DNA Breaks, Double-Stranded

"DNA Breaks, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
Interruptions in the sugar-phosphate backbone of DNA, across both strands adjacently.


expand / collapse Publications
This graph shows the total number of publications written about "DNA Breaks, Double-Stranded" by people in this website by year, and whether "DNA Breaks, Double-Stranded" was a major or minor topic of these publications.
Below are the most recent publications written about "DNA Breaks, Double-Stranded" by people in Profiles.
  1. The chromatin-associated 53BP1 ortholog, HSR-9, regulates recombinational repair and X chromosome segregation in the Caenorhabditis elegans germ line. Genetics. 2024 Aug 07; 227(4).
    View in: PubMed
  2. Increased AID results in mutations at the CRLF2 locus implicated in Latin American ALL health disparities. Nat Commun. 2024 Jul 27; 15(1):6331.
    View in: PubMed
  3. Changes in repair pathways of radiation-induced DNA double-strand breaks at the midblastula transition in Xenopus embryo. J Radiat Res. 2024 May 23; 65(3):315-322.
    View in: PubMed
  4. Developmental progression of DNA double-strand break repair deciphered by a single-allele resolution mutation classifier. Nat Commun. 2024 Mar 23; 15(1):2629.
    View in: PubMed
  5. Template switching between the leading and lagging strands at replication forks generates inverted copy number variants through hairpin-capped extrachromosomal DNA. PLoS Genet. 2024 Jan; 20(1):e1010850.
    View in: PubMed
  6. Chromatin compartmentalization regulates the response to DNA damage. Nature. 2023 Nov; 623(7985):183-192.
    View in: PubMed
  7. Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration. Cell. 2023 09 28; 186(20):4404-4421.e20.
    View in: PubMed
  8. Therapy-induced APOBEC3A drives evolution of persistent cancer cells. Nature. 2023 Aug; 620(7973):393-401.
    View in: PubMed
  9. The flexible and iterative steps within the NHEJ pathway. Prog Biophys Mol Biol. 2023 Jul-Aug; 180-181:105-119.
    View in: PubMed
  10. Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats. Nature. 2023 04; 616(7957):504-509.
    View in: PubMed