanarayana A, Tennakoon S, Chea S, Spelman T, Lensing S, Rutishauser R, Bakkour S, Busch M, Siliciano JD, Siliciano RF, Einstein MH, Dittmer DP, Chiao E, Deeks SG, Durand C, Lewin SR. PMID: 33677480; PMCID: PMC8492152.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCellsCTClinical Trials
-
HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives. mBio. 2021 10 26; 12(5):e0244721.
Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S. PMID: 34544282; PMCID: PMC8546577.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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SARS-CoV-2 serology across scales: a framework for unbiased seroprevalence estimation incorporating antibody kinetics and epidemic recency. medRxiv. 2021 Sep 14.
Takahashi S, Peluso MJ, Hakim J, Turcios K, Janson O, Routledge I, Busch MP, Hoh R, Tai V, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Greenhouse B, Rodríguez-Barraquer I. PMID: 34545373; PMCID: PMC8452112.
View in:
PubMed Mentions:
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Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI). Gene Ther. 2023 04; 30(3-4):216-221.
Adair JE, Androski L, Bayigga L, Bazira D, Brandon E, Dee L, Deeks S, Draz M, Dubé K, Dybul M, Gurkan U, Harlow E, Kityo C, Louella M, Malik P, Mathews V, McKemey A, Mugerwa H, Muyanja D, Olayiwola O, Orentas RJ, Popovski A, Sheehy J, Ssali F, Nsubuga MS, Tisdale JF, Verhoeyen E, Dropulic B. PMID: 34493840; PMCID: PMC10113145.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia. Immunity. 2021 10 12; 54(10):2372-2384.e7.
Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, Lichterfeld M, Yu XG, Gaiha GD, Allen TM, Walker BD. PMID: 34496223; PMCID: PMC8516715.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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HIV Antibody Profiles in HIV Controllers and Persons With Treatment-Induced Viral Suppression. Front Immunol. 2021; 12:740395.
Kammers K, Chen A, Monaco DR, Hudelson SE, Grant-McAuley W, Moore RD, Alter G, Deeks SG, Morrison CS, Eller LA, Blankson JN, Laeyendecker O, Ruczinski I, Eshleman SH, Larman HB. PMID: 34512672; PMCID: PMC8428532.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms. Cell Rep. 2021 08 10; 36(6):109518.
Peluso MJ, Deitchman AN, Torres L, Iyer NS, Munter SE, Nixon CC, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman EA, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. PMID: 34358460; PMCID: PMC8342976.
View in:
PubMed Mentions:
100 Fields:
Translation:
HumansCells
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SARS-CoV-2 Vaccination in the Context of Ongoing HIV Cure-Related Research Studies. J Acquir Immune Defic Syndr. 2021 08 01; 87(4):e232-e233.
Peluso MJ, Dee L, Taylor J, Campbell DM, Ehm A, Agosto-Rosario M, Shao S, Williams MC, Hoh R, Rutishauser RL, Deeks SG, Sauceda JA, Dubé K. PMID: 33852502; PMCID: PMC8217209.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansPHPublic Health
-
SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay. Sci Adv. 2021 Jul; 7(31).
Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Donatelli J, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petropoulos CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. PMID: 34330709; PMCID: PMC8324059.
View in:
PubMed Mentions:
86 Fields:
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Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. Open Forum Infect Dis. 2021 Aug; 8(8):ofab393.
Peluso MJ, Munter SE, Lynch KL, Yun C, Torres L, Iyer NS, Donatelli J, Ryan L, Deitchman AN, Deeks SG, Rutishauser RL, Henrich TJ. PMID: 34395717; PMCID: PMC8344490.
View in:
PubMed Mentions:
2
-
The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy. Sci Transl Med. 2021 06 23; 13(599).
SenGupta D, Brinson C, DeJesus E, Mills A, Shalit P, Guo S, Cai Y, Wallin JJ, Zhang L, Humeniuk R, Begley R, Geleziunas R, Mellors J, Wrin T, Jones N, Milush J, Ferre AL, Shacklett BL, Laird GM, Moldt B, Vendrame E, Brainard DM, Ramgopal M, Deeks SG. PMID: 34162752.
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Abnormal Levels of Some Biomarkers of Immune Activation Despite Very Early Treatment of Human Immunodeficiency Virus. J Infect Dis. 2021 05 20; 223(9):1621-1630.
Schnittman SR, Deitchman AN, Beck-Engeser G, Ahn H, York VA, Hartig H, Hecht FM, Martin JN, Deeks SG, Aweeka FT, Hunt PW. PMID: 32915986; PMCID: PMC8136975.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Operationalizing Human Immunodeficiency Virus Cure-related Trials with Analytic Treatment Interruptions During the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pandemic: A Collaborative Approach. Clin Infect Dis. 2021 05 18; 72(10):1843-1849.
Peluso MJ, Dee L, Shao S, Taylor J, Campbell D, Collins S, Gandhi M, Johnston R, Deeks SG, Sauceda JA, Dubé K. PMID: 32841311; PMCID: PMC7499539.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCellsPHPublic Health
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multiSero: open multiplex-ELISA platform for analyzing antibody responses to SARS-CoV-2 infection. medRxiv. 2021 May 11.
Byrum JR, Waltari E, Janson O, Guo SM, Folkesson J, Chhun BB, Vinden J, Ivanov IE, Forst ML, Li H, Larson AG, Wu W, Tato CM, McCutcheon KM, Peluso MJ, Henrich TJ, Deeks SG, Prakash M, Greenhouse B, Pak JE, Mehta SB. PMID: 34013298; PMCID: PMC8132273.
View in:
PubMed Mentions:
1
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Brief Report: Lower Socioeconomic Status Associates With Greater Systemic and Arterial Inflammation in HIV. J Acquir Immune Defic Syndr. 2021 05 01; 87(1):706-710.
Zhang L, Abohashem S, Osborne MT, Naddaf N, Park R, Moore K, Patrich T, Deeks SG, Hsue PY, Tawakol AA. PMID: 33492022; PMCID: PMC8026700.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Short Communication: A Pilot Study of the Effects of Losartan Versus Placebo on Pneumoproteins in HIV: A Secondary Analysis of a Randomized Double Blind Study. AIDS Res Hum Retroviruses. 2022 02; 38(2):127-130.
MacDonald DM, Collins G, Wendt CH, Wolfson J, Tracy RP, Rhame F, Deeks S, Rizza SA, Temesgen Z, Morse C, Liappis AP, Sereti I, Baker JV, Kunisaki KM. PMID: 33749317; PMCID: PMC8861910.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
CpG Methylation Profiles of HIV-1 Pro-Viral DNA in Individuals on ART. Viruses. 2021 04 29; 13(5).
Boltz VF, Ceriani C, Rausch JW, Shao W, Bale MJ, Keele BF, Hoh R, Milush JM, Deeks SG, Maldarelli F, Kearney MF, Coffin JM. PMID: 33946976; PMCID: PMC8146454.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo. Cell Rep. 2021 04 27; 35(4):109038.
Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR. PMID: 33910003; PMCID: PMC8202093.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir. Cell Rep Med. 2021 04 20; 2(4):100243.
Levy CN, Hughes SM, Roychoudhury P, Reeves DB, Amstuz C, Zhu H, Huang ML, Wei Y, Bull ME, Cassidy NAJ, McClure J, Frenkel LM, Stone M, Bakkour S, Wonderlich ER, Busch MP, Deeks SG, Schiffer JT, Coombs RW, Lehman DA, Jerome KR, Hladik F. PMID: 33948574; PMCID: PMC8080125.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Characterizing the COVID-19 illness experience to inform the study of post-acute sequelae and recovery: a qualitative study. medRxiv. 2021 Mar 24.
Santiago-Rodriguez EI, Maiorana A, Peluso MJ, Hoh R, Tai V, Fehrman EA, Hernandez Y, Torres L, Spinelli MA, Gandhi M, Kelly JD, Martin JN, Henrich TJ, Deeks SG, Sauceda JA. PMID: 33758881; PMCID: PMC7987040.
View in:
PubMed Mentions:
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Losartan to reduce inflammation and fibrosis endpoints in HIV disease. AIDS. 2021 03 15; 35(4):575-583.
Baker JV, Wolfson J, Collins G, Morse C, Rhame F, Liappis AP, Rizza S, Temesgen Z, Mystakelis H, Deeks S, Neaton J, Schacker T, Sereti I, Tracy RP. PMID: 33252490; PMCID: PMC8062089.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19. medRxiv. 2021 Mar 12.
Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger M, Assenzio M, Yuan Y, Krone M, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Hsue PY, Henrich TJ, Deeks SG, Martin JN. PMID: 33758895; PMCID: PMC7987054.
View in:
PubMed Mentions:
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SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay. medRxiv. 2021 Mar 05.
Peluso MJ, Takahashi S, Hakim J, Kelly JD, Torres L, Iyer NS, Turcios K, Janson O, Munter SE, Thanh C, Nixon CC, Hoh R, Tai V, Fehrman EA, Hernandez Y, Spinelli MA, Gandhi M, Palafox MA, Vallari A, Rodgers MA, Prostko J, Hackett J, Trinh L, Wrin T, Petroplolous CJ, Chiu CY, Norris PJ, DiGermanio C, Stone M, Busch MP, Elledge SK, Zhou XX, Wells JA, Shu A, Kurtz TW, Pak JE, Wu W, Burbelo PD, Cohen JI, Rutishauser RL, Martin JN, Deeks SG, Henrich TJ, Rodriguez-Barraquer I, Greenhouse B. PMID: 33688675; PMCID: PMC7941652.
View in:
PubMed Mentions:
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Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19. medRxiv. 2021 Mar 01.
Peluso MJ, Deitchman AN, Torres L, Iyer NS, Nixon CC, Munter SE, Donatelli J, Thanh C, Takahashi S, Hakim J, Turcios K, Janson O, Hoh R, Tai V, Hernandez Y, Fehrman E, Spinelli MA, Gandhi M, Trinh L, Wrin T, Petropoulos CJ, Aweeka FT, Rodriguez-Barraquer I, Kelly JD, Martin JN, Deeks SG, Greenhouse B, Rutishauser RL, Henrich TJ. PMID: 33688685; PMCID: PMC7941662.
View in:
PubMed Mentions:
1
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Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency. EBioMedicine. 2021 Mar; 65:103241.
Zerbato JM, Khoury G, Zhao W, Gartner MJ, Pascoe RD, Rhodes A, Dantanarayana A, Gooey M, Anderson J, Bacchetti P, Deeks SG, McMahon J, Roche M, Rasmussen TA, Purcell DF, Lewin SR. PMID: 33647768; PMCID: PMC7920823.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Participant Perspectives and Experiences Entering an Intensively Monitored Antiretroviral Pause: Results from the AIDS Clinical Trials Group A5345 Biomarker Study. AIDS Res Hum Retroviruses. 2021 06; 37(6):489-501.
Diepstra KL, Barr L, Palm D, Hogg E, Mollan KR, Henley L, Stover AM, Simoni JM, Sugarman J, Brown B, Sauceda JA, Deeks S, Fox L, Gandhi RT, Smith D, Li JZ, Dubé K. PMID: 33472545; PMCID: PMC8213012.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations. Cells. 2021 02 13; 10(2).
Sun B, Tang N, Peluso MJ, Iyer NS, Torres L, Donatelli JL, Munter SE, Nixon CC, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Kelly JD, Martin JN, Deeks SG, Henrich TJ, Pulliam L. PMID: 33668514; PMCID: PMC7918597.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCells
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TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. JCI Insight. 2021 02 08; 6(3).
Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin C, Matus-Nicodemos R, Hoh R, Krone M, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek DC, Brenchley JM, Sékaly RP, Pillai SK, Marson A, Deeks SG, McCune JM, Hunt PW. PMID: 33351785; PMCID: PMC7934879.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo. J Virol. 2021 03 25; 95(8).
Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. PMID: 33536176; PMCID: PMC8103695.
View in:
PubMed Mentions:
10 Fields:
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Persistent COVID-19-associated neurocognitive symptoms in non-hospitalized patients. J Neurovirol. 2021 02; 27(1):191-195.
Hellmuth J, Barnett TA, Asken BM, Kelly JD, Torres L, Stephens ML, Greenhouse B, Martin JN, Chow FC, Deeks SG, Greene M, Miller BL, Annan W, Henrich TJ, Peluso MJ. PMID: 33528824; PMCID: PMC7852463.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansCells
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Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo. J Clin Invest. 2021 02 01; 131(3).
Simonetti FR, Zhang H, Soroosh GP, Duan J, Rhodehouse K, Hill AL, Beg SA, McCormick K, Raymond HE, Nobles CL, Everett JK, Kwon KJ, White JA, Lai J, Margolick JB, Hoh R, Deeks SG, Bushman FD, Siliciano JD, Siliciano RF. PMID: 33301425; PMCID: PMC7843227.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansCells
-
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19. J Leukoc Biol. 2021 07; 110(1):21-26.
Corley MJ, Pang APS, Dody K, Mudd PA, Patterson BK, Seethamraju H, Bram Y, Peluso MJ, Torres L, Iyer NS, Premeaux TA, Yeung ST, Chandar V, Borczuk A, Schwartz RE, Henrich TJ, Deeks SG, Sacha JB, Ndhlovu LC. PMID: 33464637; PMCID: PMC8013321.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART. PLoS Pathog. 2021 01; 17(1):e1009214.
Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, Schiffer JT, Lewin SR, Hellerstein MK, McCune JM, Hunt PW. PMID: 33465157; PMCID: PMC7846027.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
NIH Workshop on HIV-Associated Comorbidities, Coinfections, and Complications: Summary and Recommendation for Future Research. J Acquir Immune Defic Syndr. 2021 01 01; 86(1):11-18.
Pahwa S, Deeks S, Zou S, Tomitch N, Miller-Novak L, Caler E, Justice A, Sacktor N, Gabuzda D, Hunt PW, Brown T, Kurth A, Baral S, Mugavero M, Mayer KH, Mendenhall E, Detels R, Mutabazi V. PMID: 33306561; PMCID: PMC7982002.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Accumulation of HIV-1 Drug Resistance Mutations and Methamphetamine Use. Curr HIV Res. 2021; 19(6):497-503.
Truong HM, Fatch R, Deeks SG, Krone M, Martin JN, Hunt PW, Lum PJ. PMID: 34176462; PMCID: PMC10659984.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells. J Virol. 2020 12 22; 95(2).
Yukl SA, Khan S, Chen TH, Trapecar M, Wu F, Xie G, Telwatte S, Fulop D, Pico AR, Laird GM, Ritter KD, Jones NG, Lu CM, Siliciano RF, Roan NR, Milush JM, Somsouk M, Deeks SG, Hunt PW, Sanjabi S. PMID: 33115867; PMCID: PMC7944458.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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HIV cure research in the time of COVID-19 - Antiretroviral therapy treatment interruption trials: A discussion paper. J Virus Erad. 2021 Mar; 7(1):100025.
Fidler S, Lewin S, Deeks S, Sogaard OS, Vanderkerckhove L, Collins S, Kelly D, Singh J, Caskey M, Frater J. PMID: 33312681; PMCID: PMC7719279.
View in:
PubMed Mentions:
5
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The case for an HIV cure and how to get there. Lancet HIV. 2021 01; 8(1):e51-e58.
Dybul M, Attoye T, Baptiste S, Cherutich P, Dabis F, Deeks SG, Dieffenbach C, Doehle B, Goodenow MM, Jiang A, Kemps D, Lewin SR, Lumpkin MM, Mathae L, McCune JM, Ndung'u T, Nsubuga M, Peay HL, Pottage J, Warren M, Sikazwe I, Sunnylands 2019 Working Group. PMID: 33271124; PMCID: PMC7773626.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
Multi-stakeholder consensus on a target product profile for an HIV cure. Lancet HIV. 2021 01; 8(1):e42-e50.
Lewin SR, Attoye T, Bansbach C, Doehle B, Dubé K, Dybul M, SenGupta D, Jiang A, Johnston R, Lamplough R, McCune JM, Nabel GJ, Ndung'u T, Pottage J, Ripin D, Rooney JF, Sikazwe I, Nsubuga M, Warren M, Deeks SG, Sunnylands 2019 Working Group. PMID: 33271125; PMCID: PMC7773628.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCellsPHPublic Health
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Replicate Aptima Assay for Quantifying Residual Plasma Viremia in Individuals on Antiretroviral Therapy. J Clin Microbiol. 2020 11 18; 58(12).
Bakkour S, Deng X, Bacchetti P, Grebe E, Montalvo L, Worlock A, Stone M, Deeks SG, Richman DD, Busch MP. PMID: 32967900; PMCID: PMC7685884.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents. AIDS. 2020 11 15; 34(14):2013-2024.
Telwatte S, Kim P, Chen TH, Milush JM, Somsouk M, Deeks SG, Hunt PW, Wong JK, Yukl SA. PMID: 32910065; PMCID: PMC7990078.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Maintenance of Viral Suppression in Human Immunodeficiency Virus Controllers Despite Waning T-Cell Responses During Antiretroviral Therapy. J Infect Dis. 2020 11 09; 222(11):1837-1842.
Jilg N, Garcia-Broncano P, Peluso M, Segal FP, Bosch RJ, Roberts-Toler C, Chen SMY, Van Dam CN, Keefer MC, Kuritzkes DR, Landay AL, Deeks S, Yu XG, Sax PE, Li JZ, AIDS Clinical Trials Group A5308 Study Team. PMID: 32496516; PMCID: PMC7896274.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Universal Polymerase Chain Reaction and Antibody Testing Demonstrate Little to No Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in a Rural Community. Open Forum Infect Dis. 2021 Jan; 8(1):ofaa531.
Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett J, Chiu C, Havlir D, Greenhouse B. PMID: 34109255; PMCID: PMC7665736.
View in:
PubMed Mentions:
8
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HLA tapasin independence: broader peptide repertoire and HIV control. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28232-28238.
Bashirova AA, Viard M, Naranbhai V, Grifoni A, Garcia-Beltran W, Akdag M, Yuki Y, Gao X, O'hUigin C, Raghavan M, Wolinsky S, Bream JH, Duggal P, Martinson J, Michael NL, Kirk GD, Buchbinder SP, Haas D, Goedert JJ, Deeks SG, Fellay J, Walker B, Goulder P, Cresswell P, Elliott T, Sette A, Carlson J, Carrington M. PMID: 33097667; PMCID: PMC7668082.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Mining for humoral correlates of HIV control and latent reservoir size. PLoS Pathog. 2020 10; 16(10):e1008868.
Das J, Devadhasan A, Linde C, Broge T, Sassic J, Mangano M, O'Keefe S, Suscovich T, Streeck H, Irrinki A, Pohlmeyer C, Min-Oo G, Lin S, Weiner JA, Cihlar T, Ackerman ME, Julg B, Deeks S, Lauffenburger DA, Alter G. PMID: 33048992; PMCID: PMC7553335.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Association of Viral Persistence and Atherosclerosis in Adults With Treated HIV Infection. JAMA Netw Open. 2020 10 01; 3(10):e2018099.
McLaughlin MM, Ma Y, Scherzer R, Rahalkar S, Martin JN, Mills C, Milush J, Deeks SG, Hsue PY. PMID: 33119103; PMCID: PMC7596582.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
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Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir. Elife. 2020 09 29; 9.
Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA, Palmer S, Greene WC, Roan NR. PMID: 32990219; PMCID: PMC7524554.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
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The Current State of HIV and Aging: Findings Presented at the 10th International Workshop on HIV and Aging. AIDS Res Hum Retroviruses. 2020 12; 36(12):973-981.
Shiau S, Bender AA, O'Halloran JA, Sundermann E, Aggarwal J, Althoff KN, Baker JV, Deeks S, Fried LP, Karpiak S, Karris MY, Marcotte TD, Nachega JB, Margolick JB, Erlandson KM, Moore DJ. PMID: 32847368; PMCID: PMC7703090.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCellsPHPublic Health
-
Everolimus, an mTORC1/2 inhibitor, in ART-suppressed individuals who received solid organ transplantation: A prospective study. Am J Transplant. 2021 05; 21(5):1765-1779.
Henrich TJ, Schreiner C, Cameron C, Hogan LE, Richardson B, Rutishauser RL, Deitchman AN, Chu S, Rogers R, Thanh C, Gibson EA, Zarinsefat A, Bakkour S, Aweeka F, Busch MP, Liegler T, Baker C, Milush J, Deeks SG, Stock PG. PMID: 32780519; PMCID: PMC9177122.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
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Filgotinib suppresses HIV-1-driven gene transcription by inhibiting HIV-1 splicing and T cell activation. J Clin Invest. 2020 09 01; 130(9):4969-4984.
Yeh YJ, Jenike KM, Calvi RM, Chiarella J, Hoh R, Deeks SG, Ho YC. PMID: 32573496; PMCID: PMC7456222.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Distinct viral reservoirs in individuals with spontaneous control of HIV-1. Nature. 2020 09; 585(7824):261-267.
Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, Milush J, Bertagnolli LN, Sweet SE, Varriale JA, Burbelo PD, Chun TW, Laird GM, Serrao E, Engelman AN, Carrington M, Siliciano RF, Siliciano JM, Deeks SG, Walker BD, Lichterfeld M, Yu XG. PMID: 32848246; PMCID: PMC7837306.
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PubMed Mentions:
160 Fields:
Translation:
HumansCells
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Universal PCR and antibody testing demonstrate little to no transmission of SARS-CoV-2 in a rural community. medRxiv. 2020 Aug 17.
Appa A, Takahashi S, Rodriguez-Barraquer I, Chamie G, Sawyer A, Consortium C, Duarte E, Hakim J, Turcios K, Vinden J, Janson O, Manglik A, Peluso MJ, Deeks SG, Henrich TJ, Torres L, Rodgers M, Hackett J, Chiu C, Havlir D, Greenhouse B. PMID: 32839781; PMCID: PMC7444294.
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Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA. Proc Natl Acad Sci U S A. 2020 08 04; 117(31):18692-18700.
Simonetti FR, White JA, Tumiotto C, Ritter KD, Cai M, Gandhi RT, Deeks SG, Howell BJ, Montaner LJ, Blankson JN, Martin A, Laird GM, Siliciano RF, Mellors JW, Siliciano JD. PMID: 32690683; PMCID: PMC7414172.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection. J Virol. 2020 07 01; 94(14).
Scharf L, Tauriainen J, Buggert M, Hartogensis W, Nolan DJ, Deeks SG, Salemi M, Hecht FM, Karlsson AC. PMID: 32350076; PMCID: PMC7343205.
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PubMed Mentions:
5 Fields:
Translation:
HumansCellsCTClinical Trials
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Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy. J Clin Invest. 2020 07 01; 130(7):3543-3559.
Antar AA, Jenike KM, Jang S, Rigau DN, Reeves DB, Hoh R, Krone MR, Keruly JC, Moore RD, Schiffer JT, Nonyane BA, Hecht FM, Deeks SG, Siliciano JD, Ho YC, Siliciano RF. PMID: 32191639; PMCID: PMC7324206.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansCellsCTClinical Trials
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Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop. Pathog Immun. 2020; 5(1):143-174.
Gabuzda D, Jamieson BD, Collman RG, Lederman MM, Burdo TH, Deeks SG, Dittmer DP, Fox HS, Funderburg NT, Pahwa SG, Pandrea I, Wilson CC, Hunt PW. PMID: 32856008; PMCID: PMC7449259.
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PubMed Mentions:
26
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FOXO1 promotes HIV latency by suppressing ER stress in T cells. Nat Microbiol. 2020 09; 5(9):1144-1157.
Vallejo-Gracia A, Chen IP, Perrone R, Besnard E, Boehm D, Battivelli E, Tezil T, Krey K, Raymond KA, Hull PA, Walter M, Habrylo I, Cruz A, Deeks S, Pillai S, Verdin E, Ott M. PMID: 32541947; PMCID: PMC7483895.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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The immune response fails to control HIV early in initial virus spread. J Clin Invest. 2020 06 01; 130(6):2803-2805.
Cohn LB, Deeks SG. PMID: 32338639; PMCID: PMC7259984.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Impact of first-line antiretroviral therapy regimens on the restoration of the CD4/CD8 ratio in the CNICS cohort. J Antimicrob Chemother. 2020 06 01; 75(6):1604-1610.
Herrera S, Fernandez-Felix BM, Hunt PW, Deeks SG, Sainz T, Heath SL, Achenbach CJ, Rodríguez B, Mathews C, Christopoulos K, Mayer K, Napravnik S, Moreno S, Serrano-Villar S. PMID: 32211777; PMCID: PMC7225872.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Single-cell transcriptional landscapes reveal HIV-1-driven aberrant host gene transcription as a potential therapeutic target. Sci Transl Med. 2020 05 13; 12(543).
Liu R, Yeh YJ, Varabyou A, Collora JA, Sherrill-Mix S, Talbot CC, Mehta S, Albrecht K, Hao H, Zhang H, Pollack RA, Beg SA, Calvi RM, Hu J, Durand CM, Ambinder RF, Hoh R, Deeks SG, Chiarella J, Spudich S, Douek DC, Bushman FD, Pertea M, Ho YC. PMID: 32404504; PMCID: PMC7453882.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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'Rinse and Replace': Boosting T Cell Turnover To Reduce HIV-1 Reservoirs. Trends Immunol. 2020 06; 41(6):466-480.
Grossman Z, Singh NJ, Simonetti FR, Lederman MM, Douek DC, Deeks SG, Contributing authors. PMID: 32414695.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Association between statin use, atherosclerosis, and mortality in HIV-infected adults. PLoS One. 2020; 15(4):e0232636.
Phan BAP, Ma Y, Scherzer R, Deeks SG, Hsue PY. PMID: 32353062; PMCID: PMC7192415.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. PLoS Pathog. 2020 04; 16(4):e1008450.
