clavulanate


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clavulanate

 [klav´u-lah-nāt]
a β-lactamase inhibitor used as the potassium salt in combination with penicillins in treating infections caused by β-lactamase–producing organisms.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
For bacteria isolated from diabetic foot infection, the following antibiotics were used against the causative agents: amikacin (30ug), (20ug of amoxicillin + 10ug of clavulanate), cefotaxime (30ug), ceftazidime (30ug), ciprofloxacin (5ug), erythromycin (15ug), gentamycin (10ug), oxacillin (1ug), piperacillin (100ug) and vancomycin (30ug).
Empirical antibiotic which can be selected for oral administration include amoxycillin clavulanate, TMP-SMX, cefixime, sefpodoxim, cefprozil, cefuroxime axetil and cefalexin.
Augmentin ES-600 is a new powder that when reconstituted gives an orange-raspberry suspension that contains 600 mg amoxicillin and 42.9 mg clavulanate potassium.
As a last resort, the Belgian physicians decided to try clavulanate and meropenem, the combination therapy they had read about in Blanchard's Science paper.
Hoberman declared grant support from Ricoh Innovations and holding pending patents for a reduced clavulanate concentration version of amoxicillin-clavulanate potassium, and a method and device for aiding in the diagnosis of otitis media.
For Gram-negative isolates, the following Neo-Sensitabs tablets were examined: amoxicillin 30 [micro]g, piperacillin 100 [micro]g, amoxicillin/ clavulanate 30/15 [micro]g, piperacillin/tazobactam 100/10 [micro]g, cefazolin 60 [micro]g, cefuroxime 60 [micro]g, cefotaxime 30 [micro]g, cefotaxime/clavulanate 30/10 [micro] g, ceftazidime 30 [micro] g, ceftazidime/clavulanate 30/10 [micro] g, cefepime 30 [micro] g, cefepime/clavulanate 30/10 [micro]g, imipenem 15 [micro] g, amikacin 40 [micro] g, kanamycin 100 [micro] g, gentamicin 40 [micro] g, nalidixic acid 130 [micro] g, ciprofloxacin 10 [micro] g, nitrofurantoin 260 [micro] g, fosfomycin 70 [micro] g, trimethoprim/sulfamethoxazole 5.2/240 [micro] g, chloramphenicol 60 [micro] g, doxycycline 80 [micro] g and tetracycline 80 [micro] g.
ESBL production was detected by the double disk approximation test using clavulanate containing disk and four different cephalosporin disks.
The dog lived mainly outdoors and had a 1-week history of depression, fever (40.1[degrees]C), and swelling of the left tarsus, which resolved with administration of ampicillin and clavulanate. On examination, the dog was febrile (39.8[degrees]C) and had marked dyspnea with mild cyanosis.
A recent Finnish study finds that Augmentin (a combination of amoxicillin and clavulanate) does make a difference.
Clinical Cure Rates in Uncomplicated Cystitis Amoxicillin- Ciprofloxacin Clavulanate 2 weeks 98% 80% 4 weeks 90% 77% 8 weeks 84% 70% 12 weeks 79% 66% Source: Dr.