A variety of deficits in
GABAergic markers in the PFC have been reported in postmortem SZ brain studies, which has indicated that SZ is associated with lower inhibitory transmission.
CSF hypozincaemia activates N-Methy-D-Aspartate receptors or disinhibits
GABAergic action, thus resulting in febrile convulsion.
GABAergic signaling by identified neurons in circuits that control behavior is emphasized because this role could provide insights into functions that are generalizable across phylogeny.
These three genes involved in the glutamatergic,
GABAergic and dopaminergic synapse pathways.
The researchers transplanted human induced pluripotent stem cell (iPSC)-derived
GABAergic progenitor cells into the hippocampus in an animal model of early temporal lobe epilepsy.
The results suggest that iPSC-derived
GABAergic cell therapy has the promise for providing a long-lasting seizure control and relieving comorbidities associated with epilepsy.
Although the efficacy of clonazepam in RLS treatment has been controversial lately, complaints tend to improve in both diseases after
GABAergic drugs such as clonazepam or gabapentin (5,6).
"This is a drug that has a unique effect on the
GABAergic system.
Input from these afferents releases the neurotransmitter substance P at neurokinin-1 receptors on
GABAergic interneurons in the caudal NTS.
Bloom is targeting rare epileptic syndromes with orally-delivered pharmaceutical compositions of specific combined strains of naturally-occurring microbes that are designed to act on the
GABAergic system.
Direct evidence for
GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABArho receptors.