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. PMID: 32353080; PMCID: PMC7192375.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay. J Acquir Immune Defic Syndr. 2020 04 15; 83(5):530-537.
Lee SA, Telwatte S, Hatano H, Kashuba ADM, Cottrell ML, Hoh R, Liegler TJ, Stephenson S, Somsouk M, Hunt PW, Deeks SG, Yukl S, Savic RM. PMID: 32168200; PMCID: PMC7286563.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies. Cell Host Microbe. 2020 04 08; 27(4):519-530.
Cohn LB, Chomont N, Deeks SG. PMID: 32272077; PMCID: PMC7219958.
View in:
PubMed Mentions:
112 Fields:
Translation:
HumansAnimalsCells
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High levels of genetically intact HIV in HLA-DR+ memory T cells indicates their value for reservoir studies. AIDS. 2020 04 01; 34(5):659-668.
Horsburgh BA, Lee E, Hiener B, Eden JS, Schlub TE, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek DC, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 31913161; PMCID: PMC7071960.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches. Front Immunol. 2020; 11:519.
Paiardini M, Dhodapkar K, Harper J, Deeks SG, Ahmed R. PMID: 32296432; PMCID: PMC7138010.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nat Immunol. 2020 05; 21(5):578-587.
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B. PMID: 32231298; PMCID: PMC7183435.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Circulating CD30+CD4+ T Cells Increase Before Human Immunodeficiency Virus Rebound After Analytical Antiretroviral Treatment Interruption. J Infect Dis. 2020 03 16; 221(7):1146-1155.
Prator CA, Thanh C, Kumar S, Pan T, Peluso MJ, Bosch R, Jones N, Milush JM, Bakkour S, Stone M, Busch MP, Deeks SG, Hunt PW, Henrich TJ. PMID: 31677350; PMCID: PMC7325710.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Plasma tissue factor and immune activation are associated with carotid intima-media thickness progression in treated HIV infection. AIDS. 2020 03 15; 34(4):519-528.
Hsu DC, Ma YF, Narwan A, Rahalkar S, Rupert A, Scherzer R, Mills C, Deeks S, Sereti I, Hsue PY. PMID: 31634197.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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CXCR4-Using HIV Strains Predominate in Naive and Central Memory CD4+ T Cells in People Living with HIV on Antiretroviral Therapy: Implications for How Latency Is Established and Maintained. J Virol. 2020 02 28; 94(6).
Roche M, Tumpach C, Symons J, Gartner M, Anderson JL, Khoury G, Cashin K, Cameron PU, Churchill MJ, Deeks SG, Gorry PR, Lewin SR. PMID: 31852784; PMCID: PMC7158712.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Differential decay of intact and defective proviral DNA in HIV-1-infected individuals on suppressive antiretroviral therapy. JCI Insight. 2020 02 27; 5(4).
Peluso MJ, Bacchetti P, Ritter KD, Beg S, Lai J, Martin JN, Hunt PW, Henrich TJ, Siliciano JD, Siliciano RF, Laird GM, Deeks SG. PMID: 32045386; PMCID: PMC7101154.
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PubMed Mentions:
94 Fields:
Translation:
HumansCells
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Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1. J Virus Erad. 2020 Feb 20; 6(1):19-26.
Peluso MJ, Thanh C, Prator CA, Hogan LE, Arechiga VM, Stephenson S, Norris PJ, Di Germanio C, Fuchs D, Zetterberg H, Deeks SG, Gisslén M, Price RW, Henrich TJ. PMID: 32175087; PMCID: PMC7043898.
View in:
PubMed Mentions:
5
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A collaborative, multidisciplinary approach to HIV transmission risk mitigation during analytic treatment interruption. J Virus Erad. 2020 Feb 20; 6(1):34-37.
Peluso MJ, Dee L, Campbell D, Taylor J, Hoh R, Rutishauser RL, Sauceda J, Deeks SG, Dubé K. PMID: 32175090; PMCID: PMC7043899.
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PubMed Mentions:
24
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Human Immunodeficiency Virus (HIV)-Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy. J Infect Dis. 2020 02 18; 221(5):744-755.
Anderson JL, Khoury G, Fromentin R, Solomon A, Chomont N, Sinclair E, Milush JM, Hartogensis W, Bacchetti P, Roche M, Tumpach C, Gartner M, Pitman MC, Epling CL, Hoh R, Hecht FM, Somsouk M, Cameron PU, Deeks SG, Lewin SR. PMID: 31796951; PMCID: PMC7026892.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells. Nat Immunol. 2020 03; 21(3):274-286.
Wang Y, Lifshitz L, Gellatly K, Vinton CL, Busman-Sahay K, McCauley S, Vangala P, Kim K, Derr A, Jaiswal S, Kucukural A, McDonel P, Hunt PW, Greenough T, Houghton J, Somsouk M, Estes JD, Brenchley JM, Garber M, Deeks SG, Luban J. PMID: 32066947; PMCID: PMC7044076.
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PubMed Mentions:
48 Fields:
Translation:
HumansCells
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Different human resting memory CD4+ T cell subsets show similar low inducibility of latent HIV-1 proviruses. Sci Transl Med. 2020 01 29; 12(528).
Kwon KJ, Timmons AE, Sengupta S, Simonetti FR, Zhang H, Hoh R, Deeks SG, Siliciano JD, Siliciano RF. PMID: 31996465; PMCID: PMC7875249.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Impact of Antiretroviral Therapy Duration on HIV-1 Infection of T Cells within Anatomic Sites. J Virol. 2020 01 17; 94(3).
Lee E, von Stockenstrom S, Morcilla V, Odevall L, Hiener B, Shao W, Hartogensis W, Bacchetti P, Milush J, Liegler T, Sinclair E, Hatano H, Hoh R, Somsouk M, Hunt P, Boritz E, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 31723024; PMCID: PMC7000983.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells. Sci Transl Med. 2019 12 18; 11(523).
Nguyen S, Deleage C, Darko S, Ransier A, Truong DP, Agarwal D, Japp AS, Wu VH, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada PM, Ablanedo-Terrazas Y, Gostick E, Hoxie JA, Zhang NR, Naji A, Reyes-Terán G, Estes JD, Price DA, Douek DC, Deeks SG, Buggert M, Betts MR. PMID: 31852798; PMCID: PMC7265335.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Why and where an HIV cure is needed and how it might be achieved. Nature. 2019 12; 576(7787):397-405.
Ndung'u T, McCune JM, Deeks SG. PMID: 31853080; PMCID: PMC8052635.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors. Proc Natl Acad Sci U S A. 2019 12 17; 116(51):25891-25899.
Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, Hu WS, Luke B, Hasson JM, Niyongabo A, Capoferri AA, Keele BF, Milush J, Hoh R, Deeks SG, Maldarelli F, Hughes SH, Coffin JM, Rausch JW, Mellors JW, Kearney MF. PMID: 31776247; PMCID: PMC6925994.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
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Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4+ T Cells. J Virol. 2019 12 15; 93(24).
Kulpa DA, Talla A, Brehm JH, Ribeiro SP, Yuan S, Bebin-Blackwell AG, Miller M, Barnard R, Deeks SG, Hazuda D, Chomont N, Sékaly RP. PMID: 31578289; PMCID: PMC6880164.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Author Correction: CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome. Nat Immunol. 2019 Nov; 20(11):1555.
Kulkarni S, Lied A, Kulkarni V, Rucevic M, Martin MP, Walker-Sperling V, Anderson SK, Ewy R, Singh S, Nguyen H, McLaren PJ, Viard M, Naranbhai V, Zou C, Lin Z, Gatanaga H, Oka S, Takiguchi M, Thio CL, Margolick J, Kirk GD, Goedert JJ, Hoots WK, Deeks SG, Haas DW, Michael N, Walker B, Le Gall S, Chowdhury FZ, Yu XG, Carrington M. PMID: 31548709.
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PubMed Mentions: Fields:
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Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. Cell. 2019 10 31; 179(4):880-894.e10.
Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. PMID: 31668804; PMCID: PMC6922308.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals. PLoS Pathog. 2019 10; 15(10):e1008074.
Wonderlich ER, Subramanian K, Cox B, Wiegand A, Lackman-Smith C, Bale MJ, Stone M, Hoh R, Kearney MF, Maldarelli F, Deeks SG, Busch MP, Ptak RG, Kulpa DA. PMID: 31609991; PMCID: PMC6812841.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):211-219.
Deguit CDT, Hough M, Hoh R, Krone M, Pilcher CD, Martin JN, Deeks SG, McCune JM, Hunt PW, Rutishauser RL. PMID: 31513075; PMCID: PMC6746248.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy. Front Microbiol. 2019; 10:2214.
Lee E, Bacchetti P, Milush J, Shao W, Boritz E, Douek D, Fromentin R, Liegler T, Hoh R, Deeks SG, Hecht FM, Chomont N, Palmer S. PMID: 31611857; PMCID: PMC6775493.
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PubMed Mentions:
26
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Statistical analysis of single-copy assays when some observations are zero. J Virus Erad. 2019 Sep 18; 5(3):167-173.
Bacchetti P, Bosch RJ, Scully EP, Deng X, Busch MP, Deeks SG, Lewin SR. PMID: 31700665; PMCID: PMC6816121.
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PubMed Mentions:
4
-
HIV elite control is associated with reduced TRAILshort expression. AIDS. 2019 09 01; 33(11):1757-1763.
Paim AC, Cummins NW, Natesampillai S, Garcia-Rivera E, Kogan N, Neogi U, Sönnerborg A, Sperk M, Bren GD, Deeks S, Polley E, Badley AD. PMID: 31149947; PMCID: PMC6873462.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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HIV-Specific T Cell Responses Are Highly Stable on Antiretroviral Therapy. Mol Ther Methods Clin Dev. 2019 Dec 13; 15:9-17.
Xu Y, Trumble IM, Warren JA, Clutton G, Abad-Fernandez M, Kirchnerr J, Adimora AA, Deeks SG, Margolis DM, Kuruc JD, Gay CL, Archin NM, Mollan KR, Hudgens M, Goonetilleke N. PMID: 31534983; PMCID: PMC6745511.
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PubMed Mentions:
16
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HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy. J Clin Invest. 2019 07 30; 129(11):4629-4642.
McManus WR, Bale MJ, Spindler J, Wiegand A, Musick A, Patro SC, Sobolewski MD, Musick VK, Anderson EM, Cyktor JC, Halvas EK, Shao W, Wells D, Wu X, Keele BF, Milush JM, Hoh R, Mellors JW, Hughes SH, Deeks SG, Coffin JM, Kearney MF. PMID: 31361603; PMCID: PMC6819093.
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PubMed Mentions:
55 Fields:
Translation:
HumansCellsCTClinical Trials
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Risk to Nonparticipants in HIV Remission Studies With Treatment Interruption: A Symposium. J Infect Dis. 2019 07 02; 220(220 Suppl 1):S1-S4.
Eyal N, Deeks SG. PMID: 31264687; PMCID: PMC6603969.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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How Unavoidable Are Analytical Treatment Interruptions in HIV Cure-Related Studies? J Infect Dis. 2019 07 02; 220(220 Suppl 1):S24-S26.
Margolis DM, Deeks SG. PMID: 31264691; PMCID: PMC6636248.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
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CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome. Nat Immunol. 2019 07; 20(7):824-834.
Kulkarni S, Lied A, Kulkarni V, Rucevic M, Martin MP, Walker-Sperling V, Anderson SK, Ewy R, Singh S, Nguyen H, McLaren PJ, Viard M, Naranbhai V, Zou C, Lin Z, Gatanaga H, Oka S, Takiguchi M, Thio CL, Margolick J, Kirk GD, Goedert JJ, Hoots WK, Deeks SG, Haas DW, Michael N, Walker B, Le Gall S, Chowdhury FZ, Yu XG, Carrington M. PMID: 31209403; PMCID: PMC6584055.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Safety and Impact of Low-dose Methotrexate on Endothelial Function and Inflammation in Individuals With Treated Human Immunodeficiency Virus: AIDS Clinical Trials Group Study A5314. Clin Infect Dis. 2019 05 17; 68(11):1877-1886.
Hsue PY, Ribaudo HJ, Deeks SG, Bell T, Ridker PM, Fichtenbaum C, Daar ES, Havlir D, Yeh E, Tawakol A, Lederman M, Currier JS, Stein JH. PMID: 30219823; PMCID: PMC6522677.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCellsCTClinical Trials
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Unusual Cysteine Content in V1 Region of gp120 From an Elite Suppressor That Produces Broadly Neutralizing Antibodies. Front Immunol. 2019; 10:1021.
Hutchinson JM, Mesa KA, Alexander DL, Yu B, O'Rourke SM, Limoli KL, Wrin T, Deeks SG, Berman PW. PMID: 31156622; PMCID: PMC6530427.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults. J Am Heart Assoc. 2019 05 07; 8(9):e011037.
Sinha A, Ma Y, Scherzer R, Rahalkar S, Neilan BD, Crane H, Drozd D, Martin J, Deeks SG, Hunt P, Hsue PY. PMID: 31030595; PMCID: PMC6512101.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
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CD32-RNA Co-localizes with HIV-RNA in CD3+ Cells Found within Gut Tissues from Viremic and ART-Suppressed Individuals. Pathog Immun. 2019; 4(1):147-160.
Vásquez JJ, Aguilar-Rodriguez BL, Rodriguez L, Hogan LE, Somsouk M, McCune JM, Deeks SG, Laszik ZG, Hunt PW, Henrich TJ. PMID: 31139759; PMCID: PMC6508427.
View in:
PubMed Mentions:
9
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Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size. PLoS Comput Biol. 2019 04; 15(4):e1006849.
Rosenbloom DIS, Bacchetti P, Stone M, Deng X, Bosch RJ, Richman DD, Siliciano JD, Mellors JW, Deeks SG, Ptak RG, Hoh R, Keating SM, Dimapasoc M, Massanella M, Lai J, Sobolewski MD, Kulpa DA, Busch MP, Reservoir Assay Validation and Evaluation Network (RAVEN) Study Group. PMID: 30978183; PMCID: PMC6481870.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members. Elife. 2019 04 09; 8.
Gonzalo-Gil E, Rapuano PB, Ikediobi U, Leibowitz R, Mehta S, Coskun AK, Porterfield JZ, Lampkin TD, Marconi VC, Rimland D, Walker BD, Deeks S, Sutton RE. PMID: 30964004; PMCID: PMC6456299.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control. J Virol. 2019 04 01; 93(7).
Pohlmeyer CW, Gonzalez VD, Irrinki A, Ramirez RN, Li L, Mulato A, Murry JP, Arvey A, Hoh R, Deeks SG, Kukolj G, Cihlar T, Pflanz S, Nolan GP, Min-Oo G. PMID: 30700608; PMCID: PMC6430550.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Emulating a trial of joint dynamic strategies: An application to monitoring and treatment of HIV-positive individuals. Stat Med. 2019 06 15; 38(13):2428-2446.
Caniglia EC, Robins JM, Cain LE, Sabin C, Logan R, Abgrall S, Mugavero MJ, Hernández-Díaz S, Meyer L, Seng R, Drozd DR, Seage Iii GR, Bonnet F, Le Marec F, Moore RD, Reiss P, van Sighem A, Mathews WC, Jarrín I, Alejos B, Deeks SG, Muga R, Boswell SL, Ferrer E, Eron JJ, Gill J, Pacheco A, Grinsztejn B, Napravnik S, Jose S, Phillips A, Justice A, Tate J, Bucher HC, Egger M, Furrer H, Miro JM, Casabona J, Porter K, Touloumi G, Crane H, Costagliola D, Saag M, Hernán MA. PMID: 30883859; PMCID: PMC6499640.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Recommendations for analytical antiretroviral treatment interruptions in HIV research trials-report of a consensus meeting. Lancet HIV. 2019 04; 6(4):e259-e268.
Julg B, Dee L, Ananworanich J, Barouch DH, Bar K, Caskey M, Colby DJ, Dawson L, Dong KL, Dubé K, Eron J, Frater J, Gandhi RT, Geleziunas R, Goulder P, Hanna GJ, Jefferys R, Johnston R, Kuritzkes D, Li JZ, Likhitwonnawut U, van Lunzen J, Martinez-Picado J, Miller V, Montaner LJ, Nixon DF, Palm D, Pantaleo G, Peay H, Persaud D, Salzwedel J, Salzwedel K, Schacker T, Sheikh V, Søgaard OS, Spudich S, Stephenson K, Sugarman J, Taylor J, Tebas P, Tiemessen CT, Tressler R, Weiss CD, Zheng L, Robb ML, Michael NL, Mellors JW, Deeks SG, Walker BD. PMID: 30885693; PMCID: PMC6688772.
View in:
PubMed Mentions:
102 Fields:
Translation:
Humans
-
Sex-Based Differences in Human Immunodeficiency Virus Type 1 Reservoir Activity and Residual Immune Activation. J Infect Dis. 2019 03 15; 219(7):1084-1094.
Scully EP, Gandhi M, Johnston R, Hoh R, Lockhart A, Dobrowolski C, Pagliuzza A, Milush JM, Baker CA, Girling V, Ellefson A, Gorelick R, Lifson J, Altfeld M, Alter G, Cedars M, Solomon A, Lewin SR, Karn J, Chomont N, Bacchetti P, Deeks SG. PMID: 30371873; PMCID: PMC6784502.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
-
PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals. Nat Commun. 2019 02 18; 10(1):814.
Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N. PMID: 30778080; PMCID: PMC6379401.
View in:
PubMed Mentions:
110 Fields:
Translation:
HumansCells
-
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses. Nature. 2019 02; 566(7742):120-125.
Bruner KM, Wang Z, Simonetti FR, Bender AM, Kwon KJ, Sengupta S, Fray EJ, Beg SA, Antar AAR, Jenike KM, Bertagnolli LN, Capoferri AA, Kufera JT, Timmons A, Nobles C, Gregg J, Wada N, Ho YC, Zhang H, Margolick JB, Blankson JN, Deeks SG, Bushman FD, Siliciano JD, Laird GM, Siliciano RF. PMID: 30700913; PMCID: PMC6447073.
View in:
PubMed Mentions:
335 Fields:
Translation:
HumansCells
-
Reiterative Enrichment and Authentication of CRISPRi Targets (REACT) identifies the proteasome as a key contributor to HIV-1 latency. PLoS Pathog. 2019 01; 15(1):e1007498.
Li Z, Wu J, Chavez L, Hoh R, Deeks SG, Pillai SK, Zhou Q. PMID: 30645648; PMCID: PMC6333332.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
-
Stimulant Use and Viral Suppression in the Era of Universal Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2019 01 01; 80(1):89-93.
Carrico AW, Hunt PW, Neilands TB, Dilworth SE, Martin JN, Deeks SG, Riley ED. PMID: 30272634; PMCID: PMC6289664.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Unique Circulating MicroRNA Profiles in HIV Infection. J Acquir Immune Defic Syndr. 2018 12 15; 79(5):644-650.
Narla V, Bhakta N, Freedman JE, Tanriverdi K, Maka K, Deeks SG, Ganz P, Hsue P. PMID: 30204717.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Transient loss of detectable HIV-1 RNA following brentuximab vedotin anti-CD30 therapy for Hodgkin lymphoma. Blood Adv. 2018 12 11; 2(23):3479-3482.
Wang CC, Thanh C, Gibson EA, Ball-Burack M, Hogan LE, Descours B, Jones N, Carvidi AB, Munter S, Bakkour S, Busch MP, Milush JM, Deeks SG, Henrich TJ. PMID: 30530753; PMCID: PMC6290106.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
IL-1β Inhibition Reduces Atherosclerotic Inflammation in HIV Infection. J Am Coll Cardiol. 2018 12 04; 72(22):2809-2811.
Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A. PMID: 30497570; PMCID: PMC8723182.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency. PLoS Pathog. 2018 11; 14(11):e1007357.
Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA. PMID: 30440043; PMCID: PMC6237391.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
-
The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. J Infect Dis. 2018 11 05; 218(12):1954-1963.
Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. PMID: 30085241; PMCID: PMC6217727.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansCells
-
HIV control: Is getting there the same as staying there? PLoS Pathog. 2018 11; 14(11):e1007222.
Goulder P, Deeks SG. PMID: 30383857; PMCID: PMC6211749.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
-
Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase IIb Trial. Clin Pharmacol Ther. 2019 03; 105(3):692-702.
Lee SA, Elliott JH, McMahon J, Hartogenesis W, Bumpus NN, Lifson JD, Gorelick RJ, Bacchetti P, Deeks SG, Lewin SR, Savic RM. PMID: 30137649; PMCID: PMC6379104.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCellsCTClinical Trials
-
Inconsistent HIV reservoir dynamics and immune responses following anti-PD-1 therapy in cancer patients with HIV infection. Ann Oncol. 2018 10 01; 29(10):2141-2142.
Scully EP, Rutishauser RL, Simoneau CR, Delagrèverie H, Euler Z, Thanh C, Li JZ, Hartig H, Bakkour S, Busch M, Alter G, Marty FM, Wang CC, Deeks SG, Lorch J, Henrich TJ. PMID: 30032204; PMCID: PMC6225895.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Variation in cell-associated unspliced HIV RNA on antiretroviral therapy is associated with the circadian regulator brain-and-muscle-ARNT-like-1. AIDS. 2018 09 24; 32(15):2119-2128.
Chang CC, Naranbhai V, Stern J, Roche M, Dantanarayana A, Ke R, Tennakoon S, Solomon A, Hoh R, Hartogensis W, Hecht FM, Sikaris K, Price DJ, Elliott JH, Deeks SG, Churchill M, Cameron PU, Hengartner N, Perelson AS, Lewin SR. PMID: 30005017; PMCID: PMC6173794.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCellsCTClinical Trials
-
Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection. J Infect Dis. 2018 09 22; 218(9):1394-1403.
Lidofsky A, Holmes JA, Feeney ER, Kruger AJ, Salloum S, Zheng H, Seguin IS, Altinbas A, Masia R, Corey KE, Gustafson JL, Schaefer EA, Hunt PW, Deeks S, Somsouk M, Chew KW, Chung RT, Alatrakchi N. PMID: 29868909; PMCID: PMC6151081.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Ethical issues in HIV remission trials. Curr Opin HIV AIDS. 2018 09; 13(5):422-427.
Eyal N, Holtzman LG, Deeks SG. PMID: 30015634; PMCID: PMC6112842.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
Estrogen receptor-1 is a key regulator of HIV-1 latency that imparts gender-specific restrictions on the latent reservoir. Proc Natl Acad Sci U S A. 2018 08 14; 115(33):E7795-E7804.
Das B, Dobrowolski C, Luttge B, Valadkhan S, Chomont N, Johnston R, Bacchetti P, Hoh R, Gandhi M, Deeks SG, Scully E, Karn J. PMID: 30061382; PMCID: PMC6099847.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCells
-
Maximising the global health impact of future HIV cure-related interventions through advance planning. J Virus Erad. 2018 Jul 01; 4(3):182-185.
Brown R, Deeks SG, Eyal N. PMID: 30050682; PMCID: PMC6038126.
View in:
PubMed Mentions:
2
-
Changes in Inflammation but Not in T-Cell Activation Precede Non-AIDS-Defining Events in a Case-Control Study of Patients on Long-term Antiretroviral Therapy. J Infect Dis. 2018 06 20; 218(2):239-248.
Angelidou K, Hunt PW, Landay AL, Wilson CC, Rodriguez B, Deeks SG, Bosch RJ, Lederman MM. PMID: 29309629; PMCID: PMC6009591.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue. Sci Immunol. 2018 06 01; 3(24).
Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR. PMID: 29858286; PMCID: PMC6357781.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
-
A randomized, controlled trial of mindfulness-based stress reduction in HIV infection. Brain Behav Immun. 2018 10; 73:331-339.
Hecht FM, Moskowitz JT, Moran P, Epel ES, Bacchetti P, Acree M, Kemeny ME, Mendes WB, Duncan LG, Weng H, Levy JA, Deeks SG, Folkman S. PMID: 29842903; PMCID: PMC7656978.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
-
Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells. Elife. 2018 05 01; 7.
Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. PMID: 29714165; PMCID: PMC5973828.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansCells
-
Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease. PLoS Pathog. 2018 04; 14(4):e1006973.
Buggert M, Nguyen S, McLane LM, Steblyanko M, Anikeeva N, Paquin-Proulx D, Del Rio Estrada PM, Ablanedo-Terrazas Y, Noyan K, Reuter MA, Demers K, Sandberg JK, Eller MA, Streeck H, Jansson M, Nowak P, Sönnerborg A, Canaday DH, Naji A, Wherry EJ, Robb ML, Deeks SG, Reyes-Teran G, Sykulev Y, Karlsson AC, Betts MR. PMID: 29652923; PMCID: PMC5919077.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. J Clin Invest. 2018 05 01; 128(5):1903-1912.
Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M. PMID: 29461980; PMCID: PMC5919796.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCellsCTClinical Trials
-
Anti-Human Immunodeficiency Virus Antibodies in the Cerebrospinal Fluid: Evidence of Early Treatment Impact on Central Nervous System Reservoir? J Infect Dis. 2018 03 13; 217(7):1024-1032.
Burbelo PD, Price RW, Hagberg L, Hatano H, Spudich S, Deeks SG, Gisslén M. PMID: 29401308; PMCID: PMC5939835.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function. PLoS Pathog. 2018 03; 14(3):e1006806.
Chitre AS, Kattah MG, Rosli YY, Pao M, Deswal M, Deeks SG, Hunt PW, Abdel-Mohsen M, Montaner LJ, Kim CC, Ma A, Somsouk M, McCune JM. PMID: 29505600; PMCID: PMC5854440.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Increased HIV-1 transcriptional activity and infectious burden in peripheral blood and gut-associated CD4+ T cells expressing CD30. PLoS Pathog. 2018 02; 14(2):e1006856.
