"Notochord" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cartilaginous rod of mesodermal cells at the dorsal midline of all CHORDATE embryos. In lower vertebrates, notochord is the backbone of support. In the higher vertebrates, notochord is a transient structure, and segments of the vertebral column will develop around it. Notochord is also a source of midline signals that pattern surrounding tissues including the NEURAL TUBE development.
| Descriptor ID |
D009672
|
| MeSH Number(s) |
A16.660
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Notochord".
Below are MeSH descriptors whose meaning is more specific than "Notochord".
This graph shows the total number of publications written about "Notochord" by people in this website by year, and whether "Notochord" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 3 | 3 |
| 1997 | 1 | 2 | 3 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 2 | 3 |
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2008 | 4 | 0 | 4 |
| 2010 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2023 | 2 | 0 | 2 |
Below are the most recent publications written about "Notochord" by people in Profiles.
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Conserved enhancers control notochord expression of vertebrate Brachyury. Nat Commun. 2023 10 18; 14(1):6594.
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Diverse logics and grammar encode notochord enhancers. Cell Rep. 2023 02 28; 42(2):112052.
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Spontaneous, Intrasphenoidal Rupture of Ecchordosis Physaliphora with Pneumocephalus Captured During Serial Imaging and Clinical Follow-Up: Pathoanatomic Features and Management. World Neurosurg. 2020 09; 141:85-90.
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NOTO Transcription Factor Directs Human Induced Pluripotent Stem Cell-Derived Mesendoderm Progenitors to a Notochordal Fate. Cells. 2020 02 24; 9(2).
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Human iPSCs can be differentiated into notochordal cells that reduce intervertebral disc degeneration in a porcine model. Theranostics. 2019; 9(25):7506-7524.
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A vertebrate-specific and essential role for osterix in osteogenesis revealed by gene knockout in the teleost medaka. Development. 2017 01 15; 144(2):265-271.
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Syntax compensates for poor binding sites to encode tissue specificity of developmental enhancers. Proc Natl Acad Sci U S A. 2016 06 07; 113(23):6508-13.
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Endoscopic resection of a giant intradural retroclival ecchordosis physaliphora: surgical technique and literature review. World Neurosurg. 2014 Nov; 82(5):912.e21-6.
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A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12. Dis Model Mech. 2014 Jul; 7(7):907-13.
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An anteroposterior wave of vascular inhibitor downregulation signals aortae fusion along the embryonic midline axis. Development. 2010 Nov; 137(21):3697-706.