"Drug Repositioning" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The deliberate and methodical practice of finding new applications for existing drugs.
| Descriptor ID |
D058492
|
| MeSH Number(s) |
E05.295.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Repositioning".
Below are MeSH descriptors whose meaning is more specific than "Drug Repositioning".
This graph shows the total number of publications written about "Drug Repositioning" by people in this website by year, and whether "Drug Repositioning" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 1 | 2 |
| 2011 | 4 | 0 | 4 |
| 2013 | 1 | 3 | 4 |
| 2014 | 3 | 2 | 5 |
| 2015 | 6 | 1 | 7 |
| 2016 | 3 | 3 | 6 |
| 2017 | 8 | 4 | 12 |
| 2018 | 4 | 8 | 12 |
| 2019 | 3 | 7 | 10 |
| 2020 | 19 | 16 | 35 |
| 2021 | 12 | 15 | 27 |
| 2022 | 0 | 9 | 9 |
| 2023 | 2 | 6 | 8 |
| 2024 | 2 | 1 | 3 |
Below are the most recent publications written about "Drug Repositioning" by people in Profiles.
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Repurposing of the analgesic Neurotropin for MASLD/MASH treatment. Hepatol Commun. 2024 Aug 01; 8(8).
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A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models. Nat Commun. 2024 Jul 15; 15(1):5943.
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Colloidal Aggregation Confounds Cell-Based Covid-19 Antiviral Screens. J Med Chem. 2024 Jun 27; 67(12):10263-10274.
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Repurposing calcium-sensing receptor activator drug cinacalcet for ADPKD treatment. Transl Res. 2024 03; 265:17-25.
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Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer. Nat Commun. 2023 10 10; 14(1):6332.
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Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients. PLoS Comput Biol. 2023 05; 19(5):e1011050.
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Repurposing the KCa3.1 Blocker Senicapoc for Ischemic Stroke. Transl Stroke Res. 2024 Jun; 15(3):518-532.
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AI-driven drug repurposing and binding pose meta dynamics identifies novel targets for monkeypox virus. J Infect Public Health. 2023 May; 16(5):799-807.
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Potential treatments of COVID-19: Drug repurposing and therapeutic interventions. J Pharmacol Sci. 2023 May; 152(1):1-21.
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Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. Nat Genet. 2023 02; 55(2):291-300.