Hogan LE, Vasquez J, Hobbs KS, Hanhauser E, Aguilar-Rodriguez B, Hussien R, Thanh C, Gibson EA, Carvidi AB, Smith LCB, Khan S, Trapecar M, Sanjabi S, Somsouk M, Stoddart CA, Kuritzkes DR, Deeks SG, Henrich TJ. PMID: 29470552; PMCID: PMC5823470.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
-
Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection. J Virol. 2018 02 15; 92(4).
Adland E, Hill M, Lavandier N, Csala A, Edwards A, Chen F, Radkowski M, Kowalska JD, Paraskevis D, Hatzakis A, Valenzuela-Ponce H, Pfafferott K, Williams I, Pellegrino P, Borrow P, Mori M, Rockstroh J, Prado JG, Mothe B, Dalmau J, Martinez-Picado J, Tudor-Williams G, Frater J, Stryhn A, Buus S, Teran GR, Mallal S, John M, Buchbinder S, Kirk G, Martin J, Michael N, Fellay J, Deeks S, Walker B, Avila-Rios S, Cole D, Brander C, Carrington M, Goulder P. PMID: 29167337; PMCID: PMC5790925.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA. PLoS One. 2018; 13(1):e0191613.
Ferdin J, Goricar K, Dolžan V, Plemenitaš A, Martin JN, Peterlin BM, Deeks SG, Lenassi M. PMID: 29364927; PMCID: PMC5783402.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans
-
Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection. J Immunol. 2018 03 01; 200(5):1876-1888.
Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. PMID: 29352005; PMCID: PMC5821568.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells. Science. 2018 01 05; 359(6371):86-90.
Ramsuran V, Naranbhai V, Horowitz A, Qi Y, Martin MP, Yuki Y, Gao X, Walker-Sperling V, Del Prete GQ, Schneider DK, Lifson JD, Fellay J, Deeks SG, Martin JN, Goedert JJ, Wolinsky SM, Michael NL, Kirk GD, Buchbinder S, Haas D, Ndung'u T, Goulder P, Parham P, Walker BD, Carlson JM, Carrington M. PMID: 29302013; PMCID: PMC5933048.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansCells
-
The end of HIV: Still a very long way to go, but progress continues. PLoS Med. 2017 Nov; 14(11):e1002466.
Deeks SG, Lewin SR, Bekker LG. PMID: 29190733; PMCID: PMC5708775.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Detection of HIV-1-specific gastrointestinal tissue resident CD8+ T-cells in chronic infection. Mucosal Immunol. 2018 05; 11(3):909-920.
Kiniry BE, Li S, Ganesh A, Hunt PW, Somsouk M, Skinner PJ, Deeks SG, Shacklett BL. PMID: 29139476; PMCID: PMC5953759.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection. J Virol. 2017 12 01; 91(23).
Teigler JE, Zelinskyy G, Eller MA, Bolton DL, Marovich M, Gordon AD, Alrubayyi A, Alter G, Robb ML, Martin JN, Deeks SG, Michael NL, Dittmer U, Streeck H. PMID: 28904197; PMCID: PMC5686724.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
-
HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study. PLoS Med. 2017 Nov; 14(11):e1002417.
Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, McCune JM, Spindler J, Metcalf-Pate K, Hobbs KS, Thanh C, Gibson EA, Kuritzkes DR, Siliciano RF, Price RW, Richman DD, Chomont N, Siliciano JD, Mellors JW, Yukl SA, Blankson JN, Liegler T, Deeks SG. PMID: 29112956; PMCID: PMC5675377.
View in:
PubMed Mentions:
122 Fields:
Translation:
HumansCellsPHPublic Health
-
An Optimized and Validated Method for Isolation and Characterization of Lymphocytes from HIV+ Human Gut Biopsies. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S31-S39.
Trapecar M, Khan S, Roan NR, Chen TH, Telwatte S, Deswal M, Pao M, Somsouk M, Deeks SG, Hunt PW, Yukl S, Sanjabi S. PMID: 28882052; PMCID: PMC5684666.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Association of HIV-1 Gag-Specific IgG Antibodies With Natural Control of HIV-1 Infection in Individuals Not Carrying HLA-B*57: 01 Is Only Observed in Viremic Controllers. J Acquir Immune Defic Syndr. 2017 11 01; 76(3):e90-e92.
Tjiam MC, Morshidi MA, Sariputra L, Martin JN, Deeks SG, Tan DBA, Lee S, Fernandez S, French MA. PMID: 28604502; PMCID: PMC5634911.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection. J Virol. 2017 11 15; 91(22).
Leitman EM, Willberg CB, Tsai MH, Chen H, Buus S, Chen F, Riddell L, Haas D, Fellay J, Goedert JJ, Piechocka-Trocha A, Walker BD, Martin J, Deeks S, Wolinsky SM, Martinson J, Martin M, Qi Y, Sáez-Cirión A, Yang OO, Matthews PC, Carrington M, Goulder PJR. PMID: 28878089; PMCID: PMC5660483.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCellsCTClinical Trials
-
Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants. Cell Rep. 2017 Oct 17; 21(3):813-822.
Hiener B, Horsburgh BA, Eden JS, Barton K, Schlub TE, Lee E, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. PMID: 29045846; PMCID: PMC5960642.
View in:
PubMed Mentions:
223 Fields:
Translation:
HumansCells
-
Defining total-body AIDS-virus burden with implications for curative strategies. Nat Med. 2017 Nov; 23(11):1271-1276.
Estes JD, Kityo C, Ssali F, Swainson L, Makamdop KN, Del Prete GQ, Deeks SG, Luciw PA, Chipman JG, Beilman GJ, Hoskuldsson T, Khoruts A, Anderson J, Deleage C, Jasurda J, Schmidt TE, Hafertepe M, Callisto SP, Pearson H, Reimann T, Schuster J, Schoephoerster J, Southern P, Perkey K, Shang L, Wietgrefe SW, Fletcher CV, Lifson JD, Douek DC, McCune JM, Haase AT, Schacker TW. PMID: 28967921; PMCID: PMC5831193.
View in:
PubMed Mentions:
227 Fields:
Translation:
HumansCells
-
Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers. Retrovirology. 2017 Aug 22; 14(1):41.
de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA. PMID: 28830571; PMCID: PMC5568399.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Terminal differentiation of T cells is strongly associated with CMV infection and increased in HIV-positive individuals on ART and lifestyle matched controls. PLoS One. 2017; 12(8):e0183357.
Booiman T, Wit FW, Girigorie AF, Maurer I, De Francesco D, Sabin CA, Harskamp AM, Prins M, Franceschi C, Deeks SG, Winston A, Reiss P, Kootstra NA, Co-morBidity in Relation to Aids (COBRA) Collaboration. PMID: 28806406; PMCID: PMC5555623.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals. Pathog Immun. 2017; 2(3):310-334.
Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H. PMID: 28936485; PMCID: PMC5604865.
View in:
PubMed Mentions:
4
-
HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication. J Infect Dis. 2017 07 01; 216(1):72-81.
Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP. PMID: 28498985; PMCID: PMC5853429.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
-
Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis. Circ Cardiovasc Imaging. 2017 Jul; 10(7).
Phan BAP, Weigel B, Ma Y, Scherzer R, Li D, Hur S, Kalapus SC, Deeks S, Hsue P. PMID: 28674084; PMCID: PMC5516666.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansPHPublic Health
-
Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers. J Virol. 2017 07 15; 91(14).
Buranapraditkun S, Pissani F, Teigler JE, Schultz BT, Alter G, Marovich M, Robb ML, Eller MA, Martin J, Deeks S, Michael NL, Streeck H. PMID: 28468877; PMCID: PMC5487582.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Ultrarapid Measurement of Diagnostic Antibodies by Magnetic Capture of Immune Complexes. Sci Rep. 2017 06 19; 7(1):3818.
Burbelo PD, Gunti S, Keller JM, Morse CG, Deeks SG, Lionakis MS, Kapoor A, Li Q, Cohen JI, Notkins AL, Alevizos I. PMID: 28630417; PMCID: PMC5476601.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
-
Signature of the Sleeper Cell: A Biomarker of HIV Latency Revealed. Trends Immunol. 2017 07; 38(7):457-458.
Pillai SK, Deeks SG. PMID: 28511815; PMCID: PMC6091624.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Cell Host Microbe. 2017 May 10; 21(5):569-579.e6.
Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. PMID: 28494238; PMCID: PMC5490666.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
-
High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay. EBioMedicine. 2017 Jun; 20:217-229.
Yucha RW, Hobbs KS, Hanhauser E, Hogan LE, Nieves W, Ozen MO, Inci F, York V, Gibson EA, Thanh C, Shafiee H, El Assal R, Kiselinova M, Robles YP, Bae H, Leadabrand KS, Wang S, Deeks SG, Kuritzkes DR, Demirci U, Henrich TJ. PMID: 28529033; PMCID: PMC5478213.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2017 May; 13(5):e1006368.
Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Wook-Chun T, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 28467485; PMCID: PMC5415081.
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PubMed Mentions: Fields:
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Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression. AIDS Res Hum Retroviruses. 2017 07; 33(7):658-667.
Rutishauser RL, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht FM, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM. PMID: 28335609; PMCID: PMC5512309.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCellsPHPublic Health
-
Correction: p16INK4a Expression and Immunologic Aging in Chronic HIV Infection. PLoS One. 2017; 12(4):e0176509.
Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Passero LFD, Hunt PW, Deeks SG, Nixon DF, SenGupta D. PMID: 28426830; PMCID: PMC5398691.
View in:
PubMed Mentions:
1 Fields:
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T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response. JCI Insight. 2017 Apr 20; 2(8).
Knox JJ, Buggert M, Kardava L, Seaton KE, Eller MA, Canaday DH, Robb ML, Ostrowski MA, Deeks SG, Slifka MK, Tomaras GD, Moir S, Moody MA, Betts MR. PMID: 28422752; PMCID: PMC5396521.
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PubMed Mentions:
99 Fields:
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A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads. Virology. 2017 07; 507:135-139.
Charlins P, Schmitt K, Remling-Mulder L, Hogan LE, Hanhauser E, Hobbs KS, Hecht F, Deeks SG, Henrich TJ, Akkina R. PMID: 28432928; PMCID: PMC5901664.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Comparison of dynamic monitoring strategies based on CD4 cell counts in virally suppressed, HIV-positive individuals on combination antiretroviral therapy in high-income countries: a prospective, observational study. Lancet HIV. 2017 06; 4(6):e251-e259.
Caniglia EC, Cain LE, Sabin CA, Robins JM, Logan R, Abgrall S, Mugavero MJ, Hernández-Díaz S, Meyer L, Seng R, Drozd DR, Seage GR, Bonnet F, Dabis F, Moore RD, Reiss P, van Sighem A, Mathews WC, Del Amo J, Moreno S, Deeks SG, Muga R, Boswell SL, Ferrer E, Eron JJ, Napravnik S, Jose S, Phillips A, Justice AC, Tate JP, Gill J, Pacheco A, Veloso VG, Bucher HC, Egger M, Furrer H, Porter K, Touloumi G, Crane H, Miro JM, Sterne JA, Costagliola D, Saag M, Hernán MA, HIV-CAUSAL Collaboration, Centers for AIDS Research Network of Integrated Clinical Systems. PMID: 28411091; PMCID: PMC5492888.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy. J Infect Dis. 2017 03 15; 215(6):911-919.
Khoury G, Fromentin R, Solomon A, Hartogensis W, Killian M, Hoh R, Somsouk M, Hunt PW, Girling V, Sinclair E, Bacchetti P, Anderson JL, Hecht FM, Deeks SG, Cameron PU, Chomont N, Lewin SR. PMID: 28453847; PMCID: PMC5407052.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
-
Measuring the Size of the Latent Human Immunodeficiency Virus Reservoir: The Present and Future of Evaluating Eradication Strategies. J Infect Dis. 2017 03 15; 215(suppl_3):S134-S141.
Henrich TJ, Deeks SG, Pillai SK. PMID: 28520968; PMCID: PMC5410981.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression. J Virol. 2017 03 15; 91(6).
Jacobs ES, Keating SM, Abdel-Mohsen M, Gibb SL, Heitman JW, Inglis HC, Martin JN, Zhang J, Kaidarova Z, Deng X, Wu S, Anastos K, Crystal H, Villacres MC, Young M, Greenblatt RM, Landay AL, Gange SJ, Deeks SG, Golub ET, Pillai SK, Norris PJ. PMID: 28053103; PMCID: PMC5331794.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Comparison of cross-sectional HIV incidence assay results from dried blood spots and plasma. PLoS One. 2017; 12(2):e0172283.
Schlusser KE, Pilcher C, Kallas EG, Santos BR, Deeks SG, Facente S, Keating SM, Busch MP, Murphy G, Welte A, Quinn T, Eshleman SH, Laeyendecker O. PMID: 28231277; PMCID: PMC5322916.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection. JAMA Cardiol. 2017 02 01; 2(2):163-171.
Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY. PMID: 27926762; PMCID: PMC5310978.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
Mucosal Microbes Mitigate Maladies. Immunity. 2017 01 17; 46(1):1-3.
Vujkovic-Cvijin I, Deeks SG. PMID: 28099858.
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PubMed Mentions: Fields:
Translation:
Humans
-
Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017 01 13; 7:40354.
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC. PMID: 28084312; PMCID: PMC5233961.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
-
Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV. J Am Heart Assoc. 2016 12 20; 5(12).
Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue PY. PMID: 27998918; PMCID: PMC5210441.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
-
The interferon paradox: can inhibiting an antiviral mechanism advance an HIV cure? J Clin Invest. 2017 01 03; 127(1):103-105.
Deeks SG, Odorizzi PM, Sekaly RP. PMID: 27941242; PMCID: PMC5199692.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
-
Reverse geroscience: how does exposure to early diseases accelerate the age-related decline in health? Ann N Y Acad Sci. 2016 12; 1386(1):30-44.
Kohanski RA, Deeks SG, Gravekamp C, Halter JB, High K, Hurria A, Fuldner R, Green P, Huebner R, Macchiarini F, Sierra F. PMID: 27907230.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Using observational data to emulate a randomized trial of dynamic treatment-switching strategies: an application to antiretroviral therapy. Int J Epidemiol. 2016 12 01; 45(6):2038-2049.
Cain LE, Saag MS, Petersen M, May MT, Ingle SM, Logan R, Robins JM, Abgrall S, Shepherd BE, Deeks SG, John Gill M, Touloumi G, Vourli G, Dabis F, Vandenhende MA, Reiss P, van Sighem A, Samji H, Hogg RS, Rybniker J, Sabin CA, Jose S, Del Amo J, Moreno S, Rodríguez B, Cozzi-Lepri A, Boswell SL, Stephan C, Pérez-Hoyos S, Jarrin I, Guest JL, D'Arminio Monforte A, Antinori A, Moore R, Campbell CN, Casabona J, Meyer L, Seng R, Phillips AN, Bucher HC, Egger M, Mugavero MJ, Haubrich R, Geng EH, Olson A, Eron JJ, Napravnik S, Kitahata MM, Van Rompaey SE, Teira R, Justice AC, Tate JP, Costagliola D, Sterne JA, Hernán MA, Antiretroviral Therapy Cohort Collaboration, the Centers for AIDS Research Network of Integrated Cli. PMID: 26721599; PMCID: PMC5841611.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
p16INK4a Expression and Immunologic Aging in Chronic HIV Infection. PLoS One. 2016; 11(11):e0166759.
Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Passero LFD, Hunt PW, Deeks SG, Nixon DF, SenGupta D. PMID: 27861555; PMCID: PMC5115792.
View in:
PubMed Mentions:
9 Fields:
-
Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Mucosal Immunol. 2017 07; 10(4):1008-1020.
Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. PMID: 27827375; PMCID: PMC5423867.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
-
Psoriasis risk SNPs and their association with HIV-1 control. Hum Immunol. 2017 Feb; 78(2):179-184.
Nititham J, Gupta R, Zeng X, Hartogensis W, Nixon DF, Deeks SG, Hecht FM, Liao W. PMID: 27810495; PMCID: PMC5253078.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
High-Sequence Diversity and Rapid Virus Turnover Contribute to Higher Rates of Coreceptor Switching in Treatment-Experienced Subjects with HIV-1 Viremia. AIDS Res Hum Retroviruses. 2017 03; 33(3):234-245.
Nedellec R, Herbeck JT, Hunt PW, Deeks SG, Mullins JI, Anton ED, Reeves JD, Mosier DE. PMID: 27604829; PMCID: PMC5333564.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Ongoing Clinical Trials of Human Immunodeficiency Virus Latency-Reversing and Immunomodulatory Agents. Open Forum Infect Dis. 2016 Oct; 3(4):ofw189.
Delagrèverie HM, Delaugerre C, Lewin SR, Deeks SG, Li JZ. PMID: 27757411; PMCID: PMC5066458.
View in:
PubMed Mentions:
49
-
New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy. Retrovirology. 2016 08 24; 13(1):59.
Wacleche VS, Goulet JP, Gosselin A, Monteiro P, Soudeyns H, Fromentin R, Jenabian MA, Vartanian S, Deeks SG, Chomont N, Routy JP, Ancuta P. PMID: 27553844; PMCID: PMC4995622.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansCells
-
Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy. AIDS. 2016 08 24; 30(13):2065-74.
Hsu DC, Ma YF, Hur S, Li D, Rupert A, Scherzer R, Kalapus SC, Deeks S, Sereti I, Hsue PY. PMID: 27177313; PMCID: PMC5586221.
View in:
PubMed Mentions:
50 Fields:
Translation:
Humans
-
HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects. PLoS One. 2016; 11(8):e0160341.
Gach JS, Gorlani A, Dotsey EY, Becerra JC, Anderson CT, Berzins B, Felgner PL, Forthal DN, Deeks SG, Wilkin TJ, Casazza JP, Koup RA, Katlama C, Autran B, Murphy RL, Achenbach CJ. PMID: 27500639; PMCID: PMC4976892.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCellsCTClinical Trials
-
Defective proviruses rapidly accumulate during acute HIV-1 infection. Nat Med. 2016 09; 22(9):1043-9.
Bruner KM, Murray AJ, Pollack RA, Soliman MG, Laskey SB, Capoferri AA, Lai J, Strain MC, Lada SM, Hoh R, Ho YC, Richman DD, Deeks SG, Siliciano JD, Siliciano RF. PMID: 27500724; PMCID: PMC5014606.
View in:
PubMed Mentions:
431 Fields:
Translation:
HumansCells
-
The Benefits of Early Antiretroviral Therapy for HIV Infection: How Early is Early Enough? EBioMedicine. 2016 Sep; 11:7-8.
Lee SA, Deeks SG. PMID: 27515690; PMCID: PMC5049928.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy. PLoS One. 2016; 11(8):e0160192.
Lee SA, Bacchetti P, Chomont N, Fromentin R, Lewin SR, O'Doherty U, Palmer S, Richman DD, Siliciano JD, Yukl SA, Deeks SG, Burbelo PD. PMID: 27483366; PMCID: PMC4970722.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Multiple Origins of Virus Persistence during Natural Control of HIV Infection. Cell. 2016 Aug 11; 166(4):1004-1015.
Boritz EA, Darko S, Swaszek L, Wolf G, Wells D, Wu X, Henry AR, Laboune F, Hu J, Ambrozak D, Hughes MS, Hoh R, Casazza JP, Vostal A, Bunis D, Nganou-Makamdop K, Lee JS, Migueles SA, Koup RA, Connors M, Moir S, Schacker T, Maldarelli F, Hughes SH, Deeks SG, Douek DC. PMID: 27453467; PMCID: PMC4983216.
View in:
PubMed Mentions:
112 Fields:
Translation:
HumansCells
-
CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART. PLoS Pathog. 2016 07; 12(7):e1005761.
Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, Chomont N. PMID: 27415008; PMCID: PMC4944956.
View in:
PubMed Mentions:
245 Fields:
Translation:
HumansCells
-
International AIDS Society global scientific strategy: towards an HIV cure 2016. Nat Med. 2016 08; 22(8):839-50.
Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, Barre-Sinoussi F, International AIDS Society Towards a Cure Working Group, Alter G, Auerbach J, Autran B, Barouch DH, Behrens G, Cavazzana M, Chen Z, Cohen ÉA, Corbelli GM, Eholié S, Eyal N, Fidler S, Garcia L, Grossman C, Henderson G, Henrich TJ, Jefferys R, Kiem HP, McCune J, Moodley K, Newman PA, Nijhuis M, Nsubuga MS, Ott M, Palmer S, Richman D, Saez-Cirion A, Sharp M, Siliciano J, Silvestri G, Singh J, Spire B, Taylor J, Tolstrup M, Valente S, van Lunzen J, Walensky R, Wilson I, Zack J. PMID: 27400264; PMCID: PMC5322797.
View in:
PubMed Mentions:
260 Fields:
Translation:
Humans
-
Persistent HIV-1 replication during antiretroviral therapy. Curr Opin HIV AIDS. 2016 07; 11(4):417-23.
Martinez-Picado J, Deeks SG. PMID: 27078619; PMCID: PMC4900428.
View in:
PubMed Mentions:
91 Fields:
Translation:
HumansCells
-
Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy. AIDS. 2016 06 19; 30(10):1511-20.
Khoury G, Anderson JL, Fromentin R, Hartogenesis W, Smith MZ, Bacchetti P, Hecht FM, Chomont N, Cameron PU, Deeks SG, Lewin SR. PMID: 26807971; PMCID: PMC4889535.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
-
Immunologic profiles distinguish aviremic HIV-infected adults. AIDS. 2016 06 19; 30(10):1553-62.
Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW. PMID: 26854811; PMCID: PMC5679214.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. PLoS Pathog. 2016 06; 12(6):e1005677.
Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK. PMID: 27253379; PMCID: PMC4890776.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
-
When to Monitor CD4 Cell Count and HIV RNA to Reduce Mortality and AIDS-Defining Illness in Virologically Suppressed HIV-Positive Persons on Antiretroviral Therapy in High-Income Countries: A Prospective Observational Study. J Acquir Immune Defic Syndr. 2016 Jun 01; 72(2):214-21.
Caniglia EC, Sabin C, Robins JM, Logan R, Cain LE, Abgrall S, Mugavero MJ, Hernandez-Diaz S, Meyer L, Seng R, Drozd DR, Seage GR, Bonnet F, Dabis F, Moore RR, Reiss P, van Sighem A, Mathews WC, Del Amo J, Moreno S, Deeks SG, Muga R, Boswell SL, Ferrer E, Eron JJ, Napravnik S, Jose S, Phillips A, Olson A, Justice AC, Tate JP, Bucher HC, Egger M, Touloumi G, Sterne JA, Costagliola D, Saag M, Hernán MA, Center for AIDS Research Network of Integrated Clinical Systems and the HIV-CAUSAL Collaboration. PMID: 26895294; PMCID: PMC4866894.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People? J Acquir Immune Defic Syndr. 2016 06 01; 72(2):206-213.
So-Armah KA, Tate JP, Chang CH, Butt AA, Gerschenson M, Gibert CL, Leaf D, Rimland D, Rodriguez-Barradas MC, Budoff MJ, Samet JH, Kuller LH, Deeks SG, Crothers K, Tracy RP, Crane HM, Sajadi MM, Tindle HA, Justice AC, Freiberg MS, VACS Project Team. PMID: 27824677; PMCID: PMC4867134.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
-
Relevance of Interleukin-6 and D-Dimer for Serious Non-AIDS Morbidity and Death among HIV-Positive Adults on Suppressive Antiretroviral Therapy. PLoS One. 2016; 11(5):e0155100.
Grund B, Baker JV, Deeks SG, Wolfson J, Wentworth D, Cozzi-Lepri A, Cohen CJ, Phillips A, Lundgren JD, Neaton JD, INSIGHT SMART/ESPRIT/SILCAAT Study Group. PMID: 27171281; PMCID: PMC4865234.
View in:
PubMed Mentions:
92 Fields:
Translation:
Humans
-
Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers. AIDS Res Hum Retroviruses. 2016 08; 32(8):791-800.
Ganesh A, Lemongello D, Lee E, Peterson J, McLaughlin BE, Ferre AL, Gillespie GM, Fuchs D, Deeks SG, Hunt PW, Price RW, Spudich SS, Shacklett BL. PMID: 27019338; PMCID: PMC4971411.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". J Am Heart Assoc. 2016 04 29; 5(5).
Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY. PMID: 27130349; PMCID: PMC4889164.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment. J Infect Dis. 2016 07 15; 214(2):216-25.
Cobos Jiménez V, Wit FW, Joerink M, Maurer I, Harskamp AM, Schouten J, Prins M, van Leeuwen EM, Booiman T, Deeks SG, Reiss P, Kootstra NA, AGEhIV Study Group. PMID: 27073222; PMCID: PMC8445638.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansCells
-
Identifying Key Drivers of the Impact of an HIV Cure Intervention in Sub-Saharan Africa. J Infect Dis. 2016 07 01; 214(1):73-9.
Phillips AN, Cambiano V, Revill P, Nakagawa F, Lundgren JD, Bansi-Matharu L, Mabugu T, Sculpher M, Garnett G, Staprans S, Becker S, Murungu J, Lewin SR, Deeks SG, Hallett TB. PMID: 27034345; PMCID: PMC4907418.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2016 Mar; 12(3):e1005540.
Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 27015639; PMCID: PMC4807777.
View in:
PubMed Mentions:
6 Fields:
-
Post-Treatment Controllers: Role in HIV "Cure" Research. Curr HIV/AIDS Rep. 2016 Feb; 13(1):1-9.
Cockerham LR, Hatano H, Deeks SG. PMID: 26781112.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2016 Jan; 12(1):e1005381.
Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Wook-Chun T, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. PMID: 26795282; PMCID: PMC4721954.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection. PLoS Pathog. 2016 Jan; 12(1):e1005349.
Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC. PMID: 26741490; PMCID: PMC4704737.
View in:
PubMed Mentions:
174 Fields:
Translation:
HumansAnimalsCells
-
Cerebral vasoreactivity is impaired in treated, virally suppressed HIV-infected individuals. AIDS. 2016 Jan 02; 30(1):45-55.
Chow FC, Boscardin WJ, Mills C, Ko N, Carroll C, Price RW, Deeks S, Sorond FA, Hsue PY. PMID: 26372478; PMCID: PMC4703496.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
HIV reservoirs: what, where and how to target them. Nat Rev Microbiol. 2016 01; 14(1):55-60.
Churchill MJ, Deeks SG, Margolis DM, Siliciano RF, Swanstrom R. PMID: 26616417.
View in:
PubMed Mentions:
165 Fields:
Translation:
HumansCells
-
Lack of Evidence for Molecular Mimicry in HIV-Infected Subjects. PLoS One. 2015; 10(11):e0127662.
Burbelo PD, Klimavicz JS, Deeks SG, Kovacs JA, Ragheb JA. PMID: 26599070; PMCID: PMC4657959.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study. Lancet HIV. 2015 Dec; 2(12):e520-9.
Elliott JH, McMahon JH, Chang CC, Lee SA, Hartogensis W, Bumpus N, Savic R, Roney J, Hoh R, Solomon A, Piatak M, Gorelick RJ, Lifson J, Bacchetti P, Deeks SG, Lewin SR. PMID: 26614966; PMCID: PMC5108570.
View in:
PubMed Mentions:
144 Fields:
Translation:
HumansCellsCTClinical Trials
-
Virome analysis of antiretroviral-treated HIV patients shows no correlation between T-cell activation and anelloviruses levels. J Clin Virol. 2015 Nov; 72:106-13.
Li L, Deng X, Da Costa AC, Bruhn R, Deeks SG, Delwart E. PMID: 26479202; PMCID: PMC4697764.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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HIV infection. Nat Rev Dis Primers. 2015 10 01; 1:15035.
Deeks SG, Overbaugh J, Phillips A, Buchbinder S. PMID: 27188527.
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PubMed Mentions:
210 Fields:
Translation:
HumansCells
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The HIV Cure Research Agenda: The Role of Mathematical Modelling and Cost-Effectiveness Analysis. J Virus Erad. 2015; 1(4):245-249.
Freedberg KA, Possas C, Deeks S, Ross AL, Rosettie KL, Di Mascio M, Collins C, Walensky RP, Yazdanpanah Y. PMID: 26878073; PMCID: PMC4748959.
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PubMed Mentions:
6
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Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):E4762-71.
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. PMID: 26307764; PMCID: PMC4553789.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals. JACC Heart Fail. 2015 Aug; 3(8):591-9.
Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY. PMID: 26164679; PMCID: PMC4529774.
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PubMed Mentions:
44 Fields:
Translation:
Humans
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Mitral Annular and Coronary Artery Calcification Are Associated with Mortality in HIV-Infected Individuals. PLoS One. 2015; 10(7):e0130592.
Lange DC, Glidden D, Secemsky EA, Ordovas K, Deeks SG, Martin JN, Bolger AF, Hsue PY. PMID: 26132465; PMCID: PMC4488486.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals. EBioMedicine. 2015 Aug; 2(8):874-83.
Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJ, Miller MD, Hazuda DJ, Deeks SG, Sékaly RP, Chomont N. PMID: 26425694; PMCID: PMC4563128.
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PubMed Mentions:
172 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
100 Fields:
Translation:
Humans
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Viremic control and viral coreceptor usage in two HIV-1-infected persons homozygous for CCR5 Δ32. AIDS. 2015 May 15; 29(8):867-76.
Henrich TJ, Hanhauser E, Hu Z, Stellbrink HJ, Noah C, Martin JN, Deeks SG, Kuritzkes DR, Pereyra F. PMID: 25730507; PMCID: PMC4473772.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Viremic HIV Controllers Exhibit High Plasmacytoid Dendritic Cell-Reactive Opsonophagocytic IgG Antibody Responses against HIV-1 p24 Associated with Greater Antibody Isotype Diversification. J Immunol. 2015 Jun 01; 194(11):5320-8.
Tjiam MC, Taylor JP, Morshidi MA, Sariputra L, Burrows S, Martin JN, Deeks SG, Tan DB, Lee S, Fernandez S, French MA. PMID: 25911748; PMCID: PMC4492937.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Summary of the National Advisory Committee on Immunization's Update on the recommended human papillomavirus (HPV) vaccine immunization schedule. Can Commun Dis Rep. 2015 Apr 20; 41(Suppl 3):11-13.
Ismail S, Deeks S, National Advisory Committee on Immunization. PMID: 29769961; PMCID: PMC5868570.
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PubMed Mentions:
14 Fields:
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Clinical and demographic factors associated with low viral load in early untreated HIV infection in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial. HIV Med. 2015 Apr; 16 Suppl 1:37-45.
Law MG, Achhra A, Deeks SG, Gazzard B, Migueles SA, Novak RM, Ristola M, International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) START Study Group. PMID: 25711322; PMCID: PMC4341944.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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HIV eradication symposium: will the brain be left behind? J Neurovirol. 2015 Jun; 21(3):322-34.
Brew BJ, Robertson K, Wright EJ, Churchill M, Crowe SM, Cysique LA, Deeks S, Garcia JV, Gelman B, Gray LR, Johnson T, Joseph J, Margolis DM, Mankowski JL, Spencer B. PMID: 25750070; PMCID: PMC4432099.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy. J Infect Dis. 2015 Aug 15; 212(4):596-607.
von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, Boritz E, Deeks SG, Hecht FM, Palmer S. PMID: 25712966; PMCID: PMC4539896.
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PubMed Mentions:
98 Fields:
Translation:
HumansCells
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Select host restriction factors are associated with HIV persistence during antiretroviral therapy. AIDS. 2015 Feb 20; 29(4):411-20.
Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK. PMID: 25602681; PMCID: PMC4385712.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Effect of therapeutic intensification followed by HIV DNA prime and rAd5 boost vaccination on HIV-specific immunity and HIV reservoir (EraMune 02): a multicentre randomised clinical trial. Lancet HIV. 2015 Mar; 2(3):e82-91.
Achenbach CJ, Assoumou L, Deeks SG, Wilkin TJ, Berzins B, Casazza JP, Lambert-Niclot S, Koup RA, Costagliola D, Calvez V, Katlama C, Autran B, Murphy RL, EraMune 02 study team. PMID: 26424549; PMCID: PMC6322849.
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CD4/CD8 ratio: an emerging biomarker for HIV. Lancet HIV. 2015 Mar; 2(3):e76-7.
Serrano-Villar S, Deeks SG. PMID: 26424546.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa. Int J Epidemiol. 2015 Feb; 44(1):251-63.
Geng EH, Neilands TB, Thièbaut R, Bwana MB, Nash D, Moore RD, Wood R, Zannou DM, Althoff KN, Lim PL, Nachega JB, Easterbrook PJ, Kambugu A, Little F, Nakigozi G, Nakanjako D, Kiggundu V, Ki Li PC, Bangsberg DR, Fox MP, Prozesky H, Hunt PW, Davies MA, Reynolds SJ, Egger M, Yiannoutsos CT, Vittinghoff EV, Deeks SG, Martin JN. PMID: 25859596; PMCID: PMC4339766.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Soluble T cell immunoglobulin mucin domain 3 is shed from CD8+ T cells by the sheddase ADAM10, is increased in plasma during untreated HIV infection, and correlates with HIV disease progression. J Virol. 2015 Apr; 89(7):3723-36.
Clayton KL, Douglas-Vail MB, Nur-ur Rahman AK, Medcalf KE, Xie IY, Chew GM, Tandon R, Lanteri MC, Norris PJ, Deeks SG, Ndhlovu LC, Ostrowski MA. PMID: 25609823; PMCID: PMC4403393.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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CD8+ T-cells count in acute myocardial infarction in HIV disease in a predominantly male cohort. Biomed Res Int. 2015; 2015:246870.
Badejo OA, Chang CC, So-Armah KA, Tracy RP, Baker JV, Rimland D, Butt AA, Gordon AJ, Rinaldo CR, Kraemer K, Samet JH, Tindle HA, Goetz MB, Rodriguez-Barradas MC, Bedimo R, Gibert CL, Leaf DA, Kuller LH, Deeks SG, Justice AC, Freiberg MS. PMID: 25688354; PMCID: PMC4320893.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature. 2015 Jan 15; 517(7534):381-5.
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H, Margolick JB, Gurer C, Murphy AJ, Valenzuela DM, Yancopoulos GD, Deeks SG, Strowig T, Kumar P, Siliciano JD, Salzberg SL, Flavell RA, Shan L, Siliciano RF. PMID: 25561180; PMCID: PMC4406054.
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PubMed Mentions:
322 Fields:
Translation:
HumansAnimalsCells
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Gut epithelial barrier and systemic inflammation during chronic HIV infection. AIDS. 2015 Jan 02; 29(1):43-51.
Somsouk M, Estes JD, Deleage C, Dunham RM, Albright R, Inadomi JM, Martin JN, Deeks SG, McCune JM, Hunt PW. PMID: 25387317; PMCID: PMC4444362.
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PubMed Mentions:
110 Fields:
Translation:
HumansCells
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The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial. PLoS One. 2014; 9(12):e116306.
Somsouk M, Dunham RM, Cohen M, Albright R, Abdel-Mohsen M, Liegler T, Lifson J, Piatak M, Gorelick R, Huang Y, Wu Y, Hsue PY, Martin JN, Deeks SG, McCune JM, Hunt PW. PMID: 25545673; PMCID: PMC4283685.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men-San Francisco, California. J Infect Dis. 2015 Jun 01; 211(11):1757-60.
Hollingsworth TD, Pilcher CD, Hecht FM, Deeks SG, Fraser C. PMID: 25542958; PMCID: PMC4425938.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy. PLoS Pathog. 2014 Oct; 10(10):e1004473.
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, Smith MZ, Spelman T, McMahon J, Velayudham P, Brown G, Roney J, Watson J, Prince MH, Hoy JF, Chomont N, Fromentin R, Procopio FA, Zeidan J, Palmer S, Odevall L, Johnstone RW, Martin BP, Sinclair E, Deeks SG, Hazuda DJ, Cameron PU, Sékaly RP, Lewin SR. PMID: 25393648; PMCID: PMC4231123.
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PubMed Mentions:
325 Fields:
Translation:
HumansCellsCTClinical Trials
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Towards an HIV cure. J Int AIDS Soc. 2014; 17(4 Suppl 3):19479.
Deeks S. PMID: 25393988; PMCID: PMC4224933.
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PubMed Mentions:
6 Fields:
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Lymphoid fibrosis occurs in long-term nonprogressors and persists with antiretroviral therapy but may be reversible with curative interventions. J Infect Dis. 2015 Apr 01; 211(7):1068-75.
Sanchez JL, Hunt PW, Reilly CS, Hatano H, Beilman GJ, Khoruts A, Jasurda JS, Somsouk M, Thorkelson A, Russ S, Anderson J, Deeks SG, Schacker TW. PMID: 25344521; PMCID: PMC4416122.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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HIV Prevention and Treatment Fields Join Forces. EBioMedicine. 2014 Nov; 1(1):4-5.
Deeks SG, Siliciano R. PMID: 26137503; PMCID: PMC4457402.
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PubMed Mentions:
1 Fields:
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CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. PLoS One. 2014; 9(10):e110731.
Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. PMID: 25340755; PMCID: PMC4207702.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Biomarker reveals HIV's hidden reservoir. Elife. 2014 Oct 16; 3:e04742.
Cockerham LR, Deeks SG. PMID: 25321627; PMCID: PMC4199414.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The CD8⁺ memory stem T cell (T(SCM)) subset is associated with improved prognosis in chronic HIV-1 infection. J Virol. 2014 Dec; 88(23):13836-44.
Ribeiro SP, Milush JM, Cunha-Neto E, Kallas EG, Kalil J, Somsouk M, Hunt PW, Deeks SG, Nixon DF, SenGupta D. PMID: 25253339; PMCID: PMC4248986.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Delayed switch of antiretroviral therapy after virologic failure associated with elevated mortality among HIV-infected adults in Africa. AIDS. 2014 Sep 10; 28(14):2097-107.
Petersen ML, Tran L, Geng EH, Reynolds SJ, Kambugu A, Wood R, Bangsberg DR, Yiannoutsos CT, Deeks SG, Martin JN. PMID: 24977440; PMCID: PMC4317283.
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PubMed Mentions:
70 Fields:
Translation:
HumansCells
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Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals. PLoS Pathog. 2014 Aug; 10(8):e1004345.
Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, Lederman MM, Paiardini M, Kirchhoff F, Brenchley JM, Hunt PW, Silvestri G. PMID: 25167059; PMCID: PMC4148445.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Levels of circulating myeloid subpopulations and of heme oxygenase-1 do not predict CD4(+) T cell recovery after the initiation of antiretroviral therapy for HIV disease. AIDS Res Ther. 2014; 11:27.
Seu L, Ortiz GM, Burt TD, Deeks SG, Martin JN, McCune JM. PMID: 25180041; PMCID: PMC4150425.
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PubMed Mentions:
2 Fields:
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Markers of inflammation and activation of coagulation are associated with anaemia in antiretroviral-treated HIV disease. AIDS. 2014 Jul 31; 28(12):1791-6.
Borges ÁH, Weitz JI, Collins G, Baker JV, Lévy Y, Davey RT, Phillips AN, Neaton JD, Lundgren JD, Deeks SG, INSIGHT SILCAAT Scientific Committee. PMID: 25003720; PMCID: PMC4499102.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease. AIDS. 2014 Jul 31; 28(12):1749-58.
Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG. PMID: 24871455; PMCID: PMC4206412.
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PubMed Mentions:
69 Fields:
Translation:
HumansCells
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Antiretroviral therapy: stubborn limitations persist. Lancet. 2014 Jul 19; 384(9939):214-6.
Deeks SG, Hunt PW. PMID: 25042221.
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PubMed Mentions: Fields:
Translation:
Humans
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Towards a cure for HIV--are we making progress? Lancet. 2014 Jul 19; 384(9939):209-11.
Lewin SR, Deeks SG, Barré-Sinoussi F. PMID: 25042220.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells. J Immunol. 2014 Aug 15; 193(4):1544-8.
Michaud HA, SenGupta D, de Mulder M, Deeks SG, Martin JN, Kobie JJ, Sacha JB, Nixon DF. PMID: 25024383; PMCID: PMC4120895.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Immunologic strategies for HIV-1 remission and eradication. Science. 2014 Jul 11; 345(6193):169-74.
Barouch DH, Deeks SG. PMID: 25013067; PMCID: PMC4096716.
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PubMed Mentions:
123 Fields:
Translation:
HumansCellsPHPublic Health
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Exogenous and endogenous hyaluronic acid reduces HIV infection of CD4(+) T cells. Immunol Cell Biol. 2014 Oct; 92(9):770-80.
Li P, Fujimoto K, Bourguingnon L, Yukl S, Deeks S, Wong JK. PMID: 24957217; PMCID: PMC4205896.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy. J Infect Dis. 2014 Dec 01; 210(11):1838-43.
Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK. PMID: 24935955; PMCID: PMC4271057.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers. AIDS Res Hum Retroviruses. 2014 Jul; 30(7):654-64.
Tandon R, Chew GM, Byron MM, Borrow P, Niki T, Hirashima M, Barbour JD, Norris PJ, Lanteri MC, Martin JN, Deeks SG, Ndhlovu LC. PMID: 24786365; PMCID: PMC4077009.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection. J Infect Dis. 2014 Nov 15; 210(10):1549-54.
Sandler NG, Zhang X, Bosch RJ, Funderburg NT, Choi AI, Robinson JK, Fine DM, Coombs RW, Jacobson JM, Landay AL, Douek DC, Tressler R, Read SW, Wilson CC, Deeks SG, Lederman MM, Gandhi RT, AIDS Clinical Trials Group A5296 Team. PMID: 24864123; PMCID: PMC4215074.
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PubMed Mentions:
46 Fields:
Translation:
HumansCTClinical Trials
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A closer look at hepatitis C clearance in HIV controllers: a response. AIDS. 2014 May 15; 28(8):1241-2.
Asher AK, Santos GM, Evans J, Dokubo EK, Lee TH, Martin JN, Deeks SG, Tobler LH, Busch M, Hunt PW, Page K. PMID: 25028914; PMCID: PMC4214212.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. PLoS Pathog. 2014 May; 10(5):e1004078.
Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. PMID: 24831517; PMCID: PMC4022662.
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PubMed Mentions:
307 Fields:
Translation:
HumansCells
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Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment. J Infect Dis. 2014 Oct 15; 210(8):1248-59.
Tenorio AR, Zheng Y, Bosch RJ, Krishnan S, Rodriguez B, Hunt PW, Plants J, Seth A, Wilson CC, Deeks SG, Lederman MM, Landay AL. PMID: 24795473; PMCID: PMC4192039.
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PubMed Mentions:
303 Fields:
Translation:
HumansCells
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Dependence on the CCR5 coreceptor for viral replication explains the lack of rebound of CXCR4-predicted HIV variants in the Berlin patient. Clin Infect Dis. 2014 Aug 15; 59(4):596-600.
Symons J, Vandekerckhove L, Hütter G, Wensing AM, van Ham PM, Deeks SG, Nijhuis M. PMID: 24759824; PMCID: PMC4990826.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Lymphoma immune reconstitution inflammatory syndrome in the center for AIDS research network of integrated clinical systems cohort. Clin Infect Dis. 2014 Jul 15; 59(2):279-86.
Gopal S, Patel MR, Achenbach CJ, Yanik EL, Cole SR, Napravnik S, Burkholder GA, Mathews WC, Rodriguez B, Deeks SG, Mayer KH, Moore RD, Kitahata MM, Richards KL, Eron JJ. PMID: 24755860; PMCID: PMC4102912.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection. J Infect Dis. 2014 Oct 15; 210(8):1228-38.
Hunt PW, Sinclair E, Rodriguez B, Shive C, Clagett B, Funderburg N, Robinson J, Huang Y, Epling L, Martin JN, Deeks SG, Meinert CL, Van Natta ML, Jabs DA, Lederman MM. PMID: 24755434; PMCID: PMC4192038.
View in:
PubMed Mentions:
289 Fields:
Translation:
HumansCells
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Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs. PLoS One. 2014; 9(4):e92934.
Siewe B, Wallace J, Rygielski S, Stapleton JT, Martin J, Deeks SG, Landay A. PMID: 24739950; PMCID: PMC3989168.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Reduction of HIV persistence following transplantation in HIV-infected kidney transplant recipients. Am J Transplant. 2014 May; 14(5):1136-41.
Stock PG, Barin B, Hatano H, Rogers RL, Roland ME, Lee TH, Busch M, Deeks SG, for Solid Organ Transplantation in HIV Study Investigators. PMID: 24698537; PMCID: PMC4012326.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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LILRB2 interaction with HLA class I correlates with control of HIV-1 infection. PLoS Genet. 2014 Mar; 10(3):e1004196.
Bashirova AA, Martin-Gayo E, Jones DC, Qi Y, Apps R, Gao X, Burke PS, Taylor CJ, Rogich J, Wolinsky S, Bream JH, Duggal P, Hussain S, Martinson J, Weintrob A, Kirk GD, Fellay J, Buchbinder SP, Goedert JJ, Deeks SG, Pereyra F, Trowsdale J, Lichterfeld M, Telenti A, Walker BD, Allen RL, Carrington M, Yu XG. PMID: 24603468; PMCID: PMC3945438.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
-
The kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy. J Infect Dis. 2014 Aug 01; 210(3):383-91.
Byakwaga H, Boum Y, Huang Y, Muzoora C, Kembabazi A, Weiser SD, Bennett J, Cao H, Haberer JE, Deeks SG, Bangsberg DR, McCune JM, Martin JN, Hunt PW. PMID: 24585899; PMCID: PMC4148610.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansCells
-
Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection. J Infect Dis. 2014 Aug 01; 210(3):374-82.
Lee SA, Sinclair E, Jain V, Huang Y, Epling L, Van Natta M, Meinert CL, Martin JN, McCune JM, Deeks SG, Lederman MM, Hecht FM, Hunt PW. PMID: 24585893; PMCID: PMC4110459.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
-
Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging. PLoS One. 2014; 9(2):e89444.
Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW. PMID: 24586783; PMCID: PMC3937334.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
-
Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection. AIDS. 2014 Feb 20; 28(4):511-9.
Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. PMID: 24469026; PMCID: PMC4149286.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
-
Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints. J Virol. 2014 May; 88(9):4668-78.
Payne RP, Branch S, Kløverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, Hunter E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ. PMID: 24501417; PMCID: PMC3993828.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Discordance between peripheral and colonic markers of inflammation during suppressive ART. J Acquir Immune Defic Syndr. 2014 Feb 01; 65(2):133-41.
Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM. PMID: 24121758; PMCID: PMC3997573.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection. Retrovirology. 2014 Jan 28; 11:10.
Michaud HA, de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF. PMID: 24472118; PMCID: PMC3907665.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells. AIDS. 2014 Jan 28; 28(3):439-42.
Yukl SA, Sinclair E, Somsouk M, Hunt PW, Epling L, Killian M, Girling V, Li P, Havlir DV, Deeks SG, Wong JK, Hatano H. PMID: 24322272; PMCID: PMC4130176.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Targeting host nucleotide biosynthesis with resveratrol inhibits emtricitabine-resistant HIV-1. AIDS. 2014 Jan 28; 28(3):317-23.
Heredia A, Davis C, Amin MN, Le NM, Wainberg MA, Oliveira M, Deeks SG, Wang LX, Redfield RR. PMID: 24326355; PMCID: PMC4469130.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Composition and function of T cell subpopulations are slow to change despite effective antiretroviral treatment of HIV disease. PLoS One. 2014; 9(1):e85613.
Emu B, Moretto WJ, Hoh R, Krone M, Martin JN, Nixon DF, Deeks SG, McCune JM. PMID: 24465619; PMCID: PMC3897457.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration. PLoS One. 2014; 9(1):e85516.
Boufassa F, Lechenadec J, Meyer L, Costagliola D, Hunt PW, Pereyra F, Deeks S, Pancino G, Taulera O, Lichterfeld M, Delobel P, Saez-Cirion A, Lambotte O, ANRS CO18 HIV Controllers Cohort, Cascade Collaboration in Eurocoord, SCOPE Cohort, International HIV Controllers Study. PMID: 24465584; PMCID: PMC3894966.
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PubMed Mentions:
19 Fields:
Translation:
Humans
-
Reply to Karch et al. J Infect Dis. 2014 Jul 01; 210(1):159-60.
Hatano H, Bacchetti P, Hsue PY, Deeks SG. PMID: 24421253; PMCID: PMC4161999.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection. PLoS One. 2013; 8(12):e84091.
Seu L, Ortiz GM, Epling L, Sinclair E, Swainson LA, Bajpai UD, Huang Y, Deeks SG, Hunt PW, Martin JN, McCune JM. PMID: 24391889; PMCID: PMC3877182.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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CD56negCD16⁺ NK cells are activated mature NK cells with impaired effector function during HIV-1 infection. Retrovirology. 2013 Dec 18; 10:158.
Milush JM, López-Vergès S, York VA, Deeks SG, Martin JN, Hecht FM, Lanier LL, Nixon DF. PMID: 24351015; PMCID: PMC3892122.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCells
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A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy. Clin Infect Dis. 2014 Mar; 58(6):883-90.
Spivak AM, Andrade A, Eisele E, Hoh R, Bacchetti P, Bumpus NN, Emad F, Buckheit R, McCance-Katz EF, Lai J, Kennedy M, Chander G, Siliciano RF, Siliciano JD, Deeks SG. PMID: 24336828; PMCID: PMC3935499.
View in:
PubMed Mentions:
118 Fields:
Translation:
HumansCells
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HIV antibody characterization as a method to quantify reservoir size during curative interventions. J Infect Dis. 2014 May 15; 209(10):1613-7.
Burbelo PD, Bayat A, Rhodes CS, Hoh R, Martin JN, Fromentin R, Chomont N, Hütter G, Kovacs JA, Deeks SG. PMID: 24286982; PMCID: PMC3997576.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
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The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):E4987-96.
Josefsson L, von Stockenstrom S, Faria NR, Sinclair E, Bacchetti P, Killian M, Epling L, Tan A, Ho T, Lemey P, Shao W, Hunt PW, Somsouk M, Wylie W, Douek DC, Loeb L, Custer J, Hoh R, Poole L, Deeks SG, Hecht F, Palmer S. PMID: 24277811; PMCID: PMC3870728.
View in:
PubMed Mentions:
180 Fields:
Translation:
HumansCellsCTClinical Trials
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Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):20705-10.
Kulkarni S, Qi Y, O'hUigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, Carrington M. PMID: 24248364; PMCID: PMC3870724.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCellsCTClinical Trials
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Human leukocyte antigen B*57 does not fully explain hepatitis C clearance in HIV controllers. AIDS. 2013 Nov 13; 27(17):2691-6.
Asher AK, Santos GM, Evans J, Dokubo EK, Lee TH, Martin JN, Deeks SG, Tobler LH, Busch M, Hunt PW, Page K. PMID: 23939233; PMCID: PMC4125012.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
HIV: Antibodies advance the search for a cure. Nature. 2013 Nov 14; 503(7475):207-8.
Picker LJ, Deeks SG. PMID: 24172894.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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The end of AIDS: HIV infection as a chronic disease. Lancet. 2013 Nov 02; 382(9903):1525-33.
Deeks SG, Lewin SR, Havlir DV. PMID: 24152939; PMCID: PMC4058441.
View in:
PubMed Mentions:
775 Fields:
Translation:
Humans
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Effects of alpha interferon treatment on intrinsic anti-HIV-1 immunity in vivo. J Virol. 2014 Jan; 88(1):763-7.
Abdel-Mohsen M, Deng X, Liegler T, Guatelli JC, Salama MS, Ghanem Hel-D, Rauch A, Ledergerber B, Deeks SG, Günthard HF, Wong JK, Pillai SK. PMID: 24155399; PMCID: PMC3911728.
View in:
PubMed Mentions:
18 Fields:
Translation:
Cells
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Systemic effects of inflammation on health during chronic HIV infection. Immunity. 2013 Oct 17; 39(4):633-45.
Deeks SG, Tracy R, Douek DC. PMID: 24138880; PMCID: PMC4012895.
View in:
PubMed Mentions:
414 Fields:
Translation:
HumansCells
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Expression profile of host restriction factors in HIV-1 elite controllers. Retrovirology. 2013 Oct 16; 10:106.
Abdel-Mohsen M, Raposo RA, Deng X, Li M, Liegler T, Sinclair E, Salama MS, Ghanem Hel-D, Hoh R, Wong JK, David M, Nixon DF, Deeks SG, Pillai SK. PMID: 24131498; PMCID: PMC3827935.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. PLoS Pathog. 2013; 9(10):e1003691.
Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG. PMID: 24130489; PMCID: PMC3795031.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCellsCTClinical Trials
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Response: Maraviroc intensification and microbial translocation. Blood. 2013 Sep 26; 122(13):2283-4.
Hunt PW, Lederman MM, Deeks SG. PMID: 24072849.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Association of early HIV viremia with mortality after HIV-associated lymphoma. AIDS. 2013 Sep 24; 27(15):2365-73.
Gopal S, Patel MR, Yanik EL, Cole SR, Achenbach CJ, Napravnik S, Burkholder GA, Reid EG, Rodriguez B, Deeks SG, Mayer KH, Moore RD, Kitahata MM, Richards KL, Eron JJ. PMID: 23736149; PMCID: PMC3773290.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
-
Comparison of HIV DNA and RNA in gut-associated lymphoid tissue of HIV-infected controllers and noncontrollers. AIDS. 2013 Sep 10; 27(14):2255-60.
Hatano H, Somsouk M, Sinclair E, Harvill K, Gilman L, Cohen M, Hoh R, Hunt PW, Martin JN, Wong JK, Deeks SG, Yukl SA. PMID: 24157906; PMCID: PMC4143147.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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The impact of age on the prognostic capacity of CD8+ T-cell activation during suppressive antiretroviral therapy. AIDS. 2013 Aug 24; 27(13):2101-10.
Lok JJ, Hunt PW, Collier AC, Benson CA, Witt MD, Luque AE, Deeks SG, Bosch RJ. PMID: 24326304; PMCID: PMC3933027.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. J Infect Dis. 2013 Nov 01; 208(9):1436-42.
Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue PY, Richman DD, Deeks SG. PMID: 23975885; PMCID: PMC3789577.
View in:
PubMed Mentions:
100 Fields:
Translation:
HumansCells
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Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected]. PLoS One. 2013; 8(8):e71879.
Graf EH, Pace MJ, Peterson BA, Lynch LJ, Chukwulebe SB, Mexas AM, Shaheen F, Martin JN, Deeks SG, Connors M, Migueles SA, O'Doherty U. PMID: 23951263; PMCID: PMC3737195.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
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AIDS alters the commensal plasma virome. J Virol. 2013 Oct; 87(19):10912-5.
Li L, Deng X, Linsuwanon P, Bangsberg D, Bwana MB, Hunt P, Martin JN, Deeks SG, Delwart E. PMID: 23903845; PMCID: PMC3807392.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCells
-
Cortisol patterns are associated with T cell activation in HIV. PLoS One. 2013; 8(7):e63429.
Patterson S, Moran P, Epel E, Sinclair E, Kemeny ME, Deeks SG, Bacchetti P, Acree M, Epling L, Kirschbaum C, Hecht FM. PMID: 23922644; PMCID: PMC3724863.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Temporal trends in presentation and survival for HIV-associated lymphoma in the antiretroviral therapy era. J Natl Cancer Inst. 2013 Aug 21; 105(16):1221-9.
Gopal S, Patel MR, Yanik EL, Cole SR, Achenbach CJ, Napravnik S, Burkholder GA, Reid EG, Rodriguez B, Deeks SG, Mayer KH, Moore RD, Kitahata MM, Eron JJ, Richards KL. PMID: 23892362; PMCID: PMC3748003.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls. PLoS Pathog. 2013; 9(7):e1003515.
McLaren PJ, Coulonges C, Ripke S, van den Berg L, Buchbinder S, Carrington M, Cossarizza A, Dalmau J, Deeks SG, Delaneau O, De Luca A, Goedert JJ, Haas D, Herbeck JT, Kathiresan S, Kirk GD, Lambotte O, Luo M, Mallal S, van Manen D, Martinez-Picado J, Meyer L, Miro JM, Mullins JI, Obel N, O'Brien SJ, Pereyra F, Plummer FA, Poli G, Qi Y, Rucart P, Sandhu MS, Shea PR, Schuitemaker H, Theodorou I, Vannberg F, Veldink J, Walker BD, Weintrob A, Winkler CA, Wolinsky S, Telenti A, Goldstein DB, de Bakker PI, Zagury JF, Fellay J. PMID: 23935489; PMCID: PMC3723635.
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PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Immunosenescence is associated with presence of Kaposi's sarcoma in antiretroviral treated HIV infection. AIDS. 2013 Jul 17; 27(11):1735-42.
Unemori P, Leslie KS, Hunt PW, Sinclair E, Epling L, Mitsuyasu R, Effros RB, Dock J, Dollard SG, Deeks SG, Martin JN, Maurer TA. PMID: 23435301; PMCID: PMC4063793.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
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The distribution of HIV DNA and RNA in cell subsets differs in gut and blood of HIV-positive patients on ART: implications for viral persistence. J Infect Dis. 2013 Oct 15; 208(8):1212-20.
Yukl SA, Shergill AK, Ho T, Killian M, Girling V, Epling L, Li P, Wong LK, Crouch P, Deeks SG, Havlir DV, McQuaid K, Sinclair E, Wong JK. PMID: 23852128; PMCID: PMC3778964.
View in:
PubMed Mentions:
114 Fields:
Translation:
HumansCells
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Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. J Infect Dis. 2013 Oct 15; 208(8):1202-11.
Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. PMID: 23852127; PMCID: PMC3778965.
View in:
PubMed Mentions:
191 Fields:
Translation:
HumansCells
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Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism. Sci Transl Med. 2013 Jul 10; 5(193):193ra91.
Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM. PMID: 23843452; PMCID: PMC4094294.
View in:
PubMed Mentions:
374 Fields:
Translation:
HumansAnimalsCells
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Immune activation and HIV persistence: implications for curative approaches to HIV infection. Immunol Rev. 2013 Jul; 254(1):326-42.
Klatt NR, Chomont N, Douek DC, Deeks SG. PMID: 23772629; PMCID: PMC3694608.
View in:
PubMed Mentions:
227 Fields:
Translation:
HumansAnimals
-
Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control. Nat Med. 2013 Jul; 19(7):930-3.
Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, Sette A, Carrington M, Streeck H. PMID: 23793098; PMCID: PMC3974408.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog. 2013; 9(5):e1003347.
Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG. PMID: 23671416; PMCID: PMC3649997.
View in:
PubMed Mentions:
151 Fields:
Translation:
HumansCellsCTClinical Trials
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View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial. Blood. 2013 Jun 06; 121(23):4635-46.
Hunt PW, Shulman NS, Hayes TL, Dahl V, Somsouk M, Funderburg NT, McLaughlin B, Landay AL, Adeyemi O, Gilman LE, Clagett B, Rodriguez B, Martin JN, Schacker TW, Shacklett BL, Palmer S, Lederman MM, Deeks SG. PMID: 23589670; PMCID: PMC3685899.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansCells
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Influence of HLA-C expression level on HIV control. Science. 2013 Apr 05; 340(6128):87-91.
Apps R, Qi Y, Carlson JM, Chen H, Gao X, Thomas R, Yuki Y, Del Prete GQ, Goulder P, Brumme ZL, Brumme CJ, John M, Mallal S, Nelson G, Bosch R, Heckerman D, Stein JL, Soderberg KA, Moody MA, Denny TN, Zeng X, Fang J, Moffett A, Lifson JD, Goedert JJ, Buchbinder S, Kirk GD, Fellay J, McLaren P, Deeks SG, Pereyra F, Walker B, Michael NL, Weintrob A, Wolinsky S, Liao W, Carrington M. PMID: 23559252; PMCID: PMC3784322.
View in:
PubMed Mentions:
220 Fields:
Translation:
HumansCells
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Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet. 2013 Jun 15; 381(9883):2109-17.
Katlama C, Deeks SG, Autran B, Martinez-Picado J, van Lunzen J, Rouzioux C, Miller M, Vella S, Schmitz JE, Ahlers J, Richman DD, Sekaly RP. PMID: 23541541; PMCID: PMC3815451.
View in:
PubMed Mentions:
161 Fields:
Translation:
HumansCells
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Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population. AIDS. 2013 Mar 27; 27(6):973-979.
Rodger AJ, Lodwick R, Schechter M, Deeks S, Amin J, Gilson R, Paredes R, Bakowska E, Engsig FN, Phillips A, INSIGHT SMART, ESPRIT Study Groups. PMID: 23698063.
View in:
PubMed Mentions:
164 Fields:
Translation:
Humans
-
T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques. J Virol. 2013 Jun; 87(11):6073-80.
Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, Hecht FM, Ostrowski MA, Sacha JB, Nixon DF. PMID: 23536679; PMCID: PMC3648095.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. PLoS Pathog. 2013 Feb; 9(2):e1003174.
Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, Wong J, Johnston R, Siliciano RF, Richman DD, O'Doherty U, Palmer S, Deeks SG, Siliciano JD. PMID: 23459007; PMCID: PMC3573107.
View in:
PubMed Mentions:
365 Fields:
Translation:
HumansCells
-
Predictive accuracy of the Veterans Aging Cohort Study index for mortality with HIV infection: a North American cross cohort analysis. J Acquir Immune Defic Syndr. 2013 Feb 01; 62(2):149-63.
Justice AC, Modur SP, Tate JP, Althoff KN, Jacobson LP, Gebo KA, Kitahata MM, Horberg MA, Brooks JT, Buchacz K, Rourke SB, Rachlis A, Napravnik S, Eron J, Willig JH, Moore R, Kirk GD, Bosch R, Rodriguez B, Hogg RS, Thorne J, Goedert JJ, Klein M, Gill J, Deeks S, Sterling TR, Anastos K, Gange SJ, NA-ACCORD and VACS Project Teams. PMID: 23187941; PMCID: PMC3619393.
View in:
PubMed Mentions:
132 Fields:
Translation:
HumansCells
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Roadblocks to translational challenges on viral pathogenesis. Nat Med. 2013 Jan; 19(1):30-4.
Deeks S, Drosten C, Picker L, Subbarao K, Suzich J. PMID: 23296014; PMCID: PMC7095913.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Differential expression of CD96 surface molecule represents CD8⁺ T cells with dissimilar effector function during HIV-1 infection. PLoS One. 2012; 7(12):e51696.
Eriksson EM, Keh CE, Deeks SG, Martin JN, Hecht FM, Nixon DF. PMID: 23272144; PMCID: PMC3521672.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. Blood. 2013 Feb 14; 121(7):1124-35.
Leeansyah E, Ganesh A, Quigley MF, Sönnerborg A, Andersson J, Hunt PW, Somsouk M, Deeks SG, Martin JN, Moll M, Shacklett BL, Sandberg JK. PMID: 23243281; PMCID: PMC3575756.
View in:
PubMed Mentions:
216 Fields:
Translation:
HumansCells
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Lack of evidence for mtDNA as a biomarker of innate immune activation in HIV infection. PLoS One. 2012; 7(11):e50486.
Lauring AS, Lee TH, Martin JN, Hunt PW, Deeks SG, Busch M. PMID: 23209754; PMCID: PMC3510194.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
A randomized controlled trial assessing the effects of raltegravir intensification on endothelial function in treated HIV infection. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):317-25.
Hatano H, Scherzer R, Wu Y, Harvill K, Maka K, Hoh R, Sinclair E, Palmer S, Martin JN, Busch MP, Deeks SG, Hsue PY. PMID: 22918156; PMCID: PMC3480968.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):297-301.
Underwood MR, Johns BA, Sato A, Martin JN, Deeks SG, Fujiwara T. PMID: 22878423; PMCID: PMC3804312.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration. J Infect Dis. 2013 Jan 15; 207(2):213-22.
Azzoni L, Foulkes AS, Papasavvas E, Mexas AM, Lynn KM, Mounzer K, Tebas P, Jacobson JM, Frank I, Busch MP, Deeks SG, Carrington M, O'Doherty U, Kostman J, Montaner LJ. PMID: 23105144; PMCID: PMC3532820.
View in:
PubMed Mentions:
129 Fields:
Translation:
HumansCells
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Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells. J Infect Dis. 2013 Jul; 208(1):50-6.
Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG. PMID: 23089590; PMCID: PMC3666131.
View in:
PubMed Mentions:
167 Fields:
Translation:
HumansCells
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Short communication: HIV+ viremic slow progressors maintain low regulatory T cell numbers in rectal mucosa but exhibit high T cell activation. AIDS Res Hum Retroviruses. 2013 Jan; 29(1):172-7.
Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. PMID: 22998457; PMCID: PMC3537318.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase. AIDS Res Hum Retroviruses. 2013 Feb; 29(2):207-14.
Dunham RM, Gordon SN, Vaccari M, Piatak M, Huang Y, Deeks SG, Lifson J, Franchini G, McCune JM. PMID: 22924680; PMCID: PMC3552181.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Case records of the Massachusetts General Hospital. Case 30-2012. A 54-year-old woman with HIV infection, dyspnea, and chest pain. N Engl J Med. 2012 Sep 27; 367(13):1246-54.
Deeks SG, Gandhi RT, Chae CU, Lewandrowski KB. PMID: 23013077.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Prolonged and substantial discordance in prevalence of raltegravir-resistant HIV-1 in plasma versus PBMC samples revealed by 454 "deep" sequencing. PLoS One. 2012; 7(9):e46181.
Lee GQ, Swenson LC, Poon AF, Martin JN, Hatano H, Deeks SG, Harrigan PR. PMID: 23049972; PMCID: PMC3458959.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Impact of protective killer inhibitory receptor/human leukocyte antigen genotypes on natural killer cell and T-cell function in HIV-1-infected controllers. AIDS. 2012 Sep 24; 26(15):1869-78.
Tomescu C, Duh FM, Hoh R, Viviani A, Harvill K, Martin MP, Carrington M, Deeks SG, Montaner LJ. PMID: 22874514; PMCID: PMC3810173.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansCells
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The effect of a "universal antiretroviral therapy" recommendation on HIV RNA levels among HIV-infected patients entering care with a CD4 count greater than 500/μL in a public health setting. Clin Infect Dis. 2012 Dec; 55(12):1690-7.
Geng EH, Hare CB, Kahn JO, Jain V, Van Nunnery T, Christopoulos KA, Deeks SG, Gandhi M, Havlir DV. PMID: 22955429; PMCID: PMC3501330.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCellsPHPublic Health
-
HIV infection, lymphoid fibrosis, and disease. Blood. 2012 Aug 30; 120(9):1753-4.
Deeks SG. PMID: 22936732.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Prevalence and significance of HIV-1 drug resistance mutations among patients on antiretroviral therapy with detectable low-level viremia. Antimicrob Agents Chemother. 2012 Nov; 56(11):5998-6000.
Li JZ, Gallien S, Do TD, Martin JN, Deeks S, Kuritzkes DR, Hatano H. PMID: 22890763; PMCID: PMC3486544.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
-
Human endogenous retrovirus expression is inversely associated with chronic immune activation in HIV-1 infection. PLoS One. 2012; 7(8):e41021.
Ormsby CE, Sengupta D, Tandon R, Deeks SG, Martin JN, Jones RB, Ostrowski MA, Garrison KE, Vázquez-Pérez JA, Reyes-Terán G, Nixon DF. PMID: 22879884; PMCID: PMC3413683.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Lenalidomide enhancement of human T cell functions in human immunodeficiency virus (HIV)-infected and HIV-negative CD4 T lymphocytopenic patients. Clin Exp Immunol. 2012 Aug; 169(2):182-9.
Lim H, Kane L, Schwartz JB, Hesdorffer CS, Deeks SG, Greig N, Ferrucci L, Goetzl EJ. PMID: 22774993; PMCID: PMC3406378.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
HIV: Shock and kill. Nature. 2012 Jul 25; 487(7408):439-40.
Deeks SG. PMID: 22836995.
View in:
PubMed Mentions:
354 Fields:
Translation:
HumansCells
-
Towards an HIV cure: a global scientific strategy. Nat Rev Immunol. 2012 07 20; 12(8):607-14.
International AIDS Society Scientific Working Group on HIV Cure, Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A, Lederman M, Lewin SR, Maldarelli F, Margolis D, Markowitz M, Martinez-Picado J, Mullins JI, Mellors J, Moreno S, O'Doherty U, Palmer S, Penicaud MC, Peterlin M, Poli G, Routy JP, Rouzioux C, Silvestri G, Stevenson M, Telenti A, Van Lint C, Verdin E, Woolfrey A, Zaia J, Barré-Sinoussi F. PMID: 22814509; PMCID: PMC3595991.
View in:
PubMed Mentions:
294 Fields:
Translation:
HumansCells
-
Public health: Towards a cure for HIV. Nature. 2012 Jul 18; 487(7407):293-4.
Deeks SG, Barré-Sinoussi F. PMID: 22810677.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr. 2012 Jul 01; 60 Suppl 1:S1-18.
High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, Deren S, Effros RB, Gebo K, Goronzy JJ, Justice AC, Landay A, Levin J, Miotti PG, Munk RJ, Nass H, Rinaldo CR, Shlipak MG, Tracy R, Valcour V, Vance DE, Walston JD, Volberding P, OAR Working Group on HIV and Aging. PMID: 22688010; PMCID: PMC3413877.
View in:
PubMed Mentions:
294 Fields:
Translation:
Humans
-
Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection. PLoS One. 2012; 7(6):e39311.
Champiat S, Raposo RA, Maness NJ, Lehman JL, Purtell SE, Hasenkrug AM, Miller JC, Dean H, Koff WC, Hong MA, Martin JN, Deeks SG, Spotts GE, Pilcher CD, Hecht FM, Kallas EG, Garrison KE, Nixon DF. PMID: 22768072; PMCID: PMC3387156.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans. Hum Mol Genet. 2012 Oct 01; 21(19):4334-47.
McLaren PJ, Ripke S, Pelak K, Weintrob AC, Patsopoulos NA, Jia X, Erlich RL, Lennon NJ, Kadie CM, Heckerman D, Gupta N, Haas DW, Deeks SG, Pereyra F, Walker BD, de Bakker PI, International HIV Controllers Study. PMID: 22718199; PMCID: PMC3441117.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Immunosenescence and HIV. Curr Opin Immunol. 2012 Aug; 24(4):501-6.
Deeks SG, Verdin E, McCune JM. PMID: 22658763.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansAnimals
-
Immunologic basis of cardiovascular disease in HIV-infected adults. J Infect Dis. 2012 Jun; 205 Suppl 3:S375-82.
Hsue PY, Deeks SG, Hunt PW. PMID: 22577211; PMCID: PMC3349295.
View in:
PubMed Mentions:
143 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells. Sci Transl Med. 2012 May 02; 4(132):132ra53.
Scholler J, Brady TL, Binder-Scholl G, Hwang WT, Plesa G, Hege KM, Vogel AN, Kalos M, Riley JL, Deeks SG, Mitsuyasu RT, Bernstein WB, Aronson NE, Levine BL, Bushman FD, June CH. PMID: 22553251; PMCID: PMC4368443.
View in:
PubMed Mentions:
315 Fields:
Translation:
HumansCellsCTClinical Trials
-
HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation. Clin Infect Dis. 2012 Jul; 55(1):126-36.
Armah KA, McGinnis K, Baker J, Gibert C, Butt AA, Bryant KJ, Goetz M, Tracy R, Oursler KK, Rimland D, Crothers K, Rodriguez-Barradas M, Crystal S, Gordon A, Kraemer K, Brown S, Gerschenson M, Leaf DA, Deeks SG, Rinaldo C, Kuller LH, Justice A, Freiberg M. PMID: 22534147; PMCID: PMC3493182.
View in:
PubMed Mentions:
127 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
171 Fields:
Translation:
Humans
-
A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis. AIDS. 2012 Apr 24; 26(7):805-14.
Sacre K, Hunt PW, Hsue PY, Maidji E, Martin JN, Deeks SG, Autran B, McCune JM. PMID: 22313962; PMCID: PMC4155398.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
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Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation. J Am Heart Assoc. 2012 Apr; 1(2).
Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG. PMID: 23130122; PMCID: PMC3487373.
View in:
PubMed Mentions:
59 Fields:
-
Cytomegalovirus immunoglobulin G antibody is associated with subclinical carotid artery disease among HIV-infected women. J Infect Dis. 2012 Jun 15; 205(12):1788-96.
Parrinello CM, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt PW, Deeks SG, Hodis HN, Kaplan RC. PMID: 22492856; PMCID: PMC3415890.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies. J Infect Dis. 2012 Jun; 205(11):1730-8.
Tassiopoulos K, Landay A, Collier AC, Connick E, Deeks SG, Hunt P, Lewis DE, Wilson C, Bosch R. PMID: 22448010; PMCID: PMC3415854.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Blood T-cell receptor diversity decreases during the course of HIV infection, but the potential for a diverse repertoire persists. Blood. 2012 Apr 12; 119(15):3469-77.
Baum PD, Young JJ, Schmidt D, Zhang Q, Hoh R, Busch M, Martin J, Deeks S, McCune JM. PMID: 22371879; PMCID: PMC3325037.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease. PLoS Genet. 2012 Feb; 8(2):e1002514.
Chen H, Hayashi G, Lai OY, Dilthey A, Kuebler PJ, Wong TV, Martin MP, Fernandez Vina MA, McVean G, Wabl M, Leslie KS, Maurer T, Martin JN, Deeks SG, Carrington M, Bowcock AM, Nixon DF, Liao W. PMID: 22577363; PMCID: PMC3343879.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCells
-
Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV? Clin Infect Dis. 2012 Apr; 54(7):984-94.
Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, Fiellin DA, Vanasse GJ, Butt AA, Rodriguez-Barradas MC, Gibert C, Oursler KA, Deeks SG, Bryant K, VACS Project Team. PMID: 22337823; PMCID: PMC3297653.
View in:
PubMed Mentions:
138 Fields:
Translation:
HumansCells
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Hematopoietic-stem-cell-based gene therapy for HIV disease. Cell Stem Cell. 2012 Feb 03; 10(2):137-47.
Kiem HP, Jerome KR, Deeks SG, McCune JM. PMID: 22305563; PMCID: PMC3274769.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Plasma HIV-1 RNA levels during antiretroviral therapy: how low is low enough? Clin Infect Dis. 2012 Mar 01; 54(5):733-5.
Gandhi RT, Deeks SG. PMID: 22238162; PMCID: PMC3275763.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Increased CD34+/KDR+ cells are not associated with carotid artery intima-media thickness progression in chronic HIV-positive subjects. Antivir Ther. 2012; 17(3):557-63.
Papasavvas E, Hsue P, Reynolds G, Pistilli M, Hancock A, Martin JN, Deeks SG, Montaner LJ. PMID: 22300770; PMCID: PMC3362125.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Epistatic interactions between Fc (GM) and FcγR genes and the host control of human immunodeficiency virus replication. Hum Immunol. 2012 Mar; 73(3):263-6.
Deepe RN, Kistner-Griffin E, Martin JN, Deeks SG, Pandey JP. PMID: 22213007; PMCID: PMC3288776.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium. Am J Cardiol. 2012 Mar 01; 109(5):742-7.
Hsue PY, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD. PMID: 22169125; PMCID: PMC3640832.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity. Blood. 2012 Jan 19; 119(3):745-55.
Eriksson EM, Milush JM, Ho EL, Batista MD, Holditch SJ, Keh CE, Norris PJ, Keating SM, Deeks SG, Hunt PW, Martin JN, Rosenberg MG, Hecht FM, Nixon DF. PMID: 22134167; PMCID: PMC3265199.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy. AIDS. 2011 Nov 13; 25(17):2123-31.
Hunt PW, Cao HL, Muzoora C, Ssewanyana I, Bennett J, Emenyonu N, Kembabazi A, Neilands TB, Bangsberg DR, Deeks SG, Martin JN. PMID: 21881481; PMCID: PMC3480326.
View in:
PubMed Mentions:
143 Fields:
Translation:
HumansCells
-
Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans. Genes Immun. 2012 Apr; 13(3):258-67.
Seu L, Burt TD, Witte JS, Martin JN, Deeks SG, McCune JM. PMID: 22048453; PMCID: PMC3330188.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Altered distribution of mucosal NK cells during HIV infection. Mucosal Immunol. 2012 Jan; 5(1):30-40.
Sips M, Sciaranghella G, Diefenbach T, Dugast AS, Berger CT, Liu Q, Kwon D, Ghebremichael M, Estes JD, Carrington M, Martin JN, Deeks SG, Hunt PW, Alter G. PMID: 21993602; PMCID: PMC3740353.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
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The effect of AIDS Clinical Trials Group Protocol 5164 on the time from Pneumocystis jirovecii pneumonia diagnosis to antiretroviral initiation in routine clinical practice: a case study of diffusion, dissemination, and implementation. Clin Infect Dis. 2011 Nov; 53(10):1008-14.
Geng EH, Kahn JS, Chang OC, Hare CB, Christopoulos KA, Jones D, Petersen ML, Deeks SG, Havlir DV, Gandhi M. PMID: 21960715; PMCID: PMC3193829.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Immune activation in the pathogenesis of treated chronic HIV disease: a workshop summary. AIDS Res Hum Retroviruses. 2012 May; 28(5):469-77.
Plaeger SF, Collins BS, Musib R, Deeks SG, Read S, Embry A. PMID: 21854232; PMCID: PMC3332368.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
-
Old age and anti-cytomegalovirus immunity are associated with altered T-cell reconstitution in HIV-1-infected patients. AIDS. 2011 Sep 24; 25(15):1813-22.
Appay V, Fastenackels S, Katlama C, Ait-Mohand H, Schneider L, Guihot A, Keller M, Grubeck-Loebenstein B, Simon A, Lambotte O, Hunt PW, Deeks SG, Costagliola D, Autran B, Sauce D. PMID: 21412126.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansCells
-
The role of SNPs in the α-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART. Genes Immun. 2012 Jan; 13(1):83-93.
Rajasuriar R, Booth DR, Gouillou M, Spelman T, James I, Solomon A, Chua K, Stewart G, Deeks S, Bangsberg DR, Muzoora C, Cameron PU, Hunt P, Martin J, Lewin SR. PMID: 21938017.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Risk factors for tuberculosis after highly active antiretroviral therapy initiation in the United States and Canada: implications for tuberculosis screening. J Infect Dis. 2011 Sep 15; 204(6):893-901.
Sterling TR, Lau B, Zhang J, Freeman A, Bosch RJ, Brooks JT, Deeks SG, French A, Gange S, Gebo KA, John Gill M, Horberg MA, Jacobson LP, Kirk GD, Kitahata MM, Klein MB, Martin JN, Rodriguez B, Silverberg MJ, Willig JH, Eron JJ, Goedert JJ, Hogg RS, Justice AC, McKaig RG, Napravnik S, Thorne J, Moore RD, North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of the International Epi. PMID: 21849286; PMCID: PMC3156918.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Viremia copy-years predicts mortality among treatment-naive HIV-infected patients initiating antiretroviral therapy. Clin Infect Dis. 2011 Nov; 53(9):927-35.
Mugavero MJ, Napravnik S, Cole SR, Eron JJ, Lau B, Crane HM, Kitahata MM, Willig JH, Moore RD, Deeks SG, Saag MS, Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) Cohort Study. PMID: 21890751; PMCID: PMC3189165.
View in:
PubMed Mentions:
76 Fields:
Translation:
Humans
-
Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers. J Virol. 2011 Nov; 85(21):11422-34.
Shaw JM, Hunt PW, Critchfield JW, McConnell DH, Garcia JC, Pollard RB, Somsouk M, Deeks SG, Shacklett BL. PMID: 21880771; PMCID: PMC3194952.
View in:
PubMed Mentions:
67 Fields:
Translation:
Cells
-
HIV: How to escape treatment. Nature. 2011 Aug 31; 477(7362):36-7.
Deeks SG. PMID: 21886150.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Missing data on the estimation of the prevalence of accumulated human immunodeficiency virus drug resistance in patients treated with antiretroviral drugs in north america. Am J Epidemiol. 2011 Sep 15; 174(6):727-35.
Abraham AG, Lau B, Deeks S, Moore RD, Zhang J, Eron J, Harrigan R, Gill MJ, Kitahata M, Klein M, Napravnik S, Rachlis A, Rodriguez B, Rourke S, Benson C, Bosch R, Collier A, Gebo K, Goedert J, Hogg R, Horberg M, Jacobson L, Justice A, Kirk G, Martin J, McKaig R, Silverberg M, Sterling T, Thorne J, Willig J, Gange SJ, North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic D. PMID: 21813792; PMCID: PMC3202147.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Temporal changes in HCV genotype distribution in three different high risk populations in San Francisco, California. BMC Infect Dis. 2011 Aug 02; 11:208.
Dias PT, Hahn JA, Delwart E, Edlin B, Martin J, Lum P, Evans J, Kral A, Deeks S, Busch MP, Page K. PMID: 21810243; PMCID: PMC3199778.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Retention in care and connection to care among HIV-infected patients on antiretroviral therapy in Africa: estimation via a sampling-based approach. PLoS One. 2011; 6(7):e21797.
Geng EH, Glidden DV, Bwana MB, Musinguzi N, Emenyonu N, Muyindike W, Christopoulos KA, Neilands TB, Yiannoutsos CT, Deeks SG, Bangsberg DR, Martin JN. PMID: 21818265; PMCID: PMC3144217.
View in:
PubMed Mentions:
70 Fields:
Translation:
Humans
-
Drug effectiveness explained: the mathematics of antiviral agents for HIV. Sci Transl Med. 2011 Jul 13; 3(91):91ps30.
Perelson AS, Deeks SG. PMID: 21753120; PMCID: PMC3236558.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
-
Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection. Gastroenterology. 2011 Oct; 141(4):1220-30, 1230.e1-3.
Sandler NG, Koh C, Roque A, Eccleston JL, Siegel RB, Demino M, Kleiner DE, Deeks SG, Liang TJ, Heller T, Douek DC. PMID: 21726511; PMCID: PMC3186837.
View in:
PubMed Mentions:
169 Fields:
Translation:
HumansCells
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Immune activation, CD4+ T cell counts, and viremia exhibit oscillatory patterns over time in patients with highly resistant HIV infection. PLoS One. 2011; 6(6):e21190.
Kitchen CM, Yeghiazarian L, Hoh R, McCune JM, Sinclair E, Martin JN, Deeks SG. PMID: 21701594; PMCID: PMC3118814.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Cardiovascular risks associated with abacavir and tenofovir exposure in HIV-infected persons. AIDS. 2011 Jun 19; 25(10):1289-98.
Choi AI, Vittinghoff E, Deeks SG, Weekley CC, Li Y, Shlipak MG. PMID: 21516027; PMCID: PMC3910369.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Breaking free of sample size dogma to perform innovative translational research. Sci Transl Med. 2011 Jun 15; 3(87):87ps24.
Bacchetti P, Deeks SG, McCune JM. PMID: 21677197; PMCID: PMC3134305.
View in:
PubMed Mentions:
60 Fields:
Translation:
Humans
-
Human endogenous retrovirus K106 (HERV-K106) was infectious after the emergence of anatomically modern humans. PLoS One. 2011; 6(5):e20234.
Jha AR, Nixon DF, Rosenberg MG, Martin JN, Deeks SG, Hudson RR, Garrison KE, Pillai SK. PMID: 21633511; PMCID: PMC3102101.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy. J Infect Dis. 2011 May 15; 203(10):1474-83.
Hunt PW, Martin JN, Sinclair E, Epling L, Teague J, Jacobson MA, Tracy RP, Corey L, Deeks SG. PMID: 21502083; PMCID: PMC3080892.
View in:
PubMed Mentions:
183 Fields:
Translation:
HumansCells
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Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection. J Virol. 2011 Jul; 85(14):6977-85.
SenGupta D, Tandon R, Vieira RG, Ndhlovu LC, Lown-Hecht R, Ormsby CE, Loh L, Jones RB, Garrison KE, Martin JN, York VA, Spotts G, Reyes-Terán G, Ostrowski MA, Hecht FM, Deeks SG, Nixon DF. PMID: 21525339; PMCID: PMC3126607.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
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Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter. J Virol Methods. 2011 Aug; 175(2):261-5.
Yukl SA, Li P, Fujimoto K, Lampiris H, Lu CM, Hare CB, Deeks SG, Liegler T, Pandori M, Havlir DV, Wong JK. PMID: 21536073; PMCID: PMC3827908.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Differential microRNA regulation of HLA-C expression and its association with HIV control. Nature. 2011 Apr 28; 472(7344):495-8.
Kulkarni S, Savan R, Qi Y, Gao X, Yuki Y, Bass SE, Martin MP, Hunt P, Deeks SG, Telenti A, Pereyra F, Goldstein D, Wolinsky S, Walker B, Young HA, Carrington M. PMID: 21499264; PMCID: PMC3084326.
View in:
PubMed Mentions:
187 Fields:
Translation:
HumansCells
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Differential persistence of transmitted HIV-1 drug resistance mutation classes. J Infect Dis. 2011 Apr 15; 203(8):1174-81.
Jain V, Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Janini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM. PMID: 21451005; PMCID: PMC3107558.
View in:
PubMed Mentions:
74 Fields:
Translation:
HumansCells
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A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response. J Infect Dis. 2011 Apr 01; 203(7):960-8.
Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG. PMID: 21402547; PMCID: PMC3068029.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansCells
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HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis. Blood. 2011 May 12; 117(19):5142-51.
Sauce D, Larsen M, Fastenackels S, Pauchard M, Ait-Mohand H, Schneider L, Guihot A, Boufassa F, Zaunders J, Iguertsira M, Bailey M, Gorochov G, Duvivier C, Carcelain G, Kelleher AD, Simon A, Meyer L, Costagliola D, Deeks SG, Lambotte O, Autran B, Hunt PW, Katlama C, Appay V. PMID: 21436070; PMCID: PMC3109539.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansCells
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T cell activation predicts carotid artery stiffness among HIV-infected women. Atherosclerosis. 2011 Jul; 217(1):207-13.
Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Parrinello CM, Hunt P, Deeks SG, Hodis HN. PMID: 21492857; PMCID: PMC3139014.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCells
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N-terminal-proB-type natriuretic peptide predicts cardiovascular disease events in HIV-infected patients. AIDS. 2011 Mar 13; 25(5):651-7.
Duprez DA, Neuhaus J, Tracy R, Kuller LH, Deeks SG, Orkin C, Stoehr A, Woolley IJ, Neaton JD, INSIGHT SMART Group. PMID: 21245726; PMCID: PMC3113476.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression. Blood. 2011 Apr 07; 117(14):3799-808.
Hersperger AR, Martin JN, Shin LY, Sheth PM, Kovacs CM, Cosma GL, Makedonas G, Pereyra F, Walker BD, Kaul R, Deeks SG, Betts MR. PMID: 21289310; PMCID: PMC3083297.
View in:
PubMed Mentions:
107 Fields:
Translation:
HumansCells
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A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. PLoS One. 2011 Jan 31; 6(1):e15924.
Hunt PW, Landay AL, Sinclair E, Martinson JA, Hatano H, Emu B, Norris PJ, Busch MP, Martin JN, Brooks C, McCune JM, Deeks SG. PMID: 21305005; PMCID: PMC3031543.
View in:
PubMed Mentions:
76 Fields:
Translation:
Cells
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Association of vitamin D insufficiency with carotid intima-media thickness in HIV-infected persons. Clin Infect Dis. 2011 Apr 01; 52(7):941-4.
Choi AI, Lo JC, Mulligan K, Schnell A, Kalapus SC, Li Y, Hunt PW, Martin JN, Deeks SG, Hsue PY. PMID: 21273298; PMCID: PMC3106229.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis. 2011 Mar 15; 203(6):780-90.
Sandler NG, Wand H, Roque A, Law M, Nason MC, Nixon DE, Pedersen C, Ruxrungtham K, Lewin SR, Emery S, Neaton JD, Brenchley JM, Deeks SG, Sereti I, Douek DC, INSIGHT SMART Study Group. PMID: 21252259; PMCID: PMC3071127.
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PubMed Mentions:
654 Fields:
Translation:
HumansCells
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Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression. J Virol. 2011 Apr; 85(7):3367-74.
Corrah TW, Goonetilleke N, Kopycinski J, Deeks SG, Cohen MS, Borrow P, McMichael A, Brackenridge S. PMID: 21248048; PMCID: PMC3067890.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
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HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllers. Clin Infect Dis. 2011 Mar 01; 52(5):681-7.
Hunt PW, Hatano H, Sinclair E, Lee TH, Busch MP, Martin JN, McCune JM, Deeks SG. PMID: 21245154; PMCID: PMC3060894.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women. J Infect Dis. 2011 Feb 15; 203(4):452-63.
Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt P, Karim R, Kern DM, Hodis HN, Deeks SG. PMID: 21220772; PMCID: PMC3071219.
View in:
PubMed Mentions:
162 Fields:
Translation:
HumansCells
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HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells. Blood. 2011 Feb 17; 117(7):2189-99.
Favre D, Stoddart CA, Emu B, Hoh R, Martin JN, Hecht FM, Deeks SG, McCune JM. PMID: 21200021; PMCID: PMC3062328.
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HIV infection, inflammation, immunosenescence, and aging. Annu Rev Med. 2011; 62:141-55.
Deeks SG. PMID: 21090961; PMCID: PMC3759035.
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PubMed Mentions:
643 Fields:
Translation:
HumansCells
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CD4 count at presentation for HIV care in the United States and Canada: are those over 50 years more likely to have a delayed presentation? AIDS Res Ther. 2010 Dec 15; 7:45.
Althoff KN, Gebo KA, Gange SJ, Klein MB, Brooks JT, Hogg RS, Bosch RJ, Horberg MA, Saag MS, Kitahata MM, Eron JJ, Napravnik S, Rourke SB, Gill MJ, Rodriguez B, Sterling TR, Deeks SG, Martin JN, Jacobson LP, Kirk GD, Collier AC, Benson CA, Silverberg MJ, Goedert JJ, McKaig RG, Thorne J, Rachlis A, Moore RD, Justice AC, North American AIDS Cohort Collaboration on Research and Design. PMID: 21159161; PMCID: PMC3022663.
View in:
PubMed Mentions:
38 Fields:
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Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009. PLoS One. 2010 Dec 10; 5(12):e15510.
Jain V, Liegler T, Vittinghoff E, Hartogensis W, Bacchetti P, Poole L, Loeb L, Pilcher CD, Grant RM, Deeks SG, Hecht FM. PMID: 21170322; PMCID: PMC3000814.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Risk of viral failure declines with duration of suppression on highly active antiretroviral therapy irrespective of adherence level. J Acquir Immune Defic Syndr. 2010 Dec; 55(4):460-5.
Lima VD, Bangsberg DR, Harrigan PR, Deeks SG, Yip B, Hogg RS, Montaner JS. PMID: 20838225; PMCID: PMC2974791.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansCells
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A single tablet regimen is associated with higher adherence and viral suppression than multiple tablet regimens in HIV+ homeless and marginally housed people. AIDS. 2010 Nov 27; 24(18):2835-40.
Bangsberg DR, Ragland K, Monk A, Deeks SG. PMID: 21045636; PMCID: PMC3540404.
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PubMed Mentions:
71 Fields:
Translation:
HumansCells
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Treatment-mediated alterations in HIV fitness preserve CD4+ T cell counts but have minimal effects on viral load. PLoS Comput Biol. 2010 Nov 24; 6(11):e1001012.
Vaidya NK, Rong L, Marconi VC, Kuritzkes DR, Deeks SG, Perelson AS. PMID: 21124866; PMCID: PMC2991251.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7.
International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, et al. PMID: 21051598; PMCID: PMC3235490.
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PubMed Mentions:
689 Fields:
Translation:
HumansCells
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Biomarkers in HIV disease. Curr Opin HIV AIDS. 2010 Nov; 5(6):459-62.
Lundgren JD, Baxter J, Deeks SG, Lane HC. PMID: 20978387.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Evidence of persistent low-level viremia in long-term HAART-suppressed, HIV-infected individuals. AIDS. 2010 Oct 23; 24(16):2535-9.
Hatano H, Delwart EL, Norris PJ, Lee TH, Neilands TB, Kelley CF, Hunt PW, Hoh R, Linnen JM, Martin JN, Busch MP, Deeks SG. PMID: 20651585; PMCID: PMC2954261.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Virologic and immunologic response to HAART, by age and regimen class. AIDS. 2010 Oct 23; 24(16):2469-79.
Althoff KN, Justice AC, Gange SJ, Deeks SG, Saag MS, Silverberg MJ, Gill MJ, Lau B, Napravnik S, Tedaldi E, Klein MB, Gebo KA, North American AIDS Cohorts Collaboration on Research, Design (NA-ACCORD). PMID: 20829678; PMCID: PMC3136814.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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HIV controllers with HLA-DRB1*13 and HLA-DQB1*06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses. J Virol. 2010 Nov; 84(21):11020-9.
Ferre AL, Hunt PW, McConnell DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 20719952; PMCID: PMC2953185.
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PubMed Mentions:
68 Fields:
Translation:
HumansCells
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Intracellular Casp8p41 content is inversely associated with CD4 T cell count. J Infect Dis. 2010 Aug 15; 202(3):386-91.
Cummins NW, Jiang W, McGinty J, Bren GD, Bosch RJ, Landay A, Deeks SG, Martin JN, Douek D, Lederman MM, Brenchley J, Badley AD. PMID: 20565257; PMCID: PMC2906377.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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A maraviroc-resistant HIV-1 with narrow cross-resistance to other CCR5 antagonists depends on both N-terminal and extracellular loop domains of drug-bound CCR5. J Virol. 2010 Oct; 84(20):10863-76.
Tilton JC, Wilen CB, Didigu CA, Sinha R, Harrison JE, Agrawal-Gamse C, Henning EA, Bushman FD, Martin JN, Deeks SG, Doms RW. PMID: 20702642; PMCID: PMC2950574.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Evolution of integrase resistance during failure of integrase inhibitor-based antiretroviral therapy. J Acquir Immune Defic Syndr. 2010 Aug; 54(4):389-93.
Hatano H, Lampiris H, Fransen S, Gupta S, Huang W, Hoh R, Martin JN, Lalezari J, Bangsberg D, Petropoulos C, Deeks SG. PMID: 20300008; PMCID: PMC2890029.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Can HIV be cured with stem cell therapy? Nat Biotechnol. 2010 Aug; 28(8):807-10.
Deeks SG, McCune JM. PMID: 20697404.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Initiation of antiretroviral therapy at higher nadir CD4+ T-cell counts is associated with reduced arterial stiffness in HIV-infected individuals. AIDS. 2010 Jul 31; 24(12):1897-905.
Ho JE, Deeks SG, Hecht FM, Xie Y, Schnell A, Martin JN, Ganz P, Hsue PY. PMID: 20543654; PMCID: PMC2903431.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Immunodominant HIV-specific CD8+ T-cell responses are common to blood and gastrointestinal mucosa, and Gag-specific responses dominate in rectal mucosa of HIV controllers. J Virol. 2010 Oct; 84(19):10354-65.
Ferre AL, Lemongello D, Hunt PW, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 20668079; PMCID: PMC2937770.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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How do HIV elite controllers do what they do? Clin Infect Dis. 2010 Jul 15; 51(2):239-41.
Saag M, Deeks SG. PMID: 20550453.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Antiretroviral therapy and management of HIV infection. Lancet. 2010 Jul 03; 376(9734):49-62.
Volberding PA, Deeks SG. PMID: 20609987.
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PubMed Mentions:
177 Fields:
Translation:
Humans
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Tracking a sample of patients lost to follow-up has a major impact on understanding determinants of survival in HIV-infected patients on antiretroviral therapy in Africa. Trop Med Int Health. 2010 Jun; 15 Suppl 1:63-9.
Geng EH, Glidden DV, Emenyonu N, Musinguzi N, Bwana MB, Neilands TB, Muyindike W, Yiannoutsos CT, Deeks SG, Bangsberg DR, Martin JN. PMID: 20586962; PMCID: PMC3038920.
View in:
PubMed Mentions:
58 Fields:
Translation:
Humans
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Late presentation for human immunodeficiency virus care in the United States and Canada. Clin Infect Dis. 2010 Jun 01; 50(11):1512-20.
Althoff KN, Gange SJ, Klein MB, Brooks JT, Hogg RS, Bosch RJ, Horberg MA, Saag MS, Kitahata MM, Justice AC, Gebo KA, Eron JJ, Rourke SB, Gill MJ, Rodriguez B, Sterling TR, Calzavara LM, Deeks SG, Martin JN, Rachlis AR, Napravnik S, Jacobson LP, Kirk GD, Collier AC, Benson CA, Silverberg MJ, Kushel M, Goedert JJ, McKaig RG, Van Rompaey SE, Zhang J, Moore RD. PMID: 20415573; PMCID: PMC2862849.
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PubMed Mentions:
114 Fields:
Translation:
Humans
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Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci Transl Med. 2010 May 19; 2(32):32ra36.
Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM. PMID: 20484731; PMCID: PMC3034445.
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PubMed Mentions:
299 Fields:
Translation:
HumansCells
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HIV+ elite controllers have low HIV-specific T-cell activation yet maintain strong, polyfunctional T-cell responses. AIDS. 2010 May 15; 24(8):1095-105.
Owen RE, Heitman JW, Hirschkorn DF, Lanteri MC, Biswas HH, Martin JN, Krone MR, Deeks SG, Norris PJ, NIAID Center for HIV/AIDS Vaccine Immunology. PMID: 20400885; PMCID: PMC2972651.
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PubMed Mentions:
82 Fields:
Translation:
HumansCells
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Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection. Nature. 2010 May 20; 465(7296):350-4.
Kosmrlj A, Read EL, Qi Y, Allen TM, Altfeld M, Deeks SG, Pereyra F, Carrington M, Walker BD, Chakraborty AK. PMID: 20445539; PMCID: PMC3098720.
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PubMed Mentions:
159 Fields:
Translation:
HumansCells
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When to start antiretroviral therapy. Curr HIV/AIDS Rep. 2010 May; 7(2):60-8.
Jain V, Deeks SG. PMID: 20425559; PMCID: PMC2856854.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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HIV RNA level in early infection is predicted by viral load in the transmission source. AIDS. 2010 Apr 24; 24(7):941-5.
Hecht FM, Hartogensis W, Bragg L, Bacchetti P, Atchison R, Grant R, Barbour J, Deeks SG. PMID: 20168202; PMCID: PMC2887742.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCellsPHPublic Health
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Cerebrospinal fluid in HIV-1 systemic viral controllers: absence of HIV-1 RNA and intrathecal inflammation. AIDS. 2010 Apr 24; 24(7):1001-5.
Probasco JC, Deeks SG, Lee E, Hoh R, Hunt PW, Liegler T, Price RW, Spudich SS. PMID: 20299968.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Understanding reasons for and outcomes of patients lost to follow-up in antiretroviral therapy programs in Africa through a sampling-based approach. J Acquir Immune Defic Syndr. 2010 Mar; 53(3):405-11.
Geng EH, Bangsberg DR, Musinguzi N, Emenyonu N, Bwana MB, Yiannoutsos CT, Glidden DV, Deeks SG, Martin JN. PMID: 19745753; PMCID: PMC3606953.
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PubMed Mentions:
193 Fields:
Translation:
Humans
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Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers. Blood. 2010 Apr 15; 115(15):e20-32.
Loke P, Favre D, Hunt PW, Leung JM, Kanwar B, Martin JN, Deeks SG, McCune JM. PMID: 20160163; PMCID: PMC2858476.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease. PLoS One. 2010 Jan 29; 5(1):e8886.
Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG. PMID: 20126452; PMCID: PMC2813282.
View in:
PubMed Mentions:
112 Fields:
Translation:
HumansCells
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Association between kidney function and albuminuria with cardiovascular events in HIV-infected persons. Circulation. 2010 Feb 09; 121(5):651-8.
Choi AI, Li Y, Deeks SG, Grunfeld C, Volberding PA, Shlipak MG. PMID: 20100969; PMCID: PMC2829672.
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PubMed Mentions:
81 Fields:
Translation:
Humans
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Spending more to save more: interventions to promote adherence. Ann Intern Med. 2010 Jan 05; 152(1):54-6; W-13.
Bangsberg DR, Deeks SG. PMID: 20048272; PMCID: PMC3606957.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C. Nat Genet. 2009 Dec; 41(12):1290-4.
Thomas R, Apps R, Qi Y, Gao X, Male V, O'hUigin C, O'Connor G, Ge D, Fellay J, Martin JN, Margolick J, Goedert JJ, Buchbinder S, Kirk GD, Martin MP, Telenti A, Deeks SG, Walker BD, Goldstein D, McVicar DW, Moffett A, Carrington M. PMID: 19935663; PMCID: PMC2887091.
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PubMed Mentions:
163 Fields:
Translation:
Humans
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Impact of HIV infection on diastolic function and left ventricular mass. Circ Heart Fail. 2010 Jan; 3(1):132-9.
Hsue PY, Hunt PW, Ho JE, Farah HH, Schnell A, Hoh R, Martin JN, Deeks SG, Bolger AF. PMID: 19933410; PMCID: PMC2837081.
View in:
PubMed Mentions:
99 Fields:
Translation:
Humans
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Trends in multidrug treatment failure and subsequent mortality among antiretroviral therapy-experienced patients with HIV infection in North America. Clin Infect Dis. 2009 Nov 15; 49(10):1582-90.
Deeks SG, Gange SJ, Kitahata MM, Saag MS, Justice AC, Hogg RS, Eron JJ, Brooks JT, Rourke SB, Gill MJ, Bosch RJ, Benson CA, Collier AC, Martin JN, Klein MB, Jacobson LP, Rodriguez B, Sterling TR, Kirk GD, Napravnik S, Rachlis AR, Calzavara LM, Horberg MA, Silverberg MJ, Gebo KA, Kushel MB, Goedert JJ, McKaig RG, Moore RD. PMID: 19845473; PMCID: PMC2871149.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
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HIV-infected persons continue to lose kidney function despite successful antiretroviral therapy. AIDS. 2009 Oct 23; 23(16):2143-9.
Choi AI, Shlipak MG, Hunt PW, Martin JN, Deeks SG. PMID: 19684507; PMCID: PMC2839451.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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The risk of virologic failure decreases with duration of HIV suppression, at greater than 50% adherence to antiretroviral therapy. PLoS One. 2009 Sep 29; 4(9):e7196.
Rosenblum M, Deeks SG, van der Laan M, Bangsberg DR. PMID: 19787058; PMCID: PMC2747009.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS. 2009 Sep 24; 23(15):2021-7.
Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG. PMID: 19542863; PMCID: PMC2785446.
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PubMed Mentions:
60 Fields:
Translation:
HumansCells
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Lower cytokine secretion ex vivo by natural killer T cells in HIV-infected individuals is associated with higher CD161 expression. AIDS. 2009 Sep 24; 23(15):1965-70.
Snyder-Cappione JE, Loo CP, Carvalho KI, Kuylenstierna C, Deeks SG, Hecht FM, Rosenberg MG, Sandberg JK, Kallas EG, Nixon DF. PMID: 19590406.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Reduced thymus activity and infection prematurely age the immune system. J Clin Invest. 2009 Oct; 119(10):2884-7.
Gress RE, Deeks SG. PMID: 19770512; PMCID: PMC2752092.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy. Top HIV Med. 2009 Sep-Oct; 17(4):118-23.
Deeks SG. PMID: 19890183.
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PubMed Mentions:
136 Fields:
Translation:
Humans
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Cross-sectional dating of novel haplotypes of HERV-K 113 and HERV-K 115 indicate these proviruses originated in Africa before Homo sapiens. Mol Biol Evol. 2009 Nov; 26(11):2617-26.
Jha AR, Pillai SK, York VA, Sharp ER, Storm EC, Wachter DJ, Martin JN, Deeks SG, Rosenberg MG, Nixon DF, Garrison KE. PMID: 19666991; PMCID: PMC2760466.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individuals. AIDS Res Hum Retroviruses. 2009 Aug; 25(8):795-802.
Huang W, Toma J, Stawiski E, Fransen S, Wrin T, Parkin N, Whitcomb JM, Coakley E, Hecht FM, Deeks SG, Gandhi RT, Eshleman SH, Petropoulos CJ. PMID: 19678765; PMCID: PMC2827835.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Transcriptional errors in human immunodeficiency virus type 1 generate targets for T-cell responses. Clin Vaccine Immunol. 2009 Sep; 16(9):1369-71.
Garrison KE, Champiat S, York VA, Agrawal AT, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF. PMID: 19571107; PMCID: PMC2745002.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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A step ahead on the HIV collaboratory. Science. 2009 Jun 05; 324(5932):1264-5.
Murphy RL, Autran B, Katlama C, Brucker G, Debre P, Calvez V, Clotet B, Clumeck N, Costagliola D, Deeks SG, Dorrell L, Gatell J, Haase A, Klein M, Lazzarin A, McMichael AJ, Papagno L, Schacker TW, Wain-Hobson S, Walker BD, Youle M. PMID: 19498149.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis. AIDS. 2009 Jun 01; 23(9):1059-67.
Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG. PMID: 19390417; PMCID: PMC2691772.
View in:
PubMed Mentions:
193 Fields:
Translation:
HumansCells
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Human herpesvirus replication and abnormal CD8+ T cell activation and low CD4+ T cell counts in antiretroviral-suppressed HIV-infected patients. PLoS One. 2009; 4(4):e5277.
Jacobson MA, Ditmer DP, Sinclair E, Martin JN, Deeks SG, Hunt P, Mocarski ES, Shiboski C. PMID: 19381272; PMCID: PMC2667217.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. J Infect Dis. 2009 Apr 15; 199(8):1177-85.
Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM. PMID: 19265479; PMCID: PMC2728622.
View in:
PubMed Mentions:
339 Fields:
Translation:
HumansCellsCTClinical Trials
-
Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med. 2009 Apr 30; 360(18):1815-26.
Kitahata MM, Gange SJ, Abraham AG, Merriman B, Saag MS, Justice AC, Hogg RS, Deeks SG, Eron JJ, Brooks JT, Rourke SB, Gill MJ, Bosch RJ, Martin JN, Klein MB, Jacobson LP, Rodriguez B, Sterling TR, Kirk GD, Napravnik S, Rachlis AR, Calzavara LM, Horberg MA, Silverberg MJ, Gebo KA, Goedert JJ, Benson CA, Collier AC, Van Rompaey SE, Crane HM, McKaig RG, Lau B, Freeman AM, Moore RD, NA-ACCORD Investigators. PMID: 19339714; PMCID: PMC2854555.
View in:
PubMed Mentions:
496 Fields:
Translation:
HumansCells
-
Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment. Clin Infect Dis. 2009 Mar 15; 48(6):787-94.
Kelley CF, Kitchen CM, Hunt PW, Rodriguez B, Hecht FM, Kitahata M, Crane HM, Willig J, Mugavero M, Saag M, Martin JN, Deeks SG. PMID: 19193107; PMCID: PMC2720023.
View in:
PubMed Mentions:
185 Fields:
Translation:
Humans
-
Delaying a treatment switch in antiretroviral-treated HIV type 1-infected patients with detectable drug-resistant viremia does not have a profound effect on immune parameters: AIDS Clinical Trials Group Study A5115. AIDS Res Hum Retroviruses. 2009 Feb; 25(2):135-9.
Tenorio AR, Jiang H, Zheng Y, Bastow B, Kuritzkes DR, Bartlett JA, Deeks SG, Landay AL, Riddler SA. PMID: 19239354; PMCID: PMC2755543.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
CD4+ T cell recovery with antiretroviral therapy: more than the sum of the parts. Clin Infect Dis. 2009 Feb 01; 48(3):362-4.
Geng EH, Deeks SG. PMID: 19123869.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity. BMJ. 2009 Jan 26; 338:a3172.
Deeks SG, Phillips AN. PMID: 19171560.
View in:
PubMed Mentions:
311 Fields:
Translation:
Humans
-
Two-way Bayesian hierarchical phylogenetic models: An application to the co-evolution of gp120 and gp41 during and after enfuvirtide treatment. Comput Stat Data Anal. 2009 Jan 15; 53(3):766-775.
Kitchen CM, Kroll J, Kuritzkes DR, Bloomquist E, Deeks SG, Suchard MA. PMID: 20442796; PMCID: PMC2862497.
View in:
PubMed Mentions:
3
-
Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells. J Biol Chem. 2009 Mar 13; 284(11):6782-9.
Contreras X, Schweneker M, Chen CS, McCune JM, Deeks SG, Martin J, Peterlin BM. PMID: 19136668; PMCID: PMC2652322.
View in:
PubMed Mentions:
184 Fields:
Translation:
HumansCells
-
Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. Blood. 2009 Apr 23; 113(17):3978-89.
Ferre AL, Hunt PW, Critchfield JW, Young DH, Morris MM, Garcia JC, Pollard RB, Yee HF, Martin JN, Deeks SG, Shacklett BL. PMID: 19109229; PMCID: PMC2673124.
View in:
PubMed Mentions:
124 Fields:
Translation:
HumansCells
-
In vivo fitness cost of the M184V mutation in multidrug-resistant human immunodeficiency virus type 1 in the absence of lamivudine. J Virol. 2009 Feb; 83(4):2038-43.
Paredes R, Sagar M, Marconi VC, Hoh R, Martin JN, Parkin NT, Petropoulos CJ, Deeks SG, Kuritzkes DR. PMID: 19019971; PMCID: PMC2643770.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
-
Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy. J Virol. 2009 Jan; 83(1):329-35.
Hatano H, Delwart EL, Norris PJ, Lee TH, Dunn-Williams J, Hunt PW, Hoh R, Stramer SL, Linnen JM, McCune JM, Martin JN, Busch MP, Deeks SG. PMID: 18945778; PMCID: PMC2612329.
View in:
PubMed Mentions:
118 Fields:
Translation:
HumansCells
-
Long-term consequences of the delay between virologic failure of highly active antiretroviral therapy and regimen modification. AIDS. 2008 Oct 18; 22(16):2097-106.
Petersen ML, van der Laan MJ, Napravnik S, Eron JJ, Moore RD, Deeks SG. PMID: 18832873; PMCID: PMC2597677.
View in:
PubMed Mentions:
69 Fields:
Translation:
Humans
-
Viral dynamics and in vivo fitness of HIV-1 in the presence and absence of enfuvirtide. J Acquir Immune Defic Syndr. 2008 Aug 15; 48(5):572-6.
Marconi V, Bonhoeffer S, Paredes R, Lu J, Hoh R, Martin JN, Deeks SG, Kuritzkes DR. PMID: 18645515; PMCID: PMC2709806.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Failure of atorvastatin to modulate CSF HIV-1 infection: results of a pilot study. Neurology. 2008 Aug 12; 71(7):521-4.
Probasco JC, Spudich SS, Critchfield J, Lee E, Lollo N, Deeks SG, Price RW. PMID: 18695163; PMCID: PMC2676982.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCellsCTClinical Trials
-
Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels. PLoS One. 2008 Jul 30; 3(7):e2783.
Parienti JJ, Das-Douglas M, Massari V, Guzman D, Deeks SG, Verdon R, Bangsberg DR. PMID: 18665246; PMCID: PMC2467488.
View in:
PubMed Mentions:
111 Fields:
Translation:
HumansCells
-
Transmitted minority drug-resistant HIV variants: a new epidemic? PLoS Med. 2008 Jul 29; 5(7):e164.
Deeks SG. PMID: 18666826; PMCID: PMC2488200.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
HIV-induced changes in T cell signaling pathways. J Immunol. 2008 May 15; 180(10):6490-500.
Schweneker M, Favre D, Martin JN, Deeks SG, McCune JM. PMID: 18453567; PMCID: PMC2648824.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Role of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension. AIDS. 2008 Apr 23; 22(7):825-33.
Hsue PY, Deeks SG, Farah HH, Palav S, Ahmed SY, Schnell A, Ellman AB, Huang L, Dollard SC, Martin JN. PMID: 18427200; PMCID: PMC2711076.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansCells
-
Antiretroviral treatment effect on immune activation reduces cerebrospinal fluid HIV-1 infection. J Acquir Immune Defic Syndr. 2008 Apr 15; 47(5):544-52.
Sinclair E, Ronquillo R, Lollo N, Deeks SG, Hunt P, Yiannoutsos CT, Spudich S, Price RW. PMID: 18362693; PMCID: PMC3480328.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
-
CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. Nat Med. 2008 Apr; 14(4):413-20.
Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, Little S, Richman D, Hecht FM, Dolan MJ. PMID: 18376407; PMCID: PMC2630879.
View in:
PubMed Mentions:
64 Fields:
Translation:
Humans
-
HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J Virol. 2008 Jun; 82(11):5398-407.
Emu B, Sinclair E, Hatano H, Ferre A, Shacklett B, Martin JN, McCune JM, Deeks SG. PMID: 18353945; PMCID: PMC2395228.
View in:
PubMed Mentions:
141 Fields:
Translation:
HumansCells
-
Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J Infect Dis. 2008 Jan 01; 197(1):126-33.
Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, Page-Shafer K, Hsue P, Emu B, Krone M, Lampiris H, Douek D, Martin JN, Deeks SG. PMID: 18171295; PMCID: PMC3466592.
View in:
PubMed Mentions:
371 Fields:
Translation:
HumansCells
-
Enfuvirtide cerebrospinal fluid (CSF) pharmacokinetics and potential use in defining CSF HIV-1 origin. Antivir Ther. 2008; 13(3):369-74.
Price RW, Parham R, Kroll JL, Wring SA, Baker B, Sailstad J, Hoh R, Liegler T, Spudich S, Kuritzkes DR, Deeks SG. PMID: 18572749; PMCID: PMC2699482.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Dysfunctional natural killer cells, in vivo, are governed by HIV viremia regardless of whether the infected individual is on antiretroviral therapy. AIDS. 2007 Nov 12; 21(17):2363-5.
Barker E, Martinson J, Brooks C, Landay A, Deeks S. PMID: 18090295.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Individualized treatment rules: generating candidate clinical trials. Stat Med. 2007 Nov 10; 26(25):4578-601.
Petersen ML, Deeks SG, van der Laan MJ. PMID: 17450501; PMCID: PMC2442037.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms. Nat Immunol. 2007 Dec; 8(12):1324-36.
Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, Anaya JM, Miura T, Hecht FM, Mamtani M, Pereyra F, Marconi V, Mangano A, Sen L, Bologna R, Clark RA, Anderson SA, Delmar J, O'Connell RJ, Lloyd A, Martin J, Ahuja SS, Agan BK, Walker BD, Deeks SG, Ahuja SK. PMID: 17952079.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansCells
-
History-adjusted marginal structural models for estimating time-varying effect modification. Am J Epidemiol. 2007 Nov 01; 166(9):985-93.
Petersen ML, Deeks SG, Martin JN, van der Laan MJ. PMID: 17875580; PMCID: PMC2561999.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
-
Protease inhibitors as immunomodulatory drugs for HIV infection. Clin Pharmacol Ther. 2007 Sep; 82(3):248-50.
Deeks SG. PMID: 17700590.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity. 2007 Sep; 27(3):406-16.
Deeks SG, Walker BD. PMID: 17892849.
View in:
PubMed Mentions:
381 Fields:
Translation:
HumansAnimalsCells
-
Loss of T cell responses following long-term cryopreservation. J Immunol Methods. 2007 Sep 30; 326(1-2):93-115.
Owen RE, Sinclair E, Emu B, Heitman JW, Hirschkorn DF, Epling CL, Tan QX, Custer B, Harris JM, Jacobson MA, McCune JM, Martin JN, Hecht FM, Deeks SG, Norris PJ. PMID: 17707394; PMCID: PMC2065759.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
-
Antiretroviral drug therapy alters the profile of human immunodeficiency virus type 1-specific T-cell responses and shifts the immunodominant cytotoxic T-lymphocyte response from Gag to Pol. J Virol. 2007 Oct; 81(20):11543-8.
Karlsson AC, Chapman JM, Heiken BD, Hoh R, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF. PMID: 17670829; PMCID: PMC2045537.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
A new approach for 'deep salvage' trials in advanced HIV infection. AIDS. 2007 Jul 31; 21(12):1503-6.
Lederman MM, Miller V, Weller I, Deeks SG. PMID: 17630543.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Drug resistant HIV. BMJ. 2007 Jun 02; 334(7604):1124-5.
Hatano H, Deeks SG. PMID: 17540912; PMCID: PMC1885311.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Genet. 2007 Jun; 39(6):733-40.
Martin MP, Qi Y, Gao X, Yamada E, Martin JN, Pereyra F, Colombo S, Brown EE, Shupert WL, Phair J, Goedert JJ, Buchbinder S, Kirk GD, Telenti A, Connors M, O'Brien SJ, Walker BD, Parham P, Deeks SG, McVicar DW, Carrington M. PMID: 17496894; PMCID: PMC4135476.
View in:
PubMed Mentions:
417 Fields:
Translation:
HumansCells
-
Adherence-resistance relationships to combination HIV antiretroviral therapy. Curr HIV/AIDS Rep. 2007 May; 4(2):65-72.
Bangsberg DR, Kroetz DL, Deeks SG. PMID: 17547827.
View in:
PubMed Mentions:
99 Fields:
Translation:
Humans
-
Clinical resistance to enfuvirtide does not affect susceptibility of human immunodeficiency virus type 1 to other classes of entry inhibitors. J Virol. 2007 Apr; 81(7):3240-50.
Ray N, Harrison JE, Blackburn LA, Martin JN, Deeks SG, Doms RW. PMID: 17251281; PMCID: PMC1866075.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
-
Comparison of an interferon-gamma release assay with tuberculin skin testing in HIV-infected individuals. Am J Respir Crit Care Med. 2007 Apr 01; 175(7):737-42.
Luetkemeyer AF, Charlebois ED, Flores LL, Bangsberg DR, Deeks SG, Martin JN, Havlir DV. PMID: 17218620; PMCID: PMC1899289.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCTClinical Trials
-
Cohort profile: the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). Int J Epidemiol. 2007 Apr; 36(2):294-301.
Gange SJ, Kitahata MM, Saag MS, Bangsberg DR, Bosch RJ, Brooks JT, Calzavara L, Deeks SG, Eron JJ, Gebo KA, Gill MJ, Haas DW, Hogg RS, Horberg MA, Jacobson LP, Justice AC, Kirk GD, Klein MB, Martin JN, McKaig RG, Rodriguez B, Rourke SB, Sterling TR, Freeman AM, Moore RD. PMID: 17213214; PMCID: PMC2820873.
View in:
PubMed Mentions:
145 Fields:
Translation:
Humans
-
A randomized study of antiviral medication switch at lower- versus higher-switch thresholds: AIDS Clinical Trials Group Study A5115. Antivir Ther. 2007; 12(4):531-41.
Riddler SA, Jiang H, Tenorio A, Huang H, Kuritzkes DR, Acosta EP, Landay A, Bastow B, Haas DW, Tashima KT, Jain MK, Deeks SG, Bartlett JA. PMID: 17668562.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Partial treatment interruptions. Curr Opin HIV AIDS. 2007 Jan; 2(1):46-55.
Deeks SG, Martin JN. PMID: 19372865.
View in:
PubMed Mentions: Fields:
-
Interruption of enfuvirtide in HIV-1 infected adults with incomplete viral suppression on an enfuvirtide-based regimen. J Infect Dis. 2007 Feb 01; 195(3):387-91.
Deeks SG, Lu J, Hoh R, Neilands TB, Beatty G, Huang W, Liegler T, Hunt P, Martin JN, Kuritzkes DR. PMID: 17205477.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCellsCTClinical Trials
-
Continued evolution in gp41 after interruption of enfuvirtide in subjects with advanced HIV type 1 disease. AIDS Res Hum Retroviruses. 2006 Dec; 22(12):1260-6.
Kitchen CM, Lu J, Suchard MA, Hoh R, Martin JN, Kuritzkes DR, Deeks SG. PMID: 17209769.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses. AIDS. 2006 Nov 28; 20(18):2275-83.
Hsue PY, Hunt PW, Sinclair E, Bredt B, Franklin A, Killian M, Hoh R, Martin JN, McCune JM, Waters DD, Deeks SG. PMID: 17117013.
View in:
PubMed Mentions:
141 Fields:
Translation:
HumansCells
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med. 2006 Dec; 12(12):1365-71.
Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. PMID: 17115046.
View in:
PubMed Mentions:
1825 Fields:
Translation:
HumansAnimalsCells
-
Treatment benefit on cerebrospinal fluid HIV-1 levels in the setting of systemic virological suppression and failure. J Infect Dis. 2006 Dec 15; 194(12):1686-96.
Spudich S, Lollo N, Liegler T, Deeks SG, Price RW. PMID: 17109340.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
-
Immune-based therapy for HIV infection: are acute and chronic HIV infection different diseases? J Infect Dis. 2006 Dec 15; 194(12):1632-4.
Hunt PW, Deeks SG. PMID: 17109333.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
A plea for justice for jailed medical workers. Science. 2006 Nov 10; 314(5801):924-5.
Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA. PMID: 17062652.
View in:
PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
-
Rate of viral evolution and risk of losing future drug options in heavily pretreated, HIV-infected patients who continue to receive a stable, partially suppressive treatment regimen. Clin Infect Dis. 2006 Nov 15; 43(10):1329-36.
Hatano H, Hunt P, Weidler J, Coakley E, Hoh R, Liegler T, Martin JN, Deeks SG. PMID: 17051502.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
-
Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection. JAMA. 2006 Sep 27; 296(12):1498-506.
Rodríguez B, Sethi AK, Cheruvu VK, Mackay W, Bosch RJ, Kitahata M, Boswell SL, Mathews WC, Bangsberg DR, Martin J, Whalen CC, Sieg S, Yadavalli S, Deeks SG, Lederman MM. PMID: 17003398.
View in:
PubMed Mentions:
149 Fields:
Translation:
HumansCells
-
Rapid emergence of enfuvirtide resistance in HIV-1-infected patients: results of a clonal analysis. J Acquir Immune Defic Syndr. 2006 Sep; 43(1):60-4.
Lu J, Deeks SG, Hoh R, Beatty G, Kuritzkes BA, Martin JN, Kuritzkes DR. PMID: 16885776.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
-
Performance of human immunodeficiency virus type 1 gp41 assays for detecting enfuvirtide (T-20) resistance mutations. J Clin Microbiol. 2006 Sep; 44(9):3384-7.
Marcial M, Lu J, Deeks SG, Ziermann R, Kuritzkes DR. PMID: 16954280; PMCID: PMC1594677.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia. J Infect Dis. 2006 Oct 01; 194(7):926-30.
Hunt PW, Harrigan PR, Huang W, Bates M, Williamson DW, McCune JM, Price RW, Spudich SS, Lampiris H, Hoh R, Leigler T, Martin JN, Deeks SG. PMID: 16960780.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCellsCTClinical Trials
-
IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells. AIDS Res Ther. 2006 Jul 21; 3:18.
Nomura LE, Emu B, Hoh R, Haaland P, Deeks SG, Martin JN, McCune JM, Nixon DF, Maecker HT. PMID: 16859558; PMCID: PMC1562434.
View in:
PubMed Mentions:
8 Fields:
-
Antiretroviral treatment of HIV infected adults. BMJ. 2006 Jun 24; 332(7556):1489.
Deeks SG. PMID: 16793811; PMCID: PMC1482340.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
The risk of treatment versus the risk of HIV replication. Lancet. 2006 Jun 17; 367(9527):1955-6.
Deeks SG. PMID: 16782465.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses. J Virol. 2006 Jun; 80(12):6155-64.
Deeks SG, Schweighardt B, Wrin T, Galovich J, Hoh R, Sinclair E, Hunt P, McCune JM, Martin JN, Petropoulos CJ, Hecht FM. PMID: 16731954; PMCID: PMC1472617.
View in:
PubMed Mentions:
83 Fields:
Translation:
HumansCells
-
Bacterial meningitis among cochlear implant recipients--Canada, 2002. MMWR Suppl. 2006 Apr 28; 55(1):20-4.
Wilson-Clark SD, Squires S, Deeks S, Centers for Disease Control and Prevention (CDC). PMID: 16645578.
View in:
PubMed Mentions:
2 Translation:
Humans
-
The independent effect of drug resistance on T cell activation in HIV infection. AIDS. 2006 Mar 21; 20(5):691-9.
Hunt PW, Deeks SG, Bangsberg DR, Moss A, Sinclair E, Liegler T, Bates M, Tsao G, Lampiris H, Hoh R, Martin JN. PMID: 16514299.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Challenges of developing R5 inhibitors in antiretroviral naive HIV-infected patients. Lancet. 2006 Mar 04; 367(9512):711-3.
Deeks SG. PMID: 16517257.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
-
Adherence-resistance relationships for protease and non-nucleoside reverse transcriptase inhibitors explained by virological fitness. AIDS. 2006 Jan 09; 20(2):223-31.
Bangsberg DR, Acosta EP, Gupta R, Guzman D, Riley ED, Harrigan PR, Parkin N, Deeks SG. PMID: 16511415.
View in:
PubMed Mentions:
133 Fields:
Translation:
HumansCells
-
CD8 T cell effector maturation in HIV-1-infected children. Virology. 2006 Mar 30; 347(1):117-26.
Jordan KA, Furlan SN, Gonzalez VD, Karlsson AC, Quigley MF, Deeks SG, Rosenberg MG, Nixon DF, Sandberg JK. PMID: 16406047.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
A randomized pilot study comparing combination therapy plus enfuvirtide versus a treatment interruption followed by combination therapy plus enfuvirtide. Antivir Ther. 2006; 11(3):315-9.
Beatty G, Hunt P, Smith A, Hoh R, Huang W, Martin J, Deeks SG. PMID: 16759047.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
High-risk sexual behavior in adults with genotypically proven antiretroviral-resistant HIV infection. J Acquir Immune Defic Syndr. 2005 Dec 01; 40(4):463-71.
Chin-Hong PV, Deeks SG, Liegler T, Hagos E, Krone MR, Grant RM, Martin JN. PMID: 16280703.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Cerebrospinal fluid HIV infection and pleocytosis: relation to systemic infection and antiretroviral treatment. BMC Infect Dis. 2005 Nov 02; 5:98.
Spudich SS, Nilsson AC, Lollo ND, Liegler TJ, Petropoulos CJ, Deeks SG, Paxinos EE, Price RW. PMID: 16266436; PMCID: PMC1299327.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCells
-
Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment. J Virol. 2005 Nov; 79(22):14169-78.
Emu B, Sinclair E, Favre D, Moretto WJ, Hsue P, Hoh R, Martin JN, Nixon DF, McCune JM, Deeks SG. PMID: 16254352; PMCID: PMC1280210.
View in:
PubMed Mentions:
108 Fields:
Translation:
HumansCells
-
Partial treatment interruption of protease inhibitors augments HIV-specific immune responses in vertically infected pediatric patients. AIDS. 2005 Oct 14; 19(15):1575-85.
Legrand FA, Abadi J, Jordan KA, Davenport MP, Deeks SG, Fennelly GJ, Wiznia AA, Nixon DF, Rosenberg MG. PMID: 16184026.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCellsPHPublic Health
-
The relationship between nucleoside analogue treatment duration, insulin resistance, and fasting arterialized lactate level in patients with HIV infection. Clin Infect Dis. 2005 Nov 01; 41(9):1335-40.
Lo JC, Kazemi MR, Hsue PY, Martin JN, Deeks SG, Schambelan M, Mulligan K. PMID: 16206112.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Interruption of treatment with individual therapeutic drug classes in adults with multidrug-resistant HIV-1 infection. J Infect Dis. 2005 Nov 01; 192(9):1537-44.
Deeks SG, Hoh R, Neilands TB, Liegler T, Aweeka F, Petropoulos CJ, Grant RM, Martin JN. PMID: 16206068.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCellsCTClinical Trials
-
Cerebrospinal fluid signs of neuronal damage after antiretroviral treatment interruption in HIV-1 infection. AIDS Res Ther. 2005 Aug 18; 2:6.
Gisslén M, Rosengren L, Hagberg L, Deeks SG, Price RW. PMID: 16109178; PMCID: PMC1198215.
View in:
PubMed Mentions:
23 Fields:
-
Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen. AIDS. 2005 Jun 10; 19(9):989-90.
Cohan D, Feakins C, Wara D, Petru A, McNicholl I, Schillinger D, Lu J, Kuritzkes D, Deeks SG. PMID: 15905684.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCellsPHPublic Health
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Multidrug-resistant, dual-tropic HIV-1 and rapid progression. Lancet. 2005 Jun 4-10; 365(9475):1924-5.
Nixon DF, Deeks SG, Shacklett BL, Karlsson AC. PMID: 15936414.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Modified anthrax fusion proteins deliver HIV antigens through MHC Class I and II pathways. Vaccine. 2005 Jul 14; 23(32):4128-35.
McEvers K, Elrefaei M, Norris P, Deeks S, Martin J, Lu Y, Cao H. PMID: 15964481.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Isolated lopinavir resistance after virological rebound of a ritonavir/lopinavir-based regimen. AIDS. 2004 Sep 24; 18(14):1965-6.
Friend J, Parkin N, Liegler T, Martin JN, Deeks SG. PMID: 15353986.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Treating the latent reservoir of HIV. AIDS Read. 2004 Sep; 14(9):485-6.
Critchfield JM, Deeks SG. PMID: 15457601.
View in:
PubMed Mentions: Fields:
Translation:
Humans
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Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment. Blood. 2004 Dec 01; 104(12):3672-8.
Aandahl EM, Quigley MF, Moretto WJ, Moll M, Gonzalez VD, Sönnerborg A, Lindbäck S, Hecht FM, Deeks SG, Rosenberg MG, Nixon DF, Sandberg JK. PMID: 15308569.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Central memory CD4+ T cell responses in chronic HIV infection are not restored by antiretroviral therapy. J Immunol. 2004 Aug 01; 173(3):2184-9.
Elrefaei M, McElroy MD, Preas CP, Hoh R, Deeks S, Martin J, Cao H. PMID: 15265956.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCellsPHPublic Health
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Modeling the HIV protease inhibitor adherence-resistance curve by use of empirically derived estimates. J Infect Dis. 2004 Jul 01; 190(1):162-5.
Bangsberg DR, Porco TC, Kagay C, Charlebois ED, Deeks SG, Guzman D, Clark R, Moss A. PMID: 15195256.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Immunologic and virologic evolution during periods of intermittent and persistent low-level viremia. AIDS. 2004 Apr 30; 18(7):981-9.
Karlsson AC, Younger SR, Martin JN, Grossman Z, Sinclair E, Hunt PW, Hagos E, Nixon DF, Deeks SG. PMID: 15096800.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood. 2004 Aug 15; 104(4):942-7.
Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narváez AB, Hunt P, Martin JN, Kahn JO, Levy J, McGrath MS, Hecht FM. PMID: 15117761.
View in:
PubMed Mentions:
402 Fields:
Translation:
HumansCells
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Paradoxes of adherence and drug resistance to HIV antiretroviral therapy. J Antimicrob Chemother. 2004 May; 53(5):696-9.
Bangsberg DR, Moss AR, Deeks SG. PMID: 15044425.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansPHPublic Health
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Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection. Circulation. 2004 Apr 06; 109(13):1603-8.
Hsue PY, Lo JC, Franklin A, Bolger AF, Martin JN, Deeks SG, Waters DD. PMID: 15023877.
View in:
PubMed Mentions:
229 Fields:
Translation:
Humans
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The immune response to AIDS virus infection: good, bad, or both? J Clin Invest. 2004 Mar; 113(6):808-10.
Deeks SG, Walker BD. PMID: 15067312; PMCID: PMC362127.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1. J Infect Dis. 2004 Jan 15; 189(2):312-21.
Deeks SG, Martin JN, Sinclair E, Harris J, Neilands TB, Maecker HT, Hagos E, Wrin T, Petropoulos CJ, Bredt B, McCune JM. PMID: 14722897.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Antiretroviral drug treatment interruption in human immunodeficiency virus-infected adults: Clinical and pathogenetic implications for the central nervous system. J Neurovirol. 2004; 10 Suppl 1:44-51.
Price RW, Deeks SG. PMID: 14982739.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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Treatment of antiretroviral-drug-resistant HIV-1 infection. Lancet. 2003 Dec 13; 362(9400):2002-11.
Deeks SG. PMID: 14683662.
View in:
PubMed Mentions:
72 Fields:
Translation:
HumansCells
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Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cells. J Immunol Methods. 2003 Dec; 283(1-2):141-53.
Karlsson AC, Martin JN, Younger SR, Bredt BM, Epling L, Ronquillo R, Varma A, Deeks SG, McCune JM, Nixon DF, Sinclair E. PMID: 14659906.
View in:
PubMed Mentions:
93 Fields:
Translation:
HumansCells
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Assessing resistance costs of antiretroviral therapies via measures of future drug options. J Infect Dis. 2003 Oct 01; 188(7):1001-8.
Jiang H, Deeks SG, Kuritzkes DR, Lallemant M, Katzenstein D, Albrecht M, DeGruttola V. PMID: 14513420.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy. AIDS. 2003 Sep 05; 17(13):1907-15.
Hunt PW, Deeks SG, Rodriguez B, Valdez H, Shade SB, Abrams DI, Kitahata MM, Krone M, Neilands TB, Brand RJ, Lederman MM, Martin JN. PMID: 12960823.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansCells
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High levels of adherence do not prevent accumulation of HIV drug resistance mutations. AIDS. 2003 Sep 05; 17(13):1925-32.
Bangsberg DR, Charlebois ED, Grant RM, Holodniy M, Deeks SG, Perry S, Conroy KN, Clark R, Guzman D, Zolopa A, Moss A. PMID: 12960825.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Ann Intern Med. 2003 Aug 19; 139(4):258-66.
Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, Bacchetti P, McCune JM, Schambelan M. PMID: 12965981.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansCellsCTClinical Trials
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Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene. J Virol. 2003 Jun; 77(12):6743-52.
Karlsson AC, Deeks SG, Barbour JD, Heiken BD, Younger SR, Hoh R, Lane M, Sällberg M, Ortiz GM, Demarest JF, Liegler T, Grant RM, Martin JN, Nixon DF. PMID: 12767994; PMCID: PMC156163.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis. 2003 May 15; 187(10):1534-43.
Hunt PW, Martin JN, Sinclair E, Bredt B, Hagos E, Lampiris H, Deeks SG. PMID: 12721933.
View in:
PubMed Mentions:
445 Fields:
Translation:
HumansCells
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Absolute or total lymphocyte count as a marker for the CD4 T lymphocyte criterion for initiating antiretroviral therapy. AIDS. 2003 Apr 11; 17(6):917-9.
Jacobson MA, Liu L, Khayam-Bashi H, Deeks SG, Hecht FM, Kahn J. PMID: 12660541.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Persistence of drug-resistant HIV-1 after a structured treatment interruption and its impact on treatment response. AIDS. 2003 Feb 14; 17(3):361-70.
Deeks SG, Grant RM, Wrin T, Paxinos EE, Liegler T, Hoh R, Martin JN, Petropoulos CJ. PMID: 12556690.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Multiple measures of HIV burden in blood and tissue are correlated with each other but not with clinical parameters in aviremic subjects. AIDS. 2003 Jan 03; 17(1):53-63.
Anton PA, Mitsuyasu RT, Deeks SG, Scadden DT, Wagner B, Huang C, Macken C, Richman DD, Christopherson C, Borellini F, Lazar R, Hege KM. PMID: 12478069.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
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Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults. J Virol. 2002 Nov; 76(21):11104-12.
Barbour JD, Wrin T, Grant RM, Martin JN, Segal MR, Petropoulos CJ, Deeks SG. PMID: 12368352; PMCID: PMC136622.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV-1: clinical, phenotypic and genotypic correlates. AIDS. 2002 Oct 18; 16(15):F41-7.
Whitcomb JM, Huang W, Limoli K, Paxinos E, Wrin T, Skowron G, Deeks SG, Bates M, Hellmann NS, Petropoulos CJ. PMID: 12370521.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Is average adherence to HIV antiretroviral therapy enough? J Gen Intern Med. 2002 Oct; 17(10):812-3.
Bangsberg DR, Deeks SG. PMID: 12390559; PMCID: PMC1495121.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
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Effect of prolonged discontinuation of successful antiretroviral therapy on CD4+ T cell decline in human immunodeficiency virus-infected patients: implications for intermittent therapeutic strategies. J Infect Dis. 2002 Sep 15; 186(6):851-4.
Tebas P, Henry K, Mondy K, Deeks S, Valdez H, Cohen C, Powderly WG. PMID: 12198623.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy. Mol Ther. 2002 Jun; 5(6):788-97.
Deeks SG, Wagner B, Anton PA, Mitsuyasu RT, Scadden DT, Huang C, Macken C, Richman DD, Christopherson C, June CH, Lazar R, Broad DF, Jalali S, Hege KM. PMID: 12027564.
View in:
PubMed Mentions:
143 Fields:
Translation:
HumansCellsCTClinical Trials
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Relationship of CD8(+) T cell noncytotoxic anti-HIV response to CD4(+) T cell number in untreated asymptomatic HIV-infected individuals. Blood. 2002 Jun 01; 99(11):4225-7.
Castelli JC, Deeks SG, Shiboski S, Levy JA. PMID: 12010831.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Safety and antiviral activity at 48 weeks of lopinavir/ritonavir plus nevirapine and 2 nucleoside reverse-transcriptase inhibitors in human immunodeficiency virus type 1-infected protease inhibitor-experienced patients. J Infect Dis. 2002 Mar 01; 185(5):599-607.
Benson CA, Deeks SG, Brun SC, Gulick RM, Eron JJ, Kessler HA, Murphy RL, Hicks C, King M, Wheeler D, Feinberg J, Stryker R, Sax PE, Riddler S, Thompson M, Real K, Hsu A, Kempf D, Japour AJ, Sun E. PMID: 11865416.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCellsCTClinical Trials
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Duration and predictors of CD4 T-cell gains in patients who continue combination therapy despite detectable plasma viremia. AIDS. 2002 Jan 25; 16(2):201-7.
Deeks SG, Barbour JD, Grant RM, Martin JN. PMID: 11807304.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCells
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CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy. J Infect Dis. 2002 Feb 01; 185(3):315-23.
Deeks SG, Hoh R, Grant RM, Wrin T, Barbour JD, Narvaez A, Cesar D, Abe K, Hanley MB, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK. PMID: 11807713.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Supervised interruptions of antiretroviral therapy. AIDS. 2002; 16 Suppl 4:S157-69.
Deeks SG, Hirschel B. PMID: 12699013.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Hydroxyurea does not enhance the anti-HIV activity of low-dose tenofovir disoproxil fumarate. J Acquir Immune Defic Syndr. 2001 Dec 01; 28(4):336-9.
Deeks SG, Barditch-Crovo P, Collier A, Smith A, Miller M, McGowan I, Coakley DF. PMID: 11707669.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsCTClinical Trials
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Phase i/ii trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother. 2001 Oct; 45(10):2733-9.
Barditch-Crovo P, Deeks SG, Collier A, Safrin S, Coakley DF, Miller M, Kearney BP, Coleman RL, Lamy PD, Kahn JO, McGowan I, Lietman PS. PMID: 11557462; PMCID: PMC90724.
View in:
PubMed Mentions:
109 Fields:
Translation:
HumansCTClinical Trials
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Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. AIDS. 2001 Sep 28; 15(14):1749-56.
Teixeira L, Valdez H, McCune JM, Koup RA, Badley AD, Hellerstein MK, Napolitano LA, Douek DC, Mbisa G, Deeks S, Harris JM, Barbour JD, Gross BH, Francis IR, Halvorsen R, Asaad R, Lederman MM. PMID: 11579235.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansCells
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Durable HIV treatment benefit despite low-level viremia: reassessing definitions of success or failure. JAMA. 2001 Jul 11; 286(2):224-6.
Deeks SG. PMID: 11448286.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Cerebrospinal fluid response to structured treatment interruption after virological failure. AIDS. 2001 Jul 06; 15(10):1251-9.
Price RW, Paxinos EE, Grant RM, Drews B, Nilsson A, Hoh R, Hellmann NS, Petropoulos CJ, Deeks SG. PMID: 11426069.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Selected topics from the 8th Conference on Retroviruses and Opportunistic Infections. February 4-8, 2001. Chicago, Illinois. HIV Clin Trials. 2001 Jul-Aug; 2(4):366-86.
Sabin CA, Olmscheid B, Moyle G, Carr A, Boyle B, Cohen C, Cooper D, Deeks S, Gulick T, Saag M. PMID: 11590541.
View in:
PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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Impaired replication of protease inhibitor-resistant HIV-1 in human thymus. Nat Med. 2001 Jun; 7(6):712-8.
Stoddart CA, Liegler TJ, Mammano F, Linquist-Stepps VD, Hayden MS, Deeks SG, Grant RM, Clavel F, McCune JM. PMID: 11385509.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Primary and recombinant HIV type 1 strains resistant to protease inhibitors are pathogenic in mature human lymphoid tissues. AIDS Res Hum Retroviruses. 2001 Apr 10; 17(6):517-23.
Penn ML, Myers M, Eckstein DA, Liegler TJ, Hayden M, Mammano F, Clavel F, Deeks SG, Grant RM, Goldsmith MA. PMID: 11350665.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
International perspectives on antiretroviral resistance. Nonnucleoside reverse transcriptase inhibitor resistance. J Acquir Immune Defic Syndr. 2001 Mar 01; 26 Suppl 1:S25-33.
Deeks SG. PMID: 11264999.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
-
Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia. N Engl J Med. 2001 Feb 15; 344(7):472-80.
Deeks SG, Wrin T, Liegler T, Hoh R, Hayden M, Barbour JD, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK, Grant RM. PMID: 11172188.
View in:
PubMed Mentions:
165 Fields:
Translation:
HumansCellsCTClinical Trials
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Implications of antiretroviral resistance on viral fitness. Curr Opin Infect Dis. 2001 Feb; 14(1):23-8.
Nijhuis M, Deeks S, Boucher C. PMID: 11979111.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Protease inhibitor-resistant HIV-1 from patients with preserved CD4 cell counts is cytopathic in activated CD4 T lymphocytes. AIDS. 2001 Jan 26; 15(2):179-84.
Liegler TJ, Hayden MS, Lee KH, Hoh R, Deeks SG, Granta RM. PMID: 11216925.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Reassessing the goal of antiretroviral therapy in the heavily pre-treated HIV-infected patient. AIDS. 2001 Jan 05; 15(1):117-9.
Deeks SG, Martin JN. PMID: 11192853.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med. 2001 Jan; 7(1):73-9.
Napolitano LA, Grant RM, Deeks SG, Schmidt D, De Rosa SC, Herzenberg LA, Herndier BG, Andersson J, McCune JM. PMID: 11135619.
View in:
PubMed Mentions:
174 Fields:
Translation:
HumansCells
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Loss of antiretroviral drug susceptibility at low viral load during early virological failure in treatment-experienced patients. AIDS. 2000 Dec 22; 14(18):2877-87.
Parkin NT, Deeks SG, Wrin MT, Yap J, Grant RM, Lee KH, Heeren D, Hellmanna NS, Petropoulos CJ. PMID: 11153669.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCellsCTClinical Trials
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Prolonged survival and tissue trafficking following adoptive transfer of CD4zeta gene-modified autologous CD4(+) and CD8(+) T cells in human immunodeficiency virus-infected subjects. Blood. 2000 Aug 01; 96(3):785-93.
Mitsuyasu RT, Anton PA, Deeks SG, Scadden DT, Connick E, Downs MT, Bakker A, Roberts MR, June CH, Jalali S, Lin AA, Pennathur-Das R, Hege KM. PMID: 10910888.
View in:
PubMed Mentions:
169 Fields:
Translation:
HumansCellsCTClinical Trials
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Determinants of virological response to antiretroviral therapy: implications for long-term strategies. Clin Infect Dis. 2000 Jun; 30 Suppl 2:S177-84.
Deeks SG. PMID: 10860903.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Factors influencing T-cell turnover in HIV-1-seropositive patients. J Clin Invest. 2000 Mar; 105(5):R1-8.
McCune JM, Hanley MB, Cesar D, Halvorsen R, Hoh R, Schmidt D, Wieder E, Deeks S, Siler S, Neese R, Hellerstein M. PMID: 10712441; PMCID: PMC377453.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansCells
-
Reversal of human immunodeficiency virus type 1-associated hematosuppression by effective antiretroviral therapy. Clin Infect Dis. 2000 Mar; 30(3):504-10.
Huang SS, Barbour JD, Deeks SG, Huang JS, Grant RM, Ng VL, McCune JM. PMID: 10722435.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Sustained CD4+ T cell response after virologic failure of protease inhibitor-based regimens in patients with human immunodeficiency virus infection. J Infect Dis. 2000 Mar; 181(3):946-53.
Deeks SG, Barbour JD, Martin JN, Swanson MS, Grant RM. PMID: 10720517.
View in:
PubMed Mentions:
51 Fields:
Translation:
Humans
-
Efficacy and safety of adefovir dipivoxil with antiretroviral therapy: a randomized controlled trial. JAMA. 1999 Dec 22-29; 282(24):2305-12.
Kahn J, Lagakos S, Wulfsohn M, Cherng D, Miller M, Cherrington J, Hardy D, Beall G, Cooper R, Murphy R, Basgoz N, Ng E, Deeks S, Winslow D, Toole JJ, Coakley D. PMID: 10612317.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCellsCTClinical Trials
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Salmonella typhimurium definitive type 104 isolates in British Columbia, 1997-1998. Can Commun Dis Rep. 1999 Aug 01; 25(15):129-33.
Buxton J, Fyfe M, King A, Deeks S, Dore K, Ahmed R, Khakhria R, Paccagnella A, Hockin J. PMID: 10466255.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Pneumococcal immunization and public health: the Canadian experience. Vaccine. 1999 Jul 30; 17 Suppl 1:S105-8.
Spika JS, Keresz D, Deeks S, Talbot JA. PMID: 10471193.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCellsPHPublic Health
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Time course of cerebrospinal fluid responses to antiretroviral therapy: evidence for variable compartmentalization of infection. AIDS. 1999 Jun 18; 13(9):1051-61.
Staprans S, Marlowe N, Glidden D, Novakovic-Agopian T, Grant RM, Heyes M, Aweeka F, Deeks S, Price RW. PMID: 10397535.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome. J Infect Dis. 1999 Jun; 179(6):1375-81.
Deeks SG, Hellmann NS, Grant RM, Parkin NT, Petropoulos CJ, Becker M, Symonds W, Chesney M, Volberding PA. PMID: 10228057.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCellsCTClinical Trials
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HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: response to both initial and salvage therapy. AIDS. 1999 Apr 16; 13(6):F35-43.
Deeks SG, Hecht FM, Swanson M, Elbeik T, Loftus R, Cohen PT, Grant RM. PMID: 10397555.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Failure of physicians to consider the diagnosis of pertussis in children. Clin Infect Dis. 1999 Apr; 28(4):840-6.
Deeks S, De Serres G, Boulianne N, Duval B, Rochette L, Déry P, Halperin S. PMID: 10825048.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansPHPublic Health
-
Failure of HIV-1 protease inhibitors to fully suppress viral replication. Implications for salvage therapy. Adv Exp Med Biol. 1999; 458:175-82.
Deeks SG. PMID: 10549390.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. Nat Med. 1999 Jan; 5(1):83-9.
Hellerstein M, Hanley MB, Cesar D, Siler S, Papageorgopoulos C, Wieder E, Schmidt D, Hoh R, Neese R, Macallan D, Deeks S, McCune JM. PMID: 9883844.
View in:
PubMed Mentions:
160 Fields:
Translation:
HumansCells
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Sustained CD4 responses after virological failure of protease inhibitor-containing therapy. Antivir Ther. 1999; 4 Suppl 3:7-11.
Deeks SG, Grant RM. PMID: 16021865.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Salmonella Oranienburg, Ontario. Can Commun Dis Rep. 1998 Nov 15; 24(22):177-8; discussion 178-9.
Deeks S, Ellis A, Ciebin B, Khakhria R, Naus M, Hockin J. PMID: 9844252.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsPHPublic Health
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Safety, pharmacokinetics, and antiretroviral activity of intravenous 9-[2-(R)-(Phosphonomethoxy)propyl]adenine, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults. Antimicrob Agents Chemother. 1998 Sep; 42(9):2380-4.
Deeks SG, Barditch-Crovo P, Lietman PS, Hwang F, Cundy KC, Rooney JF, Hellmann NS, Safrin S, Kahn JO. PMID: 9736567; PMCID: PMC105837.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCellsCTClinical Trials
-
Should we argue with success? AIDS Clin Care. 1998 Sep; 10(9):68, 72.
Deeks SG, Sax PE. PMID: 11365809.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Activity of a ritonavir plus saquinavir-containing regimen in patients with virologic evidence of indinavir or ritonavir failure. AIDS. 1998 Jul 09; 12(10):F97-102.
Deeks SG, Grant RM, Beatty GW, Horton C, Detmer J, Eastman S. PMID: 9677159.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Antiretroviral therapy for HIV infection: promises and problems. JAMA. 1998 May 06; 279(17):1343-4.
Volberding PA, Deeks SG. PMID: 9582033.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Antiretroviral agents: the next generation. AIDS Clin Care. 1998 May; 10(5):33-6, 39-40.
Deeks SG. PMID: 11365427.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Fifth Conference on Retroviruses & Opportunistic Infections. Interview by Ron Baker. Newsline People AIDS Coalit N Y. 1998 Mar; 7-14.
Follansbee S, Deeks S, Bartnoff H. PMID: 11367453.
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Humans
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Clinical implications of virological "failure": interview with Steven Deeks, M.D., San Francisco General Hospital. Interview by John S. James. AIDS Treat News. 1998 Feb 20; (No 289):1-6.
Deeks S. PMID: 11365047.
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HumansCells
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Practical issues regarding the use of antiretroviral therapy for HIV infection. West J Med. 1998 Feb; 168(2):133-9.
Deeks SG. PMID: 9499754; PMCID: PMC1304849.
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2 Fields:
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HumansCells
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The safety and efficacy of adefovir dipivoxil, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults: a randomized, double-blind, placebo-controlled trial. J Infect Dis. 1997 Dec; 176(6):1517-23.
Deeks SG, Collier A, Lalezari J, Pavia A, Rodrigue D, Drew WL, Toole J, Jaffe HS, Mulato AS, Lamy PD, Li W, Cherrington JM, Hellmann N, Kahn J. PMID: 9395363.
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20 Fields:
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HumansCellsCTClinical Trials
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Surveillance of invasive meningococcal disease in Canada, 1995-1996. Can Commun Dis Rep. 1997 Aug 15; 23(16):121-5.
Deeks S, Kertesz D, Ryan A, Johnson W, Ashton F. PMID: 9439039.
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6 Fields:
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Humans
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Variance of plasma human immunodeficiency virus type 1 RNA levels measured by branched DNA within and between days. J Infect Dis. 1997 Aug; 176(2):514-7.
Deeks SG, Coleman RL, White R, Pachl C, Schambelan M, Chernoff DN, Feinberg MB. PMID: 9237721.
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8 Fields:
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Genotypic-resistance assays and antiretroviral therapy. Lancet. 1997 May 24; 349(9064):1489-90.
Deeks SG, Abrams DI. PMID: 9167453.
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6 Fields:
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HumansCells
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New principles of HIV-related medical care. Focus. 1997 Apr; 12(5):5-7.
Deeks SG. PMID: 11364329.
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Humans
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HIV-1 protease inhibitors. A review for clinicians. JAMA. 1997 Jan 08; 277(2):145-53.
Deeks SG, Smith M, Holodniy M, Kahn JO. PMID: 8990341.
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126 Fields:
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Curdlan sulfate (CRDS) in a 21-day intravenous tolerance study in human immunodeficiency virus (HIV) and cytomegalovirus (CMV) infected patients: indication of anti-CMV activity with low toxicity. J Med. 1997; 28(1-2):108-28.
Gordon M, Deeks S, De Marzo C, Goodgame J, Guralnik M, Lang W, Mimura T, Pearce D, Kaneko Y. PMID: 9249617.
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7 Fields:
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HumansCTClinical Trials
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HIV-1 protease inhibitors. AIDS Clin Rev. 1997-1998; 145-85.
Deeks SG, Volberding PA. PMID: 9305448.
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3 Fields:
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Humans
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Randomised trial of MNrgp120 HIV-1 vaccine in symptomless HIV-1 infection. Lancet. 1996 Dec 07; 348(9041):1547-51.
Eron JJ, Ashby MA, Giordano MF, Chernow M, Reiter WM, Deeks SG, Lavelle JP, Conant MA, Yangco BG, Pate PG, Torres RA, Mitsuyasu RT, Twaddell T. PMID: 8950881.
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8 Fields:
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HumansCellsCTClinical Trials
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An approach to antiretroviral treatment of HIV disease. Combined antiretroviral therapy: the emerging role. Hosp Pract (1995). 1995 Aug; 30 Suppl 1:23-31.
Deeks S, Volberding P. PMID: 7635914.
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1 Fields:
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HumansCells
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Maintenance of normal rat mammary epithelial cells by insulin and insulin-like growth factor 1. Exp Cell Res. 1988 Feb; 174(2):448-60.
Deeks S, Richards J, Nandi S. PMID: 3276539.
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13 Fields:
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AnimalsCells